metoclopramide has been researched along with Cephalgia, Vascular in 5 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "34) and no adverse reactions in the study period." | 2.73 | Intravenous administration of metoclopramide by 2 min bolus vs 15 min infusion: does it affect the improvement of headache while reducing the side effects? ( Ayrik, C; Erdur, B; Ergin, A; Ergin, N; Parlak, I; Parlak, M; Tomruk, O; Turkcuer, I, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cicek, M | 1 |
| Karcioglu, O | 1 |
| Parlak, I | 2 |
| Ozturk, V | 1 |
| Duman, O | 1 |
| Serinken, M | 1 |
| Guryay, M | 1 |
| Erdur, B | 1 |
| Parlak, M | 1 |
| Ergin, A | 1 |
| Turkcuer, I | 1 |
| Tomruk, O | 1 |
| Ayrik, C | 1 |
| Ergin, N | 1 |
| Damasio, H | 1 |
| Belgrade, MJ | 1 |
| Ling, LJ | 1 |
| Schleevogt, MB | 1 |
| Ettinger, MG | 1 |
| Ruiz, E | 1 |
| Klimek, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031] | Phase 4 | 54 participants (Actual) | Interventional | 2016-03-17 | Completed | ||
| Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130] | Phase 4 | 58 participants (Actual) | Interventional | 2017-05-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 33.7 |
| Study Arm | 21.2 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 63.5 |
| Study Arm | 43.5 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 38.9 |
| Study Arm | 22.9 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 2 |
| Study Arm | 3 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 3 |
| Study Arm | 3 |
3 trials available for metoclopramide and Cephalgia, Vascular
| Article | Year |
|---|---|
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum | 2004 |
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum | 2004 |
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum | 2004 |
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum | 2004 |
Intravenous administration of metoclopramide by 2 min bolus vs 15 min infusion: does it affect the improvement of headache while reducing the side effects?
Topics: Adult; Akathisia, Drug-Induced; Dopamine Antagonists; Double-Blind Method; Drug Administration Sched | 2007 |
Comparison of single-dose meperidine, butorphanol, and dihydroergotamine in the treatment of vascular headache.
Topics: Adult; Butorphanol; Clinical Trials as Topic; Dihydroergotamine; Drug Therapy, Combination; Female; | 1989 |
2 other studies available for metoclopramide and Cephalgia, Vascular
| Article | Year |
|---|---|
Drug management of adult vascular headaches (migraine and cluster headache): Part I--Treatment of the acute attack.
Topics: Cluster Headache; Dihydroergotamine; Ergotamine; Humans; Metoclopramide; Migraine Disorders; Vascula | 1984 |
Growth hormone and prolactin levels in the course of metoclopramide test in headache patients.
Topics: Adolescent; Adult; Female; Growth Hormone; Humans; Male; Metoclopramide; Middle Aged; Prolactin; Vas | 1985 |