metoclopramide has been researched along with Cardiotoxicity in 1 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data demonstrate that the clinically relevant cardiotoxicity of domperidone and metoclopramide corresponds to a rather potent and local anesthetic-like inhibition of cardiac Na channels including Nav1." | 3.85 | Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels. ( Doll, T; Heineke, J; Leffler, A; Stoetzer, C; Voelker, M; Wegner, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoetzer, C | 1 |
| Voelker, M | 1 |
| Doll, T | 1 |
| Heineke, J | 1 |
| Wegner, F | 1 |
| Leffler, A | 1 |
1 other study available for metoclopramide and Cardiotoxicity
| Article | Year |
|---|---|
Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels.
Topics: Animals; Animals, Newborn; Antiemetics; Binding Sites; Cardiotoxicity; Domperidone; Dose-Response Re | 2017 |