metoclopramide has been researched along with Amyotrophic Lateral Sclerosis in 3 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Secretion of prolactin in nine patients with amyotrophic lateral sclerosis and in seven healthy men was investigated with the use of metoclopramide stimulation and bromocriptine inhibition tests." | 7.67 | Effect of bromocriptine and metoclopramide on serum prolactin levels in patients with amyotrophic lateral sclerosis. ( Cieślak, D; Klimek, A; Stepień, H; Szulc-Kuberska, J, 1988) |
| "Secretion of prolactin in nine patients with amyotrophic lateral sclerosis and in seven healthy men was investigated with the use of metoclopramide stimulation and bromocriptine inhibition tests." | 3.67 | Effect of bromocriptine and metoclopramide on serum prolactin levels in patients with amyotrophic lateral sclerosis. ( Cieślak, D; Klimek, A; Stepień, H; Szulc-Kuberska, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, G | 1 |
| Hrabe, J | 1 |
| Sanchez, R | 1 |
| Szulc-Kuberska, J | 2 |
| Stepień, H | 2 |
| Klimek, A | 2 |
| Cieślak, D | 2 |
3 other studies available for metoclopramide and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Colostomy as a definitive treatment in an ALS patient with acute colonic Pseudo-obstruction refractory to medical management, a case report.
Topics: Acute Disease; Adult; Amyotrophic Lateral Sclerosis; Colonic Pseudo-Obstruction; Colostomy; Dioctyl | 2022 |
Effect of bromocriptine and metoclopramide on serum prolactin levels in patients with amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Bromocriptine; Humans; Hypothalamo-Hypophyseal System; Metoclop | 1988 |
[Effect of metoclopramide on prolactin secretion in amyotrophic lateral sclerosis].
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Humans; Male; Metoclopramide; Middle Aged; Pitui | 1987 |