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metoclopramide and Hypogonadism

metoclopramide has been researched along with Hypogonadism in 12 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hypogonadism were studied."7.67The metoclopramide test: a useful tool with the luteinizing hormone-releasing hormone test in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism. ( Avendano, E; Chique, G; Lanes, R; Moncada, G; Palacios, A, 1989)
"The secretion of prolactin (PRL) after intravenous metoclopramide was evaluated in six prepubertal subjects with idiopathic isolated hypogonadotropic hypogonadism before and after repeated testosterone (T) injections."7.67Metoclopramide-mediated prolactin secretion in patients with idiopathic hypogonadotropic hypogonadism: effect of testosterone therapy. ( Modebe, O, 1989)
"The responses of serum prolactin (Prl) to metoclopramide and LH and FSH to GnRH were studied simultaneously in 9 boys with hypogonadotrophic hypogonadism (HH), 7 boys with constitutional delay of puberty (D) and 15 controls."7.67Metoclopramide test in the diagnosis of isolated hypogonadotrophic hypogonadism. ( Dunkel, L, 1986)
"The prolactin response to metoclopramide (MCP) was studied in 23 sexually immature males, 14 with isolated hypogonadotrophic hypogonadism (IHH) and nine with constitutional delayed puberty."7.67Prolactin response to metoclopramide does not distinguish patients with hypogonadotrophic hypogonadism from delayed puberty. ( Cassorla, F; Cristiano, AM; el Sabbagh, H; Munabi, A; Sherins, RJ, 1988)
"The patients with microprolactinomas had a low prolactin response (increments less than 300-400%) and delayed TSH response."5.28[Pharmacodynamic metoclopramide (cerucal) test in differential diagnosis of hypoprolactinemic hypogonadism syndrome in women]. ( Balabolkin, MI; Gerasimov, GA; Liubimov, AV, 1990)
"To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hypogonadism were studied."3.67The metoclopramide test: a useful tool with the luteinizing hormone-releasing hormone test in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism. ( Avendano, E; Chique, G; Lanes, R; Moncada, G; Palacios, A, 1989)
"The secretion of prolactin (PRL) after intravenous metoclopramide was evaluated in six prepubertal subjects with idiopathic isolated hypogonadotropic hypogonadism before and after repeated testosterone (T) injections."3.67Metoclopramide-mediated prolactin secretion in patients with idiopathic hypogonadotropic hypogonadism: effect of testosterone therapy. ( Modebe, O, 1989)
"The responses of serum prolactin (Prl) to metoclopramide and LH and FSH to GnRH were studied simultaneously in 9 boys with hypogonadotrophic hypogonadism (HH), 7 boys with constitutional delay of puberty (D) and 15 controls."3.67Metoclopramide test in the diagnosis of isolated hypogonadotrophic hypogonadism. ( Dunkel, L, 1986)
"The prolactin response to metoclopramide (MCP) was studied in 23 sexually immature males, 14 with isolated hypogonadotrophic hypogonadism (IHH) and nine with constitutional delayed puberty."3.67Prolactin response to metoclopramide does not distinguish patients with hypogonadotrophic hypogonadism from delayed puberty. ( Cassorla, F; Cristiano, AM; el Sabbagh, H; Munabi, A; Sherins, RJ, 1988)
"The functional activity of endogenous opioids and dopamine (DA) was assessed by analyzing gonadotropin and prolactin responses to DA receptor antagonist (metoclopramide) and the opioid receptor antagonist (naloxone) in selected patients with hypothalamic hypogonadotropic amenorrhea and in normal cycling women."3.66Evidence for increased dopaminergic and opioid activity in patients with hypothalamic hypogonadotropic amenorrhea. ( Casper, RF; Quigley, ME; Sheehan, KL; Yen, SS, 1980)
"The patients with microprolactinomas had a low prolactin response (increments less than 300-400%) and delayed TSH response."1.28[Pharmacodynamic metoclopramide (cerucal) test in differential diagnosis of hypoprolactinemic hypogonadism syndrome in women]. ( Balabolkin, MI; Gerasimov, GA; Liubimov, AV, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quigley, ME1
Sheehan, KL1
Casper, RF1
Yen, SS1
Spitz, IM1
Zylber-Haran, EA1
Trestian, S1
Dickstein, Y1
Palti, Z1
Schenker, JG1
Kannan, V1
Vijaya, G1
Verhelst, J1
Beckers, A1
Abs, R1
Cohen, HN2
Hay, ID2
Beastall, GH2
Thomson, JA2
Auchterlonie, IA1
Balabolkin, MI1
Gerasimov, GA1
Liubimov, AV1
Lanes, R1
Palacios, A1
Avendano, E1
Moncada, G1
Chique, G1
Modebe, O1
Dunkel, L2
Huhtaniemi, I1
Cristiano, AM1
Munabi, A1
el Sabbagh, H1
Cassorla, F1
Sherins, RJ1

Other Studies

12 other studies available for metoclopramide and Hypogonadism

ArticleYear
Evidence for increased dopaminergic and opioid activity in patients with hypothalamic hypogonadotropic amenorrhea.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:5

    Topics: Adult; Amenorrhea; Dopamine; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hypogonadism;

1980
The decreased basal and stimulated prolactin levels in isolated gonadotrophin deficiency: a consequence of the low oestrogen state.
    Clinical endocrinology, 1982, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Chorionic Gonadotropin; Clomiphene; Estradiol; Estrogens, Conjugated (USP); Ethin

1982
Endocrine testicular functions in leprosy.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:3

    Topics: Adult; Chorionic Gonadotropin; Estradiol; Follicle Stimulating Hormone; Hormones; Humans; Hypogonadi

1984
The effect of naloxone and metoclopramide on the secretion of luteinizing hormone in a hyperprolactinemic hypogonadotropic postmenopausal woman.
    Fertility and sterility, 1995, Volume: 64, Issue:5

    Topics: Aged; Bromocriptine; Dopamine Agonists; Dopamine Antagonists; Female; Follicle Stimulating Hormone;

1995
Metoclopramide induced growth hormone release in hypogonadal males.
    Clinical endocrinology, 1979, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Growth Hormone; Humans; Hypogonadism; Kinetics; Male; Metoclopramide; Testis

1979
Growth hormone response to metoclopramide [proceedings].
    The Journal of endocrinology, 1979, Volume: 83, Issue:1

    Topics: Adolescent; Adult; Child; Female; Growth Hormone; Humans; Hypogonadism; Male; Metoclopramide; Pituit

1979
[Pharmacodynamic metoclopramide (cerucal) test in differential diagnosis of hypoprolactinemic hypogonadism syndrome in women].
    Akusherstvo i ginekologiia, 1990, Issue:2

    Topics: Adult; Diagnosis, Differential; Female; Humans; Hyperprolactinemia; Hypogonadism; Metoclopramide; Pi

1990
The metoclopramide test: a useful tool with the luteinizing hormone-releasing hormone test in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism.
    Fertility and sterility, 1989, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Diagnosis, Differential; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; Lu

1989
Metoclopramide-mediated prolactin secretion in patients with idiopathic hypogonadotropic hypogonadism: effect of testosterone therapy.
    Fertility and sterility, 1989, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Humans; Hypogonadism; Male; Metoclopramide; Osmolar Concentration; Prolactin; Tes

1989
Abnormal prolactin secretion in prepubertal boys with hypogonadotrophic hypogonadism--possible involvement in regulation of testicular steroidogenesis.
    International journal of andrology, 1985, Volume: 8, Issue:5

    Topics: Adolescent; Child; Cryptorchidism; Follicle Stimulating Hormone; Follow-Up Studies; Gonadotropin-Rel

1985
Metoclopramide test in the diagnosis of isolated hypogonadotrophic hypogonadism.
    Acta endocrinologica, 1986, Volume: 111, Issue:2

    Topics: Adolescent; Child; Diagnosis, Differential; Follicle Stimulating Hormone; Humans; Hypogonadism; Lute

1986
Prolactin response to metoclopramide does not distinguish patients with hypogonadotrophic hypogonadism from delayed puberty.
    Clinical endocrinology, 1988, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Chlorpromazine; Chorionic Gonadotropin; Diagnosis, Differential; Humans; Hypogona

1988