metoclopramide has been researched along with Intraocular Pressure in 8 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits." | 7.70 | Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998) |
| "The interaction between bromocriptine and metoclopramide on intraocular pressure (IOP), pupil diameter, and other parameters were studied in healthy volunteers." | 5.05 | Stimulation of dopamine receptors (type 2) lowers human intraocular pressure. ( Mekki, QA; Turner, P, 1985) |
| "Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits." | 3.70 | Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998) |
| "The dopamine (DA2) receptor agonist 2,10,11-trihydroxy-N-n-propylnoraporphine (TNPA) was tested for effects on 1) intraocular pressure (IOP), 2) aqueous humor flow rate, 3) electrically induced contractions of the cat nictitating membrane, 4) 3H-NE release from isolated rabbit iris-ciliary bodies and 5) cAMP accumulation in the isolated rabbit iris-ciliary body." | 3.68 | Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine. ( Chu, TC; Ogidigben, M; Potter, DE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Potter, DE | 5 |
| Burke, JA | 2 |
| Chang, FW | 1 |
| Ogidigben, M | 1 |
| Chu, TC | 2 |
| Ogidigben, MJ | 3 |
| Heath, AR | 1 |
| Liao, SL | 1 |
| Hung, PT | 1 |
| Chen, YC | 1 |
| Lan, WL | 1 |
| Mekki, QA | 2 |
| Turner, P | 2 |
2 trials available for metoclopramide and Intraocular Pressure
| Article | Year |
|---|---|
Safety and ocular hypotensive efficacy of a single dose of metoclopramide or droperidol in healthy subjects.
Topics: Adult; Dopamine Antagonists; Droperidol; Female; Humans; Intraocular Pressure; Male; Metoclopramide | 1999 |
Stimulation of dopamine receptors (type 2) lowers human intraocular pressure.
Topics: Bromocriptine; Drug Interactions; Humans; Intraocular Pressure; Male; Metoclopramide; Prolactin; Pup | 1985 |
6 other studies available for metoclopramide and Intraocular Pressure
| Article | Year |
|---|---|
Alteration in ocular function induced by phenylethylamine analogs of dopamine.
Topics: Animals; Blinking; Blood Pressure; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Int | 1984 |
Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine.
Topics: Animals; Aporphines; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Dopamine Agents; Drug Interactio | 1993 |
Ocular actions of an octahydrobenzo[f]quinoline: Ha117.
Topics: Animals; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Domperidone; Dopamine Agents; Electric Stimu | 1993 |
Lisuride acts at multiple sites to induce ocular hypotension and mydriasis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Ocular inhibitory effects of the dopamine DA2 agonist (Ha-118) in cats and rabbits.
Topics: Animals; Cats; Dopamine Agents; Electric Stimulation; Female; In Vitro Techniques; Intraocular Press | 1990 |
Dopamine-2 receptor blockade does not affect the ocular hypotensive action of timolol.
Topics: Adult; Female; Humans; Intraocular Pressure; Male; Metoclopramide; Receptors, Dopamine; Time Factors | 1988 |