Page last updated: 2024-10-31

metoclopramide and Esophagitis, Reflux

metoclopramide has been researched along with Esophagitis, Reflux in 56 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"The effect of oral metoclopramide (15 mg), AlMgOH (30 ml), and placebo on the cumulative duration of gastroesophageal reflux induced by a protein-rich meal was compared in 15 patients with reflux esophagitis."9.04Effect of oral metoclopramide on gastroesophageal reflux in the post-cibal state. ( Behar, J; Biancani, P, 1976)
"The effect of oral metoclopramide (15 mg), AlMgOH (30 ml), and placebo on the cumulative duration of gastroesophageal reflux induced by a protein-rich meal was compared in 15 patients with reflux esophagitis."5.04Effect of oral metoclopramide on gastroesophageal reflux in the post-cibal state. ( Behar, J; Biancani, P, 1976)
"Conventional medical treatment for gastroesophageal reflux disease involves life-style modifications and combination drug therapy, but few studies have included these features in their protocols."2.67Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. The Department of Veterans Affairs Gastroesophageal Reflux Disease Study Group. ( Spechler, SJ, 1992)
"Medical treatment of gastroesophageal reflux disease often results in improvement of symptoms."2.6624-hour esophageal pH monitoring before and after medical therapy for reflux esophagitis. ( Lieberman, DA, 1988)
"The vast majority of patients with GERD have mild symptoms, no gross endoscopic evidence of esophagitis, and little risk of developing complications."2.39Influence of pathophysiology, severity, and cost on the medical management of gastroesophageal reflux disease. ( Reynolds, JC, 1996)
" Dinnertime dosing of cimetidine appears to be a rational method of suppressing late-evening gastric acidity."2.38Drug therapy of reflux oesophagitis: an update. ( Tytgat, GN, 1989)
"Gastro-oesophageal reflux disease is a very common disorder."1.29[Internal medicine therapy in reflux disease]. ( Flad, J, 1996)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199046 (82.14)18.7374
1990's8 (14.29)18.2507
2000's1 (1.79)29.6817
2010's1 (1.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heiberger, A1
Chapman, MJ1
Nguyen, NQ1
Fraser, RJ1
Holloway, RH1
Winnan, G1
McCallum, RW1
Richter, JE4
Castell, DO7
Wesdorp, IC1
Farthmann, EH1
Fritsch, WP1
Markham, C1
Reed, PI1
Lebas de Lacour, JC1
Christoforov, B1
Jammet, P1
Caruana, A1
Guslandi, M1
Testoni, PA1
Passaretti, S1
Masci, E1
Ballarin, E1
Comin, U1
Marchi, R1
Ronchi, G1
Tittobello, A1
Valenzuela, JE1
Dooley, CP1
Burns, TW1
Weihrauch, TR1
Kilbinger, H1
Rhodes, J1
Teilum, D1
Ferraris, R1
Catrambone, G1
Parodi, A1
Ferrigno, S1
Ruffo, A1
Kim, EE1
Choy, YC1
Domstad, PA1
Beihn, R1
Coupal, J1
Yonts, S1
DeLand, FH1
Siewert, R1
Blum, AL1
Halter, F1
McLoughlin, J1
Miller, AJ1
Robinson, M1
Decktor, DL1
Maton, PN1
Sabesin, S1
Roufail, W1
Kogut, D1
Roberts, W1
McCullough, A1
Pardoll, P1
Saco, L1
McDougall, NI1
Johnston, BT1
Kee, F1
Collins, JS1
McFarland, RJ1
Love, AH1
Sabesin, SM1
Kogut, DG1
Kerr, RM1
Wruble, LD1
Collen, MJ1
Reynolds, JC1
Flad, J1
Hollander, D1
Karris, G1
Lauritsen, KB1
Kragelund, E1
Møller, I1
Behar, J4
Ramsby, G1
Roufail, WM1
Cirino, E1
Bianca, T1
Palomba, R1
Fusto, A1
Mantelmacher, H1
Bettarello, A1
Ottenjann, R1
Biancani, P1
Spechler, SJ1
Grande, L1
Lacima, G1
Ros, E1
García-Valdecasas, JC1
Fuster, J1
Visa, J1
Pera, C1
Tytgat, GN3
Monés, J1
Espinós, JC1
Carrió, I1
Calabuig, R1
Vilardell, F1
Nelson, JL1
Vantrappen, G1
Janssens, J1
Nio, CY1
Geller, LI1
Petrenko, VF1
Lieberman, DA3
Jali, MV1
Joglekar, MD1
Tønnesen, H1
Andersen, JR1
Christoffersen, P1
Kaas-Claesson, N1
Keeffe, EB1
Berlin, RG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study[NCT01574573]52 participants (Actual)Interventional2009-06-30Terminated (stopped due to Closed due to lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for metoclopramide and Esophagitis, Reflux

ArticleYear
Gastrointestinal motility and prokinetics in the critically ill.
    Current opinion in critical care, 2007, Volume: 13, Issue:2

    Topics: Cisapride; Critical Care; Enteral Nutrition; Erythromycin; Esophagitis, Peptic; Gastric Emptying; Ga

2007
Upper gastrointestinal motility. Part I--The pathophysiologic approach to the management of reflux esophagitis.
    The American journal of gastroenterology, 1981, Volume: 76, Issue:3

    Topics: Antacids; Bethanechol Compounds; Carbenoxolone; Esophagitis, Peptic; Esophagogastric Junction; Gastr

1981
Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy.
    Annals of internal medicine, 1982, Volume: 97, Issue:1

    Topics: Alginates; Antacids; Barium Sulfate; Bethanechol; Bethanechol Compounds; Cimetidine; Esophagitis, Pe

1982
Dopamine antagonists in the upper gastrointestinal tract.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 96

    Topics: Diabetic Neuropathies; Digestive System; Domperidone; Dopamine Antagonists; Duodenum; Dyspepsia; Eso

1984
[Motility-effective drugs for therapy of gastrointestinal functional disorders].
    Deutsche medizinische Wochenschrift (1946), 1982, Sep-03, Volume: 107, Issue:35

    Topics: Bethanechol Compounds; Carbachol; Domperidone; Esophagitis, Peptic; Gastrointestinal Diseases; Gastr

1982
Drugs, foods, and other substances in the cause and treatment of reflux esophagitis.
    The Medical clinics of North America, 1981, Volume: 65, Issue:6

    Topics: Alginates; Antacids; Bethanechol Compounds; Cimetidine; Esophagitis, Peptic; Food; Gastric Acid; Hum

1981
Influence of pathophysiology, severity, and cost on the medical management of gastroesophageal reflux disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Nov-15, Volume: 53, Issue:22 Suppl 3

    Topics: Aged; Anti-Ulcer Agents; Cisapride; Drug Interactions; Drug Therapy, Combination; Esophagitis, Pepti

1996
Reflux esophagitis: pathogenesis, diagnosis, and management.
    Archives of internal medicine, 1976, Volume: 136, Issue:5

    Topics: Antacids; Biopsy; Esophagitis, Peptic; Esophagogastric Junction; Esophagoscopy; Gastrins; Heartburn;

1976
Drug therapy of reflux oesophagitis: an update.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 168

    Topics: Antacids; Bethanechol; Bethanechol Compounds; Cisapride; Domperidone; Esophagitis, Peptic; Histamine

1989
Reflux esophagitis: an update.
    Southern medical journal, 1985, Volume: 78, Issue:4

    Topics: Alginates; Antacids; Barium Sulfate; Bethanechol; Bethanechol Compounds; Combined Modality Therapy;

1985
The medical therapy of reflux oesophagitis.
    Bailliere's clinical gastroenterology, 1987, Volume: 1, Issue:4

    Topics: Antacids; Bethanechol; Bethanechol Compounds; Cimetidine; Cisapride; Domperidone; Esophagitis, Pepti

1987

Trials

14 trials available for metoclopramide and Esophagitis, Reflux

ArticleYear
Ranitidine vs metoclopramide in the medical treatment of reflux esophagitis.
    Hepato-gastroenterology, 1983, Volume: 30, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Esophagitis, Peptic; Female; Furans; Humans; Mal

1983
Medical therapy of reflux esophagitis.
    Annals of internal medicine, 1980, Volume: 93, Issue:6

    Topics: Antacids; Bethanechol Compounds; Cimetidine; Clinical Trials as Topic; Esophagitis, Peptic; Humans;

1980
Metoclopramide in the treatment of reflux oesophagitis: a comparison of normal and controlled-release formulations.
    Current medical research and opinion, 1993, Volume: 13, Issue:3

    Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Delayed-Action Preparations; Esophagitis, P

1993
Omeprazole is superior to ranitidine plus metoclopramide in the short-term treatment of erosive oesophagitis.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7, Issue:1

    Topics: Adult; Antacids; Circadian Rhythm; Drug Therapy, Combination; Esophagitis, Peptic; Female; Gastroeso

1993
Omeprazole versus ranitidine or ranitidine/metoclopramide in poorly responsive symptomatic gastroesophageal reflux disease.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:9

    Topics: Dopamine Antagonists; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Es

1996
Gastric emptying and antral motility in reflux esophagitis. Effect of oral metoclopramide.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 1

    Topics: Administration, Oral; Adult; Eating; Esophagitis, Peptic; Fasting; Gastric Emptying; Gastrointestina

1978
Effect of oral metoclopramide on gastroesophageal reflux in the post-cibal state.
    Gastroenterology, 1976, Volume: 70, Issue:3

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Dietary Proteins; Eating; Esophagitis, Peptic

1976
Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. The Department of Veterans Affairs Gastroesophageal Reflux Disease Study Group.
    The New England journal of medicine, 1992, Mar-19, Volume: 326, Issue:12

    Topics: Antacids; Combined Modality Therapy; Esophagitis, Peptic; Female; Follow-Up Studies; Gastric Fundus;

1992
Lack of effect of metoclopramide and domperidone on esophageal peristalsis and esophageal acid clearance in reflux esophagitis. A randomized, double-blind study.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:4

    Topics: Adult; Domperidone; Double-Blind Method; Esophagitis, Peptic; Esophagogastric Junction; Esophagus; F

1992
[Gastric emptying in reflux esophagitis. Effect of metoclopramide and cinitapride].
    Medicina clinica, 1989, Sep-30, Volume: 93, Issue:9

    Topics: Aged; Benzamides; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Esophagitis, Pepti

1989
Medical therapy for chronic reflux esophagitis. Long-term follow-up.
    Archives of internal medicine, 1987, Volume: 147, Issue:10

    Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination;

1987
24-hour esophageal pH monitoring before and after medical therapy for reflux esophagitis.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:2

    Topics: Cimetidine; Esophagitis, Peptic; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration

1988
Reflux oesophagitis in heavy drinkers. Effect of ranitidine and alginate/metoclopramide.
    Digestion, 1987, Volume: 38, Issue:2

    Topics: Adult; Alcoholism; Alginates; Double-Blind Method; Drug Therapy, Combination; Esophagitis, Peptic; E

1987
Treatment of severe reflux esophagitis with cimetidine and metoclopramide.
    Annals of internal medicine, 1986, Volume: 104, Issue:1

    Topics: Biopsy; Cimetidine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Esophagitis, Pe

1986

Other Studies

31 other studies available for metoclopramide and Esophagitis, Reflux

ArticleYear
Managing reflux in infants: lifestyle modifications or medications?
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2014, Volume: 67, Issue:6

    Topics: Antiemetics; Child Development; Disease Management; Esophagitis, Peptic; Gastroesophageal Reflux; Hi

2014
Treatment of reflux oesophagitis.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 79

    Topics: Alginates; Aluminum Hydroxide; Antacids; Anti-Ulcer Agents; Barrett Esophagus; Bethanechol Compounds

1982
[Conditions after total gastrectomy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1982, Volume: 17

    Topics: Adenocarcinoma; Anemia, Hypochromic; Antacids; Cholestyramine Resin; Dumping Syndrome; Esophagitis,

1982
Pyrogastrone treatment of peptic oesophagitis: analysis of 104 patients treated during a 3 1/2-year period.
    Scandinavian journal of gastroenterology. Supplement, 1980, Volume: 65

    Topics: Adult; Aged; Alginates; Aluminum Hydroxide; Bicarbonates; Carbenoxolone; Cimetidine; Drug Combinatio

1980
[Reflux esophagitis. Etiologies, mechanisms and therapeutic directions].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Oct-14, Volume: 58, Issue:37

    Topics: Alginates; Cimetidine; Esophagitis, Peptic; Hernia, Hiatal; Humans; Metoclopramide

1982
Motor disorders of the esophagus: diagnosis and treatment.
    Southern medical journal, 1984, Volume: 77, Issue:8

    Topics: Bethanechol Compounds; Calcium Channel Blockers; Esophageal Achalasia; Esophageal Diseases; Esophagi

1984
Oesophagitis and the role of antacid therapy.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 75

    Topics: Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Carbenoxolone; Cimetidine; Drug Combinations;

1982
Reflux esophagitis.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:2

    Topics: Antacids; Biopsy; Cholestyramine Resin; Cimetidine; Endoscopy; Esophagitis, Peptic; Esophagogastric

1982
[Medical management of reflux esophagitis].
    Minerva medica, 1982, Nov-10, Volume: 73, Issue:43

    Topics: Alginates; Antacids; Carbenoxolone; Cimetidine; Esophagitis, Peptic; Esophagogastric Junction; Femal

1982
Biologic gastric emptying time using Tc-99m TETA polystyrene resin in various clinical conditions.
    European journal of nuclear medicine, 1981, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Esophagitis, Peptic; Ethylenediamines; Female; Gastrecto

1981
[Therapy of esophageal reflux disease].
    Deutsche medizinische Wochenschrift (1946), 1980, Dec-26, Volume: 105, Issue:52

    Topics: Aluminum Hydroxide; Esophagitis; Esophagitis, Peptic; Esophagoscopy; Gastroesophageal Reflux; Humans

1980
[Reflux esophagitis - conservative therapy or surgery? Benign differential therapy for esophageal diseases (I)].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1980, Volume: 56, Issue:29

    Topics: Cimetidine; Esophagitis, Peptic; Humans; Metoclopramide

1980
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
[Internal medicine therapy in reflux disease].
    Praxis, 1996, Nov-05, Volume: 85, Issue:45

    Topics: Antacids; Antiemetics; Clinical Protocols; Esophagitis, Peptic; Gastroesophageal Reflux; Gastrointes

1996
Medical measures that influence the gastroesophageal junction.
    Southern medical journal, 1978, Volume: 71 Suppl 1

    Topics: Alginates; Alkalies; Aluminum Hydroxide; Bethanechol Compounds; Bicarbonates; Drug Combinations; Eso

1978
Efficacy of medical management of gastroesophageal reflux: a critical assessment.
    Southern medical journal, 1978, Volume: 71 Suppl 1

    Topics: Alginates; Aluminum Hydroxide; Antacids; Bethanechol Compounds; Bicarbonates; Drug Combinations; Eso

1978
[Reflux esophagitis. Results of medical and surgical treatment].
    Ugeskrift for laeger, 1979, Sep-03, Volume: 141, Issue:36

    Topics: Esophagitis, Peptic; Humans; Methods; Metoclopramide; Prospective Studies; Vagotomy

1979
Medical management of patients with reflux esophagitis.
    Southern medical journal, 1978, Volume: 71 Suppl 1

    Topics: Alginates; Antacids; Bethanechol Compounds; Cimetidine; Esophagitis, Peptic; Heartburn; Humans; Meto

1978
[Current trends in the treatment of reflux esophagitis in childhood].
    Chirurgia italiana, 1978, Volume: 30, Issue:5

    Topics: Antacids; Cardia; Child, Preschool; Esophageal Stenosis; Esophagitis, Peptic; Hernia, Hiatal; Humans

1978
[Therapy of reflux esophagitis. Manometric determination of the effect of bromoprid on the lower esophageal sphincter].
    Fortschritte der Medizin, 1978, Nov-02, Volume: 96, Issue:41

    Topics: Adolescent; Adult; Esophagitis, Peptic; Esophagogastric Junction; Female; Humans; Male; Manometry; M

1978
[Indication for conservative therapy of reflux esophagitis (author's transl)].
    Langenbecks Archiv fur Chirurgie, 1978, Volume: 347

    Topics: Alginates; Antacids; Cimetidine; Esophagitis, Peptic; Humans; Metoclopramide

1978
Medical management of reflux esophagitis.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Antacids; Bethanechol; Bethanechol Compounds; Diagnosis, Differential; Diet; Domperidone; Esophagiti

1985
Medical therapy for reflux esophagitis: 1986 and beyond.
    Annals of internal medicine, 1986, Volume: 104, Issue:1

    Topics: Bethanechol; Bethanechol Compounds; Cimetidine; Drug Therapy, Combination; Esophagitis, Peptic; Gast

1986
Treatment of severe reflux esophagitis.
    Annals of internal medicine, 1986, Volume: 104, Issue:4

    Topics: Bethanechol; Bethanechol Compounds; Drug Therapy, Combination; Esophagitis, Peptic; Histamine H2 Ant

1986
Future medical therapy of reflux esophagitis.
    Journal of clinical gastroenterology, 1986, Volume: 8 Suppl 1

    Topics: Animals; Chronic Disease; Drug Therapy, Combination; Esophagitis, Peptic; Gastric Acid; Gastrointest

1986
[Therapeutic procedures in gastroesophageal reflux disease].
    Zeitschrift fur Gastroenterologie, 1986, Volume: 24 Suppl 2

    Topics: Alginates; Aluminum Hydroxide; Antacids; Bicarbonates; Combined Modality Therapy; Dilatation; Domper

1986
[Disorders of esophageal motility as a cause of retrosternal pain].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M

1986
Metoclopromide and "asthma". Case report.
    Indian journal of medical sciences, 1988, Volume: 42, Issue:2

    Topics: Asthma; Esophagitis, Peptic; Female; Humans; Metoclopramide; Middle Aged

1988
Cimetidine-metoclopramide combination works in severe reflux esophagitis.
    American pharmacy, 1986, Volume: NS26, Issue:4

    Topics: Cimetidine; Esophagitis, Peptic; Humans; Metoclopramide

1986
The role of the lower esophageal sphincter in reflux prevention.
    Journal of clinical gastroenterology, 1986, Volume: 8 Suppl 1

    Topics: Animals; Cardia; Dogs; Epithelium; Esophagitis, Peptic; Esophagogastric Junction; Humans; Manometry;

1986
Metoclopramide-induced reversible impotence.
    The Western journal of medicine, 1986, Volume: 144, Issue:3

    Topics: Aged; Duodenal Ulcer; Erectile Dysfunction; Esophagitis, Peptic; Humans; Male; Metoclopramide; Middl

1986