metoclopramide has been researched along with Death, Sudden, Cardiac in 5 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of two large epidemiological studies on the association between domperidone and ventricular arrhythmia or sudden cardiac death were published in 2015; one study was conducted in Taiwan and the other in the United Kingdom." | 7.83 | Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia. ( , 2016) |
| "We aimed to examine the association between cisapride and ventricular arrhythmia, and examine the relationship to dose and CYP3A4 inhibitors." | 7.74 | Cisapride and ventricular arrhythmia. ( Bilker, WB; Hennessy, S; Kimmel, SE; Leonard, CE; Newcomb, C, 2008) |
| " From these publications, it cannot be concluded that domperidone exposure definitely increases the risk of "sudden cardiac death", "death associated with ventricular arrhythmia" or "ventricular arrhythmia" The most concrete result of these studies is that the risk is higher with metoclopramide exposure compared to domperidone exposure." | 5.01 | Critical review of European Medicines Agency (EMA) assessment report and related literature on domperidone. ( Tuğlular, I; Yüksel, K, 2019) |
| "The results of two large epidemiological studies on the association between domperidone and ventricular arrhythmia or sudden cardiac death were published in 2015; one study was conducted in Taiwan and the other in the United Kingdom." | 3.83 | Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia. ( , 2016) |
| "We aimed to examine the association between cisapride and ventricular arrhythmia, and examine the relationship to dose and CYP3A4 inhibitors." | 3.74 | Cisapride and ventricular arrhythmia. ( Bilker, WB; Hennessy, S; Kimmel, SE; Leonard, CE; Newcomb, C, 2008) |
| "Out-of-hospital sudden cardiac death was assessed by linkage with Hospital Episode Statistics and death certificates." | 1.42 | Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study. ( Arana, A; Fife, D; Johannes, CB; McQuay, LJ; Rothman, KJ; Varas-Lorenzo, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yüksel, K | 1 |
| Tuğlular, I | 1 |
| Arana, A | 1 |
| Johannes, CB | 1 |
| McQuay, LJ | 1 |
| Varas-Lorenzo, C | 1 |
| Fife, D | 1 |
| Rothman, KJ | 1 |
| Hennessy, S | 2 |
| Leonard, CE | 2 |
| Palumbo, CM | 1 |
| Bilker, WB | 2 |
| Newcomb, C | 2 |
| Kimmel, SE | 2 |
1 review available for metoclopramide and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Critical review of European Medicines Agency (EMA) assessment report and related literature on domperidone.
Topics: Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Humans; Metoclopramide; Risk | 2019 |
4 other studies available for metoclopramide and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia.
Topics: Antiemetics; Arrhythmias, Cardiac; Clinical Decision-Making; Death, Sudden, Cardiac; Domperidone; Do | 2016 |
Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study.
Topics: Aging; Antiemetics; Case-Control Studies; Death, Sudden, Cardiac; Domperidone; Dose-Response Relatio | 2015 |
Diagnostic codes for sudden cardiac death and ventricular arrhythmia functioned poorly to identify outpatient events in EPIC's General Practice Research Database.
Topics: Arrhythmias, Cardiac; Cisapride; Cohort Studies; Databases, Factual; Death, Sudden, Cardiac; Domperi | 2008 |
Cisapride and ventricular arrhythmia.
Topics: Adult; Aged; Arrhythmias, Cardiac; Case-Control Studies; Cisapride; Cytochrome P-450 CYP3A; Death, S | 2008 |