metoclopramide has been researched along with Complications, Pregnancy in 28 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 9.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "This study assesses the effects of ginger on nausea and vomiting caused by pregnancy and compares it with metoclopramide medicine." | 9.15 | Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea. ( Farhadifar, F; Mohammadbeigi, R; Rezaiie, M; Shahgeibi, S; Soufizadeh, N, 2011) |
| "To examine the medical evidence regarding the clinical efficacy and cost-effectiveness of the application of continuous subcutaneous metoclopramide and ondansetron to treat nausea and vomiting during pregnancy." | 8.88 | Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy. ( Kirkbride, MS; Reichmann, JP, 2012) |
| "In various countries, metoclopramide is the antiemetic drug of choice in pregnant women, but insufficient information exists regarding its safety in pregnancy." | 7.75 | The safety of metoclopramide use in the first trimester of pregnancy. ( Gorodischer, R; Koren, G; Levy, A; Matok, I; Sheiner, E; Wiznitzer, A, 2009) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 7.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| "The impact of hyperprolactinaemia on endometrial function, along with embryo implantation, has been the subject of discussion." | 5.33 | Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice. ( Baptista, HA; Baracat, EC; da Motta, EL; de Jesus Simões, M; Haapalainen, EF; Haidar, MA; Júnior, JM; Panzan, MQ, 2006) |
| "Metoclopramide is a dopamine receptor blocking drug that is commonly used to treat nausea and vomiting." | 5.31 | Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. ( Addis, A; Arnon, J; Berkovitch, M; Elbirt, D; Greenberg, R; Magee, L; Mazzota, P; Merlob, P; Moretti, M; Ornoy, A; Schuler-Faccini, L; Stahl, B, 2002) |
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 5.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "This study assesses the effects of ginger on nausea and vomiting caused by pregnancy and compares it with metoclopramide medicine." | 5.15 | Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea. ( Farhadifar, F; Mohammadbeigi, R; Rezaiie, M; Shahgeibi, S; Soufizadeh, N, 2011) |
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| "To examine the medical evidence regarding the clinical efficacy and cost-effectiveness of the application of continuous subcutaneous metoclopramide and ondansetron to treat nausea and vomiting during pregnancy." | 4.88 | Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy. ( Kirkbride, MS; Reichmann, JP, 2012) |
| "In various countries, metoclopramide is the antiemetic drug of choice in pregnant women, but insufficient information exists regarding its safety in pregnancy." | 3.75 | The safety of metoclopramide use in the first trimester of pregnancy. ( Gorodischer, R; Koren, G; Levy, A; Matok, I; Sheiner, E; Wiznitzer, A, 2009) |
| "A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide." | 3.67 | Acute intermittent porphyria in pregnancy. ( Arlazoroff, A; Caspi, E; Klein, C; Milo, R; Neuman, M, 1989) |
| " Her pregnancy was induced by pituitary gonadotrophins and the deficient prolactin pituitary reserve was shown by means of pituitary stimulation test with metoclopramide of pituitary stimulation test with metoclopramide and TRH." | 3.66 | Serum prolactin during pregnancy induced by pituitary gonadotrophins in a patient with post partum hypopituitarism (Sheehan syndrome). ( Lee, D; León, C; Milanés, BA, 1981) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 3.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| "Yet data are limited addressing treatment of headache in pregnancy." | 2.72 | Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review. ( Bushman, ET; Cozzi, G; Digre, K; Sinkey, RG; Smith, CH; Varner, MW, 2021) |
| "Heartburn is a normal consequence of pregnancy." | 2.43 | Review article: the management of heartburn in pregnancy. ( Richter, JE, 2005) |
| " Pyridoxine is considered safe for use during pregnancy, but its efficacy in treating nausea and vomiting has not been determined." | 2.37 | Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. ( Leathem, AM, 1986) |
| "Acetaminophen was the most frequent medicine administered first (53%, 38/72)." | 1.51 | Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. ( Hamilton, KT; Robbins, MS, 2019) |
| "The impact of hyperprolactinaemia on endometrial function, along with embryo implantation, has been the subject of discussion." | 1.33 | Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice. ( Baptista, HA; Baracat, EC; da Motta, EL; de Jesus Simões, M; Haapalainen, EF; Haidar, MA; Júnior, JM; Panzan, MQ, 2006) |
| "Metoclopramide is a dopamine receptor blocking drug that is commonly used to treat nausea and vomiting." | 1.31 | Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. ( Addis, A; Arnon, J; Berkovitch, M; Elbirt, D; Greenberg, R; Magee, L; Mazzota, P; Merlob, P; Moretti, M; Ornoy, A; Schuler-Faccini, L; Stahl, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (46.43) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bushman, ET | 1 |
| Cozzi, G | 1 |
| Sinkey, RG | 1 |
| Smith, CH | 1 |
| Varner, MW | 1 |
| Digre, K | 1 |
| Tan, A | 1 |
| Lowe, S | 1 |
| Henry, A | 1 |
| Childress, KMS | 1 |
| Dothager, C | 1 |
| Gavard, JA | 1 |
| Lebovitz, S | 1 |
| Laska, C | 1 |
| Mostello, DJ | 1 |
| Hamilton, KT | 1 |
| Robbins, MS | 1 |
| Hastoy, A | 1 |
| Lien Tran, P | 1 |
| Lakestani, O | 1 |
| Barau, G | 1 |
| Gérardin, P | 1 |
| Boukerrou, M | 1 |
| Jarraya, A | 1 |
| Elleuch, S | 1 |
| Zouari, J | 1 |
| Trigui, K | 1 |
| Sofiene, A | 1 |
| Smaoui, M | 1 |
| Kolsi, K | 1 |
| Matok, I | 1 |
| Gorodischer, R | 1 |
| Koren, G | 1 |
| Sheiner, E | 1 |
| Wiznitzer, A | 1 |
| Levy, A | 1 |
| Mohammadbeigi, R | 1 |
| Shahgeibi, S | 1 |
| Soufizadeh, N | 1 |
| Rezaiie, M | 1 |
| Farhadifar, F | 1 |
| Reichmann, JP | 1 |
| Kirkbride, MS | 1 |
| Berkovitch, M | 1 |
| Mazzota, P | 1 |
| Greenberg, R | 1 |
| Elbirt, D | 1 |
| Addis, A | 1 |
| Schuler-Faccini, L | 1 |
| Merlob, P | 1 |
| Arnon, J | 1 |
| Stahl, B | 1 |
| Magee, L | 1 |
| Moretti, M | 1 |
| Ornoy, A | 1 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| Richter, JE | 1 |
| Buscaglia, J | 1 |
| Faris, J | 1 |
| Panzan, MQ | 1 |
| Júnior, JM | 1 |
| da Motta, EL | 1 |
| Haapalainen, EF | 1 |
| de Jesus Simões, M | 1 |
| Baptista, HA | 1 |
| Haidar, MA | 1 |
| Baracat, EC | 1 |
| Lee, D | 1 |
| León, C | 1 |
| Milanés, BA | 1 |
| Gibbs, D | 1 |
| Milton-Thompson, GJ | 1 |
| Hey, VM | 2 |
| Ostick, DG | 1 |
| Paparatti, L | 1 |
| Mancuso, S | 1 |
| Askenasy, JJ | 1 |
| Streifler, M | 1 |
| Felner, S | 1 |
| Brock-Utne, JG | 1 |
| Dow, TG | 1 |
| Welman, S | 1 |
| Dimopoulos, GE | 1 |
| Moshal, MG | 1 |
| Braun, U | 1 |
| Steiner, A | 1 |
| Kaegi, B | 1 |
| Lewis, JH | 1 |
| Weingold, AB | 1 |
| Leathem, AM | 1 |
| Howden, CW | 1 |
| Milo, R | 1 |
| Neuman, M | 1 |
| Klein, C | 1 |
| Caspi, E | 1 |
| Arlazoroff, A | 1 |
| Saad Zoi, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy of Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy : A Randomized Double-Blind Controlled Trial[NCT02470117] | Phase 4 | 100 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for metoclopramide and Complications, Pregnancy
| Article | Year |
|---|---|
Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review.
Topics: Acupuncture Analgesia; Analgesics; Biofeedback, Psychology; Codeine; Complementary Therapies; Diphen | 2021 |
Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy.
Topics: Antiemetics; Evidence-Based Medicine; Female; Humans; Infusions, Subcutaneous; Metoclopramide; Nause | 2012 |
Review article: the management of heartburn in pregnancy.
Topics: Antacids; Anti-Ulcer Agents; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Motility; | 2005 |
The use of gastrointestinal drugs during pregnancy and lactation.
Topics: Adrenal Cortex Hormones; Animals; Antidiarrheals; Antiemetics; Cathartics; Diuretics; Female; Gastro | 1985 |
Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy.
Topics: Antiemetics; Antipsychotic Agents; Dicyclomine; Diphenhydramine; Doxylamine; Drug Combinations; Fema | 1986 |
4 trials available for metoclopramide and Complications, Pregnancy
| Article | Year |
|---|---|
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug A | 2018 |
Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Metoclopramide; Nausea; Placebos; Pregnancy | 2011 |
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
Metoclopramide and the gastro-oesophageal sphincter. A study in pregnant women with heartburn.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Esophagogastric Junction; Female; | 1978 |
19 other studies available for metoclopramide and Complications, Pregnancy
| Article | Year |
|---|---|
Nausea and vomiting of pregnancy: Effects on quality of life and day-to-day function.
Topics: Activities of Daily Living; Antiemetics; Cohort Studies; Female; Humans; Hyperemesis Gravidarum; Met | 2018 |
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; H | 2019 |
[Hyperemesis gravidarum and pregnancy outcomes].
Topics: Adult; Antiemetics; Female; Hospitalization; Humans; Hyperemesis Gravidarum; Infant, Newborn; Metocl | 2015 |
[Hyperemesis gravidarum with severe electrolyte disorders: report of a case].
Topics: Acute Kidney Injury; Antiemetics; Female; Fluid Therapy; Hepatomegaly; Humans; Hyperemesis Gravidaru | 2015 |
The safety of metoclopramide use in the first trimester of pregnancy.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cohort Studies; Female; Fetus; Humans; Infant, Low Birth W | 2009 |
Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study.
Topics: Adolescent; Adult; Antiemetics; Brazil; Canada; Case-Control Studies; Congenital Abnormalities; Dopa | 2002 |
Unsteady, unfocused, and unable to hear.
Topics: Adolescent; Cognition Disorders; Combined Modality Therapy; Female; Fluid Therapy; Gait Disorders, N | 2005 |
Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice.
Topics: Animals; Disease Models, Animal; Endometrium; Female; Hyperprolactinemia; Metoclopramide; Mice; Preg | 2006 |
Serum prolactin during pregnancy induced by pituitary gonadotrophins in a patient with post partum hypopituitarism (Sheehan syndrome).
Topics: Adult; Female; Fetal Blood; Gonadotropins, Pituitary; Humans; Hypopituitarism; Infertility, Female; | 1981 |
Diseases of the alimentary system; Nausea and vomiting.
Topics: Antiemetics; Female; Histamine H1 Antagonists; Humans; Metoclopramide; Motion Sickness; Nausea; Phen | 1976 |
Anti-nauseant drugs.
Topics: Antiemetics; Antipsychotic Agents; Female; Gastrointestinal Diseases; Histamine H1 Antagonists; Huma | 1979 |
[Therapeutic experience in the treatment of some gastrointestinal disorders during pregnancy].
Topics: Adult; Antacids; Drug Combinations; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Meto | 1977 |
The synaptic significance of metoclopramide induced dyskinetic-dystonic head and neck movements in pregnancy.
Topics: Adolescent; Adult; Dyskinesia, Drug-Induced; Female; Head; Humans; Hyperemesis Gravidarum; Metoclopr | 1978 |
The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy.
Topics: Adolescent; Adult; Esophagogastric Junction; Female; Gastroesophageal Reflux; Heartburn; Humans; Met | 1978 |
Gastro-oesophageal reflux in pregnancy: a review article.
Topics: Esophagogastric Junction; Female; Gastrins; Gastroesophageal Reflux; Hernia, Hiatal; Humans; Metoclo | 1978 |
Clinical, haematological and biochemical findings and the results of treatment in cattle with acute functional pyloric stenosis.
Topics: Acute Disease; Alkalosis; Animals; Bile Acids and Salts; Cattle; Cattle Diseases; Chlorides; Female; | 1990 |
Treatment of common minor ailments.
Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonist | 1986 |
Acute intermittent porphyria in pregnancy.
Topics: Acute Disease; Adult; Diagnosis, Differential; Female; Fluid Therapy; Genes, Dominant; Humans; Hyper | 1989 |
[Primperan during pregnancy].
Topics: Female; Heartburn; Humans; Metoclopramide; Pneumonia, Aspiration; Pregnancy; Pregnancy Complications | 1985 |