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metoclopramide and Anorexia

metoclopramide has been researched along with Anorexia in 13 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."9.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
"Patients with cancer frequently report gastrointestinal symptoms such as anorexia, early satiety, nausea, vomiting, and bloating."7.80Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation. ( Chow, W; Darke, A; Harsanyi, Z; Marshall, D; Pearen, S; Plourde, JY; Wilson, J; Yoshida, S, 2002)
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."5.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
" Although past attempts to reverse anorexia-cachexia have generally been disappointing, several promising new pharmacologic approaches are currently being evaluated, including megestrol acetate, hydrazine sulfate, metoclopramide, and dronabinol."4.78Management of anorexia-cachexia associated with cancer and HIV infection. ( Gorter, R, 1991)
"Patients with cancer frequently report gastrointestinal symptoms such as anorexia, early satiety, nausea, vomiting, and bloating."3.80Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation. ( Chow, W; Darke, A; Harsanyi, Z; Marshall, D; Pearen, S; Plourde, JY; Wilson, J; Yoshida, S, 2002)
"The effects of the DA receptor antagonists metoclopramide and pimozide on food and water intake in male Sprague Dawley rats were compared to those of domperidone, which does not cross the blood-brain barrier, in an attempt to determine whether any extracerebral DA receptors participate in neuroleptic induced anorexia."3.66Neuroleptic-like anorexia produced by an extra-cerebral DA antagonist. ( Kinchington, PC; Smith, GC; Willis, GL, 1983)
"Thirty-two patients with primary lung cancer receiving combination chemotherapy including cisplatin at a dosage of 80-120 mg/m2 were entered into an antiemetic randomized crossover trial."2.66[Antiemetic effects of combinations of metoclopramide, droperidol and dexamethasone for the prevention of cisplatin-induced gastro-intestinal toxicity: a randomized crossover trial]. ( Fujii, M; Kamei, H; Kiura, K; Okabe, K; Toki, H, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's5 (38.46)18.2507
2000's4 (30.77)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wilson, J1
Plourde, JY1
Marshall, D1
Yoshida, S1
Chow, W1
Harsanyi, Z1
Pearen, S1
Darke, A1
von Meyenburg, C1
Langhans, W1
Hrupka, BJ1
Lelli, G1
Montanari, M1
Gilli, G1
Scapoli, D2
Antonietti, C1
Yavuzsen, T1
Davis, MP1
Walsh, D1
LeGrand, S1
Lagman, R1
Willis, GL1
Smith, GC1
Kinchington, PC1
Kawashima, T1
Wada, T1
Morita, N1
Ohmata, T1
Miyata, K1
Sakamoto, T1
Nelson, KA1
Walsh, TD1
Yoshimura, A1
Yamano, Y1
Gemma, A1
Yoshimori, K1
Hayashihara, K1
Taniguchi, Y1
Uematsu, K1
Shibuya, M1
Kudoh, S1
Niitani, H1
Harrington, ML1
Moore, MP1
Talcott, PA1
Bagley, RS1
Sandmeier, P1
Gorter, R1
Yamamoto, M1
Ujike, H1
Ogawa, N1
Umehara, H1
Sawamura, N1
Takahashi, S1
Kusano, H1
Yokoyama, S1
Suemasu, K1
Fujii, M1
Kiura, K1
Kamei, H1
Okabe, K1
Toki, H1

Reviews

4 reviews available for metoclopramide and Anorexia

ArticleYear
Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation.
    Journal of palliative care, 2002,Summer, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anorexia; Antiemetics; Delayed-Action Preparat

2002
Treatment of the cancer anorexia-cachexia syndrome: a critical reappraisal.
    Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:3

    Topics: Anorexia; Cachexia; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Medro

2003
Systematic review of the treatment of cancer-associated anorexia and weight loss.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Nov-20, Volume: 23, Issue:33

    Topics: Adrenal Cortex Hormones; Adult; Anorexia; Antiemetics; Appetite Stimulants; Humans; Metoclopramide;

2005
Management of anorexia-cachexia associated with cancer and HIV infection.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:9 Suppl

    Topics: Anorexia; Antineoplastic Agents; Cachexia; Dronabinol; HIV Infections; Humans; Hydrazines; Megestrol

1991

Trials

6 trials available for metoclopramide and Anorexia

ArticleYear
Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation.
    Journal of palliative care, 2002,Summer, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anorexia; Antiemetics; Delayed-Action Preparat

2002
[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adult; Aged; Anorexia; Cisplatin; Domperidone; Drug Therapy, Combination; Female; Granisetron; Human

1993
Metoclopramide in anorexia caused by cancer-associated dyspepsia syndrome (CADS).
    Journal of palliative care, 1993,Summer, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anorexia; Dyspepsia; Female; Gastrointestinal

1993
[An early phase II trial combining cisplatin and carboplatin in advanced non-small cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:4

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-S

1993
[Randomized controlled study of high-dose metoclopramide and dexamethasone in the prevention of CDDP-induced emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:5

    Topics: Adult; Aged; Anorexia; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Dexamethasone; Dr

1986
[Antiemetic effects of combinations of metoclopramide, droperidol and dexamethasone for the prevention of cisplatin-induced gastro-intestinal toxicity: a randomized crossover trial].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:7

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as

1987

Other Studies

4 other studies available for metoclopramide and Anorexia

ArticleYear
Evidence that the anorexia induced by lipopolysaccharide is mediated by the 5-HT2C receptor.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2

    Topics: Adrenergic beta-Antagonists; Aminopyridines; Animals; Anorexia; Dopamine Antagonists; Dose-Response

2003
Neuroleptic-like anorexia produced by an extra-cerebral DA antagonist.
    Brain research bulletin, 1983, Volume: 11, Issue:1

    Topics: Animals; Anorexia; Antipsychotic Agents; Brain; Domperidone; Drinking Behavior; Feeding and Eating D

1983
Suspected herbicide toxicosis in a dog.
    Journal of the American Veterinary Medical Association, 1996, Dec-15, Volume: 209, Issue:12

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Abdominal Pain; Animals; Anorexia; Antidotes; Antiemetics; Atax

1996
Metoclopramide-induced parkinsonism.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Anorexia; Gastritis; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M

1987