metoclopramide has been researched along with Cancer of Ovary in 30 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the combined effect of granisetron and methylprednisolone against acute emesis induced by cytotoxic agents, we investigated the clinical response and the urinary excretion of 5-HIAA in 85 patients with ovarian cancer who received the same anticancer chemotherapeutic regimen in a prospective randomized trial." | 9.08 | Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents. ( Cheng, X; Itamochi, H; Kigawa, J; Minagawa, Y; Okada, M; Terakawa, N, 1997) |
| "To determine the severity of emesis caused by ultra-high-dose cisplatin-carboplatin chemotherapy and to compare the antiemetic efficacy of an ondansetron regimen and a metoclopramide regimen." | 9.07 | Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy. ( Fanning, J; Hilgers, RD, 1994) |
| " The syndrome was associated with metoclopramide antiemetic therapy given for post-operative nausea and vomiting." | 7.68 | Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy. ( Bakri, YN; Kawi, Z; Khan, R; Subhi, J, 1992) |
| "In prospective alternative crossover test, we confirmed significant superiority of a three-drug combination of clonazepam (C) lorazepam (L) and dexamethasone (D) to (L) and (D) to control vomiting induced by 50 mg/m CDDP containing chemotherapy for gynecological malignancies (p less than 0." | 7.68 | [Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting]. ( Asano, H; Hatae, M; Hokanishi, H; Mitsuo, M; Nakamura, Y; Onishi, Y; Sakurai, K, 1990) |
| "Vomiting was not satisfactorily prevented by either treatment." | 6.67 | Betamethasone-dixyrazine versus betamethasone-metoclopramide as antiemetic treatment of cisplatin-doxorubicin-induced nausea in ovarian carcinoma patients. ( Hallén, C; Sorbe, B, 1991) |
| " It is concluded that there is a dose-response relationship for the antiemetic effect of metoclopramide." | 6.66 | High-dose versus low-dose metoclopramide in the prevention of cisplatin-induced emesis. A randomized crossover study in patients with ovarian carcinoma. ( Grande, T; Moxnes, A; Onsrud, M; Solesvik, O; Sollien, A, 1988) |
| "Metoclopramide was given at a dosage of 2 mg/kg (H) or 1 mg/kg (M), intravenously, 30 minutes before and 2." | 6.66 | [Randomized controlled study of high-dose metoclopramide (2 mg/kg x 4:H) vs moderate-dose metoclopramide (1 mg/kg x 4:M) in the prevention of CDDP-induced emesis]. ( Dozono, H; Ohmi, K, 1986) |
| "Metoclopramide (MCP) was given i." | 6.65 | Randomized open cross-over trial between metoclopramide (MCP) and dexamethazone (DXM) for the prevention of cisplatin-induced nausea and vomiting. ( Carlini, P; Cognetti, F; Conti, EM; Cortese, M; Pinnarò, P; Pollera, CF, 1984) |
| "and metoclopramide 0." | 5.29 | Treatment of cisplatin-related nausea and vomiting with a combination of ondansetron and metoclopramide: a pilot study. ( Cannata, G; Gebbia, N; Gebbia, V; Testa, A, 1996) |
| "To evaluate the combined effect of granisetron and methylprednisolone against acute emesis induced by cytotoxic agents, we investigated the clinical response and the urinary excretion of 5-HIAA in 85 patients with ovarian cancer who received the same anticancer chemotherapeutic regimen in a prospective randomized trial." | 5.08 | Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents. ( Cheng, X; Itamochi, H; Kigawa, J; Minagawa, Y; Okada, M; Terakawa, N, 1997) |
| "To improve the treatment of cisplatin-induced acute emesis and vomiting, the adjuvant effect of two different doses of metoclopramide and metoclopramide plus droperidol was compared to a defined standard antiemetic regiment." | 5.07 | Comparison of four antiemetic regimens for the treatment of cisplatin-induced vomiting. ( Hernádi, Z; Juhász, B; Lampé, L; Póka, R, 1993) |
| "To determine the severity of emesis caused by ultra-high-dose cisplatin-carboplatin chemotherapy and to compare the antiemetic efficacy of an ondansetron regimen and a metoclopramide regimen." | 5.07 | Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy. ( Fanning, J; Hilgers, RD, 1994) |
| " The syndrome was associated with metoclopramide antiemetic therapy given for post-operative nausea and vomiting." | 3.68 | Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy. ( Bakri, YN; Kawi, Z; Khan, R; Subhi, J, 1992) |
| "In prospective alternative crossover test, we confirmed significant superiority of a three-drug combination of clonazepam (C) lorazepam (L) and dexamethasone (D) to (L) and (D) to control vomiting induced by 50 mg/m CDDP containing chemotherapy for gynecological malignancies (p less than 0." | 3.68 | [Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting]. ( Asano, H; Hatae, M; Hokanishi, H; Mitsuo, M; Nakamura, Y; Onishi, Y; Sakurai, K, 1990) |
| "Female patients with ovarian cancer are at high risk for emesis." | 2.67 | Ondansetron plus dexamethasone versus metoclopramide plus dexamethasone plus diphenhydramine in cisplatin-treated patients with ovarian cancer. Italian Group for Antiemetic Research. ( , 1994) |
| "Vomiting was not satisfactorily prevented by either treatment." | 2.67 | Betamethasone-dixyrazine versus betamethasone-metoclopramide as antiemetic treatment of cisplatin-doxorubicin-induced nausea in ovarian carcinoma patients. ( Hallén, C; Sorbe, B, 1991) |
| " It is concluded that there is a dose-response relationship for the antiemetic effect of metoclopramide." | 2.66 | High-dose versus low-dose metoclopramide in the prevention of cisplatin-induced emesis. A randomized crossover study in patients with ovarian carcinoma. ( Grande, T; Moxnes, A; Onsrud, M; Solesvik, O; Sollien, A, 1988) |
| "Metoclopramide was given at a dosage of 2 mg/kg (H) or 1 mg/kg (M), intravenously, 30 minutes before and 2." | 2.66 | [Randomized controlled study of high-dose metoclopramide (2 mg/kg x 4:H) vs moderate-dose metoclopramide (1 mg/kg x 4:M) in the prevention of CDDP-induced emesis]. ( Dozono, H; Ohmi, K, 1986) |
| "Metoclopramide (MCP) was given i." | 2.65 | Randomized open cross-over trial between metoclopramide (MCP) and dexamethazone (DXM) for the prevention of cisplatin-induced nausea and vomiting. ( Carlini, P; Cognetti, F; Conti, EM; Cortese, M; Pinnarò, P; Pollera, CF, 1984) |
| "and metoclopramide 0." | 1.29 | Treatment of cisplatin-related nausea and vomiting with a combination of ondansetron and metoclopramide: a pilot study. ( Cannata, G; Gebbia, N; Gebbia, V; Testa, A, 1996) |
| "Intestinal obstruction is a relatively common clinical problem in patients with advanced cancer, particularly those with colorectal and ovarian tumours." | 1.28 | Non-operative management of malignant intestinal obstruction. ( Elder, P; Isbister, WH; Symons, L, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (40.00) | 18.7374 |
| 1990's | 17 (56.67) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cognetti, F | 1 |
| Pinnarò, P | 1 |
| Carlini, P | 1 |
| Conti, EM | 1 |
| Cortese, M | 1 |
| Pollera, CF | 1 |
| Bolis, PF | 1 |
| Guaschino, S | 1 |
| Paganelli, AM | 1 |
| Sampaolo, P | 1 |
| Misra, R | 1 |
| Agarwal, N | 1 |
| Póka, R | 1 |
| Hernádi, Z | 1 |
| Juhász, B | 1 |
| Lampé, L | 1 |
| Fanning, J | 1 |
| Hilgers, RD | 1 |
| Goddard, M | 1 |
| Hansen, O | 1 |
| Pfeiffer, P | 1 |
| Madsen, B | 1 |
| Andersen, I | 1 |
| Hansen, B | 1 |
| Mathiesen, B | 1 |
| Gebbia, V | 1 |
| Testa, A | 1 |
| Cannata, G | 1 |
| Gebbia, N | 1 |
| Kigawa, J | 1 |
| Minagawa, Y | 1 |
| Itamochi, H | 1 |
| Cheng, X | 1 |
| Okada, M | 1 |
| Terakawa, N | 1 |
| Sawaguchi, K | 1 |
| Yabushita, H | 1 |
| Tsukada, H | 1 |
| Yamada, H | 1 |
| Noguchi, M | 1 |
| Nakanishi, M | 1 |
| Morrow, GR | 1 |
| Hickok, JT | 1 |
| DuBeshter, B | 1 |
| Lipshultz, SE | 1 |
| Manusirivithaya, S | 1 |
| Chareoniam, V | 1 |
| Isariyodom, P | 1 |
| Sungsab, D | 1 |
| Fürst, CJ | 2 |
| Johansson, S | 2 |
| Fredrikson, M | 2 |
| Hursti, T | 2 |
| Steineck, G | 2 |
| Peterson, C | 2 |
| Bakri, YN | 1 |
| Khan, R | 1 |
| Subhi, J | 1 |
| Kawi, Z | 1 |
| Ochiai, K | 1 |
| Isonishi, S | 1 |
| Kimura, E | 1 |
| Yokoyama, S | 1 |
| Sasaki, H | 1 |
| Arihiro, T | 1 |
| Terashima, Y | 1 |
| Sorbe, B | 2 |
| Hallén, C | 2 |
| Isbister, WH | 1 |
| Elder, P | 1 |
| Symons, L | 1 |
| Hatae, M | 1 |
| Nakamura, Y | 1 |
| Mitsuo, M | 1 |
| Sakurai, K | 1 |
| Asano, H | 1 |
| Onishi, Y | 1 |
| Hokanishi, H | 1 |
| Chen, JT | 1 |
| Hirai, Y | 1 |
| Yagi, H | 1 |
| Katase, K | 1 |
| Shimizu, Y | 1 |
| Nakayama, K | 1 |
| Teshima, H | 1 |
| Hamada, T | 1 |
| Fujimoto, I | 1 |
| Yamuchi, K | 1 |
| Kobayashi, H | 1 |
| Onsrud, M | 1 |
| Moxnes, A | 1 |
| Sollien, A | 1 |
| Grande, T | 1 |
| Solesvik, O | 1 |
| Rosenblatt, E | 1 |
| Lev, LM | 1 |
| Robinson, E | 1 |
| Martin-Jimenez, M | 1 |
| Diaz-Rubio, E | 1 |
| Gonzalez Larriba, JL | 1 |
| Sangro, B | 1 |
| Breitbart, W | 1 |
| Dozono, H | 1 |
| Ohmi, K | 1 |
| Markman, M | 1 |
| Newman, DR | 1 |
| Hawkins, RS | 1 |
| Gez, E | 1 |
| Catane, R | 1 |
| Pfau, L | 1 |
| Biran, S | 1 |
18 trials available for metoclopramide and Cancer of Ovary
| Article | Year |
|---|---|
Randomized open cross-over trial between metoclopramide (MCP) and dexamethazone (DXM) for the prevention of cisplatin-induced nausea and vomiting.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cl | 1984 |
Ondansetron plus dexamethasone versus metoclopramide plus dexamethasone plus diphenhydramine in cisplatin-treated patients with ovarian cancer. Italian Group for Antiemetic Research.
Topics: Adult; Aged; Aged, 80 and over; Cisplatin; Dexamethasone; Diphenhydramine; Drug Combinations; Drug T | 1994 |
Comparison of four antiemetic regimens for the treatment of cisplatin-induced vomiting.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Droperidol; Female; Humans; | 1993 |
Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Dexamethasone; Diphenh | 1994 |
Sustained-release metoclopramide plus methylprednisolone versus placebo plus methylprednisolone as antiemetic prophylaxis during non-cisplatin chemotherapy. A randomized double-blind cross-over trial.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplas | 1996 |
Combination effect of granisetron and methylprednisolone for preventing emesis induced by cytotoxic agents.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Granisetron; Humans; Hydroxyi | 1997 |
[Clinical studies of oral antiemetic drugs on delayed emesis induced by cancer chemotherapy].
Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Carboplatin; Cisplatin; Cross-Over Studies | 1999 |
Changes in clinical measures of autonomic nervous system function related to cancer chemotherapy-induced nausea.
Topics: Aged; Antiemetics; Antineoplastic Agents; Autonomic Nervous System; Blood Pressure; Carboplatin; Cis | 1999 |
Comparison of ondansetron-dexamethasone-lorazepam versus metoclopramide-dexamethasone-lorazepam in the control of cisplatin induced emesis.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Chi-Square Distribution; Cisplatin; Dexamethasone; | 2001 |
Effects of ondansetron on chemotherapy-induced acute and delayed emesis--a pilot study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Biperiden; Cisplatin; Dexa | 1991 |
Betamethasone-dixyrazine versus betamethasone-metoclopramide as antiemetic treatment of cisplatin-doxorubicin-induced nausea in ovarian carcinoma patients.
Topics: Activities of Daily Living; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Betamethaso | 1991 |
Antiemetic treatment of chemotherapy-induced nausea in ovarian carcinoma patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents; Betamethasone; Cisplatin; Clin | 1989 |
[Effect of medical vagotomy on the CDDP induced nausea and vomiting evaluated by the chemotherapy-vomiting time (CV time)].
Topics: Acetaminophen; Adult; Cisplatin; Female; Humans; Metoclopramide; Middle Aged; Nausea; Ovarian Neopla | 1988 |
[The effect of metoclopramide, dexamethasone and antihistamine in the prevention of PAC chemotherapy-induced emesis].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dexamethasone; D | 1988 |
High-dose versus low-dose metoclopramide in the prevention of cisplatin-induced emesis. A randomized crossover study in patients with ovarian carcinoma.
Topics: Adult; Aged; Cisplatin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Metoc | 1988 |
High-dose dexamethasone and high-dose metoclopramide versus high-dose dexamethasone and sulpiride in the management of cisplatin-induced emesis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dexamethasone; | 1988 |
Antiemetic combination for PAC (cisplatin-adriamycin-cyclophosphamide) chemotherapy-induced emesis in ovarian cancer.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials | 1987 |
[Randomized controlled study of high-dose metoclopramide (2 mg/kg x 4:H) vs moderate-dose metoclopramide (1 mg/kg x 4:M) in the prevention of CDDP-induced emesis].
Topics: Aged; Cisplatin; Drug Administration Schedule; Female; Humans; Metoclopramide; Middle Aged; Nausea; | 1986 |
12 other studies available for metoclopramide and Cancer of Ovary
| Article | Year |
|---|---|
A comparison of droperidol and metoclopramide in the treatment of nausea and vomiting during cis-platinum polichemotherapy in ovarian carcinoma.
Topics: Antineoplastic Agents; Cisplatin; Droperidol; Drug Therapy, Combination; Female; Humans; Metoclopram | 1981 |
Effective control of cisplatin induced emesis by combination drug regimen.
Topics: Adult; Cisplatin; Dexamethasone; Drug Administration Schedule; Drug Combinations; Female; Follow-Up | 1994 |
The real costs of emesis.
Topics: Antiemetics; Carboplatin; Cisplatin; Drug Costs; Female; Humans; Metoclopramide; Ondansetron; Ovaria | 1993 |
Treatment of cisplatin-related nausea and vomiting with a combination of ondansetron and metoclopramide: a pilot study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Epirubicin; Female; Hu | 1996 |
Control of cisplatin induced emesis--a multidisciplinary intervention strategy.
Topics: Adult; Aged; Biperiden; Cisplatin; Female; Humans; Lorazepam; Metoclopramide; Middle Aged; Nausea; O | 1992 |
Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy.
Topics: Adenocarcinoma; Antiemetics; Female; Humans; Metoclopramide; Middle Aged; Nausea; Neuroleptic Malign | 1992 |
[Cyclic high dose CAP therapy by short-stay admission for ovarian malignancies--to increase total dose of CDDP and to improve quality of life of patients].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Dru | 1991 |
Non-operative management of malignant intestinal obstruction.
Topics: Adult; Aged; Colorectal Neoplasms; Drug Combinations; Female; Humans; Infusions, Intravenous; Intest | 1990 |
[Evaluation of antiemetic effect of clonazepam, metoclopramide, dexamethasone and diphenhydramine for prevention of cisplatin-induced vomiting].
Topics: Adult; Antiemetics; Cisplatin; Clonazepam; Dexamethasone; Diphenhydramine; Female; Humans; Metoclopr | 1990 |
Tardive dyskinesia associated with high-dose intravenous metoclopramide.
Topics: Adult; Dyskinesia, Drug-Induced; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Midd | 1986 |
Parkinsonism following i.v. administration of high-dose metoclopramide used as an antiemetic agent during cancer chemotherapy.
Topics: Abdominal Neoplasms; Adenocarcinoma; Aged; Cisplatin; Female; Humans; Metoclopramide; Nausea; Ovaria | 1985 |
High-dose metoclopramide as an antiemetic in patients receiving cis-platinum-based combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diarrhea; Female; Humans; Male; Metoclopr | 1985 |