metoclopramide has been researched along with Bilateral Headache in 35 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subjects in both the metoclopramide and ibuprofen arms reported reduced headache severity and nausea compared to pretreatment values at 120 min." | 9.34 | Prospective Double-Blinded Randomized Field-Based Clinical Trial of Metoclopramide and Ibuprofen for the Treatment of High Altitude Headache and Acute Mountain Sickness. ( Bhai, SF; Gregorie, WD; Harris, NS; Irons, HR; Salas, RN, 2020) |
| "In this small randomized study, intranasal ketamine was not superior to standard therapy among ED patients with primary headache syndromes." | 9.30 | The THINK (Treatment of Headache with Intranasal Ketamine) Trial: A Randomized Controlled Trial Comparing Intranasal Ketamine with Intravenous Metoclopramide. ( April, MD; Benish, T; Casmaer, M; Hunter, CJ; Love, S; Summers, SM; Villalobos, D, 2019) |
| "MAD effectively relieves headaches in pregnant women when acetaminophen fails." | 9.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "We compare metoclopramide 20 mg intravenously, combined with diphenhydramine 25 mg intravenously, with ketorolac 30 mg intravenously in adults with tension-type headache and all nonmigraine, noncluster recurrent headaches." | 9.17 | A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches. ( Adewunmi, V; Bijur, PE; Campbell, C; Esses, D; Friedman, BW; Gallagher, EJ; Solorzano, C, 2013) |
| "The potent serotonin receptor (5-HT3) antagonists are new highly selective agents for the prevention and control of chemotherapy-induced nausea and vomiting that have been shown to be comparable to or more effective than traditional metoclopramide regimens." | 9.08 | A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy. ( Bastit, P; Cals, L; Cappelaere, P; Catimel, G; Chevallier, B; Claverie, N; Fabbro, M; Giovannini, M; Khayat, D; Splinter, T; Wendling, JL, 1997) |
| " Oral granisetron alone was as effective as met/dex in control of acute emesis in all parameters examined." | 9.07 | Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group. ( Cedar, E; Cunningham, J; Goedhals, L; Heron, JF; Jordaan, JP, 1994) |
| " A sample of 43 patients with breast cancer was accrued from September to November 1992 in a phase II study to assess the efficacy of granisetron in patients receiving FEC (5-FU, epirubicin, cyclophosphamide)." | 9.07 | Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide. ( Ang, PT; Khoo, KS; Tan, EH, 1994) |
| "To compare the efficacy and frequency of akathisia and dystonia between the dopamine antagonist headache medications olanzapine, metoclopramide and prochlorperazine." | 8.31 | Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023) |
| "Monosodium glutamate induces behaviors thought to reflect headache and nausea in rats." | 8.12 | Peripheral N-methyl-D-aspartate receptor activation contributes to monosodium glutamate-induced headache but not nausea behaviours in rats. ( Benbow, T; Cairns, BE; Exposto, FG; Sheikhi, A; Svensson, P; Teja, F, 2022) |
| "Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation." | 7.71 | Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002) |
| "Headache is one of the most common neurological conditions among emergency department visits (ED), although the best therapy has not been identified yet." | 7.01 | Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches. ( Eslami, K; Kouti, L; Majdinasab, N; Motamed, H; Soltani, KM, 2021) |
| " We hypothesized that dexamethasone 16 mg IV would allow greater rates of sustained headache relief than 4 mg when coadministered with metoclopramide 10 mg IV." | 5.69 | Randomized Trial Comparing Low- vs High-Dose IV Dexamethasone for Patients With Moderate to Severe Migraine. ( Adler, N; Cain, D; Feliciano, C; Friedman, BW; Irizarry, E; Kessler, BD; Lutz, CL; Martorello, K; Moss, H; Solorzano, C, 2023) |
| "The objective of this study was to assess the efficacy and safety of a common monotherapy (intravenous [iv] metoclopramide) compared to a combination strategy (adding iv ketorolac to metoclopramide) in children presenting for acute treatment of migraine headache in the emergency department (ED)." | 5.51 | A randomized trial of ketorolac and metoclopramide for migraine in the emergency department. ( Ali, S; Johnson, DW; Newton, AS; Richer, LP; Rosychuk, RJ; Rowe, BH, 2022) |
| "Metoclopramide (MCP) is a commonly used anti-emetic in the emergency department (ED)." | 5.48 | Metoclopramide induced pheochromocytoma crisis. ( Kim, HK; Leonard, JB; Munir, KM, 2018) |
| "This review found insufficient evidence to recommend the use of diphenhydramine as an adjunct therapy to prevent akathisia in ED patients treated with neuroleptics or metoclopramide for primary headache." | 5.41 | Adjuvant anticholinergic therapy for the prevention of akathisia in patients with primary headache in the emergency department: A systematic review. ( Campbell, S; Kirkland, SW; Meyer, J; Rowe, BH; Villa-Roel, C, 2023) |
| " Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need." | 5.41 | The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023) |
| "Subjects in both the metoclopramide and ibuprofen arms reported reduced headache severity and nausea compared to pretreatment values at 120 min." | 5.34 | Prospective Double-Blinded Randomized Field-Based Clinical Trial of Metoclopramide and Ibuprofen for the Treatment of High Altitude Headache and Acute Mountain Sickness. ( Bhai, SF; Gregorie, WD; Harris, NS; Irons, HR; Salas, RN, 2020) |
| "In this small randomized study, intranasal ketamine was not superior to standard therapy among ED patients with primary headache syndromes." | 5.30 | The THINK (Treatment of Headache with Intranasal Ketamine) Trial: A Randomized Controlled Trial Comparing Intranasal Ketamine with Intravenous Metoclopramide. ( April, MD; Benish, T; Casmaer, M; Hunter, CJ; Love, S; Summers, SM; Villalobos, D, 2019) |
| "MAD effectively relieves headaches in pregnant women when acetaminophen fails." | 5.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "To compare effectiveness of "oxygen alone" vs "metoclopramide plus oxygen" vs "metamizole plus oxygen" therapy in treating carbon monoxide-induced headache." | 5.22 | Treatment in carbon monoxide poisoning patients with headache: a prospective, multicenter, double-blind, controlled clinical trial. ( Basturk, M; Duran, A; Emet, M; Ocak, T; Serinken, M; Tekin, E, 2016) |
| "We compare metoclopramide 20 mg intravenously, combined with diphenhydramine 25 mg intravenously, with ketorolac 30 mg intravenously in adults with tension-type headache and all nonmigraine, noncluster recurrent headaches." | 5.17 | A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches. ( Adewunmi, V; Bijur, PE; Campbell, C; Esses, D; Friedman, BW; Gallagher, EJ; Solorzano, C, 2013) |
| "The potent serotonin receptor (5-HT3) antagonists are new highly selective agents for the prevention and control of chemotherapy-induced nausea and vomiting that have been shown to be comparable to or more effective than traditional metoclopramide regimens." | 5.08 | A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy. ( Bastit, P; Cals, L; Cappelaere, P; Catimel, G; Chevallier, B; Claverie, N; Fabbro, M; Giovannini, M; Khayat, D; Splinter, T; Wendling, JL, 1997) |
| " Oral granisetron alone was as effective as met/dex in control of acute emesis in all parameters examined." | 5.07 | Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group. ( Cedar, E; Cunningham, J; Goedhals, L; Heron, JF; Jordaan, JP, 1994) |
| " A sample of 43 patients with breast cancer was accrued from September to November 1992 in a phase II study to assess the efficacy of granisetron in patients receiving FEC (5-FU, epirubicin, cyclophosphamide)." | 5.07 | Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide. ( Ang, PT; Khoo, KS; Tan, EH, 1994) |
| "To compare the efficacy and frequency of akathisia and dystonia between the dopamine antagonist headache medications olanzapine, metoclopramide and prochlorperazine." | 4.31 | Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023) |
| "Monosodium glutamate induces behaviors thought to reflect headache and nausea in rats." | 4.12 | Peripheral N-methyl-D-aspartate receptor activation contributes to monosodium glutamate-induced headache but not nausea behaviours in rats. ( Benbow, T; Cairns, BE; Exposto, FG; Sheikhi, A; Svensson, P; Teja, F, 2022) |
| "Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation." | 3.71 | Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002) |
| "Headache is one of the most common neurological conditions among emergency department visits (ED), although the best therapy has not been identified yet." | 3.01 | Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches. ( Eslami, K; Kouti, L; Majdinasab, N; Motamed, H; Soltani, KM, 2021) |
| "Headaches affect 88% of reproductive-aged women." | 2.72 | Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review. ( Bushman, ET; Cozzi, G; Digre, K; Sinkey, RG; Smith, CH; Varner, MW, 2021) |
| " Only one adverse event, headache, occurred in more than five patients in the granisetron group." | 2.67 | Efficacy and safety of granisetron compared with high-dose metoclopramide plus dexamethasone in patients receiving high-dose cisplatin in a single-blind study. The Granisetron Study Group. ( Chevallier, B, 1990) |
| " Successful treatment requires adequate dosing plus choosing the optimal route for drug delivery." | 2.40 | Management of an acute primary headache. ( Ward, TN, 1998) |
| "Metoclopramide (MCP) is a commonly used anti-emetic in the emergency department (ED)." | 1.48 | Metoclopramide induced pheochromocytoma crisis. ( Kim, HK; Leonard, JB; Munir, KM, 2018) |
| "A higher percentage of patients with migraine compared with those with tension headache were either symptom-free or had only slight residual headache on leaving." | 1.26 | Observations on the treatment of an acute attack of migraine. ( Leyton, M; Wilkinson, M; Williams, K, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.43) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 2 (5.71) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 13 (37.14) | 2.80 |
| Authors | Studies |
|---|---|
| Soltani, KM | 1 |
| Motamed, H | 1 |
| Eslami, K | 1 |
| Majdinasab, N | 1 |
| Kouti, L | 1 |
| Chowdhury, SS | 1 |
| Shaw, M | 1 |
| Berezowski, I | 1 |
| Abdelmonem, A | 1 |
| Patel, J | 1 |
| Atif, H | 1 |
| McGhee, J | 1 |
| Richer, LP | 1 |
| Ali, S | 1 |
| Johnson, DW | 1 |
| Rosychuk, RJ | 1 |
| Newton, AS | 1 |
| Rowe, BH | 3 |
| Meyer, J | 1 |
| Kirkland, SW | 1 |
| Campbell, S | 1 |
| Villa-Roel, C | 2 |
| Benbow, T | 1 |
| Teja, F | 1 |
| Sheikhi, A | 1 |
| Exposto, FG | 1 |
| Svensson, P | 1 |
| Cairns, BE | 1 |
| Chinn, E | 1 |
| Brunette, ND | 1 |
| Driver, BE | 1 |
| Klein, LR | 1 |
| Stang, JL | 1 |
| DeVries, P | 1 |
| Mojica, E | 1 |
| Raiter, A | 1 |
| Miner, JR | 1 |
| Cole, JB | 1 |
| Abdelmonem, H | 1 |
| Abdelhay, HM | 1 |
| Abdelwadoud, GT | 1 |
| Alhosini, ANM | 1 |
| Ahmed, AE | 1 |
| Mohamed, SW | 1 |
| Al-Dardery, NM | 1 |
| Abd-ElGawad, M | 1 |
| Kamel, MA | 1 |
| Kuan, WS | 1 |
| Kumar, R | 1 |
| Yau, YW | 1 |
| Ng, WM | 1 |
| Chia, DWJ | 1 |
| Ng, EY | 1 |
| Lather, KS | 1 |
| Chua, MT | 1 |
| Friedman, BW | 2 |
| Solorzano, C | 2 |
| Kessler, BD | 1 |
| Martorello, K | 1 |
| Lutz, CL | 1 |
| Feliciano, C | 1 |
| Adler, N | 1 |
| Moss, H | 1 |
| Cain, D | 1 |
| Irizarry, E | 1 |
| Irons, HR | 1 |
| Salas, RN | 1 |
| Bhai, SF | 1 |
| Gregorie, WD | 1 |
| Harris, NS | 1 |
| Bushman, ET | 1 |
| Cozzi, G | 1 |
| Sinkey, RG | 1 |
| Smith, CH | 1 |
| Varner, MW | 1 |
| Digre, K | 1 |
| Wells, S | 1 |
| Stiell, IG | 1 |
| Vishnyakova, E | 1 |
| Lun, R | 1 |
| Nemnom, MJ | 1 |
| Perry, JJ | 1 |
| Leonard, JB | 1 |
| Munir, KM | 1 |
| Kim, HK | 1 |
| Childress, KMS | 1 |
| Dothager, C | 1 |
| Gavard, JA | 1 |
| Lebovitz, S | 1 |
| Laska, C | 1 |
| Mostello, DJ | 1 |
| Smith, JH | 1 |
| Potter, JL | 1 |
| Robblee, JV | 1 |
| Benish, T | 1 |
| Villalobos, D | 1 |
| Love, S | 1 |
| Casmaer, M | 1 |
| Hunter, CJ | 1 |
| Summers, SM | 1 |
| April, MD | 1 |
| Goodnough, R | 1 |
| Krebs, LD | 1 |
| Adewunmi, V | 1 |
| Campbell, C | 1 |
| Esses, D | 1 |
| Bijur, PE | 1 |
| Gallagher, EJ | 1 |
| Ocak, T | 1 |
| Tekin, E | 1 |
| Basturk, M | 1 |
| Duran, A | 1 |
| Serinken, M | 1 |
| Emet, M | 1 |
| Lalla, R | 1 |
| Malhotra, HS | 1 |
| Garg, RK | 1 |
| Verma, R | 1 |
| Royer, B | 1 |
| Ziegler, F | 1 |
| Muret, P | 1 |
| Davani, S | 1 |
| Kantelip, JP | 1 |
| Kabbouche, MA | 1 |
| Linder, SL | 1 |
| Blau, JN | 1 |
| Heron, JF | 1 |
| Goedhals, L | 1 |
| Jordaan, JP | 1 |
| Cunningham, J | 1 |
| Cedar, E | 1 |
| Tan, EH | 1 |
| Ang, PT | 1 |
| Khoo, KS | 1 |
| McBeath, JG | 1 |
| Nanda, A | 1 |
| Chevallier, B | 2 |
| Cappelaere, P | 1 |
| Splinter, T | 1 |
| Fabbro, M | 1 |
| Wendling, JL | 1 |
| Cals, L | 1 |
| Catimel, G | 1 |
| Giovannini, M | 1 |
| Khayat, D | 1 |
| Bastit, P | 1 |
| Claverie, N | 1 |
| Ward, TN | 1 |
| Olesen, J | 1 |
| Aebelholt, A | 1 |
| Veilis, B | 1 |
| Wilkinson, M | 1 |
| Williams, K | 1 |
| Leyton, M | 1 |
| Spierings, EL | 1 |
| Kreel, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An RCT of Metoclopramide/Diphenhydramine vs. Ketorolac Alone for Tension-type Headache[NCT01011673] | Phase 4 | 123 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031] | Phase 4 | 54 participants (Actual) | Interventional | 2016-03-17 | Completed | ||
| A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872] | Phase 4 | 500 participants (Actual) | Interventional | 2017-09-05 | Terminated (stopped due to no longer recruiting or studying) | ||
| Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130] | Phase 4 | 58 participants (Actual) | Interventional | 2017-05-16 | Completed | ||
| A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache[NCT02440997] | 46 participants (Actual) | Interventional | 2015-03-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
At baseline at at 60 minutes, all patients were asked to describe their pain on a scale from 0 to 10, with 0 representing no pain and 10 the worst imaginable. The primary outcome is the 60 minute score subtracted from the baseline score (NCT01011673)
Timeframe: Baseline, 60 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketorolac | 3.8 |
| Metoclopramide | 5.1 |
"24 hours after the emergency department visit, patients were asked, The next time you come to the Er with this type of headache, do you want to receive the same medication? Affirmative answers are tabulated here." (NCT01011673)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketorolac | 45 |
| Metoclopramide | 53 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 33.7 |
| Study Arm | 21.2 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 63.5 |
| Study Arm | 43.5 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 38.9 |
| Study Arm | 22.9 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 2 |
| Study Arm | 3 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 3 |
| Study Arm | 3 |
6 reviews available for metoclopramide and Bilateral Headache
| Article | Year |
|---|---|
Adjuvant anticholinergic therapy for the prevention of akathisia in patients with primary headache in the emergency department: A systematic review.
Topics: Adult; Antipsychotic Agents; Cholinergic Antagonists; Diphenhydramine; Emergency Service, Hospital; | 2023 |
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea | 2023 |
Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review.
Topics: Acupuncture Analgesia; Analgesics; Biofeedback, Psychology; Codeine; Complementary Therapies; Diphen | 2021 |
Acute treatment of pediatric headache in the emergency department and inpatient settings.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Dihydroergotamine; D | 2005 |
Management of an acute primary headache.
Topics: Acute Disease; Cluster Headache; Dose-Response Relationship, Drug; Drug Administration Routes; Heada | 1998 |
Practical aspects of the pharmacotherapy of headache.
Topics: Analgesics; Antidepressive Agents, Tricyclic; Ergotamine; Headache; Humans; Metoclopramide; Proprano | 1992 |
13 trials available for metoclopramide and Bilateral Headache
| Article | Year |
|---|---|
Randomised trial of IV metoclopramide vs IV ketorolac in treatment of acute primary headaches.
Topics: Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dopamine D2 Receptor An | 2021 |
IV metoclopramide Vs IV ketorolac in the treatment of acute primary headaches: A randomized clinical trial.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Headache; Humans; Ketorola | 2022 |
A randomized trial of ketorolac and metoclopramide for migraine in the emergency department.
Topics: Adolescent; Child; Double-Blind Method; Emergency Service, Hospital; Headache; Humans; Ketorolac; Me | 2022 |
Randomized Trial Comparing Low- vs High-Dose IV Dexamethasone for Patients With Moderate to Severe Migraine.
Topics: Adult; Dexamethasone; Double-Blind Method; Emergency Service, Hospital; Female; Headache; Humans; Me | 2023 |
Prospective Double-Blinded Randomized Field-Based Clinical Trial of Metoclopramide and Ibuprofen for the Treatment of High Altitude Headache and Acute Mountain Sickness.
Topics: Adult; Altitude Sickness; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Cyclooxygenase Inhib | 2020 |
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug A | 2018 |
The THINK (Treatment of Headache with Intranasal Ketamine) Trial: A Randomized Controlled Trial Comparing Intranasal Ketamine with Intravenous Metoclopramide.
Topics: Academic Medical Centers; Administration, Intranasal; Adult; Analgesics; Diphenhydramine; Emergency | 2019 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
A randomized trial of intravenous ketorolac versus intravenous metoclopramide plus diphenhydramine for tension-type and all nonmigraine, noncluster recurrent headaches.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Dopamine Antagonists; Double-Blind | 2013 |
Treatment in carbon monoxide poisoning patients with headache: a prospective, multicenter, double-blind, controlled clinical trial.
Topics: Adult; Analgesics; Carbon Monoxide Poisoning; Carboxyhemoglobin; Combined Modality Therapy; Dipyrone | 2016 |
Oral granisetron alone and in combination with dexamethasone: a double-blind randomized comparison against high-dose metoclopramide plus dexamethasone in prevention of cisplatin-induced emesis. The Granisetron Study Group.
Topics: Administration, Oral; Adult; Aged; Chi-Square Distribution; Cisplatin; Constipation; Dexamethasone; | 1994 |
Control of emesis by intravenous granisetron in breast cancer patients treated with 5-FU, epirubicin and cyclophosphamide.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Constipation; Cyclophosphamide; Epirubicin; Fem | 1994 |
A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy.
Topics: Acute Disease; Alcoholism; Antiemetics; Antineoplastic Agents; Basal Ganglia Diseases; Cisplatin; Do | 1997 |
Efficacy and safety of granisetron compared with high-dose metoclopramide plus dexamethasone in patients receiving high-dose cisplatin in a single-blind study. The Granisetron Study Group.
Topics: Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Headache; Humans; Indazole | 1990 |
16 other studies available for metoclopramide and Bilateral Headache
| Article | Year |
|---|---|
Randomized IV metoclopramide vs IV ketorolac in treatment of acute primary headache.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Headache; Humans; Ketorola | 2022 |
Peripheral N-methyl-D-aspartate receptor activation contributes to monosodium glutamate-induced headache but not nausea behaviours in rats.
Topics: Amino Acids; Animals; Aspartic Acid; Female; Glutamic Acid; Headache; Kynurenic Acid; Male; Metoclop | 2022 |
Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients.
Topics: Cohort Studies; Double-Blind Method; Dystonia; Emergency Service, Hospital; Headache; Humans; Metocl | 2023 |
Headache in the Emergency Department: A Multicenter Observational Study from Singapore.
Topics: Adult; Cross-Sectional Studies; Emergency Service, Hospital; Female; Headache; Humans; Male; Metoclo | 2023 |
Optimal management strategies for primary headache in the emergency department.
Topics: Adult; Emergency Service, Hospital; Female; Headache; Humans; Ketorolac; Metoclopramide; Migraine Di | 2021 |
Metoclopramide induced pheochromocytoma crisis.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Antiemetics; Emergency Medical Services; Female; Head | 2018 |
What Is the Optimal Placebo for Clinical Trials of Nerve Blocks in Headache?: An N-of-1 Study of Lactated Ringer's.
Topics: Bupivacaine; Emergency Service, Hospital; Headache; Humans; Metoclopramide; Migraine Disorders; Nerv | 2019 |
THINK of Ketamine for Headache.
Topics: Administration, Intravenous; Analgesics; Headache; Humans; Ketamine; Metoclopramide | 2019 |
How to diagnose and treat benign headaches.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dopamine D2 Receptor Antagonists; Drug Thera | 2019 |
Conservative management in a rare case of spontaneous bilateral cerebellar haemorrhage.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetazolamide; Adult; Antiemetics; Cerebellum; Diuretics, O | 2012 |
Acitretin-associated thrombotic stroke.
Topics: Acitretin; Analgesics; Anticoagulants; Antiemetics; Dextropropoxyphene; Domperidone; Female; Headach | 2002 |
A plain man's guide to the management of migraine.
Topics: Acetaminophen; Aspirin; Ergotamine; Headache; Humans; Metoclopramide; Migraine Disorders; Sleep | 1982 |
Use of dihydroergotamine in patients with postconcussion syndrome.
Topics: Adult; Brain Concussion; Dihydroergotamine; Drug Therapy, Combination; Female; Headache; Humans; Mal | 1994 |
The Copenhagen Acute Headache Clinic: organization, patient material and treatment results.
Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Anti-Anxiety Agents; Biperiden; Denmark; Female; | 1979 |
Observations on the treatment of an acute attack of migraine.
Topics: Acute Disease; Analgesics; Diazepam; Ergotamine; Female; Headache; Humans; Hypnotics and Sedatives; | 1978 |
The use of metoclopramide in radiology.
Topics: Barium Sulfate; Digestive System; Gastrointestinal Motility; Headache; Humans; Metoclopramide; Radio | 1973 |