metoclopramide has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 24 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " the proportional cumulative area under the curve of paracetamol) was utilized in diabetic patients in order to detect both gastroparesis and the influence of metoclopramide, a known prokinetic drug, on this condition." | 5.08 | The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. ( Moncrieff, J; Snyman, JR; Sommers, DK; van Wyk, M, 1995) |
| "Metoclopramide hydrochloride was administered to nine children for the treatment of gastric stasis (N=6) and unexplained vomiting (N=3)." | 3.66 | Enhanced gastroduodenal motility in children. ( Hitch, DC; Torres-Pinedo, RB; Vanhoutte, JJ, 1982) |
| "Diabetic gastroparesis is defined as delayed gastric emptying without mechanical obstruction in the setting of diabetes." | 2.72 | Diabetic gastroparesis: An overview of pathogenesis, clinical presentation and novel therapies, with a focus on ghrelin receptor agonists. ( Baker, C; Petri, M; Rasouli, N; Singh, I; Underkofler, C, 2021) |
| " While both cisapride and metoclopramide normalized impaired solid emptying, cisapride at its highest dosage (10 mg) resulted in significantly faster gastric emptying (P = 0." | 2.67 | Cisapride vs metoclopramide. An acute study in diabetic gastroparesis. ( Diamant, NE; Lico, S; McHugh, S, 1992) |
| "Metoclopramide tablets have been approved for use in the acute and chronic management of diabetic gastroparesis." | 1.27 | Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis. ( Dugas, MC; Gavaler, JS; Lhotsky, DM; Schade, RR; Van Thiel, DH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (70.83) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Petri, M | 1 |
| Singh, I | 1 |
| Baker, C | 1 |
| Underkofler, C | 1 |
| Rasouli, N | 1 |
| Gajendran, M | 1 |
| Sarosiek, I | 1 |
| McCallum, R | 1 |
| Jellish, WS | 1 |
| Kartha, V | 1 |
| Fluder, E | 1 |
| Slogoff, S | 1 |
| Valenzuela, JE | 1 |
| Dooley, CP | 1 |
| Bessa, AM | 1 |
| Zanella, MT | 1 |
| Saragoça, MA | 1 |
| Mulinari, RA | 1 |
| Czepielewski, M | 1 |
| Ribeiro, AB | 1 |
| Ramos, OL | 1 |
| Feldman, M | 1 |
| Schiller, LR | 1 |
| Hitch, DC | 1 |
| Vanhoutte, JJ | 1 |
| Torres-Pinedo, RB | 1 |
| Fox, S | 1 |
| Behar, J | 1 |
| Erbas, T | 1 |
| Varoglu, E | 1 |
| Erbas, B | 1 |
| Tastekin, G | 1 |
| Akalin, S | 1 |
| Hüppe, D | 1 |
| Tromm, A | 1 |
| Tegenthoff, M | 1 |
| Faig, J | 1 |
| Brunke, F | 1 |
| Depka, S | 1 |
| May, B | 1 |
| van Wyk, M | 1 |
| Sommers, DK | 1 |
| Snyman, JR | 1 |
| Moncrieff, J | 1 |
| Longstreth, GF | 1 |
| Malagelada, JR | 1 |
| Kelly, KA | 1 |
| Hartong, WA | 1 |
| Moore, J | 1 |
| Booth, JP | 1 |
| Campbell, IW | 1 |
| Heading, RC | 2 |
| Tothill, P | 2 |
| Buist, TA | 1 |
| Ewing, DJ | 2 |
| Clarke, BF | 2 |
| Brady, PG | 1 |
| Richardson, R | 1 |
| McHugh, S | 1 |
| Lico, S | 1 |
| Diamant, NE | 1 |
| de Caestecker, JS | 1 |
| Champion, MC | 1 |
| Vogelberg, KH | 1 |
| Dalügge, A | 1 |
| Smout, AJ | 1 |
| Bernstein, G | 1 |
| Rifkin, H | 1 |
| Wright, RA | 1 |
| Clemente, R | 1 |
| Wathen, R | 1 |
| Schade, RR | 1 |
| Dugas, MC | 1 |
| Lhotsky, DM | 1 |
| Gavaler, JS | 1 |
| Van Thiel, DH | 1 |
| Adams, CD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ultrasound Evaluation of Gastric Content in Diabetic and Non-Diabetic Term Pregnant Women: An Observational Study[NCT05959135] | 80 participants (Actual) | Observational | 2023-07-26 | Completed | |||
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for metoclopramide and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Diabetic gastroparesis: An overview of pathogenesis, clinical presentation and novel therapies, with a focus on ghrelin receptor agonists.
Topics: Diabetes Mellitus; Diabetic Neuropathies; Gastric Emptying; Gastroparesis; Humans; Metoclopramide; Q | 2021 |
Metoclopramide nasal spray for management of symptoms of acute and recurrent diabetic gastroparesis in adults.
Topics: Diabetes Mellitus; Diabetic Neuropathies; Gastroparesis; Humans; Metoclopramide; Nasal Sprays; Treat | 2021 |
Dopamine antagonists in the upper gastrointestinal tract.
Topics: Diabetic Neuropathies; Digestive System; Domperidone; Dopamine Antagonists; Duodenum; Dyspepsia; Eso | 1984 |
Disorders of gastrointestinal motility associated with diabetes mellitus.
Topics: Autonomic Nervous System Diseases; Bethanechol Compounds; Constipation; Diabetes Complications; Diab | 1983 |
Management of idiopathic, diabetic and miscellaneous gastroparesis with cisapride.
Topics: Cisapride; Clinical Trials as Topic; Diabetic Neuropathies; Domperidone; Gastric Emptying; Humans; M | 1989 |
6 trials available for metoclopramide and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Effect of metoclopramide on gastric fluid volumes in diabetic patients who have fasted before elective surgery.
Topics: Aged; Anesthesia, General; Body Fluids; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Melli | 2005 |
Comparison of metoclopramide and erythromycin in the treatment of diabetic gastroparesis.
Topics: Administration, Oral; Adult; Aged; Diabetic Neuropathies; Dose-Response Relationship, Drug; Erythrom | 1993 |
The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetes Mellitus, Type 1; Diabetic Neuropathi | 1995 |
Cisapride vs metoclopramide. An acute study in diabetic gastroparesis.
Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetic Neuropathies; Dose-Response Relationsh | 1992 |
Evaluation of oral cisapride and metoclopramide in diabetic autonomic neuropathy: an eight-week double-blind crossover study.
Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cisapride; Diabetic Neuropathies; Double-Bl | 1989 |
Management of idiopathic, diabetic and miscellaneous gastroparesis with cisapride.
Topics: Cisapride; Clinical Trials as Topic; Diabetic Neuropathies; Domperidone; Gastric Emptying; Humans; M | 1989 |
14 other studies available for metoclopramide and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Acute hemodynamic and humoral effects of metoclopramide on blood pressure control improvement in subjects with diabetic orthostatic hypotension.
Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Cardiac Output; Diabetes Complications; Dia | 1984 |
Enhanced gastroduodenal motility in children.
Topics: Adolescent; Child; Child, Preschool; Diabetic Neuropathies; Gastrointestinal Motility; Humans; Infan | 1982 |
Pathogenesis of diabetic gastroparesis: a pharmacologic study.
Topics: Adult; Atropine; Bethanechol Compounds; Diabetic Neuropathies; Gastric Emptying; Gastrointestinal Mo | 1980 |
[Acute effect of metoclopramide on esophagus motility in diabetes mellitus].
Topics: Adult; Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Esophagoga | 1993 |
Metoclopramide stimulation of gastric motility and emptying in diabetic gastroparesis.
Topics: Adult; Diabetic Neuropathies; Female; Gastrointestinal Motility; Humans; Metoclopramide; Stomach Dis | 1977 |
Metoclopramide in diabetic gastroparesis.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastrointestinal Motility; Humans; | 1977 |
Gastric emptying in diabetic autonomic neuropathy.
Topics: Adult; Autonomic Nervous System; Diabetic Neuropathies; Gastrointestinal Motility; Humans; Male; Met | 1977 |
Gastric bezoar formation secondary to gastroparesis diabeticorum.
Topics: Autonomic Nervous System; Bezoars; Diabetic Neuropathies; Gastric Emptying; Humans; Male; Metoclopra | 1977 |
[Sonographic studies during drug treatment of diabetic gastroparesis].
Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro | 1988 |
[The significance of disordered gastric emptying].
Topics: Combined Modality Therapy; Diabetic Neuropathies; Duodenal Ulcer; Gastric Emptying; Humans; Metoclop | 1986 |
Diabetes mellitus: gastrointestinal complications.
Topics: Blood Glucose; Cholecystitis; Cholelithiasis; Diabetes Complications; Diabetic Neuropathies; Esophag | 1986 |
Diabetic gastroparesis: an abnormality of gastric emptying of solids.
Topics: Autonomic Nervous System Diseases; Beverages; Blood Glucose; Diabetic Neuropathies; Food; Gastric Em | 1985 |
Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gastric Emptying; Humans; Kidney Failure, C | 1985 |
Metoclopramide and depression.
Topics: Adult; Depression; Diabetic Neuropathies; Drug Administration Schedule; Female; Humans; Male; Metocl | 1985 |