metoclopramide has been researched along with Esophageal Diseases in 11 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Esophageal Diseases: Pathological processes in the ESOPHAGUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We diagnosed an esophageal hamartoma in an infant girl who had first presented when she was 8 days old with symptoms of apnea and cyanosis." | 7.76 | Esophageal hamartoma as an unusual cause of neonatal apnea and bradycardia. ( Coury, J; Steinfeld, J; Zwillenberg, D; Zwillenberg, S, 2010) |
| "This long-term study in a patient with Barrett's esophagus showed 1) that cimetidine can be effective in treating such patients; 2) the prophylactic value of multitherapy as a maintenance regimen, and 3) the importance of careful follow-up." | 5.27 | Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus. ( Avidor, I; Delpre, G; Glanz, I; Kadish, U, 1984) |
| " We diagnosed an esophageal hamartoma in an infant girl who had first presented when she was 8 days old with symptoms of apnea and cyanosis." | 3.76 | Esophageal hamartoma as an unusual cause of neonatal apnea and bradycardia. ( Coury, J; Steinfeld, J; Zwillenberg, D; Zwillenberg, S, 2010) |
| "This long-term study in a patient with Barrett's esophagus showed 1) that cimetidine can be effective in treating such patients; 2) the prophylactic value of multitherapy as a maintenance regimen, and 3) the importance of careful follow-up." | 1.27 | Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus. ( Avidor, I; Delpre, G; Glanz, I; Kadish, U, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Ho, CC | 1 |
| Su, YJ | 1 |
| Coury, J | 1 |
| Steinfeld, J | 1 |
| Zwillenberg, D | 1 |
| Zwillenberg, S | 1 |
| Barkun, AN | 1 |
| Bardou, M | 1 |
| Martel, M | 1 |
| Gralnek, IM | 1 |
| Sung, JJ | 1 |
| Daram, SR | 1 |
| Garretson, R | 1 |
| Delpre, G | 1 |
| Kadish, U | 1 |
| Glanz, I | 1 |
| Avidor, I | 1 |
| Burns, TW | 1 |
| Rösch, W | 1 |
| Geller, LI | 1 |
| Petrenko, VF | 1 |
| Samie, MR | 1 |
| Dannenhoffer, MA | 1 |
| Rozek, S | 1 |
| Bernstein, G | 1 |
| Rifkin, H | 1 |
| Phelip, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Metoclopramide Versus Placebo During Gastrojejunostomy Tube Placement for Facilitating Guidewire Advancement Through the Pylorus[NCT03331965] | Phase 2 | 110 participants (Actual) | Interventional | 2018-04-09 | Completed | ||
| Premedication With Metoclopramide in Upper Gastrointestinal Bleeds a Prospective Double Blinded Single Center Randomized Control Trial in a Small Community Hospital[NCT05746377] | Phase 4 | 60 participants (Anticipated) | Interventional | 2023-05-20 | Recruiting | ||
| A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708] | 233 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| Erythromycin Versus Gastric Lavage to Improve Quality of Endoscopic Examination in Patients With Upper Gastrointestinal Bleeding. A Prospective Randomized Trial.[NCT01716572] | Phase 3 | 122 participants (Anticipated) | Interventional | 2012-02-29 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To assess the safety of a single dose of promotility agent prior to GJ tube placement by assessing rates of adverse events in the periprocedural period in patients receiving IV metoclopramide versus placebo. (NCT03331965)
Timeframe: Up to 30 days after procedure.
| Intervention | Participants (Count of Participants) |
|---|---|
| Metoclopramide | 0 |
| Saline | 0 |
The fluoroscopy time required to advance a guidewire through the pylorus. (NCT03331965)
Timeframe: Up to 45 minutes.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 1.6 |
| Saline | 4.1 |
The total procedure Air Kerma (energy released in a unit mass of air) measured in milligray (mGy). (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | mGy (Mean) |
|---|---|
| Metoclopramide | 91 |
| Saline | 130 |
The total procedure fluoroscopy time. (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 5.8 |
| Saline | 8.8 |
The total procedure time. (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 16.4 |
| Saline | 19.9 |
Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours
| Intervention | hours (Median) |
|---|---|
| Intervention Cohort | 26.4 |
| Comparison Cohort | 28.2 |
To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital
| Intervention | percentage of subjects with PDN (Number) |
|---|---|
| Intervention Cohort | 72 |
| Comparison Cohort | 60 |
(NCT01592708)
Timeframe: 1 week post discharge
| Intervention | percentage of subjects with PDV (Number) |
|---|---|
| Intervention Cohort | 22 |
| Comparison Cohort | 29 |
End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with PON (Number) |
|---|---|
| Intervention Cohort | 24 |
| Comparison Cohort | 70 |
(NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with POV (Number) |
|---|---|
| Intervention Cohort | 11 |
| Comparison Cohort | 28 |
1 review available for metoclopramide and Esophageal Diseases
| Article | Year |
|---|---|
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
10 other studies available for metoclopramide and Esophageal Diseases
| Article | Year |
|---|---|
Esophageal Bezoar Successfully Treated by Intravenous Metoclopramide.
Topics: Aged, 80 and over; Bezoars; Dopamine D2 Receptor Antagonists; Esophageal Diseases; Female; Humans; M | 2021 |
Esophageal hamartoma as an unusual cause of neonatal apnea and bradycardia.
Topics: Anti-Ulcer Agents; Apnea; Bradycardia; Esophageal Diseases; Female; Gastroesophageal Reflux; Hamarto | 2010 |
Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding.
Topics: Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esophageal Diseases; Gastrointestinal | 2011 |
Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus.
Topics: Aged; Aluminum Hydroxide; Barrett Esophagus; Cimetidine; Drug Combinations; Drug Therapy, Combinatio | 1984 |
Motor disorders of the esophagus: diagnosis and treatment.
Topics: Bethanechol Compounds; Calcium Channel Blockers; Esophageal Achalasia; Esophageal Diseases; Esophagi | 1984 |
[Functional disorders of the esophagus. Diagnosis and therapy].
Topics: Antacids; Collagen Diseases; Deglutition Disorders; Dietary Proteins; Esophageal Achalasia; Esophage | 1979 |
[Disorders of esophageal motility as a cause of retrosternal pain].
Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M | 1986 |
Life-threatening tardive dyskinesia caused by metoclopramide.
Topics: Aged; Dyskinesia, Drug-Induced; Esophageal Diseases; Humans; Male; Metoclopramide; Respiration Disor | 1987 |
Diabetes mellitus: gastrointestinal complications.
Topics: Blood Glucose; Cholecystitis; Cholelithiasis; Diabetes Complications; Diabetic Neuropathies; Esophag | 1986 |
[Primperan and digestive disorders in aged subjects].
Topics: Aged; Esophageal Diseases; Humans; Metoclopramide; Stomach Diseases | 1985 |