metoclopramide has been researched along with Down Syndrome in 2 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paturi, B | 1 |
| Ryan, RM | 1 |
| Michienzi, KA | 1 |
| Lakshminrusimha, S | 1 |
| Russell, JE | 1 |
| Gedye, A | 1 |
2 other studies available for metoclopramide and Down Syndrome
| Article | Year |
|---|---|
Galactorrhea with metoclopramide use in the neonatal unit.
Topics: Abnormalities, Multiple; Down Syndrome; Ductus Arteriosus, Patent; Follow-Up Studies; Galactorrhea; | 2009 |
Self-injury, regurgitation, and antiemetics.
Topics: Adult; Domperidone; Down Syndrome; Gastroesophageal Reflux; Humans; Intellectual Disability; Male; M | 1989 |