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metoclopramide and Agitation, Psychomotor

metoclopramide has been researched along with Agitation, Psychomotor in 8 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy and frequency of akathisia and dystonia between the dopamine antagonist headache medications olanzapine, metoclopramide and prochlorperazine."8.31Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023)
"We considered akathisia and cancer-related anxiety/agitation as possible causes of restlessness and insomnia, and prescribed clonazepam."5.72Prolonged extrapyramidal symptoms induced by long-term, intermittent administration of low-dose olanzapine along with metoclopramide for emesis: A case report. ( Deguchi, Y; Inoue, K; Itoh, Y; Sakamoto, S; Uchida, S, 2022)
"This review found insufficient evidence to recommend the use of diphenhydramine as an adjunct therapy to prevent akathisia in ED patients treated with neuroleptics or metoclopramide for primary headache."5.41Adjuvant anticholinergic therapy for the prevention of akathisia in patients with primary headache in the emergency department: A systematic review. ( Campbell, S; Kirkland, SW; Meyer, J; Rowe, BH; Villa-Roel, C, 2023)
"To compare the efficacy and frequency of akathisia and dystonia between the dopamine antagonist headache medications olanzapine, metoclopramide and prochlorperazine."4.31Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023)
"The main outcome was development of akathisia noted at 60 minutes after drug administration as measured either with The Prince Henry Hospital akathisia rating scale or by sudden unexplained departure from the ED during treatment."2.74Slower infusion of metoclopramide decreases the rate of akathisia. ( Hoffman, RS; Nelson, LS; Regan, LA, 2009)
"We considered akathisia and cancer-related anxiety/agitation as possible causes of restlessness and insomnia, and prescribed clonazepam."1.72Prolonged extrapyramidal symptoms induced by long-term, intermittent administration of low-dose olanzapine along with metoclopramide for emesis: A case report. ( Deguchi, Y; Inoue, K; Itoh, Y; Sakamoto, S; Uchida, S, 2022)
"As metoclopramide is a dopamine receptor antagonist, it has the potential to cause drug-induced movement disorders, including akathisia, which is characterised by an inner restlessness resulting in a need for constant movement."1.62[Tardive akathisia after long-term metoclopramide treatment]. ( Andersen, CU; Hjelholt, AJ; Steffensen, C, 2021)
" Extrapyramidal side effects like tardive dyskinesia are known to develop with chronic use of metoclopramide, while acute akathisia is a lesser known side effect following IV administration."1.37Case of acute akathisia from intravenous metoclopramide. ( Lim, BL; Qiu, LM, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Sakamoto, S1
Deguchi, Y1
Uchida, S1
Itoh, Y1
Inoue, K1
Meyer, J1
Kirkland, SW1
Campbell, S1
Villa-Roel, C1
Rowe, BH1
Chinn, E1
Brunette, ND1
Driver, BE1
Klein, LR1
Stang, JL1
DeVries, P1
Mojica, E1
Raiter, A1
Miner, JR1
Cole, JB1
Hjelholt, AJ1
Andersen, CU1
Steffensen, C1
Regan, LA1
Hoffman, RS1
Nelson, LS1
Qiu, LM1
Lim, BL1
Rodgers, C1
Sachdev, P1
Chee, KY1

Reviews

1 review available for metoclopramide and Agitation, Psychomotor

ArticleYear
Adjuvant anticholinergic therapy for the prevention of akathisia in patients with primary headache in the emergency department: A systematic review.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2023, Volume: 30, Issue:1

    Topics: Adult; Antipsychotic Agents; Cholinergic Antagonists; Diphenhydramine; Emergency Service, Hospital;

2023

Trials

2 trials available for metoclopramide and Agitation, Psychomotor

ArticleYear
Slower infusion of metoclopramide decreases the rate of akathisia.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:4

    Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Metoclopramid

2009
Pharmacological characterization of tardive akathisia.
    Biological psychiatry, 1990, Nov-01, Volume: 28, Issue:9

    Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztr

1990

Other Studies

5 other studies available for metoclopramide and Agitation, Psychomotor

ArticleYear
Prolonged extrapyramidal symptoms induced by long-term, intermittent administration of low-dose olanzapine along with metoclopramide for emesis: A case report.
    Neuropsychopharmacology reports, 2022, Volume: 42, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Antipsychotic Agents; Biperiden; Clonazepam; Dopamine; Humans; M

2022
Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients.
    The American journal of emergency medicine, 2023, Volume: 65

    Topics: Cohort Studies; Double-Blind Method; Dystonia; Emergency Service, Hospital; Headache; Humans; Metocl

2023
[Tardive akathisia after long-term metoclopramide treatment].
    Ugeskrift for laeger, 2021, 05-24, Volume: 183, Issue:21

    Topics: Akathisia, Drug-Induced; Dopamine Antagonists; Drug-Related Side Effects and Adverse Reactions; Huma

2021
Case of acute akathisia from intravenous metoclopramide.
    Singapore medical journal, 2011, Volume: 52, Issue:1

    Topics: Abdominal Pain; Adult; Akathisia, Drug-Induced; Diphenhydramine; Emergency Service, Hospital; Female

2011
Extrapyramidal side effects of antiemetics presenting as psychiatric illness.
    General hospital psychiatry, 1992, Volume: 14, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Anxiety Disor

1992