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metoclopramide and Intellectual Disability

metoclopramide has been researched along with Intellectual Disability in 4 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine."7.68Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991)
"We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine."3.68Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991)
"Plasma levels of beta-endorphin (beta-EP) and prolactin (PRL) were measured in 5 girls with Rett syndrome and in a control group before and after giving 10 mg metoclopramide i."3.67Plasma endorphins in Rett syndrome: preliminary data. ( Bernasconi, S; Facchinetti, F; Genazzani, AR; Nalin, A; Petraglia, F; Zappella, M, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Archer, T1
Factor, SA1
Matthews, MK1
Russell, JE1
Gedye, A1
Facchinetti, F1
Zappella, M1
Nalin, A1
Petraglia, F1
Bernasconi, S1
Genazzani, AR1

Other Studies

4 other studies available for metoclopramide and Intellectual Disability

ArticleYear
Behavioural retardation in the neuropathology of mental retardation.
    APMIS. Supplementum, 1993, Volume: 40

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dihydroxyphenylalanine; Dopamine Agents; Female; Ha

1993
Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy.
    Southern medical journal, 1991, Volume: 84, Issue:5

    Topics: Basal Ganglia Diseases; Cerebral Palsy; Dystonia; Female; Humans; Intellectual Disability; Metoclopr

1991
Self-injury, regurgitation, and antiemetics.
    Lancet (London, England), 1989, Jan-28, Volume: 1, Issue:8631

    Topics: Adult; Domperidone; Down Syndrome; Gastroesophageal Reflux; Humans; Intellectual Disability; Male; M

1989
Plasma endorphins in Rett syndrome: preliminary data.
    American journal of medical genetics. Supplement, 1986, Volume: 1

    Topics: Adolescent; beta-Endorphin; beta-Lipotropin; Child; Child, Preschool; Endorphins; Female; Humans; In

1986