metoclopramide has been researched along with Idiopathic Parkinson Disease in 22 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of prolonged encephalopathy and worsened parkinsonism in a Parkinson disease patient exposed to a short course of metoclopramide is described." | 7.76 | Metoclopramide-induced encephalopathy in Parkinson disease. ( Anderson, KE; Robottom, BJ; Shulman, LM; Weiner, WJ, 2010) |
| " Although known to interfere with central dopamine mechanisms, it is frequently used in Parkinson's disease to prevent levodopa-induced nausea and vomiting." | 5.04 | Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975) |
| "A case of prolonged encephalopathy and worsened parkinsonism in a Parkinson disease patient exposed to a short course of metoclopramide is described." | 3.76 | Metoclopramide-induced encephalopathy in Parkinson disease. ( Anderson, KE; Robottom, BJ; Shulman, LM; Weiner, WJ, 2010) |
| "5." | 2.64 | Plasma bromocriptine levels, clinical and growth hormone responses in Parkinsonism. ( Debono, A; Marsden, CD; Parkes, JD; Price, P; Rosenthaler, J, 1978) |
| "The case of a patient with Parkinson's disease (PD) who experienced profound encephalopathy after short-term exposure to metoclopramide is described." | 1.38 | Encephalopathy associated with metoclopramide use in a patient with Parkinson's disease. ( Johnson, BR; Khan, MA; Messerschmidt, KA, 2012) |
| "Metoclopramide 60 mg oral was given 30 minutes before bromocriptine or levodopa to establish whether this caused dopamine-receptor blockade." | 1.26 | Bromocriptine in Parkinsonism: long-term treatment, dose response, and comparison with levodopa. ( Debono, AG; Marsden, CD; Parkes, JD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robottom, BJ | 1 |
| Shulman, LM | 1 |
| Anderson, KE | 1 |
| Weiner, WJ | 1 |
| Messerschmidt, KA | 1 |
| Johnson, BR | 1 |
| Khan, MA | 1 |
| Campbell, DJ | 1 |
| Mendelsohn, FA | 1 |
| Adam, WR | 1 |
| Funder, JW | 1 |
| Schachter, M | 1 |
| Bédard, P | 1 |
| Debono, AG | 2 |
| Jenner, P | 3 |
| Marsden, CD | 7 |
| Price, P | 2 |
| Parkes, JD | 5 |
| Keenan, J | 1 |
| Smith, B | 1 |
| Rosenthaler, J | 2 |
| Horowski, R | 1 |
| Dorow, R | 1 |
| Mateos, V | 1 |
| Caminal, L | 1 |
| Colosía, VP | 1 |
| Campos, DM | 1 |
| Negoro, K | 1 |
| Morimatsu, M | 1 |
| Nogaki, H | 1 |
| Tarsy, D | 3 |
| Peringer, E | 1 |
| Bateman, DN | 1 |
| Kahn, C | 1 |
| Legg, NJ | 1 |
| Reid, JL | 1 |
| Debono, A | 1 |
| Rampton, DS | 1 |
| Dolphin, A | 1 |
| Pycock, C | 1 |
| Holmsen, R | 1 |
| Corsini, GU | 1 |
| Zompo, MD | 1 |
| Cianchetti, C | 1 |
| Mangoni, A | 1 |
| Laihinen, A | 1 |
| Rinne, UK | 1 |
| Shaughnessy, AF | 1 |
| Carter, AB | 1 |
| Mearrick, PT | 1 |
| Wade, DN | 1 |
| Birkett, DJ | 1 |
| Morris, J | 1 |
2 reviews available for metoclopramide and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Is aldosterone secretion under dopaminergic control?
Topics: Aldosterone; Bromocriptine; Chlorpromazine; Dopamine; Dopamine Antagonists; Edema; Humans; Levodopa; | 1981 |
Potential uses for metoclopramide.
Topics: Anorexia Nervosa; Bezoars; Dyskinesia, Drug-Induced; Failure to Thrive; Hiccup; Humans; Metocloprami | 1985 |
4 trials available for metoclopramide and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Letter: Metoclopramide in parkinsonism.
Topics: Clinical Trials as Topic; Humans; Levodopa; Metoclopramide; Nausea; Parkinson Disease; Promethazine; | 1975 |
Metoclopramide in Parkinson's disease.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Metoclopramide; Middle | 1978 |
Plasma bromocriptine levels, clinical and growth hormone responses in Parkinsonism.
Topics: Aged; Blood Pressure; Bromocriptine; Clinical Trials as Topic; Female; Growth Hormone; Humans; Male; | 1978 |
Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combina | 1975 |
16 other studies available for metoclopramide and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Metoclopramide-induced encephalopathy in Parkinson disease.
Topics: Aged; Antiemetics; Constipation; Humans; Male; Metoclopramide; Neurotoxicity Syndromes; Parkinson Di | 2010 |
Encephalopathy associated with metoclopramide use in a patient with Parkinson's disease.
Topics: Aged; Brain Diseases, Metabolic; Humans; Male; Metoclopramide; Parkinson Disease | 2012 |
Not Parkinson's disease.
Topics: Adult; Aged; Antipsychotic Agents; Diagnosis, Differential; Humans; Metoclopramide; Middle Aged; Par | 1982 |
The role of D-1 and D-2 receptors.
Topics: Adenylyl Cyclases; Bromocriptine; Growth Hormone; Humans; Levodopa; Lisuride; Metoclopramide; Parkin | 1980 |
[Parkinsonism induced by metoclopramide].
Topics: Female; Humans; Metoclopramide; Middle Aged; Parkinson Disease | 1993 |
Drug-induced dystonia and dysphonia in Parkinson's disease.
Topics: Dopamine Antagonists; Dystonia; Humans; Metoclopramide; Parkinson Disease; Voice Disorders | 1999 |
Effect of metoclopramide on turnover of brain dopamine noradrenaline and 5-hydroxytryptamine.
Topics: Animals; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homova | 1975 |
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline.
Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Human | 1977 |
Bromocriptine in Parkinsonism: long-term treatment, dose response, and comparison with levodopa.
Topics: Aged; Bromocriptine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; D | 1976 |
Pharmacological evidence for cerebral dopamine receptor blockade by metoclopramide in rodents.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Humans; Male; Met | 1975 |
[L-dopa-decarboxylase inhibitor combination preparation (Sinemet) in parkinsonism and syndromes imitating parkinsonism. 1 year's experience with 34 patients].
Topics: Aged; Drug Combinations; Female; Humans; Levodopa; Male; Metoclopramide; Middle Aged; Nausea; Parkin | 1976 |
Therapeutical efficacy of a combination of apomorphine with sulpiride or metoclopramide in Parkinsonism.
Topics: Adult; Apomorphine; Drug Therapy, Combination; Haloperidol; Humans; Male; Metoclopramide; Parkinson | 1976 |
Dopamine receptor function in Parkinson's disease--in vivo studies with prolactin responses.
Topics: Bromocriptine; Corpus Striatum; Humans; Metoclopramide; Parkinson Disease; Prolactin; Receptors, Dop | 1987 |
Letter: Pyridoxine contraindicated in parkinsonism.
Topics: Dihydroxyphenylalanine; Drug Antagonism; Humans; Metoclopramide; Nausea; Parkinson Disease; Pyridoxi | 1973 |
Letter: Pyridoxine in parkinsonism.
Topics: Dihydroxyphenylalanine; Drug Antagonism; Drug Interactions; Humans; Metoclopramide; Movement Disorde | 1973 |
Metoclopramide, gastric emptying and L-dopa absorption.
Topics: Biological Transport, Active; Biopharmaceutics; Female; Fluorometry; Gastrointestinal Motility; Huma | 1974 |