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metoclopramide and Air Sickness

metoclopramide has been researched along with Air Sickness in 15 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"This is an evaluation of the efficacy of metoclopramide (MTCP) or diphenhydramine (DPH) to relieve symptoms of motion sickness in patients being transported via ambulance in a mountainous setting."9.15Motion sickness: comparison of metoclopramide and diphenhydramine to placebo. ( Andrews, J; Rubio, S; Weichenthal, L, 2011)
"A prospective randomized study was performed to assess the value of some individual risk factors for postoperative nausea and vomiting (PONV), and to compare the efficacy of ondansetron, metoclopramide, dexamethason, and combinations of these antiemetics in preventing PONV in patients after laparoscopic cholecystectomy."9.12Ondansetron, metoclopramid, dexamethason, and their combinations compared for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: a prospective randomized study. ( Leksowski, K; Peryga, P; Szyca, R, 2006)
"Prophylactic therapy with granisetron is superior to droperidol or metoclopramide for the prevention of POV after tonsillectomy in children with a history of motion sickness."9.09Comparison of granisetron, droperidol, and metoclopramide for prevention of postoperative vomiting in children with a history of motion sickness undergoing tonsillectomy. ( Fujii, Y; Tanaka, H, 2001)
" This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model."9.08Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997)
"Granisetron is a better prophylactic antiemetic than droperidol or metoclopramide in female patients with a history of motion sickness undergoing major gynaecological surgery."9.08Prevention of PONV with granisetron, droperidol and metoclopramide in female patients with history of motion sickness. ( Fujii, Y; Tanaka, H; Toyooka, H, 1997)
"Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea."7.80Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014)
"Orally administered metoclopramide (REGLAN) at doses of 10 or 20 mg, 75 min prior to either stressful linear acceleration (parabolic flight) or cross-coupled accelerative semicircular canal stimulation in a rotating chair was evaluated for its ability to prevent emesis or nausea II, respectively."7.67Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration. ( Kohl, RL, 1987)
"Metoclopramide was orally administered (10 or 20 mg) to 22 subjects, 75 min before parabolic flight."5.27Hormonal responses of metoclopramide-treated subjects experiencing nausea or emesis during parabolic flight. ( Kohl, RL, 1987)
"This is an evaluation of the efficacy of metoclopramide (MTCP) or diphenhydramine (DPH) to relieve symptoms of motion sickness in patients being transported via ambulance in a mountainous setting."5.15Motion sickness: comparison of metoclopramide and diphenhydramine to placebo. ( Andrews, J; Rubio, S; Weichenthal, L, 2011)
"A prospective randomized study was performed to assess the value of some individual risk factors for postoperative nausea and vomiting (PONV), and to compare the efficacy of ondansetron, metoclopramide, dexamethason, and combinations of these antiemetics in preventing PONV in patients after laparoscopic cholecystectomy."5.12Ondansetron, metoclopramid, dexamethason, and their combinations compared for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: a prospective randomized study. ( Leksowski, K; Peryga, P; Szyca, R, 2006)
"Prophylactic therapy with granisetron is superior to droperidol or metoclopramide for the prevention of POV after tonsillectomy in children with a history of motion sickness."5.09Comparison of granisetron, droperidol, and metoclopramide for prevention of postoperative vomiting in children with a history of motion sickness undergoing tonsillectomy. ( Fujii, Y; Tanaka, H, 2001)
" This difference was still significant when controlling for age, body weight, history of motion sickness, previous PONV episodes, duration of anesthesia, and intraoperative fentanyl consumption using a logistic model."5.08Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997)
"Granisetron is a better prophylactic antiemetic than droperidol or metoclopramide in female patients with a history of motion sickness undergoing major gynaecological surgery."5.08Prevention of PONV with granisetron, droperidol and metoclopramide in female patients with history of motion sickness. ( Fujii, Y; Tanaka, H; Toyooka, H, 1997)
"Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea."3.80Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014)
"Orally administered metoclopramide (REGLAN) at doses of 10 or 20 mg, 75 min prior to either stressful linear acceleration (parabolic flight) or cross-coupled accelerative semicircular canal stimulation in a rotating chair was evaluated for its ability to prevent emesis or nausea II, respectively."3.67Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration. ( Kohl, RL, 1987)
"Metoclopramide was orally administered (10 or 20 mg) to 22 subjects, 75 min before parabolic flight."1.27Hormonal responses of metoclopramide-treated subjects experiencing nausea or emesis during parabolic flight. ( Kohl, RL, 1987)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's3 (20.00)18.2507
2000's2 (13.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dahl, E1
Diskin, AL1
Banting, J1
Meriano, T1
Rubio, S1
Weichenthal, L1
Andrews, J1
Leksowski, K1
Peryga, P1
Szyca, R1
Scherer, H1
Polati, E1
Verlato, G1
Finco, G1
Mosaner, W1
Grosso, S1
Gottin, L1
Pinaroli, AM1
Ischia, S1
Fujii, Y2
Toyooka, H1
Tanaka, H2
Gibbs, D1
Milton-Thompson, GJ1
Wood, CD1
Stewart, JJ1
Wood, MJ1
Manno, JE1
Manno, BR1
Mims, ME1
Kohl, RL2
McMurray, GN1

Reviews

2 reviews available for metoclopramide and Air Sickness

ArticleYear
Sea State Green.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2016,summer, Volume: 16, Issue:2

    Topics: Acupressure; Antiemetics; Cholinergic Antagonists; Dopamine Antagonists; Emergency Medical Technicia

2016
[Orientation in space, its disturbance by disease (vertigo) and exogenous kinetic processes (kinetoses) (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1982, Mar-19, Volume: 124, Issue:11

    Topics: Adult; Child; Humans; Kinesis; Metoclopramide; Motion Sickness; Orientation; Scopolamine; Vertigo

1982

Trials

7 trials available for metoclopramide and Air Sickness

ArticleYear
Motion sickness: comparison of metoclopramide and diphenhydramine to placebo.
    Prehospital and disaster medicine, 2011, Volume: 26, Issue:4

    Topics: Diphenhydramine; Double-Blind Method; Humans; Metoclopramide; Motion Sickness; Pain Measurement; Pro

2011
Ondansetron, metoclopramid, dexamethason, and their combinations compared for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: a prospective randomized study.
    Surgical endoscopy, 2006, Volume: 20, Issue:6

    Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Dexamethasone; Drug Therapy, Combination; F

2006
Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemet

1997
Prevention of PONV with granisetron, droperidol and metoclopramide in female patients with history of motion sickness.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:8

    Topics: Adult; Antiemetics; Double-Blind Method; Droperidol; Female; Granisetron; Humans; Metoclopramide; Mi

1997
Comparison of granisetron, droperidol, and metoclopramide for prevention of postoperative vomiting in children with a history of motion sickness undergoing tonsillectomy.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:3

    Topics: Analysis of Variance; Antiemetics; Child, Preschool; Double-Blind Method; Droperidol; Female; Granis

2001
Therapeutic effects of antimotion sickness medications on the secondary symptoms of motion sickness.
    Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Arousal; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; E

1990
An evaluation of metoclopramide as an anti-emetic in seasickness.
    Postgraduate medical journal, 1973, Volume: 49 Suppl 4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypnotics a

1973

Other Studies

6 other studies available for metoclopramide and Air Sickness

ArticleYear
Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting.
    International maritime health, 2014, Volume: 65, Issue:1

    Topics: Adult; Antiemetics; Diphenhydramine; Dyskinesias; Female; Gastroenteritis; Humans; Injections, Intra

2014
Drugs for travel sickness.
    Drug and therapeutics bulletin, 1981, Feb-27, Volume: 19, Issue:5

    Topics: Histamine H1 Antagonists; Humans; Metoclopramide; Motion Sickness; Parasympatholytics

1981
Diseases of the alimentary system; Nausea and vomiting.
    British medical journal, 1976, Dec-18, Volume: 2, Issue:6050

    Topics: Antiemetics; Female; Histamine H1 Antagonists; Humans; Metoclopramide; Motion Sickness; Nausea; Phen

1976
Anti-nauseant drugs.
    The Practitioner, 1979, Volume: 223, Issue:1336

    Topics: Antiemetics; Antipsychotic Agents; Female; Gastrointestinal Diseases; Histamine H1 Antagonists; Huma

1979
Hormonal responses of metoclopramide-treated subjects experiencing nausea or emesis during parabolic flight.
    Aviation, space, and environmental medicine, 1987, Volume: 58, Issue:9 Pt 2

    Topics: Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Epinephrine; Humans; Metoclopramide; Motio

1987
Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration.
    Aviation, space, and environmental medicine, 1987, Volume: 58, Issue:2

    Topics: Acceleration; Adult; Coriolis Force; Humans; Metoclopramide; Motion Sickness; Nausea; Space Flight

1987