Page last updated: 2024-10-31

metoclopramide and Dysphagia

metoclopramide has been researched along with Dysphagia in 14 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"To establish a "one-stop" dysphagia service in which a consultation, barium swallow and endoscopy can all be performed in the same hospital visit."5.31Clearance of barium from the oesophagus with diet cola and metoclopramide: a one stop approach to patients with dysphagia. ( Dalton, HR; Farrow, R; Hussaini, SH; Mitchell, J, 2001)
"Oral tablet formulations of metoclopramide are effective therapies for gastroparesis and gastro-oesophageal reflux disease; however, difficulty swallowing tablets or nausea/vomiting may reduce patient adherence to therapy."5.14Pharmacokinetic comparison of orally-disintegrating metoclopramide with conventional metoclopramide tablet formulation in healthy volunteers. ( Fass, R; Pieniaszek, HJ; Thompson, JR, 2009)
" Submissions related to metoclopramide by far exceeded reports about other agents and mostly described tardive dyskinesia or other neurological concerns."3.85From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis. ( Bielefeldt, K, 2017)
"Treatments provided to improve dysphagia are aimed at accelerating recovery of swallowing function and reducing these risks."2.58Swallowing therapy for dysphagia in acute and subacute stroke. ( Bath, PM; Everton, LF; Lee, HS, 2018)
"To establish a "one-stop" dysphagia service in which a consultation, barium swallow and endoscopy can all be performed in the same hospital visit."1.31Clearance of barium from the oesophagus with diet cola and metoclopramide: a one stop approach to patients with dysphagia. ( Dalton, HR; Farrow, R; Hussaini, SH; Mitchell, J, 2001)
"The relationship between gastroesophageal reflux disease and these symptoms has been studied but remains unclear."1.29Role of gastroesophageal reflux disease in patients with cervical symptoms. ( Freeman, J; Goldberg, M; Mendelsohn, M; Rival, R; Rosgen, S; Wong, R, 1995)
"After excluding other causes of dysphagia, conservative treatment is indicated in the initial management of this disorder and should relieve symptoms in the majority of patients."1.29DISH syndrome and its role in dysphagia. ( Cravens, RB; Kmucha, ST, 1994)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bielefeldt, K1
Bath, PM1
Lee, HS1
Everton, LF1
Fass, R1
Pieniaszek, HJ1
Thompson, JR1
Gorelik, AR1
Williams, LS1
Steward, JT1
Lux, G1
Rösch, W2
Rival, R1
Wong, R1
Mendelsohn, M1
Rosgen, S1
Goldberg, M1
Freeman, J1
Kmucha, ST1
Cravens, RB1
McDougall, NI1
Johnston, BT1
Kee, F1
Collins, JS1
McFarland, RJ1
Love, AH1
Mitchell, J1
Farrow, R1
Hussaini, SH1
Dalton, HR1
Pelemans, W1
Vantrappen, G1
Plage, HJ1
Tenhonsel, G1
Bingham, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
Impact of Weight Loss on Gastroesophageal Reflux Disease in Overweight and Obese Subjects: a Prospective Study[NCT01574573]52 participants (Actual)Interventional2009-06-30Terminated (stopped due to Closed due to lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for metoclopramide and Dysphagia

ArticleYear
Swallowing therapy for dysphagia in acute and subacute stroke.
    The Cochrane database of systematic reviews, 2018, 10-30, Volume: 10

    Topics: Acupuncture Therapy; Acute Disease; Deglutition; Deglutition Disorders; Electric Stimulation Therapy

2018
Oesophageal disease in the elderly.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:4

    Topics: Age Factors; Aged; Alginates; Aluminum Hydroxide; Bethanechol Compounds; Bicarbonates; Deglutition D

1985

Trials

1 trial available for metoclopramide and Dysphagia

ArticleYear
Pharmacokinetic comparison of orally-disintegrating metoclopramide with conventional metoclopramide tablet formulation in healthy volunteers.
    Alimentary pharmacology & therapeutics, 2009, Volume: 30, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Cross-Over Studies; Deglutition Disorders; Female; Gastroes

2009

Other Studies

11 other studies available for metoclopramide and Dysphagia

ArticleYear
From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis.
    Digestive diseases and sciences, 2017, Volume: 62, Issue:11

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Antiemetics; Databases, Factual; Deglutition D

2017
Failure to thrive related to metoclopramide therapy.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antiemetics; Deglutition Disorders; Female; Hum

2003
Reader calls attention to another cause of dysphagia.
    RN, 2006, Volume: 69, Issue:10

    Topics: Aged; Antiemetics; Deglutition Disorders; Gastrectomy; Humans; Male; Metoclopramide; Postoperative C

2006
[Drug therapy of gastrointestinal motility disorders].
    Fortschritte der Medizin, 1980, Aug-21, Volume: 98, Issue:30-31

    Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Du

1980
Role of gastroesophageal reflux disease in patients with cervical symptoms.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 113, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Barium Sulfate; Biopsy; Cineradiograp

1995
DISH syndrome and its role in dysphagia.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1994, Volume: 110, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Barium Sulfate; Cineradiogra

1994
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Barrett Esophagus; Cisapride; Deglutition Disorders; Disea

1996
Clearance of barium from the oesophagus with diet cola and metoclopramide: a one stop approach to patients with dysphagia.
    Clinical radiology, 2001, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Barium Sulfate; Carbonated Beverages; Contrast Medi

2001
[Functional disorders of the esophagus. Diagnosis and therapy].
    Fortschritte der Medizin, 1979, Jan-25, Volume: 97, Issue:4

    Topics: Antacids; Collagen Diseases; Deglutition Disorders; Dietary Proteins; Esophageal Achalasia; Esophage

1979
[Oesophageal stenosis in hereditary epidermolysis bullosa (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1974, Volume: 53, Issue:8

    Topics: Child; Child, Preschool; Deglutition Disorders; Epidermolysis Bullosa; Esophageal Stenosis; Esophago

1974
Evolution and early results of constructing an anti-reflux valve in the stomach.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Barium Sulfate; Deglutition Disorders; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Metho

1974