Page last updated: 2024-10-31

metoclopramide and Intestinal Pseudo-Obstruction

metoclopramide has been researched along with Intestinal Pseudo-Obstruction in 11 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Intestinal Pseudo-Obstruction: A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.

Research Excerpts

ExcerptRelevanceReference
"Metoclopramide or placebo was administered postoperatively in a randomized, double-blind fashion to 115 patients undergoing laparotomy."2.65The effects of metoclopramide on postoperative ileus. A randomized double-blind study. ( Barnett, SM; Boyle, LP; Brinner, RA; Davidson, ED; Hersh, T, 1979)
"Magnesium deficiency was present in seven patients and its correction resulted in amelioration of the symptom complex."1.26Chronic intestinal pseudo-obstruction. ( Brandenburg, D; Brooks, WS; Hersh, T; Hirsh, EH, 1981)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oh, CH1
Ji, GY1
Yoon, SH1
Hyun, D1
Park, HC1
Kim, YJ1
Lykkegaard-Nielsen, M1
Madsen, PV1
Nielsen, OV1
Shangaĭ, VA1
Lebedinets, VN1
Weihrauch, TR1
Kilbinger, H1
Hirsh, EH1
Brandenburg, D1
Hersh, T2
Brooks, WS1
Saito, T1
Miyai, I1
Matsumura, T1
Nozaki, S1
Kang, J1
Yoshida, K1
Tatsukawa, H1
Ashida, K1
Matsubara, K1
Kubota, Y1
Uwatoko, H1
Ogasawara, H1
Katsuma, Y1
Kitamura, K1
Davidson, ED1
Brinner, RA1
Barnett, SM1
Boyle, LP1
Riabrsev, VG1
Iarema, IV1
Dzheĭranov, FD1
Mezvrishvili, GO1
Fil'chev, MI1
Layer, P1
Goebell, H1
Ricci, DA1
McCallum, RW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery[NCT02056405]Phase 490 participants (Anticipated)Interventional2015-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for metoclopramide and Intestinal Pseudo-Obstruction

ArticleYear
[Motility-effective drugs for therapy of gastrointestinal functional disorders].
    Deutsche medizinische Wochenschrift (1946), 1982, Sep-03, Volume: 107, Issue:35

    Topics: Bethanechol Compounds; Carbachol; Domperidone; Esophagitis, Peptic; Gastrointestinal Diseases; Gastr

1982
Diagnosis and treatment of delayed gastric emptying.
    Advances in internal medicine, 1988, Volume: 33

    Topics: Anemia, Pernicious; Anorexia Nervosa; Cisapride; Connective Tissue Diseases; Diabetes Complications;

1988

Trials

2 trials available for metoclopramide and Intestinal Pseudo-Obstruction

ArticleYear
Ceruletide vs. metoclopramide in postoperative intestinal paralysis. A double-blind clinical trial.
    Diseases of the colon and rectum, 1984, Volume: 27, Issue:5

    Topics: Adult; Aged; Ceruletide; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Intestinal O

1984
The effects of metoclopramide on postoperative ileus. A randomized double-blind study.
    Annals of surgery, 1979, Volume: 190, Issue:1

    Topics: Adult; Aged; Digestive System Surgical Procedures; Female; Gastrointestinal Motility; Humans; Intest

1979

Other Studies

7 other studies available for metoclopramide and Intestinal Pseudo-Obstruction

ArticleYear
Paralytic Ileus and Prophylactic Gastrointestinal Motility Medication after Spinal Operation.
    Yonsei medical journal, 2015, Volume: 56, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Aged; Antiemetics; Female; Gastrointestinal Motility; Humans; Injectio

2015
[Pharmacological regulation of intestinal motility in patients with injuries].
    Ortopediia travmatologiia i protezirovanie, 1984, Issue:2

    Topics: Adolescent; Adult; Gastrointestinal Motility; Humans; Intestinal Obstruction; Intestinal Pseudo-Obst

1984
Chronic intestinal pseudo-obstruction.
    Journal of clinical gastroenterology, 1981, Volume: 3, Issue:3

    Topics: Adult; Aged; Celiac Disease; Chronic Disease; Female; Humans; Intestinal Obstruction; Intestinal Pse

1981
[A case of myotonic dystrophy with intestinal pseudo-obstruction syndrome].
    Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:10

    Topics: Acetylcholine; Adult; Antiemetics; Autonomic Nervous System Diseases; Fasting; Humans; Infusions, In

1999
[Pheochromocytoma with severe paralytic ileus occurred from acute pulmonary edema caused by metoclopramide].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Aug-10, Volume: 90, Issue:8

    Topics: Adrenal Gland Neoplasms; Adult; Antiemetics; Female; Humans; Intestinal Pseudo-Obstruction; Metoclop

2001
[Hemosorption and endolymphatic therapy in the treatment of paralytic ileus in peritonitis and acute intestinal obstruction].
    Vestnik khirurgii imeni I. I. Grekova, 1990, Volume: 144, Issue:3

    Topics: Acute Disease; Aged; Female; Gastrointestinal Motility; Hemoperfusion; Humans; Injections, Intralymp

1990
[Therapy of motility disorders of the stomach and small intestine].
    Deutsche medizinische Wochenschrift (1946), 1991, Feb-22, Volume: 116, Issue:8

    Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal

1991