metoclopramide has been researched along with Aging in 13 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pain on injection is still a major problem with propofol; metoclopramide effectively decreases this pain." | 9.12 | Age-related differences in metoclopramide requirement for pain on injection of propofol. ( Fujii, Y; Shiga, Y, 2006) |
| "Aging is known to reduce arginine vasopressin (AVP) response to volumetric stimulations and to increase AVP responses to osmotic stimuli and to administration of metoclopramide (MCP)." | 7.68 | Abnormal arginine vasopressin response to cigarette smoking and metoclopramide (but not to insulin-induced hypoglycemia) in elderly subjects. ( Bianconi, L; Caiazza, A; Capretti, L; Cavazzini, U; Chiodera, P; Coiro, V; Marchesi, C; Marchesi, M; Volpi, R, 1991) |
| "Pain on injection is still a major problem with propofol; metoclopramide effectively decreases this pain." | 5.12 | Age-related differences in metoclopramide requirement for pain on injection of propofol. ( Fujii, Y; Shiga, Y, 2006) |
| "To investigate the influence of aging on dopaminergic modulation of pulsatile thyrotropin (TSH) secretion, we examined changes in circulating TSH levels during the day and night, with and without a dopamine antagonist metoclopramide, in healthy young (20-35 yr old) and old (69-83 yr old) subjects, with the use of cluster analysis." | 3.68 | Age-related alterations in pulsatile secretion of TSH: role of dopaminergic regulation. ( Elahi, D; Greenspan, SL; Klibanski, A; Rowe, JW, 1991) |
| "Aging is known to reduce arginine vasopressin (AVP) response to volumetric stimulations and to increase AVP responses to osmotic stimuli and to administration of metoclopramide (MCP)." | 3.68 | Abnormal arginine vasopressin response to cigarette smoking and metoclopramide (but not to insulin-induced hypoglycemia) in elderly subjects. ( Bianconi, L; Caiazza, A; Capretti, L; Cavazzini, U; Chiodera, P; Coiro, V; Marchesi, C; Marchesi, M; Volpi, R, 1991) |
| " Blood and urine were collected for measurement of pharmacokinetic parameters." | 2.67 | The association of age and frailty with the pharmacokinetics and pharmacodynamics of metoclopramide. ( Bateman, DN; Boddy, A; Cope, LH; Woodhouse, KW; Wynne, HA; Yelland, C, 1993) |
| "Out-of-hospital sudden cardiac death was assessed by linkage with Hospital Episode Statistics and death certificates." | 1.42 | Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study. ( Arana, A; Fife, D; Johannes, CB; McQuay, LJ; Rothman, KJ; Varas-Lorenzo, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arana, A | 1 |
| Johannes, CB | 1 |
| McQuay, LJ | 1 |
| Varas-Lorenzo, C | 1 |
| Fife, D | 1 |
| Rothman, KJ | 1 |
| Madan, R | 1 |
| Bhatia, A | 1 |
| Chakithandy, S | 1 |
| Subramaniam, R | 1 |
| Rammohan, G | 1 |
| Deshpande, S | 1 |
| Singh, M | 1 |
| Kaul, HL | 1 |
| Fujii, Y | 1 |
| Shiga, Y | 1 |
| Van Arsdalen, KN | 1 |
| Wein, AJ | 1 |
| Scanlon, MF | 1 |
| Chan, V | 1 |
| Heath, M | 1 |
| Pourmand, M | 1 |
| Rodriguez-Arnao, MD | 1 |
| Weightman, DR | 1 |
| Lewis, M | 1 |
| Hall, R | 1 |
| Wynne, HA | 1 |
| Yelland, C | 1 |
| Cope, LH | 1 |
| Boddy, A | 1 |
| Woodhouse, KW | 1 |
| Bateman, DN | 1 |
| Ramírez, A | 2 |
| Espinosa de los Monteros, A | 2 |
| Coria, I | 1 |
| Hortencia Valencia, Q | 1 |
| Parra, A | 2 |
| Alarcón, J | 1 |
| Gaviño, F | 1 |
| Greenspan, SL | 2 |
| Klibanski, A | 2 |
| Rowe, JW | 2 |
| Elahi, D | 2 |
| Chiodera, P | 1 |
| Capretti, L | 1 |
| Marchesi, M | 1 |
| Caiazza, A | 1 |
| Bianconi, L | 1 |
| Cavazzini, U | 1 |
| Marchesi, C | 1 |
| Volpi, R | 1 |
| Coiro, V | 1 |
| Holt, PR | 1 |
| Mori, M | 1 |
| Hoshino, Y | 1 |
| Obara, H | 1 |
| Iwai, S | 1 |
3 trials available for metoclopramide and Aging
| Article | Year |
|---|---|
Prophylactic dexamethasone for postoperative nausea and vomiting in pediatric strabismus surgery: a dose ranging and safety evaluation study.
Topics: Adolescent; Aging; Anesthesia, General; Antiemetics; Blood Glucose; Child; Child, Preschool; Dexamet | 2005 |
Age-related differences in metoclopramide requirement for pain on injection of propofol.
Topics: Adult; Aged; Aging; Double-Blind Method; Female; Humans; Injections; Male; Metoclopramide; Middle Ag | 2006 |
The association of age and frailty with the pharmacokinetics and pharmacodynamics of metoclopramide.
Topics: Administration, Oral; Adult; Aged; Aging; Female; Frail Elderly; Humans; Infusions, Intravenous; Mal | 1993 |
10 other studies available for metoclopramide and Aging
| Article | Year |
|---|---|
Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study.
Topics: Aging; Antiemetics; Case-Control Studies; Death, Sudden, Cardiac; Domperidone; Dose-Response Relatio | 2015 |
Drug-induced sexual dysfunction in older men.
Topics: Aged; Aging; Antihypertensive Agents; Cimetidine; Clofibrate; Estrogens; Female; Humans; Male; Metoc | 1984 |
Dopaminergic control of thyrotropin, alpha-subunit, thyrotropin beta-subunit, and prolactin in euthyroidism and hypothyroidism: dissociated responses to dopamine receptor blockade with metoclopramide in hypothyroid subjects.
Topics: Adult; Aged; Aging; Dopamine; Female; Humans; Hypothyroidism; Kinetics; Male; Metoclopramide; Middle | 1981 |
[Serum prolactin during oral metoclopramide in normal nulliparous women].
Topics: Administration, Oral; Adolescent; Adult; Aging; Analysis of Variance; Female; Humans; Menstrual Cycl | 1993 |
Age-related changes in the metoclopramide-induced prolactin release in nulliparous women.
Topics: Administration, Oral; Adolescent; Adult; Aging; Female; Humans; Metoclopramide; Middle Aged; Parity; | 1993 |
Age-related alterations in pulsatile secretion of TSH: role of dopaminergic regulation.
Topics: Adult; Aged; Aging; Circadian Rhythm; Cluster Analysis; Dopamine; Humans; Kinetics; Male; Metoclopra | 1991 |
Abnormal arginine vasopressin response to cigarette smoking and metoclopramide (but not to insulin-induced hypoglycemia) in elderly subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine Vasopressin; Blood Glucose; Humans; Hydrocortisone; | 1991 |
Age alters pulsatile prolactin release: influence of dopaminergic inhibition.
Topics: Adult; Aged; Aging; Circadian Rhythm; Humans; Male; Metoclopramide; Prolactin; Reference Values | 1990 |
Gastrointestinal drugs in the elderly.
Topics: Aged; Aging; Aluminum; Antacids; Antidiarrheals; Biological Availability; Digestive System; Drug Int | 1986 |
Maturation-related changes in dopamine-induced relaxation of isolated rabbit pulmonary artery.
Topics: Aging; Animals; Dopamine; Dose-Response Relationship, Drug; Female; Flupenthixol; Male; Metocloprami | 1988 |