metoclopramide has been researched along with Diarrhea in 30 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study suggests that metoclopramide may reduce the rate of pneumonia and may improve other clinical outcomes in patients with subacute stroke fed via nasogastric tube." | 9.20 | Safety and effect of metoclopramide to prevent pneumonia in patients with stroke fed via nasogastric tubes trial. ( Karunatilake, D; Lally, F; Roffe, C; Sim, J; Warusevitane, A, 2015) |
| "048) with placebo (mean = 5) than ondansetron (mean = 2) and the proportion of patients experiencing no emesis was significantly greater (P = 0." | 9.08 | Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997) |
| "We tested the safety and antiemetic effectiveness of intravenous (IV) dexamethasone (DXM) as an adjunct to high-dose IV metoclopramide (MCP) to prevent nausea and vomiting induced by high-dose cisplatin chemotherapy." | 9.05 | High-dose intravenous metoclopramide versus combination high-dose metoclopramide and intravenous dexamethasone in preventing cisplatin-induced nausea and emesis: a single-blind crossover comparison of antiemetic efficacy. ( Liponi, DF; McDermed, JE; Strum, SB, 1985) |
| "Using an original high-pressure liquid chromatographic assay, we measured serum levels of metoclopramide and defined a concentration-response relationship for metoclopramide control of cisplatin-induced emesis." | 7.67 | Optimizing metoclopramide control of cisplatin-induced emesis. ( Drayer, DE; Lewin, M; Lonski, L; Meyer, BR; Pasmantier, M; Reidenberg, MM, 1984) |
| "The authors tested the safety and efficacy of intravenous metoclopramide in the prevention of chemotherapy-induced nausea and vomiting." | 7.67 | Intravenous metoclopramide: prevention of chemotherapy-induced nausea and vomiting. A preliminary evaluation. ( McDermed, JE; Pileggi, J; Riech, LP; Strum, SB; Whitaker, H, 1984) |
| "This study suggests that metoclopramide may reduce the rate of pneumonia and may improve other clinical outcomes in patients with subacute stroke fed via nasogastric tube." | 5.20 | Safety and effect of metoclopramide to prevent pneumonia in patients with stroke fed via nasogastric tubes trial. ( Karunatilake, D; Lally, F; Roffe, C; Sim, J; Warusevitane, A, 2015) |
| "048) with placebo (mean = 5) than ondansetron (mean = 2) and the proportion of patients experiencing no emesis was significantly greater (P = 0." | 5.08 | Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997) |
| " One of these agents, batanopride, produced no severe toxicity at doses that prevented emesis due to chemotherapy in early Phase I trials." | 5.07 | A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy. ( Findlay, B; Kaizer, L; Laberge, F; Latreille, J; Lofters, WS; Osoba, D; Pater, J; Rusthoven, J; Warr, D; Wilson, K, 1991) |
| " Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0." | 5.05 | Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020) |
| "We tested the safety and antiemetic effectiveness of intravenous (IV) dexamethasone (DXM) as an adjunct to high-dose IV metoclopramide (MCP) to prevent nausea and vomiting induced by high-dose cisplatin chemotherapy." | 5.05 | High-dose intravenous metoclopramide versus combination high-dose metoclopramide and intravenous dexamethasone in preventing cisplatin-induced nausea and emesis: a single-blind crossover comparison of antiemetic efficacy. ( Liponi, DF; McDermed, JE; Strum, SB, 1985) |
| " A third drug, lactulose (useful in treating hepatic encephalopathy), will soon be available." | 4.75 | Some aspects of medical management of gastrointestinal disease. I. ( Badley, BW, 1975) |
| "Using an original high-pressure liquid chromatographic assay, we measured serum levels of metoclopramide and defined a concentration-response relationship for metoclopramide control of cisplatin-induced emesis." | 3.67 | Optimizing metoclopramide control of cisplatin-induced emesis. ( Drayer, DE; Lewin, M; Lonski, L; Meyer, BR; Pasmantier, M; Reidenberg, MM, 1984) |
| "The authors tested the safety and efficacy of intravenous metoclopramide in the prevention of chemotherapy-induced nausea and vomiting." | 3.67 | Intravenous metoclopramide: prevention of chemotherapy-induced nausea and vomiting. A preliminary evaluation. ( McDermed, JE; Pileggi, J; Riech, LP; Strum, SB; Whitaker, H, 1984) |
| "Thirty-two patients with primary lung cancer receiving combination chemotherapy including cisplatin at a dosage of 80-120 mg/m2 were entered into an antiemetic randomized crossover trial." | 2.66 | [Antiemetic effects of combinations of metoclopramide, droperidol and dexamethasone for the prevention of cisplatin-induced gastro-intestinal toxicity: a randomized crossover trial]. ( Fujii, M; Kamei, H; Kiura, K; Okabe, K; Toki, H, 1987) |
| "For moderate dehydration, eight CPGs advocated nasogastric (NG) rehydration in preference to intravenous (IV) rehydration." | 1.35 | Emergency department management of gastro-enteritis in Australia and New Zealand. ( Babl, FE; Borland, M; Schutz, J; Sheriff, N, 2008) |
| "His hiccups were treated with metoclopramide, but it had little effect, and hiccups only subsided gradually after the disappearance of erosions." | 1.35 | Herpes zoster laryngitis with intractable hiccups. ( Morinaka, S, 2009) |
| "Cisapride was a potent stimulant of gastric emptying in rats, 7 times more potent than metoclopramide." | 1.28 | General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride. ( Awouters, FH; Megens, AA; Niemegeers, CJ, 1991) |
| "Fabry's disease is a rare, sex-linked disorder of glycolipid metabolism." | 1.26 | Pathophysiologic and ultrastructural basis for intestinal symptoms in Fabry's disease. ( Anholt, L; Costopoulos, L; Freeman, H; Lentle, B; McDougall, R; O'Brien, BD; Shnitka, TK; Thomson, AB; Walker, K, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (56.67) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Niño-Serna, LF | 1 |
| Acosta-Reyes, J | 1 |
| Veroniki, AA | 1 |
| Florez, ID | 1 |
| Warusevitane, A | 1 |
| Karunatilake, D | 1 |
| Sim, J | 1 |
| Lally, F | 1 |
| Roffe, C | 1 |
| Lewis, K | 1 |
| Alqahtani, Z | 1 |
| Mcintyre, L | 1 |
| Almenawer, S | 1 |
| Alshamsi, F | 1 |
| Rhodes, A | 1 |
| Evans, L | 1 |
| Angus, DC | 1 |
| Alhazzani, W | 1 |
| Schutz, J | 1 |
| Babl, FE | 1 |
| Sheriff, N | 1 |
| Borland, M | 1 |
| Morinaka, S | 1 |
| Trepanier, L | 1 |
| Supariwala, A | 1 |
| Kant, G | 1 |
| Jean, RE | 1 |
| Hansen, W | 1 |
| Feldman, M | 1 |
| Schiller, LR | 1 |
| Meyer, BR | 1 |
| Lewin, M | 1 |
| Drayer, DE | 1 |
| Pasmantier, M | 1 |
| Lonski, L | 1 |
| Reidenberg, MM | 1 |
| Strum, SB | 2 |
| McDermed, JE | 2 |
| Pileggi, J | 1 |
| Riech, LP | 1 |
| Whitaker, H | 1 |
| O'Brien, BD | 1 |
| Shnitka, TK | 1 |
| McDougall, R | 1 |
| Walker, K | 1 |
| Costopoulos, L | 1 |
| Lentle, B | 1 |
| Anholt, L | 1 |
| Freeman, H | 1 |
| Thomson, AB | 1 |
| Long, RG | 1 |
| Bryant, MG | 1 |
| Yuille, PM | 1 |
| Polak, JM | 1 |
| Bloom, SR | 1 |
| Lux, G | 1 |
| Rösch, W | 1 |
| Cubeddu, LX | 1 |
| Trujillo, LM | 1 |
| Talmaciu, I | 1 |
| Gonzalez, V | 1 |
| Guariguata, J | 1 |
| Seijas, J | 1 |
| Miller, IA | 1 |
| Paska, W | 1 |
| Khoo, VS | 1 |
| Rainford, K | 1 |
| Horwich, A | 1 |
| Dearnaley, DP | 1 |
| Sinha, PK | 1 |
| Tripathi, M | 1 |
| Ambesh, SP | 1 |
| Badley, BW | 1 |
| Wright, RA | 1 |
| MacGregor, IL | 1 |
| Waller, SL | 1 |
| Rusthoven, J | 1 |
| Pater, J | 1 |
| Kaizer, L | 1 |
| Wilson, K | 1 |
| Osoba, D | 1 |
| Latreille, J | 1 |
| Findlay, B | 1 |
| Lofters, WS | 1 |
| Warr, D | 1 |
| Laberge, F | 1 |
| Megens, AA | 1 |
| Awouters, FH | 1 |
| Niemegeers, CJ | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Tochner, ZA | 1 |
| Kinsella, TJ | 1 |
| Glatstein, E | 1 |
| Fujii, M | 1 |
| Kiura, K | 1 |
| Kamei, H | 1 |
| Okabe, K | 1 |
| Toki, H | 1 |
| McGrew, W | 1 |
| Patel, J | 1 |
| Miller, P | 1 |
| Liponi, DF | 1 |
| Gez, E | 1 |
| Catane, R | 1 |
| Pfau, L | 1 |
| Biran, S | 1 |
| Masterton, G | 1 |
| Schofield, CB | 1 |
| Tait, IB | 1 |
| Palmer, HM | 1 |
| Beardwell, CG | 1 |
6 reviews available for metoclopramide and Diarrhea
| Article | Year |
|---|---|
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper | 2020 |
The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.
Topics: Chi-Square Distribution; Critical Illness; Diarrhea; Domperidone; Dopamine Antagonists; Enteral Nutr | 2016 |
Acute vomiting in cats: rational treatment selection.
Topics: Acute Disease; Animals; Antiemetics; Cat Diseases; Cats; Chlorpromazine; Diarrhea; Famotidine; Indol | 2010 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; | 1980 |
Disorders of gastrointestinal motility associated with diabetes mellitus.
Topics: Autonomic Nervous System Diseases; Bethanechol Compounds; Constipation; Diabetes Complications; Diab | 1983 |
Some aspects of medical management of gastrointestinal disease. I.
Topics: Diarrhea; Disaccharides; Endoscopy; Esophagitis; Gastric Juice; Gastric Mucosa; Gastrointestinal Dis | 1975 |
7 trials available for metoclopramide and Diarrhea
| Article | Year |
|---|---|
Safety and effect of metoclopramide to prevent pneumonia in patients with stroke fed via nasogastric tubes trial.
Topics: Aged; Aged, 80 and over; Diarrhea; Dopamine D2 Receptor Antagonists; Double-Blind Method; Female; Fo | 2015 |
Antiemetic activity of ondansetron in acute gastroenteritis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Diarrhea; Female; Fluid Therapy; Gastroenteriti | 1997 |
The effect of antiemetics and reduced radiation fields on acute gastrointestinal morbidity of adjuvant radiotherapy in stage I seminoma of the testis: a randomized pilot study.
Topics: Acute Disease; Adult; Antiemetics; Diarrhea; Gastrointestinal Diseases; Humans; Lymphatic Metastasis | 1997 |
Efficacy of ondansetron in prophylaxis of postoperative nausea and vomiting in patients following infratentorial surgery: a placebo-controlled prospective double-blind study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Antiemetics; Cerebellum; Consciousness; Diarrhea; Dou | 1999 |
A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy.
Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Diarrhea; Dose-Response Relationship, Drug; D | 1991 |
[Antiemetic effects of combinations of metoclopramide, droperidol and dexamethasone for the prevention of cisplatin-induced gastro-intestinal toxicity: a randomized crossover trial].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as | 1987 |
High-dose intravenous metoclopramide versus combination high-dose metoclopramide and intravenous dexamethasone in preventing cisplatin-induced nausea and emesis: a single-blind crossover comparison of antiemetic efficacy.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; | 1985 |
17 other studies available for metoclopramide and Diarrhea
| Article | Year |
|---|---|
Emergency department management of gastro-enteritis in Australia and New Zealand.
Topics: Acute Disease; Antiemetics; Australia; Data Collection; Dehydration; Diarrhea; Emergency Medicine; E | 2008 |
Herpes zoster laryngitis with intractable hiccups.
Topics: Acyclovir; Administration, Oral; Aged; Anti-Inflammatory Agents; Antiviral Agents; Diarrhea; Edema; | 2009 |
Neuroleptic malignant syndrome with metoclopramide overdose coexisting with Clostridium difficile diarrhea.
Topics: Diarrhea; Dopamine Antagonists; Enterocolitis, Pseudomembranous; Humans; Male; Metoclopramide; Middl | 2011 |
Optimizing metoclopramide control of cisplatin-induced emesis.
Topics: Adult; Aged; Body Weight; Chromatography, High Pressure Liquid; Cisplatin; Diarrhea; Drug Administra | 1984 |
Intravenous metoclopramide: prevention of chemotherapy-induced nausea and vomiting. A preliminary evaluation.
Topics: Antineoplastic Agents; Diarrhea; Drug Administration Schedule; Drug Evaluation; Humans; Infusions, P | 1984 |
Pathophysiologic and ultrastructural basis for intestinal symptoms in Fabry's disease.
Topics: Adult; Bile; Biopsy; Cholelithiasis; Diarrhea; Fabry Disease; Gastric Emptying; Humans; Jejunum; Mal | 1982 |
Mixed pancreatic apudoma with symptoms of excess vasoactive intestinal polypeptide and insulin: improvement of diarrhoea with metoclopramide.
Topics: Apudoma; Diarrhea; Female; Gastrointestinal Hormones; Humans; Insulin; Insulin Secretion; Metoclopra | 1981 |
[Drug therapy of gastrointestinal motility disorders].
Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Du | 1980 |
Effect of metoclopramide on gastric stasis after reversed jejunal loop for postvagotomy diarrhea.
Topics: Adult; Diarrhea; Dumping Syndrome; Gastric Emptying; Humans; Jejunum; Male; Metoclopramide; Postoper | 1979 |
Differential measurement of small and large bowel transit times in constipation and diarrhoea: A new approach.
Topics: Adult; Capsules; Cathartics; Codeine; Colon; Constipation; Diarrhea; Female; Gastrointestinal Motili | 1975 |
General pharmacology of the four gastrointestinal motility stimulants bethanechol, metoclopramide, trimebutine, and cisapride.
Topics: Animals; Apomorphine; Bethanechol Compounds; Cisapride; Conditioning, Operant; Diarrhea; Dogs; Gastr | 1991 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Hepatic irradiation in the management of metastatic hormone-secreting tumors.
Topics: Adenoma, Islet Cell; Adult; Diarrhea; Female; Hemangiopericytoma; Humans; Laparotomy; Liver Neoplasm | 1985 |
Jejunal diverticulosis: medical and surgical management.
Topics: Aged; Anemia; Antacids; Diagnosis, Differential; Diarrhea; Diverticulum; Humans; Jejunal Diseases; M | 1985 |
High-dose metoclopramide as an antiemetic in patients receiving cis-platinum-based combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diarrhea; Female; Humans; Male; Metoclopr | 1985 |
Triple tetracycline ('Deteclo') as a single dose oral treatment of uncomplicated gonorrhoea in the male.
Topics: Administration, Oral; Adolescent; Adult; Chlortetracycline; Demeclocycline; Diarrhea; Drug Combinati | 1973 |
Hyperthyroidism presenting with acute abdominal symptoms.
Topics: Abdomen, Acute; Adult; Antacids; Body Weight; Carbimazole; Colic; Diarrhea; Female; Goiter; Hemateme | 1974 |