metoclopramide has been researched along with Gastroenteritis in 20 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Gastroenteritis: INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy and safety of ondansetron versus less expensive metoclopramide in the treatment of children with persistent vomiting with acute gastroenteritis." | 9.15 | Metoclopramide versus ondansetron for the treatment of vomiting in children with acute gastroenteritis. ( Abdulateef, H; Al-Ansari, K; Alomary, S; Alshawagfa, M; Kamal, K, 2011) |
| "048) with placebo (mean = 5) than ondansetron (mean = 2) and the proportion of patients experiencing no emesis was significantly greater (P = 0." | 9.08 | Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997) |
| "In a double-blind trial in 60 children suffering from gastroenteritis complicated by vomiting, it was found that suppositories of domperidone (30 mg) were more effective than either metoclopramide (10 mg) or placebo in reducing the severity of vomiting, nausea and other symptomatic parameters." | 9.04 | A double-blind comparison of domperidone and metoclopramide suppositories in the treatment of nausea and vomiting in children. ( Ameryckx, L; Dhondt, F; Heck, E; Van Eygen, M; Van Ravensteyn, H, 1979) |
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 7.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| "To compare the efficacy and safety of ondansetron versus less expensive metoclopramide in the treatment of children with persistent vomiting with acute gastroenteritis." | 5.15 | Metoclopramide versus ondansetron for the treatment of vomiting in children with acute gastroenteritis. ( Abdulateef, H; Al-Ansari, K; Alomary, S; Alshawagfa, M; Kamal, K, 2011) |
| "048) with placebo (mean = 5) than ondansetron (mean = 2) and the proportion of patients experiencing no emesis was significantly greater (P = 0." | 5.08 | Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997) |
| " Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0." | 5.05 | Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020) |
| "In a double-blind trial in 60 children suffering from gastroenteritis complicated by vomiting, it was found that suppositories of domperidone (30 mg) were more effective than either metoclopramide (10 mg) or placebo in reducing the severity of vomiting, nausea and other symptomatic parameters." | 5.04 | A double-blind comparison of domperidone and metoclopramide suppositories in the treatment of nausea and vomiting in children. ( Ameryckx, L; Dhondt, F; Heck, E; Van Eygen, M; Van Ravensteyn, H, 1979) |
| "Oral ondansetron increased the proportion of patients who had ceased vomiting and reduced the number needing intravenous rehydration and immediate hospital admission." | 4.87 | Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Carter, B; Fedorowicz, Z; Jagannath, VA, 2011) |
| "The small number of included trials provided some limited evidence favouring the use of ondansetron and metoclopramide over placebo to reduce the number of episodes of vomiting due to gastroenteritis in children." | 4.85 | Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Al-Hashimi, H; Alhashimi, D; Fedorowicz, Z, 2009) |
| "The small number of included trials provided some, albeit weak and unreliable, evidence which appeared to favor the use of ondansetron and metoclopramide over placebo to reduce the number of episodes of vomiting due to gastroenteritis in children." | 4.83 | Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Alhashimi, D; Alhashimi, H; Fedorowicz, Z, 2006) |
| "The small number of included trials provided some, albeit weak and unreliable, evidence which appeared to favor the use of ondansetron and metoclopramide over placebo to reduce the number of episodes of vomiting due to gastroenteritis in children." | 4.83 | Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Alhashimi, D; Alhashimi, H; Fedorowicz, Z, 2006) |
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 3.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| "Two girls, aged 2 and 4 years, with acute gastroenteritis and vomiting, received domperidone and metoclopramide, respectively." | 3.73 | [Urinary retention in 2 children after the use of antiemetic agents during acute gastroenteritis]. ( de Moor, RA; Diemont, WL; van den Bemt, PM; Visser, MO, 2005) |
| " Extrapyramidal side effects like tardive dyskinesia are known to develop with chronic use of metoclopramide, while acute akathisia is a lesser known side effect following IV administration." | 1.37 | Case of acute akathisia from intravenous metoclopramide. ( Lim, BL; Qiu, LM, 2011) |
| "For moderate dehydration, eight CPGs advocated nasogastric (NG) rehydration in preference to intravenous (IV) rehydration." | 1.35 | Emergency department management of gastro-enteritis in Australia and New Zealand. ( Babl, FE; Borland, M; Schutz, J; Sheriff, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niño-Serna, LF | 1 |
| Acosta-Reyes, J | 1 |
| Veroniki, AA | 1 |
| Florez, ID | 1 |
| Dahl, E | 1 |
| Diskin, AL | 1 |
| Schutz, J | 1 |
| Babl, FE | 1 |
| Sheriff, N | 1 |
| Borland, M | 1 |
| Alhashimi, D | 3 |
| Al-Hashimi, H | 1 |
| Fedorowicz, Z | 4 |
| Qiu, LM | 1 |
| Lim, BL | 1 |
| Al-Ansari, K | 1 |
| Alomary, S | 1 |
| Abdulateef, H | 1 |
| Alshawagfa, M | 1 |
| Kamal, K | 1 |
| Jagannath, VA | 1 |
| Carter, B | 1 |
| Cayley, WE | 1 |
| de Moor, RA | 1 |
| Diemont, WL | 1 |
| Visser, MO | 1 |
| van den Bemt, PM | 1 |
| Alhashimi, H | 2 |
| Sciarretta, G | 1 |
| Turba, E | 1 |
| Verri, A | 1 |
| Pinetti, P | 1 |
| Malaguti, P | 1 |
| Carey, MJ | 1 |
| Aitken, ME | 1 |
| Sehgal, N | 1 |
| Cubeddu, LX | 1 |
| Trujillo, LM | 1 |
| Talmaciu, I | 1 |
| Gonzalez, V | 1 |
| Guariguata, J | 1 |
| Seijas, J | 1 |
| Miller, IA | 1 |
| Paska, W | 1 |
| Poorter, ME | 1 |
| Wolf, BH | 1 |
| Woltil, HA | 1 |
| Van Eygen, M | 1 |
| Dhondt, F | 1 |
| Heck, E | 1 |
| Ameryckx, L | 1 |
| Van Ravensteyn, H | 1 |
| Rhodes, JB | 1 |
| Robinson, RG | 1 |
| McBride, N | 1 |
| Heinkelein, J | 1 |
| Ibsen, KK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ondansetron Vs Metoclopramide in the Treatment of Vomiting in Gastroenteritis Patients: A Randomized Controlled Trial[NCT01165866] | Phase 4 | 170 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for metoclopramide and Gastroenteritis
| Article | Year |
|---|---|
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper | 2020 |
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.
Topics: Acute Disease; Adolescent; Antiemetics; Child; Child, Preschool; Gastroenteritis; Humans; Metoclopra | 2009 |
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.
Topics: Acute Disease; Adolescent; Antiemetics; Child; Child, Preschool; Fluid Therapy; Gastroenteritis; Hos | 2011 |
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.
Topics: Acute Disease; Adolescent; Antiemetics; Child; Gastroenteritis; Humans; Metoclopramide; Ondansetron; | 2006 |
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.
Topics: Acute Disease; Adolescent; Antiemetics; Child; Gastroenteritis; Humans; Metoclopramide; Ondansetron; | 2006 |
4 trials available for metoclopramide and Gastroenteritis
| Article | Year |
|---|---|
Metoclopramide versus ondansetron for the treatment of vomiting in children with acute gastroenteritis.
Topics: Adolescent; Antiemetics; Child; Child, Preschool; Dopamine Antagonists; Double-Blind Method; Female; | 2011 |
Antiemetic activity of ondansetron in acute gastroenteritis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Diarrhea; Female; Fluid Therapy; Gastroenteriti | 1997 |
A double-blind comparison of domperidone and metoclopramide suppositories in the treatment of nausea and vomiting in children.
Topics: Antiemetics; Benzimidazoles; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; | 1979 |
[The therapy of gastroduodenal diseases. Results of a randomized double-blind study of gastroduodenal diseases with the new mono-substance viaben].
Topics: Adult; Aged; Double-Blind Method; Drug Evaluation; Female; Gastroenteritis; Humans; Male; Metoclopra | 1978 |
11 other studies available for metoclopramide and Gastroenteritis
| Article | Year |
|---|---|
Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting.
Topics: Adult; Antiemetics; Diphenhydramine; Dyskinesias; Female; Gastroenteritis; Humans; Injections, Intra | 2014 |
Emergency department management of gastro-enteritis in Australia and New Zealand.
Topics: Acute Disease; Antiemetics; Australia; Data Collection; Dehydration; Diarrhea; Emergency Medicine; E | 2008 |
Case of acute akathisia from intravenous metoclopramide.
Topics: Abdominal Pain; Adult; Akathisia, Drug-Induced; Diphenhydramine; Emergency Service, Hospital; Female | 2011 |
Antiemetics for acute gastroenteritis-related vomiting in children and adolescents.
Topics: Acute Disease; Adolescent; Antiemetics; Child; Dimenhydrinate; Gastroenteritis; Humans; Metocloprami | 2012 |
[Urinary retention in 2 children after the use of antiemetic agents during acute gastroenteritis].
Topics: Acute Disease; Antiemetics; Child, Preschool; Domperidone; Dopamine Antagonists; Female; Gastroenter | 2005 |
[Gastric emptying in dyspeptic syndromes during treatment with a combination of carbenoxolone and metoclopramide, studied with a meal labeled with 99mTc colloidal sulfate].
Topics: Adult; Aged; Carbenoxolone; Chronic Disease; Drug Therapy, Combination; Dyspepsia; Female; Gastric E | 1980 |
Diverse effects of antiemetics in children.
Topics: Antiemetics; Basal Ganglia Diseases; Child; Child, Preschool; Drug Overdose; Female; Gastroenteritis | 1994 |
Index of suspicion. Case 3. Drug-induced movement disorder.
Topics: Acute Disease; Child; Diagnosis, Differential; Dyskinesia, Drug-Induced; Female; Gastroenteritis; Hu | 1994 |
[A 'suppository for vomiting prevention'].
Topics: Antiemetics; Basal Ganglia Diseases; Child; Child, Preschool; Diagnosis, Differential; Domperidone; | 1997 |
Sudden onset of slow gastric emptying of food.
Topics: Adolescent; Adult; Female; Gastric Emptying; Gastroenteritis; Humans; Male; Metoclopramide; Stomach | 1979 |
[Uncharacteristic hypertonia resulting from treatment with metoclopramide (Primperan) in children with acute gastroenteritis].
Topics: Acute Disease; Biperiden; Gastroenteritis; Humans; Infant; Male; Metoclopramide; Muscle Tonus; Muscu | 1977 |