Page last updated: 2024-10-31

metoclopramide and Galactorrhea

metoclopramide has been researched along with Galactorrhea in 38 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.

Research Excerpts

ExcerptRelevanceReference
"Gynecomastia and galactorrhea stemming from hyperprolactinemia have been reported in adults after the use of metoclopramide."7.69Gynecomastia with metoclopramide use in pediatric patients. ( Madani, S; Tolia, V, 1997)
"Diffuse hemangiomatosis of the liver became apparent in a 22-year-old woman while she was receiving medication with metoclopramide and experiencing the well-known adverse effect of the drug, hyperprolactinemia with secondary amenorrhea and galactorrhea."7.68Arteriovenous shunting and cholestasis in hepatic hemangiomatosis associated with metoclopramide. ( Feurle, GE, 1990)
"The degree of autonomy in prolactin secreting pituitary adenomas and also prolactin secretory reserve in cases with suspected functional galactorrhea syndrome was evaluated with the use of metoclopramide, TRH and L-DOPA."7.66The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome. ( Jeske, W, 1979)
"The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases."7.66Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978)
"2 mg) in 8 healthy human subjects (4F/4M) aged 18-50 years, and oral metoclopramide (MCP) test (10 mg) in 8 females with galactorrhea and regular menstruation aged 18-52 years."5.07Increased interleukin-2 levels during standard TRH test in man. ( Komorowski, J; Pawlikowski, M; Stepień, H, 1994)
"Gynecomastia and galactorrhea stemming from hyperprolactinemia have been reported in adults after the use of metoclopramide."3.69Gynecomastia with metoclopramide use in pediatric patients. ( Madani, S; Tolia, V, 1997)
" The determination of prolactin concentration after the administration of metoclopramide made possible the diagnosis of functional hyperprolactinaemia."3.68[A case of functional hyperprolactinemia]. ( Kapłon, E; Przybyłowski, J; Siedlecki, J, 1992)
"A 21 year old female treated for recurring gastric troubles with dopamine-antagonists (domperidone, metoclopramide) developed a clinically manifest hyperprolactinemia (3055 microU/l; normal value < 650 microU/l) with galactorrhea only two days after a new two day course of metoclopramide."3.68[Drug-induced hyperprolactinemia and galactorrhea]. ( Bozzolo, M; Haefeli, WE; Lüscher, TF; Noll, G, 1992)
" To investigate these differences in PRL secretion, we have characterized the molecular forms of circulating PRL in postpartum women during breastfeeding (n = 5) and sleep (n = 5) and in eumenorrheic women with galactorrhea (n = 5) after TRH stimulation (n = 4), metaclopramide infusion (n = 5), and morphine administration (n = 2)."3.68Differential release of prolactin variants in postpartum and early follicular phase women. ( Lee, DW; Liu, JH; Markoff, E, 1990)
"Diffuse hemangiomatosis of the liver became apparent in a 22-year-old woman while she was receiving medication with metoclopramide and experiencing the well-known adverse effect of the drug, hyperprolactinemia with secondary amenorrhea and galactorrhea."3.68Arteriovenous shunting and cholestasis in hepatic hemangiomatosis associated with metoclopramide. ( Feurle, GE, 1990)
"TRH, metoclopramide (MCP), chlorpromazine (CPZ), and insulin (ITT) stimulation tests of PRL secretion were carried out in age-matched controls and before and after successful removal of pituitary prolactinomas in women with the galactorrhea-amenorrhea syndrome."3.66Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome. ( Blackard, WG; Gardner, DF; Lankford, HV; Tucker, HS, 1980)
"The degree of autonomy in prolactin secreting pituitary adenomas and also prolactin secretory reserve in cases with suspected functional galactorrhea syndrome was evaluated with the use of metoclopramide, TRH and L-DOPA."3.66The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome. ( Jeske, W, 1979)
"The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases."3.66Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978)
"Galactorrhea was associated with the following conditions: hyperprolactinemia (34."1.28[The value of hyperprolactinemia determination within the scope of galactorrhea]. ( Enzelsberger, H; Kubista, E; Schurz, B; Wenzl, R, 1989)
"Women with spontaneous primary hypothyroidism had a longer duration of illness (72 +/- 12 vs."1.26Hyperprolactinemia and galactorrhea: spontaneous versus iatrogenic hypothyroidism. ( Campino, C; Contreras, P; Generini, G; Michelsen, H; Pumarino, H, 1981)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199024 (63.16)18.7374
1990's8 (21.05)18.2507
2000's5 (13.16)29.6817
2010's0 (0.00)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Cazorla-Ortiz, G1
Obregón-Guitérrez, N1
Rozas-Garcia, MR1
Goberna-Tricas, J1
Paturi, B1
Ryan, RM1
Michienzi, KA1
Lakshminrusimha, S1
Noczyńska, A1
Wasikowa, R1
Edwards, L1
Bohnet, HG1
Fischer, R1
Weise, HC1
Leidenberger, FA1
Komorowski, JM1
Reterski, Z1
Owczarczyk, I2
Tornai, I1
Kulcsár, A1
Udvardy, M1
Pawlikowski, M2
Komorowski, J2
Tucker, HS2
Lankford, HV2
Gardner, DF1
Blackard, WG2
de Rosa, G1
Gulino, A1
de Rosa, E1
Satta, MA1
Aiello, A1
Makhoul, O1
Pasargiklian, E1
Grubb, SR1
Wigand, JP1
Taylon, A1
Becker, DP1
Shanmugasundaram, K1
Jason, DA1
Rao, PV1
Elanchezhian, C1
Contreras, P1
Generini, G1
Michelsen, H1
Pumarino, H1
Campino, C1
Giacovazzo, M1
Cooper, BT1
Mountford, RA1
McKee, C1
Stepień, H1
Madani, S1
Tolia, V1
Oudesluys-Murphy, AM1
Snowden, H1
Woolridge, M1
Renfrew, M1
Jeske, W1
Aono, T2
Shioji, T1
Kinugasa, T1
Onishi, T1
Kurachi, K1
Healy, DL1
Pepperell, RJ1
Stockdale, J1
Bremner, WJ1
Burger, HG1
Yamamoto, T1
Ohtsuru, N1
Sugita, M1
Horai, Z1
Matsumura, S1
Vázquez-Matute, L1
Canales, ES1
Alger, M1
Zárate, A1
Tamagna, EI1
Lane, W1
Hershman, JM1
Carlson, HE1
Sturdevant, RA1
Poland, RE1
Rubin, RT1
Larsen, S1
Sørensen, T1
Judd, SJ1
Lazarus, L1
Compton, P1
Finnis, WA1
Bird, CE1
Wilson, DL1
Przybyłowski, J1
Siedlecki, J1
Kapłon, E1
Bozzolo, M1
Haefeli, WE1
Noll, G1
Lüscher, TF1
Yarkony, GM1
Novick, AK1
Roth, EJ1
Kirschner, KL1
Rayner, S1
Betts, HB1
Yamaguchi, M1
Koike, K1
Nishikawa, Y1
Ikegami, H1
Miyake, A1
Tanizawa, O1
Liu, JH1
Lee, DW1
Markoff, E1
Feurle, GE1
Schurz, B1
Enzelsberger, H1
Kubista, E1
Wenzl, R1
Langner, TK1
Mel'nichenko, GA1
Dedov, II1
Saakian, OA1
Gitel', EP1
Porias Cuéllas, HL1
Hernández Bueno, JA1
Villanueva, C1
Benavides, S1
Cortés-Gallegos, V1
Day, JO1

Reviews

1 review available for metoclopramide and Galactorrhea

ArticleYear
Methods and Success Factors of Induced Lactation: A Scoping Review.
    Journal of human lactation : official journal of International Lactation Consultant Association, 2020, Volume: 36, Issue:4

    Topics: Adult; Breast Feeding; Dopamine D2 Receptor Antagonists; Female; Galactorrhea; Humans; Lactation; Me

2020

Trials

1 trial available for metoclopramide and Galactorrhea

ArticleYear
Increased interleukin-2 levels during standard TRH test in man.
    Neuropeptides, 1994, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Cytokines; Female; Galactorrhea; Humans; Immune System; Interleukin-2; Male; Meto

1994

Other Studies

36 other studies available for metoclopramide and Galactorrhea

ArticleYear
Galactorrhea with metoclopramide use in the neonatal unit.
    Journal of perinatology : official journal of the California Perinatal Association, 2009, Volume: 29, Issue:5

    Topics: Abnormalities, Multiple; Down Syndrome; Ductus Arteriosus, Patent; Follow-Up Studies; Galactorrhea;

2009
Hyperprolactinemia in children during the peripubertal period--personal observations.
    Journal of pediatric endocrinology & metabolism : JPEM, 2004, Volume: 17, Issue:10

    Topics: Adolescent; Age Factors; Amenorrhea; Biomarkers; Female; Galactorrhea; Gynecomastia; Humans; Hyperpr

2004
Hyperprolactinaemia in a patient with cystic fibrosis.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Cystic Fibrosis; Domperidone; Drug Combination

2007
[Diagnostic value of the prolactin stimulation test in infertile women with galactorrhea].
    Fortschritte der Medizin, 1984, Apr-12, Volume: 102, Issue:14

    Topics: Female; Galactorrhea; Humans; Infertility, Female; Lactation Disorders; Metoclopramide; Pregnancy; P

1984
Acupuncture therapy does not change metoclopramide-induced prolactin secretion in normoprolactinaemic galactorrhea syndrome.
    Endokrynologia Polska, 1984, Volume: 35, Issue:4

    Topics: Acupuncture Therapy; Adult; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregn

1984
[Galactorrhea induced by metoclopramid].
    Orvosi hetilap, 1983, Apr-24, Volume: 124, Issue:17

    Topics: Adult; Bromocriptine; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy;

1983
[Serum prolactin level in basal conditions and after metoclopramide stimulation in women with galactorrhea and in patients with pituitary tumors].
    Endokrynologia Polska, 1983, Volume: 34, Issue:4

    Topics: Adult; Female; Galactorrhea; Humans; Lactation Disorders; Male; Metoclopramide; Pituitary Neoplasms;

1983
Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:5

    Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Insulin; Lactation Disorders; Metocloprami

1980
[Effects of citicholine on pituitary gland function in normal subjects and in cases of idiopathic galactorrhea].
    La Clinica terapeutica, 1980, Aug-31, Volume: 94, Issue:4

    Topics: Adolescent; Adult; Choline; Cimetidine; Cytidine Diphosphate Choline; Female; Galactorrhea; Growth H

1980
Galactorrhea-amenorrhea syndrome: follow-up of forty-five patients after pituitary tumor removal.
    Annals of internal medicine, 1981, Volume: 94, Issue:3

    Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Female; Follow-Up Studies; Galactorrhea; Humans; Lactati

1981
Galactorrhoea.
    Journal of the Indian Medical Association, 1982, Apr-16, Volume: 78, Issue:8

    Topics: Adult; Female; Galactorrhea; Humans; Hypothalamo-Hypophyseal System; Lactation Disorders; Metoclopra

1982
Hyperprolactinemia and galactorrhea: spontaneous versus iatrogenic hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Aged; Female; Galactorrhea; Humans; Hypothyroidism; Iatrogenic Disease; Lactation

1981
[Menstrual migraine].
    Minerva medica, 1982, Mar-24, Volume: 73, Issue:12

    Topics: Adult; Bromocriptine; Chiari-Frommel Syndrome; Estrogens; Female; Galactorrhea; Gout; Humans; Menstr

1982
Galactorrhoea, hyperprolactinaemia, and pituitary adenoma presenting during metoclopramide therapy.
    Postgraduate medical journal, 1982, Volume: 58, Issue:679

    Topics: Adenoma; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Middle Aged; Pituitary N

1982
Gynecomastia with metoclopramide use in pediatric patients.
    Journal of clinical gastroenterology, 1997, Volume: 24, Issue:2

    Topics: Adolescent; Dopamine Antagonists; Galactorrhea; Gastroesophageal Reflux; Gynecomastia; Humans; Infan

1997
Galactorrhoea, hyperprolactinaemia, and protease inhibitors.
    Lancet (London, England), 2001, Feb-10, Volume: 357, Issue:9254

    Topics: Drug Therapy, Combination; Female; Galactorrhea; HIV Infections; HIV Protease Inhibitors; Humans; La

2001
Galactorrhoea, hyperprolactinaemia, and protease inhibitors.
    Lancet (London, England), 2001, Feb-10, Volume: 357, Issue:9254

    Topics: Drug Therapy, Combination; Female; Fluoxetine; Galactorrhea; HIV Infections; HIV Protease Inhibitors

2001
The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome.
    Acta endocrinologica, 1979, Volume: 91, Issue:3

    Topics: Acromegaly; Adenoma; Adult; Amenorrhea; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa;

1979
Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:3

    Topics: Adult; Female; Follicle Stimulating Hormone; Galactorrhea; Gastrointestinal Diseases; Gonadotropin-R

1978
Pituitary autonomy in hyperprolactinemic secondary amenorrhea: results of hypothalamic-pituitary testing.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:5

    Topics: Adult; Amenorrhea; Bromocriptine; Clomiphene; Female; Galactorrhea; Humans; Hypothalamo-Hypophyseal

1977
[Blood prolactin study in four cases of galactorrhea (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1977, May-10, Volume: 66, Issue:5

    Topics: Administration, Oral; Adult; Female; Galactorrhea; Humans; Lactation Disorders; Male; Metoclopramide

1977
Clinical use of metoclopramide test in the diagnosis of women with hyperprolactinemia.
    Hormone research, 1979, Volume: 10, Issue:4

    Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Male; Metoclopramide; Pituitary Neoplasms; Pregnanc

1979
Effect of chronic metoclopramide therapy on serum pituitary hormone concentrations.
    Hormone research, 1979, Volume: 11, Issue:4

    Topics: Adult; Aged; Erectile Dysfunction; Female; Galactorrhea; Humans; Male; Metoclopramide; Middle Aged;

1979
[Hyperprolactinemia and galactorrhea induced by metoclopramide (Primperan)].
    Ugeskrift for laeger, 1979, Oct-15, Volume: 141, Issue:42

    Topics: Adolescent; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy; Prolactin

1979
Hyperprolactinaemia: its physiology and investigation.
    The Medical journal of Australia, 1976, Jul-03, Volume: 2, Issue:1

    Topics: Adenoma, Chromophobe; Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Male; Metabolic Disea

1976
Metoclopramide hydrochloride and galactorrhea.
    Canadian Medical Association journal, 1976, Nov-06, Volume: 115, Issue:9

    Topics: Adult; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy

1976
[A case of functional hyperprolactinemia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:19-20

    Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Hyperprolactinemia; Metoclopramide; Neurotic Disord

1992
[Drug-induced hyperprolactinemia and galactorrhea].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Dec-08, Volume: 81, Issue:50

    Topics: Adult; Female; Galactorrhea; Humans; Hyperprolactinemia; Metoclopramide; Prolactin

1992
Galactorrhea: a complication of spinal cord injury.
    Archives of physical medicine and rehabilitation, 1992, Volume: 73, Issue:9

    Topics: Adult; Female; Galactorrhea; Humans; Metoclopramide; Prolactin; Spinal Cord Injuries

1992
Effects of nocturnal hyperprolactinemia on ovarian luteal function and galactorrhea.
    European journal of obstetrics, gynecology, and reproductive biology, 1991, May-10, Volume: 39, Issue:3

    Topics: Adult; Circadian Rhythm; Corpus Luteum; Female; Galactorrhea; Humans; Hyperprolactinemia; Luteinizin

1991
Differential release of prolactin variants in postpartum and early follicular phase women.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:3

    Topics: Adult; Bottle Feeding; Breast Feeding; Female; Follicular Phase; Galactorrhea; Humans; Metoclopramid

1990
Arteriovenous shunting and cholestasis in hepatic hemangiomatosis associated with metoclopramide.
    Gastroenterology, 1990, Volume: 99, Issue:1

    Topics: Adult; Angiography; Angiomatosis; Cholestasis; Female; Galactorrhea; Humans; Hyperprolactinemia; Liv

1990
[The value of hyperprolactinemia determination within the scope of galactorrhea].
    Zentralblatt fur Gynakologie, 1989, Volume: 111, Issue:1

    Topics: Adult; Female; Fibrocystic Breast Disease; Galactorrhea; Humans; Hyperprolactinemia; Lactation Disor

1989
[Diagnostic value of pharmacological tests and roentgenoradiological methods in the diagnosis of various forms of hyperprolactinemic hypogonadism].
    Akusherstvo i ginekologiia, 1986, Issue:7

    Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Hyperprolactinemia; Lactation Disorders; Metoclopra

1986
[The physiopathological aspects of the normoprolactinemic amenorrhea-galactorrhea syndrome].
    Ginecologia y obstetricia de Mexico, 1987, Volume: 55

    Topics: Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Hyperprolactinemia; Metoclopramide; Prolact

1987
Metoclopramide-induced galactorrhea.
    Journal of the Medical Association of Georgia, 1987, Volume: 76, Issue:11

    Topics: Adult; Female; Galactorrhea; Humans; Hyperprolactinemia; Lactation Disorders; Metoclopramide

1987