Page last updated: 2024-10-31

metoclopramide and Anxiety

metoclopramide has been researched along with Anxiety in 8 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Methylprednisolone sodium succinate and metoclopramide were compared for their efficacy, tolerance, and safety in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy in patients with cancer."9.06Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy. ( Erlichman, C; Levitt, M; Osoba, D; Pater, JL; Willan, AR, 1986)
"Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn."9.04A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977)
" In addition postoperative morphine requirement, anxiety, and vomiting were not affected by the music during general anesthesia."5.12The impact of music on postoperative pain and anxiety following cesarean section. ( Abul-Qasim, A; Ali, SM; Reza, N; Reza, TH; Saeed, K, 2007)
"Methylprednisolone sodium succinate and metoclopramide were compared for their efficacy, tolerance, and safety in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy in patients with cancer."5.06Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy. ( Erlichman, C; Levitt, M; Osoba, D; Pater, JL; Willan, AR, 1986)
"Since metoclopramide increases lower-esophageal-sphincter pressure in patients with gastroesophageal reflux, we compared the effects of metoclopramide, 10 mg four times daily, with those of placebo on symptoms in 31 patients with chronic heartburn."5.04A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. ( Cooney, C; Ippoliti, AF; McCallum, RW; Sturdevant, RA, 1977)
"When given with pethidine 100 mg or morphine 10 mg as preanaesthetic medication, 10 and 20 mg of metoclopramide cause a reduction in postoperative nausea and vomiting in women undergoing a standard operation with a standard anaesthetic technique."3.65Studies of drugs given before anaesthesia. XXIV: Metocloramide with morphine and pethidine. ( Assaf, RA; Clarke, RS; Dundee, JW; Samuel, IO, 1974)
"Four consecutive trials were undertaken to study lorazepam at each of three dosage levels and diphenhydramine when used in combination with iv metoclopramide and dexamethasone in patients receiving cisplatin at 120 mg/m2."2.66Consecutive dose-finding trials adding lorazepam to the combination of metoclopramide plus dexamethasone: improved subjective effectiveness over the combination of diphenhydramine plus metoclopramide plus dexamethasone. ( Clark, RA; Fiore, JJ; Gralla, RJ; Groshen, S; Kelsen, DP; Kris, MG; Tyson, LB, 1985)
"Metoclopramide also has an important place in the investigation of the role of dopamine in physiological and pathological processes."2.37Metoclopramide--a review. ( Desmond, PV; Watson, KJ, 1986)
" A single dose pharmacokinetic comparison of Gastrobid Continus and Maxolon was carried out perioperatively in two groups of 12 gynaecological patients; each group comprised six patients for major surgery and six patients for minor surgery."1.27A single dose pharmacokinetic study of Gastrobid Continus and Maxolon in the perioperative period. ( Ellis, FR; Madej, TH; Tring, I, 1988)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reza, N1
Ali, SM1
Saeed, K1
Abul-Qasim, A1
Reza, TH1
McCallum, RW1
Ippoliti, AF1
Cooney, C1
Sturdevant, RA1
Madej, TH1
Ellis, FR1
Tring, I1
Venning, M1
Rogers, J1
Desmond, PV1
Watson, KJ1
Osoba, D1
Erlichman, C1
Willan, AR1
Levitt, M1
Pater, JL1
Kris, MG1
Gralla, RJ1
Clark, RA1
Tyson, LB1
Fiore, JJ1
Kelsen, DP1
Groshen, S1
Assaf, RA1
Clarke, RS1
Dundee, JW1
Samuel, IO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Turkish Classical Music on Postpartum Pain and Anxiety in Women Who Delivered Via Cesarean Section[NCT04111575]126 participants (Actual)Interventional2018-02-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for metoclopramide and Anxiety

ArticleYear
Metoclopramide--a review.
    The Medical journal of Australia, 1986, Mar-31, Volume: 144, Issue:7

    Topics: Anxiety; Digestive System; Dopamine Antagonists; Drug Interactions; Female; Gastric Emptying; Gastro

1986

Trials

4 trials available for metoclopramide and Anxiety

ArticleYear
The impact of music on postoperative pain and anxiety following cesarean section.
    Middle East journal of anaesthesiology, 2007, Volume: 19, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anti-Anxiety Agents; Antiemetics; Anxiety; Cesarean

2007
A controlled trial of metoclopramide in symptomatic gastroesophageal reflux.
    The New England journal of medicine, 1977, Feb-17, Volume: 296, Issue:7

    Topics: Antacids; Anxiety; Chronic Disease; Clinical Trials as Topic; Esophagus; Female; Gastroesophageal Re

1977
Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1986, Volume: 9, Issue:4

    Topics: Antineoplastic Agents; Anxiety; Gastrointestinal Diseases; Humans; Methylprednisolone; Methylprednis

1986
Consecutive dose-finding trials adding lorazepam to the combination of metoclopramide plus dexamethasone: improved subjective effectiveness over the combination of diphenhydramine plus metoclopramide plus dexamethasone.
    Cancer treatment reports, 1985, Volume: 69, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Cisplatin; Clinical Trials as

1985

Other Studies

3 other studies available for metoclopramide and Anxiety

ArticleYear
A single dose pharmacokinetic study of Gastrobid Continus and Maxolon in the perioperative period.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:6

    Topics: Adult; Anxiety; Delayed-Action Preparations; Female; Genital Diseases, Female; Humans; Intraoperativ

1988
Continuous subcutaneous infusion: flexible option in symptom control.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1988, Volume: 17, Issue:7

    Topics: Anxiety; Female; Haloperidol; Humans; Infusion Pumps; Infusions, Parenteral; Metoclopramide; Middle

1988
Studies of drugs given before anaesthesia. XXIV: Metocloramide with morphine and pethidine.
    British journal of anaesthesia, 1974, Volume: 46, Issue:7

    Topics: Adult; Anxiety; Female; Humans; Infant, Newborn; Meperidine; Metoclopramide; Morphine; Nausea; Prean

1974