metoclopramide has been researched along with Heartburn in 20 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Heartburn: Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ranitidine and metoclopramide were compared for their ability to reduce esophageal acid contact time and heartburn." | 9.06 | Esophageal acid contact time and heartburn in acute treatment with ranitidine and metoclopramide. ( Finn, A; Orr, WC; Russell, J; Wilson, T, 1990) |
| "Ten patients with gastroesophageal reflux disease participated in a randomized, double-blind, crossover study in which they received a single 20-mg oral dose of metoclopramide or a placebo 15 minutes before a provocative test meal." | 9.05 | Prevention of meal-induced heartburn and regurgitation with metoclopramide in patients with gastroesophageal reflux. ( Bartolomeo, RS; Fuchs, B, 1982) |
| "Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn." | 9.04 | A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 7.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| "Ranitidine and metoclopramide were compared for their ability to reduce esophageal acid contact time and heartburn." | 5.06 | Esophageal acid contact time and heartburn in acute treatment with ranitidine and metoclopramide. ( Finn, A; Orr, WC; Russell, J; Wilson, T, 1990) |
| "Ten patients with gastroesophageal reflux disease participated in a randomized, double-blind, crossover study in which they received a single 20-mg oral dose of metoclopramide or a placebo 15 minutes before a provocative test meal." | 5.05 | Prevention of meal-induced heartburn and regurgitation with metoclopramide in patients with gastroesophageal reflux. ( Bartolomeo, RS; Fuchs, B, 1982) |
| "Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn." | 5.04 | A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 3.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| "Heartburn is a normal consequence of pregnancy." | 2.43 | Review article: the management of heartburn in pregnancy. ( Richter, JE, 2005) |
| "Gastroesophageal reflux (GER) disease is a common, multifactorial medical condition that may be difficult to treat." | 1.27 | A critical review of current medical therapy for gastroesophageal reflux disease. ( Richter, JE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richter, JE | 2 |
| Wu, WC | 1 |
| Castell, DO | 1 |
| McCallum, RW | 2 |
| Fink, SM | 1 |
| Winnan, GR | 1 |
| Avella, J | 1 |
| Callachan, C | 1 |
| Fuchs, B | 1 |
| Bartolomeo, RS | 1 |
| Robinson, M | 1 |
| Decktor, DL | 1 |
| Maton, PN | 1 |
| Sabesin, S | 1 |
| Roufail, W | 1 |
| Kogut, D | 1 |
| Roberts, W | 1 |
| McCullough, A | 1 |
| Pardoll, P | 1 |
| Saco, L | 1 |
| Clearfield, HR | 1 |
| Hollander, D | 1 |
| Karris, G | 1 |
| Ippoliti, AF | 1 |
| Cooney, C | 1 |
| Sturdevant, RA | 1 |
| Hey, VM | 1 |
| Ostick, DG | 1 |
| Roufail, WM | 1 |
| Brock-Utne, JG | 1 |
| Dow, TG | 1 |
| Welman, S | 1 |
| Dimopoulos, GE | 1 |
| Moshal, MG | 1 |
| Behar, J | 1 |
| Orr, WC | 1 |
| Finn, A | 1 |
| Wilson, T | 1 |
| Russell, J | 1 |
| Howden, CW | 1 |
| Saad Zoi, R | 1 |
| Johnson, AG | 1 |
| Venables, CW | 1 |
| Bell, D | 1 |
| Eccleston, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy of Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy : A Randomized Double-Blind Controlled Trial[NCT02470117] | Phase 4 | 100 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for metoclopramide and Heartburn
| Article | Year |
|---|---|
Review article: the management of heartburn in pregnancy.
Topics: Antacids; Anti-Ulcer Agents; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Motility; | 2005 |
Gastroesophageal reflux.
Topics: Antacids; Cimetidine; Esophagogastric Junction; Gastroesophageal Reflux; Heartburn; Humans; Metoclop | 1983 |
Reflux esophagitis: pathogenesis, diagnosis, and management.
Topics: Antacids; Biopsy; Esophagitis, Peptic; Esophagogastric Junction; Esophagoscopy; Gastrins; Heartburn; | 1976 |
8 trials available for metoclopramide and Heartburn
| Article | Year |
|---|---|
Metoclopramide in gastroesophageal reflux disease: rationale for its use and results of a double-blind trial.
Topics: Adult; Aged; Antacids; Clinical Trials as Topic; Double-Blind Method; Gastric Emptying; Gastroesopha | 1984 |
Prevention of meal-induced heartburn and regurgitation with metoclopramide in patients with gastroesophageal reflux.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Food; Gastroesophageal Reflux; Heartbu | 1982 |
Omeprazole is superior to ranitidine plus metoclopramide in the short-term treatment of erosive oesophagitis.
Topics: Adult; Antacids; Circadian Rhythm; Drug Therapy, Combination; Esophagitis, Peptic; Female; Gastroeso | 1993 |
A controlled trial of metoclopramide in symptomatic gastroesophageal reflux.
Topics: Antacids; Anxiety; Chronic Disease; Clinical Trials as Topic; Esophagus; Female; Gastroesophageal Re | 1977 |
Metoclopramide and the gastro-oesophageal sphincter. A study in pregnant women with heartburn.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Esophagogastric Junction; Female; | 1978 |
Esophageal acid contact time and heartburn in acute treatment with ranitidine and metoclopramide.
Topics: Adult; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrogen-Ion Concentration; Ma | 1990 |
Flatulent dyspepsia.
Topics: Clinical Trials as Topic; Dyspepsia; Female; Flatulence; Gastroesophageal Reflux; Heartburn; Humans; | 1973 |
A double-blind study of metoclopramide in symptomatic peptic oesophagitis.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Esophagitis; Female; Gastroesophageal R | 1973 |
9 other studies available for metoclopramide and Heartburn
| Article | Year |
|---|---|
[With evidence-based phytotherapy. Takes away gastric and intestinal irritation].
Topics: Antiemetics; Cisapride; Clinical Trials as Topic; Dopamine Antagonists; Evidence-Based Medicine; Gas | 2003 |
Heartburn.
Topics: Antacids; Bethanechol Compounds; Heartburn; Histamine H2 Antagonists; Humans; Metoclopramide | 1977 |
Efficacy of medical management of gastroesophageal reflux: a critical assessment.
Topics: Alginates; Aluminum Hydroxide; Antacids; Bethanechol Compounds; Bicarbonates; Drug Combinations; Eso | 1978 |
Medical management of patients with reflux esophagitis.
Topics: Alginates; Antacids; Bethanechol Compounds; Cimetidine; Esophagitis, Peptic; Heartburn; Humans; Meto | 1978 |
The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy.
Topics: Adolescent; Adult; Esophagogastric Junction; Female; Gastroesophageal Reflux; Heartburn; Humans; Met | 1978 |
A critical review of current medical therapy for gastroesophageal reflux disease.
Topics: Alginates; Antacids; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Gastroesopha | 1986 |
Treatment of common minor ailments.
Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonist | 1986 |
[Primperan during pregnancy].
Topics: Female; Heartburn; Humans; Metoclopramide; Pneumonia, Aspiration; Pregnancy; Pregnancy Complications | 1985 |
Medical management of heartburn.
Topics: Alginates; Alkalies; Anesthetics, Local; Bethanechol Compounds; Diet; Esophagus; Gastric Acidity Det | 1974 |