metoclopramide has been researched along with Duodenal Diseases in 7 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gallstone dyspepsia is essentially a functional disease--a disorder of gastroduodenal motility." | 1.25 | Cholecystectomy and gallstone dyspepsia. Clinical and physiological study of a symptom complex. ( Johnson, AG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barkun, AN | 1 |
| Bardou, M | 1 |
| Martel, M | 1 |
| Gralnek, IM | 1 |
| Sung, JJ | 1 |
| Daram, SR | 1 |
| Garretson, R | 1 |
| Butvin, GK | 1 |
| Zaĭdman, VE | 1 |
| Moldovan, VI | 1 |
| Pecheniuk, VN | 1 |
| Geller, LI | 1 |
| Petrenko, VF | 1 |
| Johnson, AG | 1 |
| Conrad, G | 1 |
| Schmidt, R | 1 |
| Reshetilov, IuI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Metoclopramide Versus Placebo During Gastrojejunostomy Tube Placement for Facilitating Guidewire Advancement Through the Pylorus[NCT03331965] | Phase 2 | 110 participants (Actual) | Interventional | 2018-04-09 | Completed | ||
| Premedication With Metoclopramide in Upper Gastrointestinal Bleeds a Prospective Double Blinded Single Center Randomized Control Trial in a Small Community Hospital[NCT05746377] | Phase 4 | 60 participants (Anticipated) | Interventional | 2023-05-20 | Recruiting | ||
| A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708] | 233 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| Erythromycin Versus Gastric Lavage to Improve Quality of Endoscopic Examination in Patients With Upper Gastrointestinal Bleeding. A Prospective Randomized Trial.[NCT01716572] | Phase 3 | 122 participants (Anticipated) | Interventional | 2012-02-29 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To assess the safety of a single dose of promotility agent prior to GJ tube placement by assessing rates of adverse events in the periprocedural period in patients receiving IV metoclopramide versus placebo. (NCT03331965)
Timeframe: Up to 30 days after procedure.
| Intervention | Participants (Count of Participants) |
|---|---|
| Metoclopramide | 0 |
| Saline | 0 |
The fluoroscopy time required to advance a guidewire through the pylorus. (NCT03331965)
Timeframe: Up to 45 minutes.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 1.6 |
| Saline | 4.1 |
The total procedure Air Kerma (energy released in a unit mass of air) measured in milligray (mGy). (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | mGy (Mean) |
|---|---|
| Metoclopramide | 91 |
| Saline | 130 |
The total procedure fluoroscopy time. (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 5.8 |
| Saline | 8.8 |
The total procedure time. (NCT03331965)
Timeframe: Up to 1 hour.
| Intervention | Minutes (Mean) |
|---|---|
| Metoclopramide | 16.4 |
| Saline | 19.9 |
Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours
| Intervention | hours (Median) |
|---|---|
| Intervention Cohort | 26.4 |
| Comparison Cohort | 28.2 |
To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital
| Intervention | percentage of subjects with PDN (Number) |
|---|---|
| Intervention Cohort | 72 |
| Comparison Cohort | 60 |
(NCT01592708)
Timeframe: 1 week post discharge
| Intervention | percentage of subjects with PDV (Number) |
|---|---|
| Intervention Cohort | 22 |
| Comparison Cohort | 29 |
End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with PON (Number) |
|---|---|
| Intervention Cohort | 24 |
| Comparison Cohort | 70 |
(NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with POV (Number) |
|---|---|
| Intervention Cohort | 11 |
| Comparison Cohort | 28 |
1 review available for metoclopramide and Duodenal Diseases
| Article | Year |
|---|---|
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
Prokinetics in acute upper GI bleeding: a meta-analysis.
Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop | 2010 |
1 trial available for metoclopramide and Duodenal Diseases
| Article | Year |
|---|---|
[Evaluation of the action of drug agents on the tonus of the lower esophageal sphincter].
Topics: Atropine; Bicarbonates; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Duodenal Disease | 1978 |
5 other studies available for metoclopramide and Duodenal Diseases
| Article | Year |
|---|---|
Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding.
Topics: Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esophageal Diseases; Gastrointestinal | 2011 |
[Use of cerucal and galanthamine in the x-ray diagnosis of stomach and duodenal diseases].
Topics: Adult; Aged; Diagnosis, Differential; Duodenal Diseases; Female; Galantamine; Humans; Male; Metoclop | 1981 |
Cholecystectomy and gallstone dyspepsia. Clinical and physiological study of a symptom complex.
Topics: Adult; Bilirubin; Cholecystectomy; Cholelithiasis; Digestive System; Duodenal Diseases; Dyspepsia; F | 1975 |
[Comparative examinations of stomach and duodenum with the use of Buscolysin and Cerucal].
Topics: Ampulla of Vater; Butylscopolammonium Bromide; Cholestasis; Duodenal Diseases; Duodenal Ulcer; Human | 1976 |
[The cerucal treatment of patients with hypomotoric gastroduodenal dyskinesias and dystonias].
Topics: Chronic Disease; Drug Evaluation; Duodenal Diseases; Duodenum; Gastrointestinal Motility; Humans; Me | 1990 |