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metoclopramide and Esophageal Varices

metoclopramide has been researched along with Esophageal Varices in 19 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"We examined the preventive effect of metoclopramide on the development of esophageal varices in a rat model."7.69Metoclopramide inhibits development of esophageal varices in rat model. ( Hashizume, M; Ishii, T; Kitano, S; Komori, K; Ohta, M; Sugimachi, K; Tanoue, K; Ueno, K, 1994)
"In nineteen patients with portal hypertension and oesophageal varices, transmural variceal blood pressure was determined endoscopically by direct puncture of the varices before and after intravenous administration of 20 mg metoclopramide or placebo."5.07Reduction of transmural oesophageal variceal pressure by metoclopramide. ( Fischer, G; Geigenberger, G; Kleber, G; Paumgartner, G; Sauerbruch, T, 1991)
"We examined the preventive effect of metoclopramide on the development of esophageal varices in a rat model."3.69Metoclopramide inhibits development of esophageal varices in rat model. ( Hashizume, M; Ishii, T; Kitano, S; Komori, K; Ohta, M; Sugimachi, K; Tanoue, K; Ueno, K, 1994)
"The effects of metoclopramide on blood flow in portal and left gastric veins and cardiovascular haemodynamic variables were studied in 30 patients with both liver cirrhosis and oesophageal varices."3.69Portal venous blood flow unaltered in cirrhotic patients given metoclopramide injections. ( Hashizume, M; Ohta, M; Sugimachi, K; Tanoue, K; Tomikawa, M; Ueno, K, 1995)
"Our data indicate that ligation of oesophageal varices produces an early increase in lower oesophageal sphincter pressure in cirrhotic patients."2.70Early increase of lower oesophageal sphincter pressure after band ligation of oesophageal varices in cirrhotics: an intriguing phenomenon. ( Armonis, A; Avgerinos, A; Manolakopoulos, S; Papadimitriou, N; Raptis, SA; Rekoumis, G; Stefanidis, G; Viazis, N; Vlachogiannakos, J, 2002)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's15 (78.95)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avgerinos, A1
Viazis, N1
Armonis, A1
Vlachogiannakos, J1
Rekoumis, G1
Stefanidis, G1
Papadimitriou, N1
Manolakopoulos, S1
Raptis, SA1
Miskowiak, J1
Burcharth, F1
Jensen, LI1
Sarin, SK2
Saraya, A2
Ohta, M2
Hashizume, M2
Tanoue, K2
Ueno, K2
Komori, K1
Ishii, T1
Kitano, S1
Sugimachi, K2
Stanciu, C1
Cijevschi, C1
Stan, M1
Sandulescu, E1
Tomikawa, M1
Patch, D1
Burroughs, AK2
Spence, RA1
Kleber, G1
Sauerbruch, T2
Fischer, G1
Geigenberger, G1
Paumgartner, G1
Walker, S1
Gupta, IP2
Sharma, MP2
Arora, A1
Nijhawan, S1
Taranto, D1
Suozzo, R1
de Sio, I1
Romano, M1
Caporaso, N1
Del Vecchio Blanco, C1
Coltorti, M1
Hosking, SW1
Doss, W1
el-Zeiny, H1
Robinson, P1
Barsoum, MS1
Johnson, AG1

Reviews

3 reviews available for metoclopramide and Esophageal Varices

ArticleYear
Pharmacological treatment of portal hypertension.
    Progress in liver diseases, 1995, Volume: 13

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Catheterization; Clinical Trials as Topic; Diu

1995
Pharmacological treatment of acute variceal bleeding.
    Digestion, 1998, Volume: 59 Suppl 2

    Topics: Domperidone; Esophageal and Gastric Varices; Gastrointestinal Agents; Gastrointestinal Hemorrhage; H

1998
Vasoconstrictor therapy in bleeding esophageal varices.
    Hepato-gastroenterology, 1990, Volume: 37, Issue:6

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Lypre

1990

Trials

8 trials available for metoclopramide and Esophageal Varices

ArticleYear
Early increase of lower oesophageal sphincter pressure after band ligation of oesophageal varices in cirrhotics: an intriguing phenomenon.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:12

    Topics: Esophageal and Gastric Varices; Esophagogastric Junction; Female; Fibrosis; Humans; Ligation; Male;

2002
Effects of intravenous nitroglycerin and nitroglycerin and metoclopramide on intravariceal pressure: a double blind, randomized study.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Esophageal and Ga

1995
Effects of intravenous nitroglycerin and metoclopramide on intravariceal pressure: a double-blind, randomized study.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:11

    Topics: Adult; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Humans; Hyperten

1993
Reduction of transmural oesophageal variceal pressure by metoclopramide.
    Journal of hepatology, 1991, Volume: 12, Issue:3

    Topics: Aged; Blood Pressure; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; H

1991
Control of variceal bleed with metoclopramide.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1991, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Blood Transfusion; Double-Blind Method; Esophageal and Gastric Varices; Female; G

1991
Control of variceal bleed by constricting esophageal sphincter with metoclopramide.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:4

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoclopramide; Randomized Cont

1990
Effect of metoclopramide on transmural oesophageal variceal pressure and portal blood flow in cirrhotic patients.
    Digestion, 1990, Volume: 47, Issue:1

    Topics: Double-Blind Method; Esophageal and Gastric Varices; Esophagogastric Junction; Female; Humans; Liver

1990
Pharmacological constriction of the lower oesophageal sphincter: a simple method of arresting variceal haemorrhage.
    Gut, 1988, Volume: 29, Issue:8

    Topics: Adult; Clinical Trials as Topic; Constriction; Esophageal and Gastric Varices; Esophagogastric Junct

1988

Other Studies

8 other studies available for metoclopramide and Esophageal Varices

ArticleYear
Effect of lower oesophageal sphincter on oesophageal varices. A portographic study.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:7

    Topics: Butylscopolammonium Bromide; Depression, Chemical; Esophageal and Gastric Varices; Esophagogastric J

1981
Metoclopramide inhibits development of esophageal varices in rat model.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:9

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Esophageal and Gastric Varices; I

1994
Endoscopic intravascular esophageal pressure measurements in cirrhotic patients: response to metoclopramide.
    Hepato-gastroenterology, 1993, Volume: 40, Issue:2

    Topics: Blood Pressure; Esophageal and Gastric Varices; Esophagogastric Junction; Female; Gastrointestinal H

1993
Portal venous blood flow unaltered in cirrhotic patients given metoclopramide injections.
    The Italian journal of gastroenterology, 1995, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Case-Control Studies; Double-Blind Method; Esop

1995
Does metoclopramide reduce variceal pressure?
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1992, Volume: 5, Issue:4

    Topics: Blood Pressure; Esophageal and Gastric Varices; Esophagus; Humans; Metoclopramide; Pressure

1992
Metoclopramide in variceal bleeding.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1991, Volume: 10, Issue:2

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoclopramide

1991
Non-surgical treatment of acute upper gastrointestinal haemorrhage.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:8

    Topics: Acute Disease; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoclopramide;

1990
[Commentary on an abstract. Effects of metoclopramide and domperidone on azygous venous blood flow in patients with cirrhosis and portal hypertension].
    Zeitschrift fur Gastroenterologie, 1987, Volume: 25, Issue:9

    Topics: Azygos Vein; Domperidone; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Circul

1987