metoclopramide has been researched along with Constipation in 14 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral granisetron alone was as effective as met/dex in control of acute emesis in all parameters examined." | 9.07 | Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group. ( Cedar, E; Cunningham, J; Goedhals, L; Heron, JF; Jordaan, JP, 1994) |
| " A sample of 43 patients with breast cancer was accrued from September to November 1992 in a phase II study to assess the efficacy of granisetron in patients receiving FEC (5-FU, epirubicin, cyclophosphamide)." | 9.07 | Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide. ( Ang, PT; Khoo, KS; Tan, EH, 1994) |
| "There is no approved protocol for vincristine-induced autonomic neuropathy treatment; thus, prokinetic agents such as metoclopramide can be considered as an option for ileus treatment after ruling out the possibility of bowel obstruction." | 7.91 | Treatment of vincristine-induced ileus with metoclopramide: A case report. ( Ghavamzadeh, A; Hadjibabaie, M; Khajeh, B; Masoumi, HT; Zarif-Yeganeh, M, 2019) |
| "A case of prolonged encephalopathy and worsened parkinsonism in a Parkinson disease patient exposed to a short course of metoclopramide is described." | 7.76 | Metoclopramide-induced encephalopathy in Parkinson disease. ( Anderson, KE; Robottom, BJ; Shulman, LM; Weiner, WJ, 2010) |
| " Oral granisetron alone was as effective as met/dex in control of acute emesis in all parameters examined." | 5.07 | Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group. ( Cedar, E; Cunningham, J; Goedhals, L; Heron, JF; Jordaan, JP, 1994) |
| " A sample of 43 patients with breast cancer was accrued from September to November 1992 in a phase II study to assess the efficacy of granisetron in patients receiving FEC (5-FU, epirubicin, cyclophosphamide)." | 5.07 | Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide. ( Ang, PT; Khoo, KS; Tan, EH, 1994) |
| "There is no approved protocol for vincristine-induced autonomic neuropathy treatment; thus, prokinetic agents such as metoclopramide can be considered as an option for ileus treatment after ruling out the possibility of bowel obstruction." | 3.91 | Treatment of vincristine-induced ileus with metoclopramide: A case report. ( Ghavamzadeh, A; Hadjibabaie, M; Khajeh, B; Masoumi, HT; Zarif-Yeganeh, M, 2019) |
| "A case of prolonged encephalopathy and worsened parkinsonism in a Parkinson disease patient exposed to a short course of metoclopramide is described." | 3.76 | Metoclopramide-induced encephalopathy in Parkinson disease. ( Anderson, KE; Robottom, BJ; Shulman, LM; Weiner, WJ, 2010) |
| "Biopsy revealed a pulmonary squamous cell carcinoma, which was inoperable." | 1.62 | Gastrointestinal dysmotility in a patient with advanced lung cancer: paraneoplastic or drug-induced? ( Dias, RF; Diniz, MML; Nobre, VA; Santos, BC, 2021) |
| " Using a Delphi study method, physicians were asked to rank preferences of drug and dosing schedule for first-line opioid, antiemetic, and laxative for the treatment of adults with chronic pain due to cancer and other life-threatening conditions." | 1.38 | Strategic pain management: the identification and development of the IAHPC opioid essential prescription package. ( Bennett, MI; Bruera, E; De Lima, L; Nekolaichuk, C; Ripamonti, CI; Vignaroli, E; Wenk, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Gudsoorkar, V | 1 |
| Quigley, EMM | 1 |
| Dias, RF | 1 |
| Diniz, MML | 1 |
| Santos, BC | 1 |
| Nobre, VA | 1 |
| Masoumi, HT | 1 |
| Hadjibabaie, M | 1 |
| Zarif-Yeganeh, M | 1 |
| Khajeh, B | 1 |
| Ghavamzadeh, A | 1 |
| Robottom, BJ | 1 |
| Shulman, LM | 1 |
| Anderson, KE | 1 |
| Weiner, WJ | 1 |
| Vignaroli, E | 1 |
| Bennett, MI | 1 |
| Nekolaichuk, C | 1 |
| De Lima, L | 1 |
| Wenk, R | 1 |
| Ripamonti, CI | 1 |
| Bruera, E | 1 |
| Hansen, W | 1 |
| Feldman, M | 1 |
| Schiller, LR | 1 |
| Battle, WM | 1 |
| Snape, WJ | 1 |
| Alavi, A | 1 |
| Cohen, S | 1 |
| Braunstein, S | 1 |
| Heron, JF | 1 |
| Goedhals, L | 1 |
| Jordaan, JP | 1 |
| Cunningham, J | 1 |
| Cedar, E | 1 |
| Tan, EH | 1 |
| Ang, PT | 1 |
| Khoo, KS | 1 |
| Mukand, JA | 1 |
| Kaplan, MS | 1 |
| Blackinton, DD | 1 |
| Biener-Bergman, S | 1 |
| Trojan, DA | 1 |
| Waller, SL | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Garewal, HS | 1 |
| Dalton, WS | 1 |
3 reviews available for metoclopramide and Constipation
| Article | Year |
|---|---|
Choosing a Prokinetic for Your Patient Beyond Metoclopramide.
Topics: Constipation; Dopamine D2 Receptor Antagonists; Dyspepsia; Gastric Emptying; Gastrointestinal Motili | 2020 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; | 1980 |
Disorders of gastrointestinal motility associated with diabetes mellitus.
Topics: Autonomic Nervous System Diseases; Bethanechol Compounds; Constipation; Diabetes Complications; Diab | 1983 |
2 trials available for metoclopramide and Constipation
| Article | Year |
|---|---|
Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group.
Topics: Administration, Oral; Adult; Aged; Chi-Square Distribution; Cisplatin; Constipation; Dexamethasone; | 1994 |
Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Constipation; Cyclophosphamide; Epirubicin; Fem | 1994 |
9 other studies available for metoclopramide and Constipation
| Article | Year |
|---|---|
Gastrointestinal dysmotility in a patient with advanced lung cancer: paraneoplastic or drug-induced?
Topics: Aged; Antiemetics; Carcinoma, Squamous Cell; Constipation; Gastrointestinal Agents; Gastrointestinal | 2021 |
Treatment of vincristine-induced ileus with metoclopramide: A case report.
Topics: Antineoplastic Agents, Phytogenic; Constipation; Gastrointestinal Agents; Humans; Ileus; Male; Metoc | 2019 |
Metoclopramide-induced encephalopathy in Parkinson disease.
Topics: Aged; Antiemetics; Constipation; Humans; Male; Metoclopramide; Neurotoxicity Syndromes; Parkinson Di | 2010 |
Strategic pain management: the identification and development of the IAHPC opioid essential prescription package.
Topics: Analgesics, Opioid; Antiemetics; Clinical Protocols; Constipation; Delphi Technique; Dioctyl Sulfosu | 2012 |
Colonic dysfunction in diabetes mellitus.
Topics: Action Potentials; Adolescent; Adult; Colon; Constipation; Diabetes Mellitus; Diabetes Mellitus, Typ | 1980 |
The gastric emptying scan as a tool for surgical management of severe bowel dysfunction in spinal cord injury: 2 case reports.
Topics: Antiemetics; Constipation; Gastric Emptying; Gastrointestinal Motility; Gastrostomy; Humans; Ileosto | 2000 |
Differential measurement of small and large bowel transit times in constipation and diarrhoea: A new approach.
Topics: Adult; Capsules; Cathartics; Codeine; Colon; Constipation; Diarrhea; Female; Gastrointestinal Motili | 1975 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |
Metoclopramide in vincristine-induced ileus.
Topics: Aged; Constipation; Gastrointestinal Motility; Humans; Intestinal Obstruction; Leukemia, Lymphoid; L | 1985 |