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metoclopramide and Anesthesia

metoclopramide has been researched along with Anesthesia in 25 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"This research aimed to evaluate the effect of metoclopramide and ranitidine in the prevention of gastroesophageal reflux episodes during anesthetic procedures."7.78Evaluation of metoclopramide and ranitidine on the prevention of gastroesophageal reflux episodes in anesthetized dogs. ( Bonfá, LP; Costa, PR; Favarato, ES; Favarato, LS; Monteiro, BS; Nehme, RC; Souza, MV, 2012)
" 5 min prior to morphine while each ferret was maintained under isoflurane-O2 anesthesia."7.68The effects of different antiemetic agents on morphine-induced emesis in ferrets. ( Essien, E; Thut, PD; Wynn, RL, 1993)
"Metoclopramide has been shown to inhibit PCHE in vitro."5.36Metoclopramide does not prolong duration of action of landiolol attenuating the hemodynamic response to induction of anesthesia and tracheal intubation. ( Abe, R; Furuya, H; Inoue, S; Kawaguchi, M; Kobayashi, H, 2010)
" Before induction of anesthesia, patients were randomly allocated to receive intravenously dexamethasone (8 mg) in group D, ondansetron (4 mg) in group O, metoclopramide (10 mg) in group M, and saline (2 mL) in group P."5.14A comparative study of the antiemetic efficacy of dexamethasone, ondansetron, and metoclopramide in patients undergoing gynecological surgery. ( Bilgin, TE; Birbicer, H; Doruk, N; Oral, U; Ozer, Z; Tok, E, 2010)
"Whether nitrous oxide (N(2)O) increases the incidence of postoperative nausea and vomiting (PONV) after laparoscopic gynecologic surgery is still controversial, which may be due to the administration of different concentrations of inspired N(2)O."5.13The dose-response of nitrous oxide in postoperative nausea in patients undergoing gynecologic laparoscopic surgery: a preliminary study. ( Gan, TJ; Mraovic, B; Simurina, T; Skitarelic, N; Sonicki, Z, 2008)
"This research aimed to evaluate the effect of metoclopramide and ranitidine in the prevention of gastroesophageal reflux episodes during anesthetic procedures."3.78Evaluation of metoclopramide and ranitidine on the prevention of gastroesophageal reflux episodes in anesthetized dogs. ( Bonfá, LP; Costa, PR; Favarato, ES; Favarato, LS; Monteiro, BS; Nehme, RC; Souza, MV, 2012)
" 5 min prior to morphine while each ferret was maintained under isoflurane-O2 anesthesia."3.68The effects of different antiemetic agents on morphine-induced emesis in ferrets. ( Essien, E; Thut, PD; Wynn, RL, 1993)
"Metoclopramide has been shown to inhibit PCHE in vitro."1.36Metoclopramide does not prolong duration of action of landiolol attenuating the hemodynamic response to induction of anesthesia and tracheal intubation. ( Abe, R; Furuya, H; Inoue, S; Kawaguchi, M; Kobayashi, H, 2010)
"Metoclopramide (MCP) is a potent antiemetic, effective even for preventing emesis induced by cancer chemotherapy."1.33Rapid-onset intranasal delivery of metoclopramide hydrochloride. Part I. Influence of formulation variables on drug absorption in anesthetized rats. ( Abd ElHady, SS; Awad, GA; Mortada, ND; Zaki, NM, 2006)
"Recent data describe the acid aspiration syndrome (AAS) as the cause of 25% of maternal deaths associated with anaesthesia and 19% of all deaths totally attributable to anaesthesia (DHSS, 1982; Lunn and Mushin, 1982)."1.27Aspiration of gastric contents. ( Nimmo, WS, 1985)
"Pretreatment with metoclopramide (5 mg/kg i."1.27Mechanism of the pressor action of LY171555, a specific dopamine D2 receptor agonist, in the conscious rat. ( Chen, YF; Lindheimer, MD; Nagahama, S; Oparil, S, 1986)
"Metoclopramide pretreatment in urethane-anesthetized rats prevented the decreases in MAP and heart rate induced by LY171555, whereas pretreatment with d(CH2)5Tyr(Me)AVP delayed the recovery phase of the depressor response."1.27Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat. ( Chen, YF; Lindheimer, MD; Nagahama, S; Oparil, S, 1986)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199013 (52.00)18.7374
1990's3 (12.00)18.2507
2000's4 (16.00)29.6817
2010's4 (16.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Barney, EZ1
Fuller, ME1
Habib, AS1
Duque, M1
Santos, L1
Ribeiro, S1
Catré, D1
Mraovic, B1
Simurina, T1
Sonicki, Z1
Skitarelic, N1
Gan, TJ1
Kolodzie, K1
Apfel, CC1
Inoue, S1
Abe, R1
Kawaguchi, M1
Kobayashi, H1
Furuya, H1
Bilgin, TE1
Birbicer, H1
Ozer, Z1
Doruk, N1
Tok, E1
Oral, U1
Favarato, ES1
Souza, MV1
Costa, PR1
Favarato, LS1
Nehme, RC1
Monteiro, BS1
Bonfá, LP1
Imarengiaye, CO1
Ekwere, IT1
Zaki, NM1
Awad, GA1
Mortada, ND1
Abd ElHady, SS1
Palazzo, MG1
Strunin, L1
Manchikanti, L2
Marrero, TC1
Roush, JR1
Cohen, SE1
Jasson, J1
Talafre, ML1
Chauvelot-Moachon, L1
Barrier, G1
Olsson, GL1
Hallén, B1
Wynn, RL1
Essien, E1
Thut, PD1
LaGorio, J1
Thompson, VA1
Sternberg, D1
Dorje, P1
Inaba, K1
Morimoto, Y1
Fukuda, T1
Setoguchi, M1
Ciresi, SA1
Nimmo, WS1
Nagahama, S2
Chen, YF2
Lindheimer, MD2
Oparil, S2
McCammon, RL1
Adelhøj, B1
Petring, OU1
Coignet, J1
Diamond, MJ1
Grow, JB1
Colliver, JA1
Hadley, CH1
Hohlbein, LJ1

Reviews

5 reviews available for metoclopramide and Anesthesia

ArticleYear
Nausea and vomiting after office-based anesthesia.
    Current opinion in anaesthesiology, 2009, Volume: 22, Issue:4

    Topics: Anesthesia; Antiemetics; Droperidol; Haloperidol; Humans; Incidence; Metoclopramide; Neurokinin-1 Re

2009
Anaesthesia and emesis. II: Prevention and management.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Anesthesia; Antiemetics; Butyrophenones; Domperidone; Histamine H1 Antagonists; Humans; Metocloprami

1984
Gastrointestinal pharmacology review and anesthetic application to the combat casualty.
    Military medicine, 1989, Volume: 154, Issue:11

    Topics: Anesthesia; Digestive System; Drug Combinations; Histamine H2 Antagonists; Humans; Metoclopramide; P

1989
Prophylaxis for aspiration pneumonitis.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2

    Topics: Anesthesia; Animals; Antacids; Cimetidine; Esophagus; Gastric Emptying; Gastric Juice; Gastrointesti

1986
[Indications for primperan in pediatrics].
    Annales de gastroenterologie et d'hepatologie, 1985, May-28, Volume: 21, Issue:2 Pt 2

    Topics: Anesthesia; Child, Preschool; Digestive System; Gastric Emptying; Gastroesophageal Reflux; Gastroint

1985

Trials

4 trials available for metoclopramide and Anesthesia

ArticleYear
The dose-response of nitrous oxide in postoperative nausea in patients undergoing gynecologic laparoscopic surgery: a preliminary study.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Adult; Aged; Anesthesia; Dose-Response Relationship, Drug; Female; Gynecologic Surgical Procedures;

2008
A comparative study of the antiemetic efficacy of dexamethasone, ondansetron, and metoclopramide in patients undergoing gynecological surgery.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:7

    Topics: Adult; Anesthesia; Antiemetics; Dexamethasone; Female; Gynecologic Surgical Procedures; Humans; Hyst

2010
Preanesthetic cimetidine and metoclopramide for acid aspiration prophylaxis in elective surgery.
    Anesthesiology, 1984, Volume: 61, Issue:1

    Topics: Adult; Anesthesia; Cimetidine; Clinical Trials as Topic; Gastric Acid; Gastric Juice; Humans; Inhala

1984
Pharmacological evacuation of the stomach with metoclopramide.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:5

    Topics: Anesthesia; Child; Child, Preschool; Female; Fractures, Bone; Gastric Acidity Determination; Gastric

1982

Other Studies

16 other studies available for metoclopramide and Anesthesia

ArticleYear
Comparison of metoclopramide and promethazine for the treatment of postoperative nausea and vomiting in the post-anesthesia care unit: A retrospective database analysis.
    Journal of clinical anesthesia, 2020, Volume: 60

    Topics: Anesthesia; Antiemetics; Double-Blind Method; Humans; Metoclopramide; Ondansetron; Postoperative Nau

2020
Anesthesia and Brugada syndrome: a 12-year case series.
    Journal of clinical anesthesia, 2017, Volume: 36

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Anesthetics; Anesthetics, Intravenous; Brugada Syndrome

2017
Metoclopramide does not prolong duration of action of landiolol attenuating the hemodynamic response to induction of anesthesia and tracheal intubation.
    Journal of anesthesia, 2010, Volume: 24, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Blood Pressure; Drug Interactions; Heart Rate;

2010
Evaluation of metoclopramide and ranitidine on the prevention of gastroesophageal reflux episodes in anesthetized dogs.
    Research in veterinary science, 2012, Volume: 93, Issue:1

    Topics: Anesthesia; Animals; Antiemetics; Dog Diseases; Dogs; Esophagoscopy; Female; Gastroesophageal Reflux

2012
Acid aspiration prophylaxis and caesarean delivery: time for another close look.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2005, Volume: 25, Issue:4

    Topics: Anesthesia; Antacids; Cesarean Section; Female; Humans; Metoclopramide; Pneumonia, Aspiration; Pregn

2005
Rapid-onset intranasal delivery of metoclopramide hydrochloride. Part I. Influence of formulation variables on drug absorption in anesthetized rats.
    International journal of pharmaceutics, 2006, Dec-11, Volume: 327, Issue:1-2

    Topics: Absorption; Administration, Intranasal; Anesthesia; Animals; Antiemetics; Benzalkonium Compounds; Ch

2006
Does metoclopramide decrease the volume of gastric contents in patients undergoing cesarean section?
    Anesthesiology, 1984, Volume: 61, Issue:5

    Topics: Adult; Anesthesia; Cesarean Section; Female; Gastric Acidity Determination; Gastrointestinal Content

1984
The effects of different antiemetic agents on morphine-induced emesis in ferrets.
    European journal of pharmacology, 1993, Sep-07, Volume: 241, Issue:1

    Topics: Anesthesia; Animals; Antiemetics; Droperidol; Ferrets; Granisetron; Injections, Intravenous; Isoflur

1993
Akathisia and anesthesia: refusal of surgery after the administration of metoclopramide.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Anesthesia; Dopamine Antagonists; Humans; Male; Metoclopramide; Trea

1998
[Inhibition by Y-25130 of the von Bezold-Jarisch effect evoked by 5-HT or 2-methyl-5-HT in anesthetized rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:4

    Topics: Anesthesia; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Heart Rate;

1991
Aspiration of gastric contents.
    British journal of hospital medicine, 1985, Volume: 34, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Anesthesia; Anesthesia, Obstetrical; Cimetidine; Citrates;

1985
Mechanism of the pressor action of LY171555, a specific dopamine D2 receptor agonist, in the conscious rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: Adrenal Medulla; Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Ergolines; Hexamethonium

1986
[Anesthesia and metoclopramide].
    Ugeskrift for laeger, 1986, Jul-28, Volume: 148, Issue:31

    Topics: Anesthesia; Humans; Intraoperative Complications; Metoclopramide; Postoperative Complications; Preme

1986
Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Domperidone; Drug Interactions; Epinephri

1986
Anaesthesia and emesis. Clinical usefulness of metoclopramide.
    Canadian Anaesthetists' Society journal, 1985, Volume: 32, Issue:2

    Topics: Adult; Anesthesia; Humans; Metoclopramide; Postoperative Complications; Vomiting

1985
Bicitra (sodium citrate) and metoclopramide in outpatient anesthesia for prophylaxis against aspiration pneumonitis.
    Anesthesiology, 1985, Volume: 63, Issue:4

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia; Antacids; Cimetidine; Citrates; Citric Acid; Fema

1985