Page last updated: 2024-10-31

metoclopramide and Autoimmune Diabetes

metoclopramide has been researched along with Autoimmune Diabetes in 30 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"A double-blind, multicenter, randomized trial was conducted to compare the side effects and efficacy of domperidone and metoclopramide in symptomatic diabetic gastroparesis."9.09A double-blind multicenter comparison of domperidone and metoclopramide in the treatment of diabetic patients with symptoms of gastroparesis. ( Abell, T; Barnett, J; Koch, K; Patterson, D; Rothstein, R, 1999)
"A double-blind, multicenter, randomized trial was conducted to compare the side effects and efficacy of domperidone and metoclopramide in symptomatic diabetic gastroparesis."5.09A double-blind multicenter comparison of domperidone and metoclopramide in the treatment of diabetic patients with symptoms of gastroparesis. ( Abell, T; Barnett, J; Koch, K; Patterson, D; Rothstein, R, 1999)
" the proportional cumulative area under the curve of paracetamol) was utilized in diabetic patients in order to detect both gastroparesis and the influence of metoclopramide, a known prokinetic drug, on this condition."5.08The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. ( Moncrieff, J; Snyman, JR; Sommers, DK; van Wyk, M, 1995)
"We evaluated whether chronic nausea and vomiting in diabetic patients correlate with abnormal gastric emptying of liquid or solid, or both liquid and solid, radiolabeled meals and recorded the acute effects of metoclopramide."3.67Gastric emptying in patients with diabetes mellitus. ( Kalbfleisch, JH; Loo, FD; Palmer, DW; Soergel, KH; Wood, CM, 1984)
" These results indicate that single-dose cisapride increases esophageal emptying in insulin-dependent diabetics and that chronic administration of cisapride is effective in the treatment of diabetic gastroparesis."2.66Effect of cisapride on gastric and esophageal emptying in insulin-dependent diabetes mellitus. ( Chatterton, BE; Harding, PE; Horowitz, M; Maddern, GJ; Maddox, A; Shearman, DJ; Wishart, J, 1987)
"Metoclopramide may cause reversible nonthrombocytopenic vascular-type palpable purpura."1.30Reversible nonthrombocytopenic palpable purpura associated with metoclopramide. ( Goad, JA, 1999)
"Vomiting was the first cause of admission in diabetics."1.29Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. ( Gallar, P; Guijo, G; Oliet, A; Ortega, O; Vigil, A, 1993)
"In 10 patients with IDDM and 8 controls the short-term variations in pituitary hormones and blood glucose concentration were evaluated."1.27Possible altered dopaminergic modulation of pituitary function in normal-menstruating women with insulin dependent diabetes mellitus (IDDM). ( Andersen, AN; Carstensen, L; Djursing, H; Hagen, C, 1984)
"Metoclopramide tablets have been approved for use in the acute and chronic management of diabetic gastroparesis."1.27Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis. ( Dugas, MC; Gavaler, JS; Lhotsky, DM; Schade, RR; Van Thiel, DH, 1985)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199018 (60.00)18.7374
1990's10 (33.33)18.2507
2000's2 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jellish, WS1
Kartha, V1
Fluder, E1
Slogoff, S1
Djursing, H4
Carstensen, L2
Hagen, C4
Andersen, AN4
Volpi, R3
Coiro, V3
Castelli, A1
Cappagli, M1
Muzzetto, P1
Sciarra, A1
Chiodera, P3
Loo, FD1
Palmer, DW1
Soergel, KH1
Kalbfleisch, JH1
Wood, CM1
Battle, WM1
Snape, WJ1
Alavi, A1
Cohen, S1
Braunstein, S1
Capretti, L2
Speroni, G2
Caffarri, G1
Colla, R1
Caiazza, A2
Hüppe, D1
Tromm, A1
Tegenthoff, M1
Faig, J1
Brunke, F1
Depka, S1
May, B1
Gallar, P1
Oliet, A1
Vigil, A1
Ortega, O1
Guijo, G1
van Wyk, M1
Sommers, DK1
Snyman, JR1
Moncrieff, J1
Durant, S1
Alves, V1
Coulaud, J1
El Hasnaoui, A1
Dardenne, M1
Homo-Delarche, F1
Goad, JA1
la Marca, A1
Morgante, G1
De Leo, V1
Patterson, D1
Abell, T1
Rothstein, R1
Koch, K1
Barnett, J1
Murphy, EJ1
Hartong, WA1
Moore, J1
Booth, JP1
Sewell, DD1
Yoshinobu, BH1
Caligiuri, MP1
Jeste, DV1
Rossi, G1
Bianconi, L1
Boesgaard, S1
Fenger, M1
Prelević, GM1
Würzburger, MI1
Perić, LA1
Vogelberg, KH1
Dalügge, A1
Chaudhuri, TK1
Fink, S1
Burger, R1
Palmer, JD1
Skvor, J1
Ondrej, J1
Horowitz, M1
Maddox, A1
Harding, PE1
Maddern, GJ1
Chatterton, BE1
Wishart, J1
Shearman, DJ1
Friedman, LS1
Weinrauch, LA1
D'Elia, JA1
Trapnell, BC1
Mavko, LE1
Birskovich, LM1
Falko, JM1
Ricci, DA1
Saltzman, MB1
Meyer, C1
Callachan, C1
McCallum, RW1
Petersen, K2
Schade, RR1
Dugas, MC1
Lhotsky, DM1
Gavaler, JS1
Van Thiel, DH1
Achem-Karam, SR1
Funakoshi, A1
Vinik, AI1
Owyang, C1
Christensen, NJ1
Tvede, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ultrasound Evaluation of Gastric Content in Diabetic and Non-Diabetic Term Pregnant Women: An Observational Study[NCT05959135]80 participants (Actual)Observational2023-07-26Completed
A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622]Phase 23 participants (Actual)Interventional2014-07-31Terminated (stopped due to Lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for metoclopramide and Autoimmune Diabetes

ArticleYear
Effect of metoclopramide on gastric fluid volumes in diabetic patients who have fasted before elective surgery.
    Anesthesiology, 2005, Volume: 102, Issue:5

    Topics: Aged; Anesthesia, General; Body Fluids; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Melli

2005
Influence of residual C-peptide secretion on the arginine vasopressin response to hypoglycaemia and metoclopramide in insulin-dependent diabetes.
    European journal of clinical investigation, 1995, Volume: 25, Issue:8

    Topics: Adult; Antiemetics; Arginine Vasopressin; C-Peptide; Diabetes Mellitus, Type 1; Humans; Hypoglycemia

1995
The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:9

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetes Mellitus, Type 1; Diabetic Neuropathi

1995
A double-blind multicenter comparison of domperidone and metoclopramide in the treatment of diabetic patients with symptoms of gastroparesis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:5

    Topics: Adult; Aged; Antiemetics; Diabetes Mellitus, Type 1; Domperidone; Dopamine Antagonists; Double-Blind

1999
Effect of cisapride on gastric and esophageal emptying in insulin-dependent diabetes mellitus.
    Gastroenterology, 1987, Volume: 92, Issue:6

    Topics: Adult; Blood Glucose; Cisapride; Diabetes Mellitus, Type 1; Esophagus; Female; Gastric Emptying; Hum

1987
Effect of metoclopramide in diabetic gastroparesis.
    Journal of clinical gastroenterology, 1985, Volume: 7, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-

1985

Other Studies

24 other studies available for metoclopramide and Autoimmune Diabetes

ArticleYear
Possible altered dopaminergic modulation of pituitary function in normal-menstruating women with insulin dependent diabetes mellitus (IDDM).
    Acta endocrinologica, 1984, Volume: 107, Issue:4

    Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Estradiol; Female; Follicle Stimulating Hormone; Go

1984
Different effects of metoclopramide and domperidone on GH release in type I male diabetics.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16 Suppl 1

    Topics: Adult; Blood-Brain Barrier; Diabetes Mellitus, Type 1; Domperidone; Dopamine; Growth Hormone; Humans

1984
Gastric emptying in patients with diabetes mellitus.
    Gastroenterology, 1984, Volume: 86, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 1; Female; Food; Gastric Emptying; Humans; Male; Metoclopramide; Midd

1984
Colonic dysfunction in diabetes mellitus.
    Gastroenterology, 1980, Volume: 79, Issue:6

    Topics: Action Potentials; Adolescent; Adult; Colon; Constipation; Diabetes Mellitus; Diabetes Mellitus, Typ

1980
[Acute effect of metoclopramide on esophagus motility in diabetes mellitus].
    Deutsche medizinische Wochenschrift (1946), 1993, Aug-27, Volume: 118, Issue:34-35

    Topics: Adult; Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Esophagoga

1993
Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1993, Volume: 13 Suppl 2

    Topics: Cisapride; Diabetes Mellitus, Type 1; Erythromycin; Female; Gastric Emptying; Hospitalization; Human

1993
Attempts to pharmacologically modulate prolactin levels and type 1 autoimmune diabetes in the non-obese diabetic (NOD) mouse.
    Journal of autoimmunity, 1995, Volume: 8, Issue:6

    Topics: Animals; Blood Glucose; Bromocriptine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; D

1995
Reversible nonthrombocytopenic palpable purpura associated with metoclopramide.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:1

    Topics: Abdominal Pain; Aged; Diabetes Mellitus, Type 1; Humans; IgA Vasculitis; Male; MEDLINE; Metocloprami

1999
Evaluation of hypothalamic-pituitary-adrenal axis in amenorrhoeic women with insulin-dependent diabetes.
    Human reproduction (Oxford, England), 1999, Volume: 14, Issue:2

    Topics: Adult; Amenorrhea; Circadian Rhythm; Corticotropin-Releasing Hormone; Diabetes Mellitus, Type 1; Fem

1999
Intra-arterial injection of metoclopramide, midazolam, propofol and pethidine.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:3

    Topics: Abdominal Wall; Adolescent; Anesthesia, General; Diabetes Mellitus, Type 1; Drug Therapy, Combinatio

2002
Metoclopramide in diabetic gastroparesis.
    Annals of internal medicine, 1977, Volume: 86, Issue:6

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastrointestinal Motility; Humans;

1977
Metoclopramide-associated tardive dyskinesia in hemodialysis patients with diabetes mellitus. Two case reports.
    General hospital psychiatry, 1992, Volume: 14, Issue:6

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dyskinesia, Drug-Induced; Humans; Male; Me

1992
Abnormal arginine-vasopressin responses to metoclopramide and insulin-induced hypoglycemia in type I diabetes mellitus.
    Hormone research, 1990, Volume: 33, Issue:6

    Topics: Adult; Arginine Vasopressin; Blood Glucose; Diabetes Mellitus, Type 1; Hematocrit; Humans; Hypoglyce

1990
Cortisol secretion in patients with normoprolactinemic amenorrhea.
    Acta endocrinologica, 1988, Volume: 118, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Amenorrhea; Diabetes Mellitus, Type 1; Female; Humans; Hydrocort

1988
Blunted prolactin response to metoclopramide in insulin-dependent diabetic patients with secondary amenorrhoea.
    Archives of gynecology and obstetrics, 1987, Volume: 241, Issue:3

    Topics: Adult; Amenorrhea; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Follicle Stimulating

1987
[Sonographic studies during drug treatment of diabetic gastroparesis].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-16, Volume: 113, Issue:24

    Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro

1988
The effect of metoclopramide treatment on diabetic cystoparesis.
    JAMA, 1988, Mar-18, Volume: 259, Issue:11

    Topics: Diabetes Mellitus, Type 1; Humans; Male; Metoclopramide; Middle Aged; Urinary Bladder Diseases

1988
[Prolactin in children].
    Ceskoslovenska pediatrie, 1987, Volume: 42, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Gynecomastia; Humans; Infant

1987
Metoclopramide-induced neuroleptic malignant syndrome.
    Archives of internal medicine, 1987, Volume: 147, Issue:8

    Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Metoclopramide; Nausea; Neuroleptic Malignant Synd

1987
Metoclopramide suppositories in the treatment of diabetic gastroparesis.
    Archives of internal medicine, 1986, Volume: 146, Issue:11

    Topics: Adult; Diabetes Mellitus, Type 1; Female; Gastric Emptying; Humans; Metoclopramide; Stomach Diseases

1986
Gonadotropin secretion before and during acute and chronic dopamine-receptor blockade in insulin-dependent diabetic patients with amenorrhea.
    Fertility and sterility, 1985, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Amenorrhea; Diabetes Mellitus, Type 1; Estradiol; Female; Follicle Stimulating Ho

1985
Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gastric Emptying; Humans; Kidney Failure, C

1985
Plasma motilin concentration and interdigestive migrating motor complex in diabetic gastroparesis: effect of metoclopramide.
    Gastroenterology, 1985, Volume: 88, Issue:2

    Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Duodenum; Female; Gastrointestinal Hormones; Gastroint

1985
Abnormal conjugated dopamine levels in patients with normoprolactinaemic amenorrhoea and in insulin-dependent diabetic patients.
    Scandinavian journal of clinical and laboratory investigation, 1985, Volume: 45, Issue:5

    Topics: Adult; Amenorrhea; Catecholamines; Diabetes Mellitus, Type 1; Dopamine; Female; Humans; Metocloprami

1985