Page last updated: 2024-10-31

metoclopramide and Intestinal Diseases

metoclopramide has been researched along with Intestinal Diseases in 14 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin treatment markedly enhanced inducible nitric oxide synthase and chemokine mRNA expression in the small intestine, but these responses were all significantly attenuated by either domperidone or metoclopramide."5.37Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. ( Amagase, K; Hashimura, H; Iimori, M; Kato, S; Kawahara, R; Takeuchi, K; Yamanaka, N; Yasuda, M, 2011)
"Metoclopramide is known to enhance gastric emptying and stimulate duodenal and small-intestinal peristaltic activity."2.64The role of metoclopramide in peroral jejunal biopsy: a controlled randomized trial. ( Arvanitakis, C; Gonzalez, G; Rhodes, JB, 1976)
"Indomethacin treatment markedly enhanced inducible nitric oxide synthase and chemokine mRNA expression in the small intestine, but these responses were all significantly attenuated by either domperidone or metoclopramide."1.37Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. ( Amagase, K; Hashimura, H; Iimori, M; Kato, S; Kawahara, R; Takeuchi, K; Yamanaka, N; Yasuda, M, 2011)
"Metoclopramide was not administered to the first 83 patients (Group 1) but was given orally (10 mg) to the subsequent 67 (Group 2)."1.33Complete small-bowel transit in patients undergoing capsule endoscopy: determining factors and improvement with metoclopramide. ( Selby, W, 2005)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Postgate, A1
Tekkis, P1
Patterson, N1
Fitzpatrick, A1
Bassett, P1
Fraser, C1
Carachi, R1
Currie, JM1
Steven, M1
Shiotani, A1
Honda, K1
Kawakami, M1
Nishi, R1
Murao, T1
Ishii, M1
Matsumoto, H1
Kusunoki, H1
Hata, J1
Haruma, K1
Hosono, K1
Endo, H1
Sakai, E1
Sekino, Y1
Uchiyama, T1
Watanabe, S1
Iida, H1
Sakamoto, Y1
Koide, T1
Takahashi, H1
Yoneda, M1
Tokoro, C1
Abe, Y1
Inamori, M1
Kobayashi, N1
Kubota, K1
Nakajima, A1
Yasuda, M1
Kawahara, R1
Hashimura, H1
Yamanaka, N1
Iimori, M1
Amagase, K1
Kato, S1
Takeuchi, K1
Selby, W1
Hansen, W1
Lux, G1
Rösch, W1
Heeres, JP1
Arvanitakis, C1
Gonzalez, G1
Rhodes, JB1
Layer, P1
Goebell, H1
Reynolds, JC1
Bernstein, G1
Rifkin, H1
Stellamor, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Sham Feeding on Small Bowel Transit Time in Patients Undergoing Capsule Endoscopy: a Prospective Randomized Trial[NCT02353208]122 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metoclopramide and Intestinal Diseases

ArticleYear
New tools in the treatment of motility disorders in children.
    Seminars in pediatric surgery, 2009, Volume: 18, Issue:4

    Topics: Autonomic Nerve Block; Celiac Plexus; Child; Child, Preschool; Dopamine Antagonists; Gastrointestina

2009
[Dietary and drug therapy of intestinal disease].
    Medizinische Klinik, 1980, Jun-06, Volume: 75, Issue:12

    Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative;

1980
Prokinetic agents: a key in the future of gastroenterology.
    Gastroenterology clinics of North America, 1989, Volume: 18, Issue:2

    Topics: Biomechanical Phenomena; Cisapride; Domperidone; Forecasting; Gastroenterology; Gastroesophageal Ref

1989

Trials

4 trials available for metoclopramide and Intestinal Diseases

ArticleYear
Are bowel purgatives and prokinetics useful for small-bowel capsule endoscopy? A prospective randomized controlled study.
    Gastrointestinal endoscopy, 2009, Volume: 69, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Capsule Endoscopy; Cathartics; Citric Acid; Drug Adminis

2009
Optimal approach for small bowel capsule endoscopy using polyethylene glycol and metoclopramide with the assistance of a real-time viewer.
    Digestion, 2011, Volume: 84, Issue:2

    Topics: Adult; Aged; Capsule Endoscopy; Chi-Square Distribution; Female; Gastric Emptying; Gastrointestinal

2011
[Double-blind comparison of the efficacy of librax versus primperan with gastrointestinal troubles (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Jul-11, Volume: 67, Issue:28

    Topics: Chlordiazepoxide; Drug Combinations; Humans; Intestinal Diseases; Metoclopramide; Quinuclidines

1978
The role of metoclopramide in peroral jejunal biopsy: a controlled randomized trial.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Aged; Biopsy; Female; Fluoroscopy; Humans; Intestinal Diseases; Intubation, Gastr

1976

Other Studies

7 other studies available for metoclopramide and Intestinal Diseases

ArticleYear
Use of an external real-time image viewer coupled with prespecified actions enhanced the complete examinations for capsule endoscopy.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Capsule Endoscopy; Case-Control Studies; Chi-Square Distribution; Co

2011
Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors.
    Journal of pharmacological sciences, 2011, Volume: 116, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce

2011
Complete small-bowel transit in patients undergoing capsule endoscopy: determining factors and improvement with metoclopramide.
    Gastrointestinal endoscopy, 2005, Volume: 61, Issue:1

    Topics: Aged; Dopamine Antagonists; Electric Power Supplies; Endoscopy, Gastrointestinal; Equipment Design;

2005
[Drug therapy of gastrointestinal motility disorders].
    Fortschritte der Medizin, 1980, Aug-21, Volume: 98, Issue:30-31

    Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Du

1980
[Therapy of motility disorders of the stomach and small intestine].
    Deutsche medizinische Wochenschrift (1946), 1991, Feb-22, Volume: 116, Issue:8

    Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal

1991
Diabetes mellitus: gastrointestinal complications.
    Comprehensive therapy, 1986, Volume: 12, Issue:11

    Topics: Blood Glucose; Cholecystitis; Cholelithiasis; Diabetes Complications; Diabetic Neuropathies; Esophag

1986
[A new possibility for routine x-ray examination of the small intestine].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:7

    Topics: Achlorhydria; Biliary Tract Diseases; Colonic Diseases; Contrast Media; Gastrointestinal Motility; H

1973