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metoclopramide and Intraocular Pressure

metoclopramide has been researched along with Intraocular Pressure in 8 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits."7.70Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998)
"The interaction between bromocriptine and metoclopramide on intraocular pressure (IOP), pupil diameter, and other parameters were studied in healthy volunteers."5.05Stimulation of dopamine receptors (type 2) lowers human intraocular pressure. ( Mekki, QA; Turner, P, 1985)
"Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits."3.70Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998)
"The dopamine (DA2) receptor agonist 2,10,11-trihydroxy-N-n-propylnoraporphine (TNPA) was tested for effects on 1) intraocular pressure (IOP), 2) aqueous humor flow rate, 3) electrically induced contractions of the cat nictitating membrane, 4) 3H-NE release from isolated rabbit iris-ciliary bodies and 5) cAMP accumulation in the isolated rabbit iris-ciliary body."3.68Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine. ( Chu, TC; Ogidigben, M; Potter, DE, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Potter, DE5
Burke, JA2
Chang, FW1
Ogidigben, M1
Chu, TC2
Ogidigben, MJ3
Heath, AR1
Liao, SL1
Hung, PT1
Chen, YC1
Lan, WL1
Mekki, QA2
Turner, P2

Trials

2 trials available for metoclopramide and Intraocular Pressure

ArticleYear
Safety and ocular hypotensive efficacy of a single dose of metoclopramide or droperidol in healthy subjects.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:2

    Topics: Adult; Dopamine Antagonists; Droperidol; Female; Humans; Intraocular Pressure; Male; Metoclopramide

1999
Stimulation of dopamine receptors (type 2) lowers human intraocular pressure.
    The British journal of ophthalmology, 1985, Volume: 69, Issue:12

    Topics: Bromocriptine; Drug Interactions; Humans; Intraocular Pressure; Male; Metoclopramide; Prolactin; Pup

1985

Other Studies

6 other studies available for metoclopramide and Intraocular Pressure

ArticleYear
Alteration in ocular function induced by phenylethylamine analogs of dopamine.
    Current eye research, 1984, Volume: 3, Issue:6

    Topics: Animals; Blinking; Blood Pressure; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Int

1984
Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Aporphines; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Dopamine Agents; Drug Interactio

1993
Ocular actions of an octahydrobenzo[f]quinoline: Ha117.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: Animals; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Domperidone; Dopamine Agents; Electric Stimu

1993
Lisuride acts at multiple sites to induce ocular hypotension and mydriasis.
    Pharmacology, 1998, Volume: 57, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Ocular inhibitory effects of the dopamine DA2 agonist (Ha-118) in cats and rabbits.
    Journal of autonomic pharmacology, 1990, Volume: 10, Issue:3

    Topics: Animals; Cats; Dopamine Agents; Electric Stimulation; Female; In Vitro Techniques; Intraocular Press

1990
Dopamine-2 receptor blockade does not affect the ocular hypotensive action of timolol.
    The British journal of ophthalmology, 1988, Volume: 72, Issue:8

    Topics: Adult; Female; Humans; Intraocular Pressure; Male; Metoclopramide; Receptors, Dopamine; Time Factors

1988