metoclopramide has been researched along with Liver Cirrhosis in 17 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind comparison of metoclopramide versus placebo was performed on 8 cirrhotic patients with nausea (8 cases) and heartburn (3 of the 8 cases) plus mild portal-systemic encephalopathy." | 9.05 | Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial. ( Ballesteros, A; Briones, A; Garcia Ramos, G; Garza, J; Rosales, J; Strauss, R; Uribe, M; Villalobos, A, 1985) |
| "A double-blind comparison of metoclopramide versus placebo was performed on 8 cirrhotic patients with nausea (8 cases) and heartburn (3 of the 8 cases) plus mild portal-systemic encephalopathy." | 5.05 | Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial. ( Ballesteros, A; Briones, A; Garcia Ramos, G; Garza, J; Rosales, J; Strauss, R; Uribe, M; Villalobos, A, 1985) |
| "The effects of metoclopramide on blood flow in portal and left gastric veins and cardiovascular haemodynamic variables were studied in 30 patients with both liver cirrhosis and oesophageal varices." | 3.69 | Portal venous blood flow unaltered in cirrhotic patients given metoclopramide injections. ( Hashizume, M; Ohta, M; Sugimachi, K; Tanoue, K; Tomikawa, M; Ueno, K, 1995) |
| "Growth hormone (GH) secretory response to metoclopramide (MCP) administration was evaluated in 9 male patients with liver cirrhosis and in 6 normal controls." | 3.66 | Effect of metoclopramide on serum growth hormone levels in cirrhotic men. ( Chiodera, P; Coiro, V; Mancini, P; Pelosi, G; Salvi, M; Volpi, R, 1983) |
| "Patients with preascitic liver cirrhosis have an increased central plasma volume, and, for any given plasma aldosterone concentration, they excrete less sodium than healthy controls." | 1.30 | Renal distal tubular handling of sodium in central fluid volume homoeostasis in preascitic cirrhosis. ( Baraldi, E; Castellana, CN; De Santis, MC; Ferrari, A; Manenti, F; Sansoè, G, 1999) |
| " In contrast, the median oral bioavailability was considerably higher in patients with cirrhosis of the liver (82%) than in patients with normal liver function (60%)." | 1.27 | Absolute bioavailability of metoclopramide given orally or by enema in patients with normal liver function or with cirrhosis of the liver. ( Achtert, G; Brockmann, P; Gatzen, M; Hausleiter, HJ; Hellenbrecht, D; Hellstern, A; Leuschner, U; Manus, B; Saller, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Vijayaraghavan, R | 1 |
| Maiwall, R | 1 |
| Arora, V | 1 |
| Choudhary, A | 1 |
| Benjamin, J | 1 |
| Aggarwal, P | 1 |
| Jamwal, KD | 1 |
| Kumar, G | 1 |
| Joshi, YK | 1 |
| Sarin, SK | 1 |
| Sansoè, G | 3 |
| Silvano, S | 2 |
| Rosina, F | 2 |
| Smedile, A | 1 |
| Rizzetto, M | 1 |
| Volpi, R | 1 |
| Coiro, V | 1 |
| Salvi, M | 1 |
| Pelosi, G | 1 |
| Mancini, P | 1 |
| Chiodera, P | 1 |
| Miskowiak, J | 1 |
| Burcharth, F | 1 |
| Jensen, LI | 1 |
| Ohta, M | 1 |
| Tomikawa, M | 1 |
| Hashizume, M | 1 |
| Ueno, K | 1 |
| Tanoue, K | 1 |
| Sugimachi, K | 1 |
| Ferrari, A | 2 |
| Baraldi, E | 2 |
| Castellana, CN | 2 |
| De Santis, MC | 1 |
| Manenti, F | 2 |
| Biava, A | 1 |
| Bonardi, L | 1 |
| Albani, F | 2 |
| Tamè, MR | 1 |
| De Palma, R | 2 |
| Bernardi, M | 2 |
| Ljubicić, N | 1 |
| Taranto, D | 1 |
| Suozzo, R | 1 |
| de Sio, I | 1 |
| Romano, M | 1 |
| Caporaso, N | 1 |
| Del Vecchio Blanco, C | 1 |
| Coltorti, M | 1 |
| Trevisani, F | 1 |
| Malatesta, R | 1 |
| Baraldini, M | 1 |
| Cursaro, C | 1 |
| Gasbarrini, G | 1 |
| Riva, R | 1 |
| Contin, M | 1 |
| Baruzzi, A | 1 |
| Hellstern, A | 1 |
| Hellenbrecht, D | 1 |
| Saller, R | 1 |
| Gatzen, M | 1 |
| Manus, B | 1 |
| Achtert, G | 1 |
| Brockmann, P | 1 |
| Hausleiter, HJ | 1 |
| Leuschner, U | 1 |
| Sauerbruch, T | 1 |
| Braillon, A | 1 |
| Tribout, B | 1 |
| Reix, N | 1 |
| Capron, JP | 1 |
| Uribe, M | 1 |
| Ballesteros, A | 1 |
| Strauss, R | 1 |
| Rosales, J | 1 |
| Garza, J | 1 |
| Villalobos, A | 1 |
| Briones, A | 1 |
| Garcia Ramos, G | 1 |
| Stellamor, K | 1 |
3 trials available for metoclopramide and Liver Cirrhosis
| Article | Year |
|---|---|
Reversal of Feed Intolerance by Prokinetics Improves Survival in Critically Ill Cirrhosis Patients.
Topics: Critical Illness; Enteral Nutrition; Erythromycin; Humans; Intensive Care Units; Liver Cirrhosis; Me | 2022 |
Effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients.
Topics: Double-Blind Method; Esophageal and Gastric Varices; Esophagogastric Junction; Female; Humans; Liver | 1990 |
Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial.
Topics: Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Gastroesophageal Reflux; Hep | 1985 |
14 other studies available for metoclopramide and Liver Cirrhosis
| Article | Year |
|---|---|
Evidence of a dynamic aldosterone-independent distal tubular control of renal sodium excretion in compensated liver cirrhosis.
Topics: Adult; Aged; Aldosterone; Dopamine Antagonists; Female; Humans; Kidney; Kidney Tubules, Distal; Lith | 2005 |
Effect of metoclopramide on serum growth hormone levels in cirrhotic men.
Topics: Adult; Estradiol; Growth Hormone; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Ma | 1983 |
Effect of lower oesophageal sphincter on oesophageal varices. A portographic study.
Topics: Butylscopolammonium Bromide; Depression, Chemical; Esophageal and Gastric Varices; Esophagogastric J | 1981 |
Portal venous blood flow unaltered in cirrhotic patients given metoclopramide injections.
Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Case-Control Studies; Double-Blind Method; Esop | 1995 |
Renal distal tubular handling of sodium in central fluid volume homoeostasis in preascitic cirrhosis.
Topics: Adult; Aged; Aldosterone; Case-Control Studies; Creatinine; Dopamine Antagonists; Female; Humans; Ki | 1999 |
Dopaminergic control of renal tubular function in patients with compensated cirrhosis.
Topics: Adult; Aged; Aldosterone; Case-Control Studies; Dopamine; Dopamine Antagonists; Female; Humans; Imme | 2002 |
Kinetics of intravenous metoclopramide in patients with hepatic cirrhosis.
Topics: Adult; Female; Half-Life; Humans; Injections, Intravenous; Liver Cirrhosis; Male; Metoclopramide; Mi | 1991 |
Effect of metoclopramide on portal blood flow in patients with liver cirrhosis, measured by the pulsed Doppler system.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Female; Hemodynamics; Humans; Hypertension, Portal | 1990 |
Unaltered dopaminergic modulation of aldosterone secretion in cirrhosis.
Topics: Adult; Aged; Aldosterone; Glomerular Filtration Rate; Humans; Liver Cirrhosis; Male; Metoclopramide; | 1988 |
Liquid chromatographic analysis of metoclopramide with fluorescence detection in cirrhotic patients.
Topics: Chromatography, High Pressure Liquid; Humans; Liver Cirrhosis; Metoclopramide; Spectrometry, Fluores | 1987 |
Absolute bioavailability of metoclopramide given orally or by enema in patients with normal liver function or with cirrhosis of the liver.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Biological Availability; Enema; Humans; Inject | 1987 |
[Commentary on an abstract. Effects of metoclopramide and domperidone on azygous venous blood flow in patients with cirrhosis and portal hypertension].
Topics: Azygos Vein; Domperidone; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Circul | 1987 |
[Are metoclopramide and propranolol contraindicated, like nonsteroidal anti-inflammatory agents, in patients with cirrhosis and ascites?].
Topics: Anti-Inflammatory Agents; Ascites; Diuretics; Drug Therapy, Combination; Humans; Liver Cirrhosis; Me | 1986 |
[A new possibility for routine x-ray examination of the small intestine].
Topics: Achlorhydria; Biliary Tract Diseases; Colonic Diseases; Contrast Media; Gastrointestinal Motility; H | 1973 |