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metoclopramide and Hypotension

metoclopramide has been researched along with Hypotension in 14 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"To report a case of sustained hypotension associated with the use of intravenous metoclopramide."7.79Sustained hypotension following intravenous metoclopramide. ( Nguyen, TT; Petzel Gimbar, RM, 2013)
"Metoclopramide was ineffective."6.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)
"Phenylephrine 100 mug and ephedrine 6 mg had similar efficacy in the treatment of maternal hypotension during spinal anaesthesia for elective caesarean delivery."5.14Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine during spinal anaesthesia for caesarean delivery: a randomised study. ( Chellani, H; Gogia, AR; Prakash, S; Pramanik, V; Salhan, S, 2010)
" One of these agents, batanopride, produced no severe toxicity at doses that prevented emesis due to chemotherapy in early Phase I trials."5.07A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy. ( Findlay, B; Kaizer, L; Laberge, F; Latreille, J; Lofters, WS; Osoba, D; Pater, J; Rusthoven, J; Warr, D; Wilson, K, 1991)
"To report a case of sustained hypotension associated with the use of intravenous metoclopramide."3.79Sustained hypotension following intravenous metoclopramide. ( Nguyen, TT; Petzel Gimbar, RM, 2013)
"To assess the role of spinal dopamine receptors in mediation of hypotension induced by systemic administration of the dopamine D2 receptor agonist, bromocriptine, conscious deoxycorticosterone acetate (DOCA)-salt hypertensive rats were pretreated with either intravenous (i."3.70Hypotensive action of bromocriptine in the DOCA-salt hypertensive rat: contribution of spinal dopamine receptors. ( Duarte, GP; Lahlou, S, 1998)
"Metoclopramide was ineffective."2.68The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. ( Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM, 1995)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's6 (42.86)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nguyen, TT1
Petzel Gimbar, RM1
Prakash, S1
Pramanik, V1
Chellani, H1
Salhan, S1
Gogia, AR1
Lahlou, S3
Hughes, RL1
Pegg, MS1
Park, GR1
Desilva, PH1
Darvish, AH1
McDonald, SM1
Cronin, MK1
Clark, K1
Kafle, SK1
Duarte, GP1
Rusthoven, J1
Pater, J1
Kaizer, L1
Wilson, K1
Osoba, D1
Latreille, J1
Findlay, B1
Lofters, WS1
Warr, D1
Laberge, F1
Herrstedt, J1
Jeppesen, BH1
Dombernowsky, P1
Newman, B1
Lam, AM1
Takabatake, T1
Kawabata, M1
Ohta, H1
Yamamoto, Y1
Ishida, Y1
Hara, H1
Hattori, N1

Trials

5 trials available for metoclopramide and Hypotension

ArticleYear
Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine during spinal anaesthesia for caesarean delivery: a randomised study.
    International journal of obstetric anesthesia, 2010, Volume: 19, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Ulcer Agents; Antiem

2010
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension

1995
Intrathecal meperidine for elective caesarean section: a comparison with lidocaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:8

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Apgar Score; Cesarean Section; Female; Humans;

1993
A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:9

    Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Diarrhea; Dose-Response Relationship, Drug; D

1991
Dose-limiting hypotension with the 5-HT3-antagonist batanopride (BMY-25801).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:2

    Topics: Adult; Aged; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography

1991

Other Studies

9 other studies available for metoclopramide and Hypotension

ArticleYear
Sustained hypotension following intravenous metoclopramide.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:11

    Topics: Dopamine Antagonists; Female; Humans; Hypotension; Metoclopramide; Middle Aged; Migraine Disorders;

2013
Enhanced hypotensive response to intravenous apomorphine in chronic spinalized, conscious rats: role of spinal dopamine D(1) and D(2) receptors.
    Neuroscience letters, 2003, Oct-02, Volume: 349, Issue:2

    Topics: Animals; Apomorphine; Benzazepines; Blood Pressure; Consciousness; Domperidone; Dopamine Agonists; D

2003
Hypotension and dysrhythmia following intravenous metoclopramide.
    Anaesthesia, 1984, Volume: 39, Issue:7

    Topics: Adult; Arrhythmias, Cardiac; Female; Humans; Hypotension; Intraoperative Complications; Metocloprami

1984
Hypotension following metoclopramide injection.
    Anaesthesia, 1980, Volume: 35, Issue:6

    Topics: Humans; Hypotension; Metoclopramide; Neurosurgical Procedures

1980
Hypotension following the intravenous injection of metoclopramide.
    Anaesthesia, 1981, Volume: 36, Issue:1

    Topics: Humans; Hypotension; Metoclopramide

1981
Involvement of spinal dopamine receptors in mediation of the hypotensive and bradycardic effects of systemic quinpirole in anaesthetised rats.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Animals; Bradycardia; Domperidone; Dopamine Agonists; Dose-Response Relationship, Drug; Hypotension;

1998
Hypotensive action of bromocriptine in the DOCA-salt hypertensive rat: contribution of spinal dopamine receptors.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bromocriptine; Desoxycorticosterone;

1998
Induced hypotension for clipping of a cerebral aneurysm during pregnancy: a case report and brief review.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Blood Pressure; Cimetidine; Female; Fetal Monitoring; Humans; Hypoten

1986
Acute renal failure and transient, massive proteinuria in a case of pheochromocytoma.
    Clinical nephrology, 1985, Volume: 24, Issue:1

    Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Adult; Female; Humans; Hypotension; Kidney; Metoclopra

1985