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metoclopramide and Cardiac Arrest, Sudden

metoclopramide has been researched along with Cardiac Arrest, Sudden in 5 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"The results of two large epidemiological studies on the association between domperidone and ventricular arrhythmia or sudden cardiac death were published in 2015; one study was conducted in Taiwan and the other in the United Kingdom."7.83Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia. ( , 2016)
"We aimed to examine the association between cisapride and ventricular arrhythmia, and examine the relationship to dose and CYP3A4 inhibitors."7.74Cisapride and ventricular arrhythmia. ( Bilker, WB; Hennessy, S; Kimmel, SE; Leonard, CE; Newcomb, C, 2008)
" From these publications, it cannot be concluded that domperidone exposure definitely increases the risk of "sudden cardiac death", "death associated with ventricular arrhythmia" or "ventricular arrhythmia" The most concrete result of these studies is that the risk is higher with metoclopramide exposure compared to domperidone exposure."5.01Critical review of European Medicines Agency (EMA) assessment report and related literature on domperidone. ( Tuğlular, I; Yüksel, K, 2019)
"The results of two large epidemiological studies on the association between domperidone and ventricular arrhythmia or sudden cardiac death were published in 2015; one study was conducted in Taiwan and the other in the United Kingdom."3.83Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia. ( , 2016)
"We aimed to examine the association between cisapride and ventricular arrhythmia, and examine the relationship to dose and CYP3A4 inhibitors."3.74Cisapride and ventricular arrhythmia. ( Bilker, WB; Hennessy, S; Kimmel, SE; Leonard, CE; Newcomb, C, 2008)
"Out-of-hospital sudden cardiac death was assessed by linkage with Hospital Episode Statistics and death certificates."1.42Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study. ( Arana, A; Fife, D; Johannes, CB; McQuay, LJ; Rothman, KJ; Varas-Lorenzo, C, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yüksel, K1
Tuğlular, I1
Arana, A1
Johannes, CB1
McQuay, LJ1
Varas-Lorenzo, C1
Fife, D1
Rothman, KJ1
Hennessy, S2
Leonard, CE2
Palumbo, CM1
Bilker, WB2
Newcomb, C2
Kimmel, SE2

Reviews

1 review available for metoclopramide and Cardiac Arrest, Sudden

ArticleYear
Critical review of European Medicines Agency (EMA) assessment report and related literature on domperidone.
    International journal of clinical pharmacy, 2019, Volume: 41, Issue:2

    Topics: Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Humans; Metoclopramide; Risk

2019

Other Studies

4 other studies available for metoclopramide and Cardiac Arrest, Sudden

ArticleYear
Metoclopramide, domperidone: sudden cardiac death, ventricular arrhythmia.
    Prescrire international, 2016, Volume: 25, Issue:175

    Topics: Antiemetics; Arrhythmias, Cardiac; Clinical Decision-Making; Death, Sudden, Cardiac; Domperidone; Do

2016
Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study.
    Drug safety, 2015, Volume: 38, Issue:12

    Topics: Aging; Antiemetics; Case-Control Studies; Death, Sudden, Cardiac; Domperidone; Dose-Response Relatio

2015
Diagnostic codes for sudden cardiac death and ventricular arrhythmia functioned poorly to identify outpatient events in EPIC's General Practice Research Database.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:12

    Topics: Arrhythmias, Cardiac; Cisapride; Cohort Studies; Databases, Factual; Death, Sudden, Cardiac; Domperi

2008
Cisapride and ventricular arrhythmia.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:3

    Topics: Adult; Aged; Arrhythmias, Cardiac; Case-Control Studies; Cisapride; Cytochrome P-450 CYP3A; Death, S

2008