metoclopramide has been researched along with Chronic Illness in 40 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The short elimination half-life of metoclopramide necessitates frequent administration for optimal relief of nausea." | 9.07 | Comparison of the efficacy, safety, and pharmacokinetics of controlled release and immediate release metoclopramide for the management of chronic nausea in patients with advanced cancer. ( Babul, N; Bruera, ED; Darke, AC; Harsanyi, Z; LeGatt, DF; MacDonald, RN; MacEachern, TJ; Spachynski, KA, 1994) |
| "A double-blind, placebo-controlled trial was performed to determine the therapeutic efficacy of cisapride in patients with refractory functional dyspepsia." | 9.07 | Efficacy of cisapride in functional dyspepsia resistant to domperidone or metoclopramide: a double-blind, placebo-controlled study. ( De Nutte, N; Gooris, JP; Van Eeghem, P; Van Outryve, M, 1993) |
| "A double-blind comparison of metoclopramide versus placebo was performed on 8 cirrhotic patients with nausea (8 cases) and heartburn (3 of the 8 cases) plus mild portal-systemic encephalopathy." | 9.05 | Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial. ( Ballesteros, A; Briones, A; Garcia Ramos, G; Garza, J; Rosales, J; Strauss, R; Uribe, M; Villalobos, A, 1985) |
| "Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn." | 9.04 | A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977) |
| "Forty-seven infants and children suffering from chronic vomiting or regurgitation, participated in a two-week double-blind trial comparing 1% drops of domperidone, 1% metoclopramide drops or placebo." | 9.04 | Domperidone drops in the symptomatic treatment of chronic paediatric vomiting and regurgitation. A comparison with metoclopramide. ( Ameryckx, L; De Loore, I; Van Ravensteyn, H, 1979) |
| "The authors studied the effect of single intakes of metoclopramide on the acid and pepsin secretion in patients with chronic gastritis and duodenal ulcer." | 7.67 | [The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer]. ( Makara, VZ; Skliarov, EIa, 1989) |
| "Metoclopramide has in previous studies been found to be synergic with acupuncture analgesia both in the laboratory and in the clinics." | 5.27 | No synergism between metoclopramide and acupuncture in chronic pain. ( Junnila, SY, 1986) |
| "The short elimination half-life of metoclopramide necessitates frequent administration for optimal relief of nausea." | 5.07 | Comparison of the efficacy, safety, and pharmacokinetics of controlled release and immediate release metoclopramide for the management of chronic nausea in patients with advanced cancer. ( Babul, N; Bruera, ED; Darke, AC; Harsanyi, Z; LeGatt, DF; MacDonald, RN; MacEachern, TJ; Spachynski, KA, 1994) |
| "A double-blind, placebo-controlled trial was performed to determine the therapeutic efficacy of cisapride in patients with refractory functional dyspepsia." | 5.07 | Efficacy of cisapride in functional dyspepsia resistant to domperidone or metoclopramide: a double-blind, placebo-controlled study. ( De Nutte, N; Gooris, JP; Van Eeghem, P; Van Outryve, M, 1993) |
| "A double-blind comparison of metoclopramide versus placebo was performed on 8 cirrhotic patients with nausea (8 cases) and heartburn (3 of the 8 cases) plus mild portal-systemic encephalopathy." | 5.05 | Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial. ( Ballesteros, A; Briones, A; Garcia Ramos, G; Garza, J; Rosales, J; Strauss, R; Uribe, M; Villalobos, A, 1985) |
| "Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn." | 5.04 | A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977) |
| "Forty-seven infants and children suffering from chronic vomiting or regurgitation, participated in a two-week double-blind trial comparing 1% drops of domperidone, 1% metoclopramide drops or placebo." | 5.04 | Domperidone drops in the symptomatic treatment of chronic paediatric vomiting and regurgitation. A comparison with metoclopramide. ( Ameryckx, L; De Loore, I; Van Ravensteyn, H, 1979) |
| "In patients with advanced cancer not being treated with chemotherapy or radiation therapy, metoclopramide can be used to reduce nausea and vomiting." | 4.88 | [Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review]. ( Alt-Epping, B; Benze, G; Geyer, A; Nauck, F, 2012) |
| "The authors studied the effect of single intakes of metoclopramide on the acid and pepsin secretion in patients with chronic gastritis and duodenal ulcer." | 3.67 | [The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer]. ( Makara, VZ; Skliarov, EIa, 1989) |
| "Metoclopramide (Paspertin) was administered to 30 patients with duodenal ulcer at an average dosage of 2 tablets three times daily (= 60 mg/day)." | 3.65 | [Advances in the treatment of duodenal ulcer. Shortened healing time under high Paspertin dosage (author's transl)]. ( Schütz, E, 1976) |
| "Metoclopramide was started at 5 mg daily and titrated as needed to a maximum dose of 40 mg daily." | 2.71 | A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorder. ( Castellanos, FX; Craven-Thuss, B; McKinlay, BD; Nicolson, R; Smith, J, 2005) |
| "Dyspepsia affects one in four Australians; of those who present in general practice, the majority will have functional or non-ulcer dyspepsia, with no structural explanation for their symptoms." | 2.39 | Modern management of dyspepsia. ( Talley, NJ, 1996) |
| "The esophageal pH probe identifies gastroesophageal reflux." | 2.38 | Chronic pulmonary aspiration in children. ( Bauer, ML; Figueroa-Colon, R; Georgeson, K; Young, DW, 1993) |
| "The cough was eliminated or markedly improved in 38 patients (86%) after 4 weeks and by 8 weeks in the remaining 6 patients." | 1.32 | Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment. ( Kallay, MC; Poe, RH, 2003) |
| "Metoclopramide has in previous studies been found to be synergic with acupuncture analgesia both in the laboratory and in the clinics." | 1.27 | No synergism between metoclopramide and acupuncture in chronic pain. ( Junnila, SY, 1986) |
| "Magnesium deficiency was present in seven patients and its correction resulted in amelioration of the symptom complex." | 1.26 | Chronic intestinal pseudo-obstruction. ( Brandenburg, D; Brooks, WS; Hersh, T; Hirsh, EH, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (50.00) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 6 (15.00) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lacy, BE | 1 |
| Cangemi, DJ | 1 |
| Benze, G | 1 |
| Alt-Epping, B | 1 |
| Geyer, A | 1 |
| Nauck, F | 1 |
| Lyday, WD | 1 |
| DiBaise, JK | 1 |
| Poe, RH | 1 |
| Kallay, MC | 1 |
| Bruera, E | 2 |
| Moyano, JR | 1 |
| Sala, R | 1 |
| Rico, MA | 1 |
| Bosnjak, S | 1 |
| Bertolino, M | 1 |
| Willey, J | 1 |
| Strasser, F | 1 |
| Palmer, JL | 1 |
| Nicolson, R | 1 |
| Craven-Thuss, B | 1 |
| Smith, J | 1 |
| McKinlay, BD | 1 |
| Castellanos, FX | 1 |
| Parra, A | 1 |
| Ramírez-Peredo, J | 1 |
| Hidalgo, R | 1 |
| Morales-Toquero, A | 1 |
| Velásquez-Ramírez, G | 1 |
| Ruiz-Argüelles, A | 1 |
| Ruiz-Argüelles, GJ | 1 |
| Judd, SJ | 1 |
| Burkov, SG | 1 |
| Hirsh, EH | 1 |
| Brandenburg, D | 1 |
| Hersh, T | 1 |
| Brooks, WS | 1 |
| Sciarretta, G | 1 |
| Turba, E | 1 |
| Verri, A | 1 |
| Pinetti, P | 1 |
| Malaguti, P | 1 |
| Bruera, ED | 1 |
| MacEachern, TJ | 1 |
| Spachynski, KA | 1 |
| LeGatt, DF | 1 |
| MacDonald, RN | 1 |
| Babul, N | 2 |
| Harsanyi, Z | 2 |
| Darke, AC | 1 |
| Bauer, ML | 1 |
| Figueroa-Colon, R | 1 |
| Georgeson, K | 1 |
| Young, DW | 1 |
| Ducla-Soares, JL | 1 |
| Guerreiro, AS | 1 |
| Póvoa, P | 1 |
| Alvares, E | 1 |
| Guerreiro, L | 1 |
| Carrilho, F | 1 |
| Santos, M | 1 |
| Figueirinhas, J | 1 |
| Carvalho, M | 1 |
| Van Outryve, M | 1 |
| De Nutte, N | 1 |
| Van Eeghem, P | 1 |
| Gooris, JP | 1 |
| Talley, NJ | 1 |
| Twycross, R | 1 |
| Rochon, PA | 1 |
| Gurwitz, JH | 1 |
| Belzile, M | 1 |
| Neumann, C | 1 |
| Darke, A | 1 |
| Geller, LI | 1 |
| Petrenko, VF | 1 |
| Dotevall, G | 1 |
| McCallum, RW | 1 |
| Ippoliti, AF | 1 |
| Cooney, C | 1 |
| Sturdevant, RA | 1 |
| De Loore, I | 1 |
| Van Ravensteyn, H | 1 |
| Ameryckx, L | 1 |
| Wilson, JD | 1 |
| King, DJ | 1 |
| Sheridan, B | 1 |
| Tkaczewski, W | 1 |
| Chojnacki, J | 1 |
| Dziekański, S | 1 |
| Szeszko, A | 1 |
| Schütz, E | 1 |
| Putnam, PE | 1 |
| Orenstein, SR | 1 |
| Wessel, HB | 1 |
| Stowe, RM | 1 |
| Polous, IuM | 1 |
| Kurko, VS | 1 |
| Salim, AS | 1 |
| Sachdev, P | 1 |
| Chee, KY | 1 |
| Reshetilov, IuI | 1 |
| Skliarov, EIa | 1 |
| Makara, VZ | 1 |
| Castell, DO | 2 |
| Junnila, SY | 1 |
| Lieberman, DA | 1 |
| Malfertheiner, P | 2 |
| Büchler, M | 2 |
| Müller, A | 2 |
| Ditschuneit, H | 2 |
| Frolkis, AW | 1 |
| Uribe, M | 1 |
| Ballesteros, A | 1 |
| Strauss, R | 1 |
| Rosales, J | 1 |
| Garza, J | 1 |
| Villalobos, A | 1 |
| Briones, A | 1 |
| Garcia Ramos, G | 1 |
6 reviews available for metoclopramide and Chronic Illness
| Article | Year |
|---|---|
[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review].
Topics: Antiemetics; Antipsychotic Agents; Chronic Disease; Domperidone; Dopamine Antagonists; Drug Therapy, | 2012 |
Primary hyperprolactinaemia and chronic anovulation: pathophysiology and management.
Topics: Anovulation; Breast Feeding; Chronic Disease; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate | 1982 |
Chronic pulmonary aspiration in children.
Topics: Bethanechol; Bethanechol Compounds; Bronchoscopy; Child; Chronic Disease; Diet Therapy; Gastric Acid | 1993 |
[Pure autonomic failure].
Topics: Autonomic Nervous System Diseases; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combinati | 1993 |
Modern management of dyspepsia.
Topics: Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bismuth; Child; C | 1996 |
Optimising drug treatment for elderly people: the prescribing cascade.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Benzothiadiazines; Chronic D | 1997 |
12 trials available for metoclopramide and Chronic Illness
| Article | Year |
|---|---|
Dexamethasone in addition to metoclopramide for chronic nausea in patients with advanced cancer: a randomized controlled trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Chronic Disease; Dexamethasone; D | 2004 |
A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorder.
Topics: Adolescent; Child; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Dopamine | 2005 |
Comparison of the efficacy, safety, and pharmacokinetics of controlled release and immediate release metoclopramide for the management of chronic nausea in patients with advanced cancer.
Topics: Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Humans; Metoclopramide; Nausea; N | 1994 |
Efficacy of cisapride in functional dyspepsia resistant to domperidone or metoclopramide: a double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Chronic Disease; Cisapride; Domperidone; Double-Blind Method; Dyspepsia; Fe | 1993 |
A double-blind, crossover study of controlled-release metoclopramide and placebo for the chronic nausea and dyspepsia of advanced cancer.
Topics: Aged; Antiemetics; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; M | 2000 |
[Evaluation of the action of drug agents on the tonus of the lower esophageal sphincter].
Topics: Atropine; Bicarbonates; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Duodenal Disease | 1978 |
A controlled trial of metoclopramide in symptomatic gastroesophageal reflux.
Topics: Antacids; Anxiety; Chronic Disease; Clinical Trials as Topic; Esophagus; Female; Gastroesophageal Re | 1977 |
Domperidone drops in the symptomatic treatment of chronic paediatric vomiting and regurgitation. A comparison with metoclopramide.
Topics: Antiemetics; Benzimidazoles; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Dou | 1979 |
Role of oxygen-derived free radical scavengers in the treatment of recurrent pain produced by chronic pancreatitis. A new approach.
Topics: Abdominal Pain; Adult; Aged; Alcoholism; Allopurinol; Chronic Disease; Dimethyl Sulfoxide; Double-Bl | 1991 |
Pharmacological characterization of tardive akathisia.
Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztr | 1990 |
Medical therapy for chronic reflux esophagitis. Long-term follow-up.
Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; | 1987 |
Successful administration of metoclopramide for the treatment of nausea in patients with advanced liver disease. A double-blind controlled trial.
Topics: Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Gastroesophageal Reflux; Hep | 1985 |
22 other studies available for metoclopramide and Chronic Illness
| Article | Year |
|---|---|
Controversies in Gastroparesis: Discussing the Sticky Points.
Topics: Abdominal Pain; Antiemetics; Chronic Disease; Diabetes Complications; Diagnosis, Differential; Diagn | 2021 |
Metoclopramide-stimulated gastric emptying scintigraphy: does it predict symptom response to prokinetic therapy in chronic gastroparesis?
Topics: Chronic Disease; Dopamine Antagonists; Dose-Response Relationship, Drug; Gastric Emptying; Gastroint | 2002 |
Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Chronic Disease; Cisapride; | 2003 |
Altered functional status of the hypothalamic dopaminergic tone in patients with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a pilot study.
Topics: Adult; Age Factors; Anemia, Aplastic; Area Under Curve; Body Mass Index; Chronic Disease; Dopamine; | 2006 |
[Metoclopramide in the complex treatment of chronic cholecystitis in pregnant women].
Topics: Adolescent; Adult; Cholecystitis; Chronic Disease; Female; Humans; Metoclopramide; Pregnancy; Pregna | 1984 |
Chronic intestinal pseudo-obstruction.
Topics: Adult; Aged; Celiac Disease; Chronic Disease; Female; Humans; Intestinal Obstruction; Intestinal Pse | 1981 |
[Gastric emptying in dyspeptic syndromes during treatment with a combination of carbenoxolone and metoclopramide, studied with a meal labeled with 99mTc colloidal sulfate].
Topics: Adult; Aged; Carbenoxolone; Chronic Disease; Drug Therapy, Combination; Dyspepsia; Female; Gastric E | 1980 |
Re: Metoclopramide for chronic nausea.
Topics: Antiemetics; Chronic Disease; Humans; Metoclopramide; Nausea | 1997 |
[Drug therapy of chronic gastritis].
Topics: Achlorhydria; Carbenoxolone; Chronic Disease; Gastritis; Glutamates; Histamine H2 Antagonists; Human | 1978 |
Plasma prolactin levels before and during propranolol treatment in chronic schizophrenia.
Topics: Chronic Disease; Humans; Male; Metoclopramide; Prolactin; Propranolol; Psychiatric Status Rating Sca | 1979 |
[Combined administration of metoclopramide, scopolan and proacid in the treatment of chronic duodenal ulcer].
Topics: Adult; Aluminum; Aluminum Hydroxide; Butylscopolammonium Bromide; Chronic Disease; Drug Therapy, Com | 1978 |
[Advances in the treatment of duodenal ulcer. Shortened healing time under high Paspertin dosage (author's transl)].
Topics: Adolescent; Adult; Aged; Chronic Disease; Duodenal Ulcer; Female; Gastric Juice; Gastrointestinal Mo | 1976 |
Tardive dyskinesia associated with use of metoclopramide in a child.
Topics: Child, Preschool; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Dyskinesia, | 1992 |
[The use of sound waves, drug preparations and electrostimulation in the combined treatment of patients with chronic functional duodenal obstruction].
Topics: Adult; Aged; Chronic Disease; Combined Modality Therapy; Duodenal Obstruction; Electric Stimulation | 1991 |
[The cerucal treatment of patients with hypomotoric gastroduodenal dyskinesias and dystonias].
Topics: Chronic Disease; Drug Evaluation; Duodenal Diseases; Duodenum; Gastrointestinal Motility; Humans; Me | 1990 |
[The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer].
Topics: Adult; Chronic Disease; Drug Evaluation; Female; Gastric Acid; Gastric Juice; Gastritis; Histamine; | 1989 |
Future medical therapy of reflux esophagitis.
Topics: Animals; Chronic Disease; Drug Therapy, Combination; Esophagitis, Peptic; Gastric Acid; Gastrointest | 1986 |
No synergism between metoclopramide and acupuncture in chronic pain.
Topics: Acupuncture Therapy; Adult; Chronic Disease; Combined Modality Therapy; Double-Blind Method; Female; | 1986 |
Long-term therapy for chronic gastroesophageal reflux.
Topics: Chronic Disease; Cimetidine; Drug Therapy, Combination; Esophagogastric Junction; Gastroesophageal R | 1987 |
Fluorescein dilaurate serum test: a rapid tubeless pancreatic function test.
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Fluorescein; Fluoresceins; Humans; Male; Metoclopr | 1987 |
[The fluorescein dilaurate serum test following metoclopramide and secretin stimulation for evaluating pancreatic function. Contribution to the diagnosis of chronic pancreatitis].
Topics: Chronic Disease; Diagnosis, Differential; Female; Fluoresceins; Humans; Male; Metoclopramide; Middle | 1987 |
[New results in the diagnosis and therapy of functional disorders of the large intestine].
Topics: Alkaline Phosphatase; Chronic Disease; Colitis, Ulcerative; Colonic Diseases, Functional; Diphenoxyl | 1986 |