metoclopramide and Acute Disease studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

Excerpt	Relevance	Reference
"When intravenous morphine is administered for acute pain, the overall incidence of nausea and vomiting is low, regardless of whether these patients are given prophylactic metoclopramide or not."	9.12	Use of a prophylactic antiemetic with morphine in acute pain: randomised controlled trial. ( Bradshaw, M; Sen, A, 2006)
"The aim of our single-center, prospective, randomized, open study was to evaluate the antiemetic efficacy and tolerability of a regimen based on a single oral dose of ondansetron 8 mg in comparison with a metoclopramide-based regimen, for prevention of acute FAC (fluorouracil, doxorubicin and cyclophosphamide) chemotherapy-induced emesis."	9.09	High efficacy of a single oral dose of ondansetron 8 mg versus a metoclopramide regimen in the prevention of acute emesis induced by fluorouracil, doxorubicin and cyclophosphamide (FAC) chemotherapy for breast cancer. ( Bosnjak, SM; Mitrovi, LB; Nesković-Konstantinović, ZB; Radulović, SS; Susnjar, S, 2000)
"Several studies have confirmed the efficacy of high-dose metoclopramide and, more recently, serotonin antagonists, with and without dexamethasone, in the prophylaxis of cisplatin-induced nausea and vomiting."	9.09	Prospective randomized comparison of tropisetron with and without dexamethasone against high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. ( Hussain, M; Khan, Z; Malik, I; Moid, I, 1999)
"Ondansetron, a 5HT3 receptor antagonist, was significantly superior to placebo in preventing emesis associated with acute gastroenteritis, in paediatric patients."	9.08	Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997)
"The potent serotonin receptor (5-HT3) antagonists are new highly selective agents for the prevention and control of chemotherapy-induced nausea and vomiting that have been shown to be comparable to or more effective than traditional metoclopramide regimens."	9.08	A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy. ( Bastit, P; Cals, L; Cappelaere, P; Catimel, G; Chevallier, B; Claverie, N; Fabbro, M; Giovannini, M; Khayat, D; Splinter, T; Wendling, JL, 1997)
"Metoclopramide is an active antiemetic against cisplatin-induced acute emesis."	9.07	Continuous infusion versus intermittent short infusion of metoclopramide for cisplatin-induced acute emesis. ( Kajita, M; Niimi, T; Saito, H; Shimokata, K; Yamori, S, 1994)
"Tropisetron+dexamethasone was significantly superior to tropisetron alone both for acute (P = 0."	6.68	Comparison of three tropisetron-containing antiemetic regimens in the prophylaxis of acute and delayed chemotherapy-induced emesis and nausea. ( Bangerter, M; Bruntsch, U; Drechsler, S; Eggert, J; Faerber, L; Gallmeier, WM; Gosse, H; Grote-Kiehn, J; Imhoff, W; Mezger, J; Oehm, C; Ukena, D; Untch, M, 1997)
"Tropisetron is an effective and well-tolerated agent in the prevention of chemotherapy-induced vomiting."	6.67	Tropisetron compared with a metoclopramide-based regimen in the prevention of chemotherapy-induced nausea and vomiting. ( Anderson, H; de Bruijn, KM; Howell, A; Logan, K; Sage, T; Thatcher, N, 1994)
"A patient developed acute dystonia following intravenous administration of metocroplamide 20 mg."	5.42	[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol]. ( Iwade, M; Kamata, K; Morioka, N; Nakashima, K; Ozaki, M; Takahashi, E, 2015)
"Patients presenting with moderate to severe intensity migraine without aura were randomized to receive either 400 mg of iVPA or 10 mg intramuscular metoclopramide + 6 mg SQ sumatriptan (30 patients in each study arm)."	5.17	A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache. ( Bakhshayesh, B; Hatamian, H; Hossieninezhad, M; Rezania, K; Seyed Saadat, SM, 2013)
"When intravenous morphine is administered for acute pain, the overall incidence of nausea and vomiting is low, regardless of whether these patients are given prophylactic metoclopramide or not."	5.12	Use of a prophylactic antiemetic with morphine in acute pain: randomised controlled trial. ( Bradshaw, M; Sen, A, 2006)
"Several studies have confirmed the efficacy of high-dose metoclopramide and, more recently, serotonin antagonists, with and without dexamethasone, in the prophylaxis of cisplatin-induced nausea and vomiting."	5.09	Prospective randomized comparison of tropisetron with and without dexamethasone against high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. ( Hussain, M; Khan, Z; Malik, I; Moid, I, 1999)
"The aim of our single-center, prospective, randomized, open study was to evaluate the antiemetic efficacy and tolerability of a regimen based on a single oral dose of ondansetron 8 mg in comparison with a metoclopramide-based regimen, for prevention of acute FAC (fluorouracil, doxorubicin and cyclophosphamide) chemotherapy-induced emesis."	5.09	High efficacy of a single oral dose of ondansetron 8 mg versus a metoclopramide regimen in the prevention of acute emesis induced by fluorouracil, doxorubicin and cyclophosphamide (FAC) chemotherapy for breast cancer. ( Bosnjak, SM; Mitrovi, LB; Nesković-Konstantinović, ZB; Radulović, SS; Susnjar, S, 2000)
"Ondansetron, a 5HT3 receptor antagonist, was significantly superior to placebo in preventing emesis associated with acute gastroenteritis, in paediatric patients."	5.08	Antiemetic activity of ondansetron in acute gastroenteritis. ( Cubeddu, LX; Gonzalez, V; Guariguata, J; Miller, IA; Paska, W; Seijas, J; Talmaciu, I; Trujillo, LM, 1997)
"The potent serotonin receptor (5-HT3) antagonists are new highly selective agents for the prevention and control of chemotherapy-induced nausea and vomiting that have been shown to be comparable to or more effective than traditional metoclopramide regimens."	5.08	A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy. ( Bastit, P; Cals, L; Cappelaere, P; Catimel, G; Chevallier, B; Claverie, N; Fabbro, M; Giovannini, M; Khayat, D; Splinter, T; Wendling, JL, 1997)
"Metoclopramide is an active antiemetic against cisplatin-induced acute emesis."	5.07	Continuous infusion versus intermittent short infusion of metoclopramide for cisplatin-induced acute emesis. ( Kajita, M; Niimi, T; Saito, H; Shimokata, K; Yamori, S, 1994)
"Ondansetron plus dexamethasone was significantly more efficacious and better tolerated than metoclopramide plus dexamethasone and diphenhydramine during three cycles of chemotherapy and, in contrast to the metoclopramide regimen, the efficacy of ondansetron plus dexamethasone, at least for vomiting, is maintained in subsequent cycles."	5.07	Difference in persistence of efficacy of two antiemetic regimens on acute emesis during cisplatin chemotherapy. The Italian Group for Antiemetic Research. ( , 1993)
" dexamethasone and oral metoclopramide) for delayed emesis, while they had received either i."	5.07	Cisplatin-induced delayed emesis: pattern and prognostic factors during three subsequent cycles. Italian Group for Antiemetic Research. ( , 1994)
" Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0."	5.05	Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020)
"Oral ondansetron increased the proportion of patients who had ceased vomiting and reduced the number needing intravenous rehydration and immediate hospital admission."	4.87	Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Carter, B; Fedorowicz, Z; Jagannath, VA, 2011)
"The objective of the present study was to conduct a systematic review and meta-analysis of randomized controlled trials, comparing metoclopramide with placebo, for preventing vomiting in patients who have received i."	4.87	Review article: Prophylactic metoclopramide for patients receiving intravenous morphine in the emergency setting: a systematic review and meta-analysis of randomized controlled trials. ( Bendall, JC; Middleton, PM; Simpson, PM, 2011)
"The small number of included trials provided some limited evidence favouring the use of ondansetron and metoclopramide over placebo to reduce the number of episodes of vomiting due to gastroenteritis in children."	4.85	Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Al-Hashimi, H; Alhashimi, D; Fedorowicz, Z, 2009)
"The small number of included trials provided some, albeit weak and unreliable, evidence which appeared to favor the use of ondansetron and metoclopramide over placebo to reduce the number of episodes of vomiting due to gastroenteritis in children."	4.83	Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Alhashimi, D; Alhashimi, H; Fedorowicz, Z, 2006)
" Although no data were available for the precise time to cessation of vomiting (the primary outcome specified in the protocol for this review), one trial reported that the proportion of patients without vomiting over a 24 hour period was higher in the ondansetron and metoclopramide groups than placebo."	4.83	Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. ( Alhashimi, D; Alhashimi, H; Fedorowicz, Z, 2006)
"We report a case of acute dystonia of the face, jaw and tongue caused by metoclopramide and mimicking angioedema."	3.79	Acute dystonia mimicking angioedema of the tongue: a video-illustrated case. ( Bygum, A; Pallesen, KA; Rasmussen, ER, 2013)
" We present a case of acute dystonia with upper limbs tremors after medication with metoclopramide and neuroleptic drugs in young patient operated on acute aortic dissection."	3.77	Diagnostic difficulties of neurological complications after surgical treatment of acute ascending aorta dissection - a case report. ( Kozłowicz, M; Krawczyk, E; Olszewski, K; Stążka, J, 2011)
"Two girls, aged 2 and 4 years, with acute gastroenteritis and vomiting, received domperidone and metoclopramide, respectively."	3.73	[Urinary retention in 2 children after the use of antiemetic agents during acute gastroenteritis]. ( de Moor, RA; Diemont, WL; van den Bemt, PM; Visser, MO, 2005)
"Extrapyramidal syndromes (EPS) are clinically relevant side effects of metoclopramide which are often not anticipated."	3.73	Acute dystonic reaction to metoclopramide in patients carrying homozygous cytochrome P450 2D6 genetic polymorphisms. ( Sonneveld, P; van der Padt, A; van Schaik, RH, 2006)
" Intravenous ondansetron 8 mg and dexamethasone 20 mg served as an alternative regimen in patients <30 years old with a history of extrapyramidal manifestations or emesis in previous cycles."	3.70	Anthropometric and pharmacotherapeutic variables on acute emesis induced by cisplatin-containing chemotherapy. ( Catalán Arlandis, JL; Jiménez Torres, NV, 2000)
"Lorazepam, dexamethasone and high-dose metoclopramide were given to 54 patients to prevent emesis induced by cisplatin (50-120 mg/m2) on day 1, while prochlorperazine and dexamethasone were administered on days 2 and 3 for control of delayed emesis."	3.68	Acute and delayed emesis after cisplatin-based regimen: description and prevention. ( Beaulieu, R; Courchesne, Y; Latreille, J; Letendre, F; Lorange, A; Louvet, C; Monte, M; Neemeh, JA; Pretty, HM, 1991)
"A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide."	3.67	Acute intermittent porphyria in pregnancy. ( Arlazoroff, A; Caspi, E; Klein, C; Milo, R; Neuman, M, 1989)
"Patients with migraine of moderate or severe intensity were randomized to receive bilateral GONB with each side administered 3 mL of bupivacaine 0."	2.94	A Randomized, Double-Dummy, Emergency Department-Based Study of Greater Occipital Nerve Block With Bupivacaine vs Intravenous Metoclopramide for Treatment of Migraine. ( Bijur, PE; Del Valle, M; Friedman, BW; Gallagher, EJ; Harrilal, MA; Irizarry, E; Robbins, MS; Solorzano, C; Williams, A; Zias, E, 2020)
"Included patients met the migraine criteria of the International Headache Society."	2.84	Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial. ( Akalın, LE; Alyeşil, C; Avcu, N; Doğan, NÖ; Pekdemir, M; Yaka, E; Yılmaz, S, 2017)
"Haloperidol has been shown to be effective for migraine treatment."	2.80	A Randomized Controlled Trial of Intravenous Haloperidol vs. Intravenous Metoclopramide for Acute Migraine Therapy in the Emergency Department. ( Bruner, DI; Frumkin, K; Gaffigan, ME; Pritchard, A; Wason, C, 2015)
"Migraine is one of the commonest diseases of clinical practice."	2.72	[Comparison of intravenous dipyrone to intravenous metoclopramide in the treatment of acute crisis of migraine: randomized clinical trial]. ( Costa, MS; Fernandes Filho, SM; Fernandes, MT; Foerster, MV, 2006)
"Heptaplatin is a newly developed platinum derivative which has been reported to be less toxic than cisplatin."	2.70	Nephrotoxicity of heptaplatin: a randomized comparison with cisplatin in advanced gastric cancer. ( Ahn, JH; Bahng, H; Chang, HM; Kang, WC; Kang, YK; Kim, TW; Kim, WK; Lee, JS; Park, JS, 2002)
"Both treatments reduced migraine-associated nausea, vomiting, phonophobia and photophobia."	2.70	Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study. ( Compagnon, A; Geraud, G; Rossi, A, 2002)
"Tropisetron+dexamethasone was significantly superior to tropisetron alone both for acute (P = 0."	2.68	Comparison of three tropisetron-containing antiemetic regimens in the prophylaxis of acute and delayed chemotherapy-induced emesis and nausea. ( Bangerter, M; Bruntsch, U; Drechsler, S; Eggert, J; Faerber, L; Gallmeier, WM; Gosse, H; Grote-Kiehn, J; Imhoff, W; Mezger, J; Oehm, C; Ukena, D; Untch, M, 1997)
"Tropisetron is an effective and well-tolerated agent in the prevention of chemotherapy-induced vomiting."	2.67	Tropisetron compared with a metoclopramide-based regimen in the prevention of chemotherapy-induced nausea and vomiting. ( Anderson, H; de Bruijn, KM; Howell, A; Logan, K; Sage, T; Thatcher, N, 1994)
"Thus metoclopramide seems to be an alternative to the traditional treatment of ureteral colic with morphia."	2.67	Metoclopramide (Primperan) in the treatment of ureterolithiasis. A prospective double-blind study of metoclopramide compared with morphatropin on ureteral colic. ( Glyngdal, P; Jensen, A; Müller, TF; Naesh, O; Svare, E, 1990)
"Treatments provided to improve dysphagia are aimed at accelerating recovery of swallowing function and reducing these risks."	2.58	Swallowing therapy for dysphagia in acute and subacute stroke. ( Bath, PM; Everton, LF; Lee, HS, 2018)
"Migraine is a common, disabling condition and a burden for the individual, health services and society."	2.49	Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. ( Derry, S; Moore, RA, 2013)
"Many therapies may not only relieve head pain, but also alleviate associated symptoms."	2.40	Management of an acute primary headache. ( Ward, TN, 1998)
"Acute vertigo is a common problem in emergency departments."	1.51	Comparison of acute vertigo diagnosis and treatment practices between otolaryngologists and non-otolaryngologists: A multicenter scenario-based survey. ( Azuma, H; Hiraoka, E; Kobayashi, D; Numata, K; Omura, K; Shiga, T; Umibe, A; Yamada, Y; Yamanaka, S, 2019)
"Restless legs syndrome is a chronic disorder that is characterized by an urge to move the legs and unpleasant sensations in the lower extremities."	1.51	Acute Drug-Induced Symptoms of Restless Legs Syndrome in an Emergency Department. ( Sieminski, M; Zemojtel, L, 2019)
"A patient developed acute dystonia following intravenous administration of metocroplamide 20 mg."	1.42	[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol]. ( Iwade, M; Kamata, K; Morioka, N; Nakashima, K; Ozaki, M; Takahashi, E, 2015)
"For moderate dehydration, eight CPGs advocated nasogastric (NG) rehydration in preference to intravenous (IV) rehydration."	1.35	Emergency department management of gastro-enteritis in Australia and New Zealand. ( Babl, FE; Borland, M; Schutz, J; Sheriff, N, 2008)
"Hypoxemia is known to induce various physiological changes which can result in alteration in drug pharmacokinetics."	1.31	Effects of acute moderate hypoxemia on kinetics of metoclopramide and its metabolites in chronically instrumented sheep. ( Kim, J; Riggs, KW; Rurak, DW, 2002)
"Metoclopramide is an antiemetic drug used frequently both in general practice and hospitals."	1.31	[Acute dystonia caused by metoclopramide (Afipran) therapy]. ( Bindoff, L; Farbu, E; Hagen, EM, 2001)
"Metoclopramide is an effective non-phenothiazine antiemetic that acts, in part, by blockade of the dopamine receptors."	1.27	Prolonged metoclopramide-induced dyskinetic reaction. ( Leopold, NA, 1984)
"Metoclopramide is a drug that increases gastrointestinal motility, has few significant side effects, and may be of use in decreasing the ileus associated with acute spinal cord injuries."	1.26	Prolonged ileus with acute spinal cord injury responding to metaclopramide. ( Fenzl, TC; Miller, F, 1981)
"In an acute migraine clinic, patients were all treated with metoclopramide 10 mg i."	1.26	Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine. ( Olesen, J; Tfelt-Hansen, P, 1980)
"A higher percentage of patients with migraine compared with those with tension headache were either symptom-free or had only slight residual headache on leaving."	1.26	Observations on the treatment of an acute attack of migraine. ( Leyton, M; Wilkinson, M; Williams, K, 1978)

Research

Studies (101)

Authors

Clinical Trials (11)

Trial Overview

Trial Outcomes

Clinical Duration

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (23.76)	18.7374
1990's	26 (25.74)	18.2507
2000's	24 (23.76)	29.6817
2010's	24 (23.76)	24.3611
2020's	3 (2.97)	2.80

Authors	Studies
Liu, G	1
Hrabe, J	1
Sanchez, R	1
Niño-Serna, LF	1
Acosta-Reyes, J	1
Veroniki, AA	1
Florez, ID	1
Friedman, BW	3
Irizarry, E	1
Williams, A	1
Solorzano, C	3
Zias, E	1
Robbins, MS	1
Harrilal, MA	1
Del Valle, M	1
Bijur, PE	2
Gallagher, EJ	3
Bath, PM	1
Lee, HS	1
Everton, LF	1
Numata, K	1
Shiga, T	1
Omura, K	1
Umibe, A	1
Hiraoka, E	1
Yamanaka, S	1
Azuma, H	1
Yamada, Y	1
Kobayashi, D	1
Sieminski, M	1
Zemojtel, L	1
Derry, S	1
Moore, RA	1
Rasmussen, ER	1
Pallesen, KA	1
Bygum, A	1
Choi, H	1
Parmar, N	1
Coloma, PM	1
Schuemie, MJ	1
Trifirò, G	1
Furlong, L	1
van Mulligen, E	1
Bauer-Mehren, A	1
Avillach, P	1
Kors, J	1
Sanz, F	1
Mestres, J	1
Oliveira, JL	1
Boyer, S	1
Helgee, EA	1
Molokhia, M	1
Matthews, J	1
Prieto-Merino, D	1
Gini, R	1
Herings, R	1
Mazzaglia, G	1
Picelli, G	1
Scotti, L	1
Pedersen, L	1
van der Lei, J	1
Sturkenboom, M	1
Saguil, A	1
Lax, JW	1
Shahrami, A	1
Assarzadegan, F	1
Hatamabadi, HR	1
Asgarzadeh, M	1
Sarehbandi, B	1
Asgarzadeh, S	1
Gaffigan, ME	1
Bruner, DI	1
Wason, C	1
Pritchard, A	1
Frumkin, K	1
Cabral, L	1
Adewunmi, V	1
Esses, D	2
Yaylak, F	1
Zeren, S	1
Bayhan, Z	1
Bademci, R	1
Devir, C	1
Kamata, K	1
Takahashi, E	1
Morioka, N	1
Nakashima, K	1
Iwade, M	1
Ozaki, M	1
Avcu, N	1
Doğan, NÖ	1
Pekdemir, M	1
Yaka, E	1
Yılmaz, S	1
Alyeşil, C	1
Akalın, LE	1
Schutz, J	1
Babl, FE	1
Sheriff, N	1
Borland, M	1
Alhashimi, D	3
Al-Hashimi, H	1
Fedorowicz, Z	4
Kumar, Y	1
Sarvananthan, R	1
Kelly, AM	1
Walcynski, T	1
Gunn, B	1
Yeoh, BS	1
Taylor, DM	1
Taylor, SE	1
Trepanier, L	1
Barkun, AN	1
Bardou, M	1
Martel, M	1
Gralnek, IM	1
Sung, JJ	1
Mulvey, L	1
Paternoster, J	1
Lipton, RB	1
Simpson, PM	1
Bendall, JC	1
Middleton, PM	1
Arriola-Villalobos, P	1
Iglesias-Lodares, I	1
Díaz-Valle, D	1
Garcia-Gil-de-Bernabé, J	1
Jagannath, VA	1
Carter, B	1
Olszewski, K	1
Stążka, J	1
Krawczyk, E	1
Kozłowicz, M	1
Cayley, WE	1
Bakhshayesh, B	1
Seyed Saadat, SM	1
Rezania, K	1
Hatamian, H	1
Hossieninezhad, M	1
Ahn, JH	1
Kang, YK	1
Kim, TW	1
Bahng, H	1
Chang, HM	1
Kang, WC	1
Kim, WK	1
Lee, JS	1
Park, JS	1
Kim, J	1
Riggs, KW	1
Rurak, DW	1
Cete, Y	1
Dora, B	1
Ertan, C	1
Ozdemir, C	1
Oktay, C	1
de Moor, RA	1
Diemont, WL	1
Visser, MO	1
van den Bemt, PM	1
Kabbouche, MA	1
Linder, SL	1
Bradshaw, M	1
Sen, A	1
van der Padt, A	1
van Schaik, RH	1
Sonneveld, P	1
Alhashimi, H	2
Hakkarainen, H	1
Allonen, H	1
Fernandes Filho, SM	1
Costa, MS	1
Fernandes, MT	1
Foerster, MV	1
Dingli, K	1
Morgan, R	1
Leen, C	1
Azzopardi, TD	1
Brooks, NA	1
Barnes, TR	1
Braude, WM	1
Hill, DJ	1
Ahmad, S	1
Leopold, NA	1
Röjdmark, S	1
Lamminpää, K	1
Miller, F	1
Fenzl, TC	1
Tfelt-Hansen, P	1
Olesen, J	2
Heron, JF	1
Scherl, ER	1
Wilson, JF	1
Sehgal, N	1
Anaya Ordóñez, S	1
Matas Hoces, A	1
Anderson, H	1
Thatcher, N	1
Howell, A	1
Logan, K	1
Sage, T	1
de Bruijn, KM	1
Saito, H	1
Shimokata, K	1
Yamori, S	1
Kajita, M	1
Niimi, T	1
Martín Carrasco, C	1
Rodríguez Vázquez, M	1
Palacios Garciá, R	1
Cameron, JD	1
Lane, PL	1
Speechley, M	1
Jones, J	1
Pack, S	1
Chun, E	1
Chevallier, B	1
Cappelaere, P	1
Splinter, T	1
Fabbro, M	1
Wendling, JL	1
Cals, L	1
Catimel, G	1
Giovannini, M	1
Khayat, D	1
Bastit, P	1
Claverie, N	1
Cubeddu, LX	1
Trujillo, LM	1
Talmaciu, I	1
Gonzalez, V	1
Guariguata, J	1
Seijas, J	1
Miller, IA	1
Paska, W	1
Modrego Pardo, P	1
Perez Trullen, JM	1
Khoo, VS	1
Rainford, K	1
Horwich, A	1
Dearnaley, DP	1
Drechsler, S	1
Bruntsch, U	1
Eggert, J	1
Grote-Kiehn, J	1
Gosse, H	1
Bangerter, M	1
Ukena, D	1
Oehm, C	1
Mezger, J	1
Faerber, L	1
Imhoff, W	1
Untch, M	1
Gallmeier, WM	1
Ward, TN	1
Hernández, J	1
Arés, A	1
Cantarero, S	1
García Ruiz, PJ	1
Malik, I	1
Moid, I	1
Khan, Z	1
Hussain, M	1
Palop, V	1
Jimenez, MJ	1
Catalán, C	1
Martínez-Mir, I	1
Catalán Arlandis, JL	1
Jiménez Torres, NV	1
Bosnjak, SM	1
Nesković-Konstantinović, ZB	1
Radulović, SS	1
Susnjar, S	1
Mitrovi, LB	1
McGinnis, J	1
Seaton, TL	1
Tait, PA	1
Hagen, EM	1
Farbu, E	1
Bindoff, L	1
van Der Kleij, FG	1
de Vries, PA	1
Stassen, PM	1
Sprenger, HG	1
Gans, RO	1
Geraud, G	1
Compagnon, A	1
Rossi, A	1
Aebelholt, A	1
Veilis, B	1
Wilkinson, M	2
Williams, K	1
Leyton, M	1
Ibsen, KK	1
Heilmann, C	1
Risbo, A	1
Rampton, DS	1
Zastrow, R	1
Christoffersen, J	1
Müller, TF	1
Naesh, O	1
Svare, E	1
Jensen, A	1
Glyngdal, P	1
Louvet, C	1
Lorange, A	1
Letendre, F	1
Beaulieu, R	1
Pretty, HM	1
Courchesne, Y	1
Neemeh, JA	1
Monte, M	1
Latreille, J	1
Riabrsev, VG	1
Iarema, IV	1
Dzheĭranov, FD	1
Mezvrishvili, GO	1
Fil'chev, MI	1
Gwynne, A	1
Arora, A	1
Nijhawan, S	1
Braun, U	1
Steiner, A	1
Kaegi, B	1
Milo, R	1
Neuman, M	1
Klein, C	1
Caspi, E	1
Arlazoroff, A	1
Santos, A	1
Arana, G	1
Sørensen, TT	1
Sørensen, PS	1
Vaghadia, H	1
Schou, H	1
Kongstad, LL	1
Morohashi, F	1
Aonuma, K	1
Katoh, M	1
Kobayashi, T	1
Hanaoka, Y	1
Tsuji, K	1
Norose, N	1
Kawai, H	1
Nakahata, T	1
Tsukada, M	1
Prusiński, A	1
Rózniecki, J	1
Durko, A	1
Głuszcz-Zielińska, A	1
Kozubski, W	1
Swatko, A	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Efficacy of Sodium Bicarbonate for Treatment of Acute Peripheral Vertigo: A Double-blinded Randomized Control Trial[NCT05676216]		225 participants (Anticipated)	Interventional	2023-01-07	Recruiting
A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872]	Phase 4	500 participants (Actual)	Interventional	2017-09-05	Terminated (stopped due to no longer recruiting or studying)
Effect of Intravenous Infusion of Magnesium Sulfate Associated or Not to Lidocaine On the Neuromuscular Blockade Induced by Muscle Relaxant Cistracurium[NCT02483611]	Phase 4	48 participants (Actual)	Interventional	2015-07-31	Completed
Diphenhydramine as Adjuvant Therapy for Acute Migraine. A Randomized Trial.[NCT01825941]	Phase 4	208 participants (Actual)	Interventional	2013-04-30	Completed
Sphenopalatine Ganglion Blocks for Headaches in the Emergency Department[NCT04255420]	Phase 4	84 participants (Anticipated)	Interventional	2020-02-21	Recruiting
A Randomized Controlled Trial of Metoclopramide Versus Placebo During Gastrojejunostomy Tube Placement for Facilitating Guidewire Advancement Through the Pylorus[NCT03331965]	Phase 2	110 participants (Actual)	Interventional	2018-04-09	Completed
Premedication With Metoclopramide in Upper Gastrointestinal Bleeds a Prospective Double Blinded Single Center Randomized Control Trial in a Small Community Hospital[NCT05746377]	Phase 4	60 participants (Anticipated)	Interventional	2023-05-20	Recruiting
A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708]		233 participants (Actual)	Interventional	2012-06-30	Completed
Erythromycin Versus Gastric Lavage to Improve Quality of Endoscopic Examination in Patients With Upper Gastrointestinal Bleeding. A Prospective Randomized Trial.[NCT01716572]	Phase 3	122 participants (Anticipated)	Interventional	2012-02-29	Active, not recruiting
Oral v. Parenteral Medications for the Emergency Management of Acute Migraine: a Pilot Randomized Control Trial[NCT05983354]		55 participants (Anticipated)	Interventional	2024-01-01	Not yet recruiting
A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache[NCT02440997]		46 participants (Actual)	Interventional	2015-03-25	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

"The clinical duration is the elapsed time for T1 recovery = 25% (Dur25%) of the original value of T1 after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Final Recovery Index

Intervention	minutes (Median)
Group M	82.68
Group ML	86.33
Group C	64.8

"The final recovery index is the elapsed time between the T1 recovery = 25% (Dur25%) and T4 / T1 = 80% (TOF = 80%) after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

HR - M1 (Heart Rate in the Moment 1)

Intervention	minutes (Mean)
Group M	27.97
Group ML	33.81
Group C	21.51

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The measure of heart rate was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of heart rate was performed when the patient arrived in the operating room

HR - M2 (Heart Rate in the Moment 2)

Intervention	beats/min (Mean)
Group M	79.94
Group ML	77.25
Group C	73.66

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before induction of anesthesia

HR - M3 (Heart Rate in the Moment 3)

Intervention	beats/min (Mean)
Group M	74.69
Group ML	73.69
Group C	75.40

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

HR - M4 (Heart Rate in the Moment 4)

Intervention	beats/min (Mean)
Group M	72.94
Group ML	74.19
Group C	75.40

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the end of the study solutions infusion. This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of heart rate was performed five minutes after M3 (in the end of the X and Y solutions infusion)

HR - M5 (Heart Rate in the Moment 5)

Intervention	beats/min (Mean)
Group M	71.94
Group ML	72.25
Group C	65.07

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the tracheal intubation

HR - M6 (Heart Rate in the Moment 6)

Intervention	beats/min (Mean)
Group M	67.56
Group ML	69.31
Group C	64.27

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of heart rate was performed one minute after the tracheal intubation

HR - M7a (Heart Rate in the Moment 7a)

Intervention	beats/min (Mean)
Group M	66.50
Group ML	68.19
Group C	65.13

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 15 minutes after the traqueal intubation.This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of heart rate was performed 15 minutes after the traqueal intubation

HR - M7b (Heart Rate in the Moment 7b)

Intervention	beats/min (Mean)
Group M	68.94
Group ML	68.19
Group C	67.13

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of heart rate was performed 30 minutes after the traqueal intubation

HR - M7c (Heart Rate in the Moment 7c)

Intervention	beats/min (Mean)
Group M	67.44
Group ML	68.38
Group C	64.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of heart rate was performed 45 minutes after the traqueal intubation

HR - M7d (Heart Rate in the Moment 7d)

Intervention	beats/min (Mean)
Group M	65.75
Group ML	65.75
Group C	62.33

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of heart rate was performed 60 minutes after the traqueal intubation

HR - M7e (Heart Rate in the Moment 7e)

Intervention	beats/min (Mean)
Group M	66.19
Group ML	65.31
Group C	61.93

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of heart rate was performed 75 minutes after the traqueal intubation

HR - M7f (Heart Rate in the Moment 7f)

Intervention	beats/min (Median)
Group M	66.50
Group ML	63.00
Group C	58.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of heart rate was performed 90 minutes after the traqueal intubation

Latency

Intervention	beats/min (Median)
Group M	66.00
Group ML	61.00
Group C	61.00

"The latency is computed as the elapsed time to reduce the response of T1 to 5% of the initial contraction force after the infusion of cisatracurium.~This outcome meansure was presented in seconds." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

MAP - M1 (Mean Arterial Pressure in the Moment 1)

Intervention	seconds (Mean)
Group M	139.70
Group ML	151.30
Group C	147.80

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed when the patient arrived in the operating room

MAP - M2 (Mean Arterial Pressure in the Moment 2)

Intervention	mmHg (Mean)
Group M	94.63
Group ML	88.75
Group C	100.10

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before induction of anesthesia

MAP - M3 (Mean Arterial Pressure in the Moment 3)

Intervention	mmHg (Mean)
Group M	87.63
Group ML	84.69
Group C	92.47

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

MAP - M4 (Mean Arterial Pressure in the Moment 4)

Intervention	mmHg (Mean)
Group M	75.88
Group ML	73.88
Group C	76.73

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the end of the study solutions infusion.This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed five minutes after M3 (in the end of the X and Y solutions infusion)

MAP - M5 (Mean Arterial Pressure in the Moment 5)

Intervention	mmHg (Median)
Group M	69.00
Group ML	63.00
Group C	74.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the tracheal intubation

MAP - M6 (Mean Arterial Pressure in the Moment 6)

Intervention	mmHg (Median)
Group M	62.50
Group ML	61.50
Group C	67.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed one minute after the tracheal intubation

MAP - M7a (Mean Arterial Pressure in the Moment 7a)

Intervention	mmHg (Median)
Group M	64.50
Group ML	64.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 15 minutes after the traqueal intubation. This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 15 minutes after the traqueal intubation

MAP - M7b (Mean Arterial Pressure in the Moment 7b)

Intervention	mmHg (Median)
Group M	66.00
Group ML	61.50
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 30 minutes after the traqueal intubation

MAP - M7c (Mean Arterial Pressure in the Moment 7c)

Intervention	mmHg (Median)
Group M	66.50
Group ML	63.50
Group C	68.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 45 minutes after the traqueal intubation

MAP - M7d (Mean Arterial Pressure in the Moment 7d)

Intervention	mmHg (Mean)
Group M	69.25
Group ML	63.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 60 minutes after the traqueal intubation

MAP - M7e (Mean Arterial Pressure in the Moment 7e)

Intervention	mmHg (Median)
Group M	68.00
Group ML	62.00
Group C	66.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 75 minutes after the traqueal intubation

MAP - M7f (Mean Arterial Pressure in the Moment 7f)

Intervention	mmHg (Median)
Group M	68.00
Group ML	66.00
Group C	69.00

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 90 minutes after the traqueal intubation

Recovery Index

Intervention	mmHg (Median)
Group M	64.00
Group ML	64.50
Group C	72.00

"The recovery index is the elapsed time between the T1 recovery =25% (Dur25%) and T1 =75% (Dur75%) after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Spontaneous Recovery (T4/T1=90%)

Intervention	minutes (Mean)
Group M	20.08
Group ML	20.26
Group C	14.53

"Spontaneous recovery is the elapsed time for the recovery of the TOF (T4 / T1) response to 90% of the original after infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: The participants were followed during the anesthetic - surgical procedure

Total Duration (Dur95%)

Intervention	minutes (Mean)
Group M	120.20
Group ML	126.70
Group C	90.03

"The total duration is the elapsed time for T1 recovery of the response to reach 95% of the initial after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Number of Participants With Sustained Headache Relief Assessed by Self-evaluation

Intervention	minutes (Mean)
Group M	113.20
Group ML	120.10
Group C	88.19

"Sustained headache relief is defined as achieving a headache level of mild or none within two hours and maintaining a level of mild or none for 48 hours. Patient self-evaluated pain level is solicited every half hour for two hours in the Emergency Department and then by telephone 48 hours after discharge from emergency department" (NCT01825941)
Timeframe: up to 2 hours in Emergency Department, 48 hours after discharge from Emergency Department

Number of Subjects Experiencing Adverse Effects in the Periprocedural Period

Intervention	Participants (Count of Participants)
Metoclopramide + Diphenhydramine	40
Metoclopramide + Placebo	38

To assess the safety of a single dose of promotility agent prior to GJ tube placement by assessing rates of adverse events in the periprocedural period in patients receiving IV metoclopramide versus placebo. (NCT03331965)
Timeframe: Up to 30 days after procedure.

Time to Duodenal Intubation

Intervention	Participants (Count of Participants)
Metoclopramide	0
Saline	0

The fluoroscopy time required to advance a guidewire through the pylorus. (NCT03331965)
Timeframe: Up to 45 minutes.

Total Procedure Air Kerma

Intervention	Minutes (Mean)
Metoclopramide	1.6
Saline	4.1

The total procedure Air Kerma (energy released in a unit mass of air) measured in milligray (mGy). (NCT03331965)
Timeframe: Up to 1 hour.

Total Procedure Fluoroscopy Time

Total Procedure Time

Hospital Length of Stay

Intervention	mGy (Mean)
Metoclopramide	91
Saline	130

Intervention	Minutes (Mean)
Metoclopramide	5.8
Saline	8.8

Intervention	Minutes (Mean)
Metoclopramide	16.4
Saline	19.9

Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours

Post-discharge Nausea

Intervention	hours (Median)
Intervention Cohort	26.4
Comparison Cohort	28.2

To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital

Post-discharge Vomiting

Post-operative Nausea

Intervention	percentage of subjects with PDN (Number)
Intervention Cohort	72
Comparison Cohort	60

Intervention	percentage of subjects with PDV (Number)
Intervention Cohort	22
Comparison Cohort	29

End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital

Article	Year
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. Pediatrics, 2020, Volume: 145, Issue:4 Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper	2020
Swallowing therapy for dysphagia in acute and subacute stroke. The Cochrane database of systematic reviews, 2018, 10-30, Volume: 10 Topics: Acupuncture Therapy; Acute Disease; Deglutition; Deglutition Disorders; Electric Stimulation Therapy	2018
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4 Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Therapy, Combinatio	2013
BET 1: Metoclopramide or prochlorperazine for headache in acute migraine? Emergency medicine journal : EMJ, 2013, Volume: 30, Issue:7 Topics: Acute Disease; Adult; Benchmarking; Emergency Service, Hospital; Evidence-Based Medicine; Humans; Me	2013
The use of intravenous magnesium sulphate for acute migraine: meta-analysis of randomized controlled trials. European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2014, Volume: 21, Issue:1 Topics: Acute Disease; Adult; Dopamine Antagonists; Double-Blind Method; Humans; Magnesium Sulfate; Metoclop	2014
Acute migraine treatment in emergency settings. American family physician, 2014, May-01, Volume: 89, Issue:9 Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Dexamethasone;	2014
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Acute Disease; Adolescent; Antiemetics; Child; Child, Preschool; Gastroenteritis; Humans; Metoclopra	2009
GORD in children. BMJ clinical evidence, 2008, Oct-01, Volume: 2008 Topics: Acute Disease; Administration, Oral; Child; Cross-Sectional Studies; Domperidone; Gastroesophageal R	2008
The relative efficacy of phenothiazines for the treatment of acute migraine: a meta-analysis. Headache, 2009, Volume: 49, Issue:9 Topics: Acute Disease; Clinical Trials as Topic; Dopamine Antagonists; Humans; Metoclopramide; Migraine Diso	2009
Acute vomiting in cats: rational treatment selection. Journal of feline medicine and surgery, 2010, Volume: 12, Issue:3 Topics: Acute Disease; Animals; Antiemetics; Cat Diseases; Cats; Chlorpromazine; Diarrhea; Famotidine; Indol	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointestinal endoscopy, 2010, Volume: 72, Issue:6 Topics: Acute Disease; Blood Transfusion; Duodenal Diseases; Endoscopy, Digestive System; Erythromycin; Esop	2010
Review article: Prophylactic metoclopramide for patients receiving intravenous morphine in the emergency setting: a systematic review and meta-analysis of randomized controlled trials. Emergency medicine Australasia : EMA, 2011, Volume: 23, Issue:4 Topics: Acute Disease; Analgesics, Opioid; Antiemetics; Dopamine Agonists; Emergencies; Humans; Injections,	2011
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. The Cochrane database of systematic reviews, 2011, Sep-07, Issue:9 Topics: Acute Disease; Adolescent; Antiemetics; Child; Child, Preschool; Fluid Therapy; Gastroenteritis; Hos	2011
Acute treatment of pediatric headache in the emergency department and inpatient settings. Pediatric annals, 2005, Volume: 34, Issue:6 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Dihydroergotamine; D	2005
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3 Topics: Acute Disease; Adolescent; Antiemetics; Child; Gastroenteritis; Humans; Metoclopramide; Ondansetron;	2006
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4 Topics: Acute Disease; Adolescent; Antiemetics; Child; Gastroenteritis; Humans; Metoclopramide; Ondansetron;	2006
Acute dystonic reaction caused by metoclopramide, versus tetanus. BMJ (Clinical research ed.), 2007, Apr-28, Volume: 334, Issue:7599 Topics: Acute Disease; Adult; Antiemetics; Diagnosis, Differential; Dystonia; Female; Humans; Medical Histor	2007
Oral metoclopramide as an adjunct to analgesics for the outpatient treatment of acute migraine. The Annals of pharmacotherapy, 2008, Volume: 42, Issue:3 Topics: Acute Disease; Administration, Oral; Ambulatory Care; Analgesics; Drug Synergism; Drug Therapy, Comb	2008
Management of an acute primary headache. Clinical neuroscience (New York, N.Y.), 1998, Volume: 5, Issue:1 Topics: Acute Disease; Cluster Headache; Dose-Response Relationship, Drug; Drug Administration Routes; Heada	1998
Metaclopramide neurotoxicity. Journal of the South Carolina Medical Association (1975), 1988, Volume: 84, Issue:11 Topics: Acute Disease; Aged; Basal Ganglia Diseases; Diagnosis, Differential; Duodenal Ulcer; Dyskinesia, Dr	1988

Article	Year
A Randomized, Double-Dummy, Emergency Department-Based Study of Greater Occipital Nerve Block With Bupivacaine vs Intravenous Metoclopramide for Treatment of Migraine. Headache, 2020, Volume: 60, Issue:10 Topics: Acute Disease; Administration, Intravenous; Adult; Anesthetics, Local; Bupivacaine; Cervical Plexus;	2020
Comparison of therapeutic effects of magnesium sulfate vs. dexamethasone/metoclopramide on alleviating acute migraine headache. The Journal of emergency medicine, 2015, Volume: 48, Issue:1 Topics: Acute Disease; Adult; Analgesics; Anti-Inflammatory Agents; Dexamethasone; Dopamine D2 Receptor Anta	2015
A Randomized Controlled Trial of Intravenous Haloperidol vs. Intravenous Metoclopramide for Acute Migraine Therapy in the Emergency Department. The Journal of emergency medicine, 2015, Volume: 49, Issue:3 Topics: Acute Disease; Adolescent; Adult; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Double-Bli	2015
Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. Annals of emergency medicine, 2016, Volume: 67, Issue:1 Topics: Acute Disease; Adult; Diphenhydramine; Dopamine D2 Receptor Antagonists; Double-Blind Method; Drug T	2016
Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. Annals of emergency medicine, 2016, Volume: 67, Issue:1 Topics: Acute Disease; Adult; Diphenhydramine; Dopamine D2 Receptor Antagonists; Double-Blind Method; Drug T	2016
Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. Annals of emergency medicine, 2016, Volume: 67, Issue:1 Topics: Acute Disease; Adult; Diphenhydramine; Dopamine D2 Receptor Antagonists; Double-Blind Method; Drug T	2016
Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. Annals of emergency medicine, 2016, Volume: 67, Issue:1 Topics: Acute Disease; Adult; Diphenhydramine; Dopamine D2 Receptor Antagonists; Double-Blind Method; Drug T	2016
Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial. Annals of emergency medicine, 2017, Volume: 69, Issue:6 Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Antiemetics; Double-Blind Meth	2017
Metoclopramide for acute migraine: a dose-finding randomized clinical trial. Annals of emergency medicine, 2011, Volume: 57, Issue:5 Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Analgesics; Dose-Response Relationship, Drug; Double-	2011
A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache. The American journal of emergency medicine, 2013, Volume: 31, Issue:3 Topics: Acute Disease; Adult; Analgesics; Dopamine Antagonists; Drug Therapy, Combination; Female; GABA Agen	2013
Nephrotoxicity of heptaplatin: a randomized comparison with cisplatin in advanced gastric cancer. Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:2 Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protoc	2002
A randomized prospective placebo-controlled study of intravenous magnesium sulphate vs. metoclopramide in the management of acute migraine attacks in the Emergency Department. Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:3 Topics: Academic Medical Centers; Acute Disease; Adult; Double-Blind Method; Emergency Medical Services; Fem	2005
Use of a prophylactic antiemetic with morphine in acute pain: randomised controlled trial. Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Female;	2006
Ergotamine vs. metoclopramide vs. their combination in acute migraine attacks. Headache, 1982, Volume: 22, Issue:1 Topics: Acute Disease; Adult; Dopamine Antagonists; Drug Therapy, Combination; Ergotamine; Female; Humans; M	1982
[Comparison of intravenous dipyrone to intravenous metoclopramide in the treatment of acute crisis of migraine: randomized clinical trial]. Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:4 Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dopamine Antagonists; Femal	2006
Does acute endogenous hyperprolactinemia affect intravenous glucose tolerance in humans? Metabolism: clinical and experimental, 1984, Volume: 33, Issue:6 Topics: Acute Disease; Adolescent; Adult; Aged; Bromocriptine; Female; Glucose Tolerance Test; Humans; Injec	1984
Single-agent oral granisetron for the prevention of acute cisplatin-induced emesis: a double-blind, randomized comparison with granisetron plus dexamethasone and high-dose metoclopramide plus dexamethasone. Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 10 Topics: Acute Disease; Administration, Oral; Adult; Aged; Cisplatin; Dexamethasone; Double-Blind Method; Dru	1995
Comparison of dihydroergotamine with metoclopramide versus meperidine with promethazine in the treatment of acute migraine. Headache, 1995, Volume: 35, Issue:5 Topics: Acute Disease; Adult; Ambulatory Care; Dihydroergotamine; Double-Blind Method; Drug Combinations; Fe	1995
Cisplatin-induced delayed emesis: pattern and prognostic factors during three subsequent cycles. Italian Group for Antiemetic Research. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:7 Topics: Acute Disease; Chi-Square Distribution; Cisplatin; Dexamethasone; Diphenhydramine; Drug Therapy, Com	1994
[Sumatriptan in the treatment of acute migraine: its role in primary health care]. Atencion primaria, 1994, Apr-30, Volume: 13, Issue:7 Topics: Acute Disease; Administration, Oral; Algorithms; Aspirin; Caffeine; Double-Blind Method; Drug Therap	1994
Tropisetron compared with a metoclopramide-based regimen in the prevention of chemotherapy-induced nausea and vomiting. European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:5 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Femal	1994
Continuous infusion versus intermittent short infusion of metoclopramide for cisplatin-induced acute emesis. American journal of clinical oncology, 1994, Volume: 17, Issue:5 Topics: Acute Disease; Adult; Aged; Chi-Square Distribution; Cisplatin; Female; Humans; Infusions, Intraveno	1994
Difference in persistence of efficacy of two antiemetic regimens on acute emesis during cisplatin chemotherapy. The Italian Group for Antiemetic Research. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:12 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antiemetics; Cisplatin; Dexamethasone; Diphenhydramin	1993
[A double-blind study of the analgesic efficacy in kidney colic of the combination of dipyrone and spasmolytic with ketorolac trometamol]. Archivos espanoles de urologia, 1993, Volume: 46, Issue:9 Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Butylscopolammonium Bromide; Colic; Dipyrone; Do	1993
Intravenous chlorpromazine vs intravenous metoclopramide in acute migraine headache. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1995, Volume: 2, Issue:7 Topics: Acute Disease; Adolescent; Adult; Aged; Chlorpromazine; Dopamine Antagonists; Double-Blind Method; E	1995
Intramuscular prochlorperazine versus metoclopramide as single-agent therapy for the treatment of acute migraine headache. The American journal of emergency medicine, 1996, Volume: 14, Issue:3 Topics: Acute Disease; Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Emergency Service, Hospi	1996
A double-blind, multicentre comparison of intravenous dolasetron mesilate and metoclopramide in the prevention of nausea and vomiting in cancer patients receiving high-dose cisplatin chemotherapy. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1997, Volume: 5, Issue:1 Topics: Acute Disease; Alcoholism; Antiemetics; Antineoplastic Agents; Basal Ganglia Diseases; Cisplatin; Do	1997
Antiemetic activity of ondansetron in acute gastroenteritis. Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1 Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Diarrhea; Female; Fluid Therapy; Gastroenteriti	1997
The effect of antiemetics and reduced radiation fields on acute gastrointestinal morbidity of adjuvant radiotherapy in stage I seminoma of the testis: a randomized pilot study. Clinical oncology (Royal College of Radiologists (Great Britain)), 1997, Volume: 9, Issue:4 Topics: Acute Disease; Adult; Antiemetics; Diarrhea; Gastrointestinal Diseases; Humans; Lymphatic Metastasis	1997
Comparison of three tropisetron-containing antiemetic regimens in the prophylaxis of acute and delayed chemotherapy-induced emesis and nausea. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1997, Volume: 5, Issue:5 Topics: Acute Disease; Adult; Aged; Antiemetics; Antineoplastic Agents; Dexamethasone; Drug Administration S	1997
Prospective randomized comparison of tropisetron with and without dexamethasone against high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. American journal of clinical oncology, 1999, Volume: 22, Issue:2 Topics: Acute Disease; Adult; Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Therapy, Co	1999
High efficacy of a single oral dose of ondansetron 8 mg versus a metoclopramide regimen in the prevention of acute emesis induced by fluorouracil, doxorubicin and cyclophosphamide (FAC) chemotherapy for breast cancer. Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:5 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemoth	2000
Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study. European neurology, 2002, Volume: 47, Issue:2 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug The	2002
Metoclopramide (Primperan) in the treatment of ureterolithiasis. A prospective double-blind study of metoclopramide compared with morphatropin on ureteral colic. Urologia internationalis, 1990, Volume: 45, Issue:2 Topics: Acute Disease; Atropine; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Metoclopra	1990

Article	Year
Colostomy as a definitive treatment in an ALS patient with acute colonic Pseudo-obstruction refractory to medical management, a case report. BMC neurology, 2022, Sep-22, Volume: 22, Issue:1 Topics: Acute Disease; Adult; Amyotrophic Lateral Sclerosis; Colonic Pseudo-Obstruction; Colostomy; Dioctyl	2022
Comparison of acute vertigo diagnosis and treatment practices between otolaryngologists and non-otolaryngologists: A multicenter scenario-based survey. PloS one, 2019, Volume: 14, Issue:3 Topics: Acute Disease; Female; Head Impulse Test; Humans; Male; Metoclopramide; Multivariate Analysis; Otola	2019
Acute Drug-Induced Symptoms of Restless Legs Syndrome in an Emergency Department. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019, 05-15, Volume: 15, Issue:5 Topics: Acute Disease; Adult; Dopamine D2 Receptor Antagonists; Emergency Service, Hospital; Female; Humans;	2019
Acute dystonia mimicking angioedema of the tongue: a video-illustrated case. BMJ case reports, 2013, Jul-08, Volume: 2013 Topics: Acute Disease; Angioedema; Dopamine Antagonists; Dystonia; Female; Humans; Metoclopramide; Middle Ag	2013
Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system. PloS one, 2013, Volume: 8, Issue:8 Topics: Acute Disease; Adverse Drug Reaction Reporting Systems; Azithromycin; Betamethasone; Cisapride; Domp	2013
Acute nontraumatic torticollis in a patient with right lower quadrant pain: case report. The Pan African medical journal, 2015, Volume: 21 Topics: Abdominal Pain; Acute Disease; Adolescent; Humans; Male; Metoclopramide; Torticollis	2015
[Metoclopramide Induced Acute Dystonia during Intravenous Patient-controlled Analgesia with Droperidol]. Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:10 Topics: Acute Disease; Adult; Analgesia, Patient-Controlled; Antiemetics; Droperidol; Dystonia; Female; Huma	2015
Emergency department management of gastro-enteritis in Australia and New Zealand. Journal of paediatrics and child health, 2008, Volume: 44, Issue:10 Topics: Acute Disease; Antiemetics; Australia; Data Collection; Dehydration; Diarrhea; Emergency Medicine; E	2008
Education initiative improves the evidence-based use of metoclopramide following morphine administration in the emergency department. Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:3 Topics: Acute Disease; Analgesics, Opioid; Antiemetics; Chi-Square Distribution; Emergency Medicine; Emergen	2009
[Pupillary block acute glaucoma due to acrylic intraocular lens posterior dislocation after Nd:YAG capsulotomy]. Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:9 Topics: Acute Disease; Aged; Brimonidine Tartrate; Combined Modality Therapy; Dipyrone; Drug Therapy, Combin	2011
Diagnostic difficulties of neurological complications after surgical treatment of acute ascending aorta dissection - a case report. Polski przeglad chirurgiczny, 2011, Volume: 83, Issue:2 Topics: Acute Disease; Adult; Antipsychotic Agents; Aortic Aneurysm, Thoracic; Aortic Dissection; Diagnosis,	2011
Antiemetics for acute gastroenteritis-related vomiting in children and adolescents. American family physician, 2012, Jun-01, Volume: 85, Issue:11 Topics: Acute Disease; Adolescent; Antiemetics; Child; Dimenhydrinate; Gastroenteritis; Humans; Metocloprami	2012
Effects of acute moderate hypoxemia on kinetics of metoclopramide and its metabolites in chronically instrumented sheep. Archives of pharmacal research, 2002, Volume: 25, Issue:5 Topics: Acute Disease; Animals; Female; Hypoxia; Metabolic Clearance Rate; Metoclopramide; Sheep	2002
[Urinary retention in 2 children after the use of antiemetic agents during acute gastroenteritis]. Nederlands tijdschrift voor geneeskunde, 2005, Jun-25, Volume: 149, Issue:26 Topics: Acute Disease; Antiemetics; Child, Preschool; Domperidone; Dopamine Antagonists; Female; Gastroenter	2005
Acute dystonic reaction to metoclopramide in patients carrying homozygous cytochrome P450 2D6 genetic polymorphisms. The Netherlands journal of medicine, 2006, Volume: 64, Issue:5 Topics: Acute Disease; Adult; Cytochrome P-450 CYP2D6; Dopamine Antagonists; Dystonia; Female; Humans; Leuke	2006
Acute akathisia after oral droperidol and metoclopramide preoperative medication. Lancet (London, England), 1982, Jul-03, Volume: 2, Issue:8288 Topics: Acute Disease; Akathisia, Drug-Induced; Droperidol; Eye Diseases; Female; Humans; Male; Metocloprami	1982
Metoclopramide-induced parkinsonism and severe edema. Southern medical journal, 1984, Volume: 77, Issue:10 Topics: Acute Disease; Edema; Humans; Male; Metoclopramide; Middle Aged; Parkinson Disease, Secondary	1984
Prolonged metoclopramide-induced dyskinetic reaction. Neurology, 1984, Volume: 34, Issue:2 Topics: Acute Disease; Adult; Benztropine; Female; Humans; Metoclopramide; Movement Disorders; Nausea; Time	1984
Prolonged ileus with acute spinal cord injury responding to metaclopramide. Paraplegia, 1981, Volume: 19, Issue:1 Topics: Acute Disease; Adult; Humans; Intestinal Obstruction; Male; Metoclopramide; Quadriplegia; Spinal Cor	1981
Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine. European neurology, 1980, Volume: 19, Issue:3 Topics: Acetaminophen; Acute Disease; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Humans;	1980
Index of suspicion. Case 3. Drug-induced movement disorder. Pediatrics in review, 1994, Volume: 15, Issue:10 Topics: Acute Disease; Child; Diagnosis, Differential; Dyskinesia, Drug-Induced; Female; Gastroenteritis; Hu	1994
Acute dyskinesias after metoclopramide withdrawal. Journal of the American Geriatrics Society, 1997, Volume: 45, Issue:4 Topics: Acute Disease; Aged; Aged, 80 and over; Dopamine Antagonists; Dyskinesia, Drug-Induced; Humans; Male	1997
[Acute familial dystonia caused by antidopaminergic drugs]. Neurologia (Barcelona, Spain), 1999, Volume: 14, Issue:1 Topics: Acute Disease; Adolescent; Benzamides; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dysto	1999
Acute dystonia associated with fluvoxamine-metoclopramide. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:3 Topics: Acute Disease; Adolescent; Antidepressive Agents; Dopamine Antagonists; Drug Interactions; Drug Ther	1999
Anthropometric and pharmacotherapeutic variables on acute emesis induced by cisplatin-containing chemotherapy. The Annals of pharmacotherapy, 2000, Volume: 34, Issue:5 Topics: Acute Disease; Age Factors; Antiemetics; Antineoplastic Agents; Body Weights and Measures; Chlorprom	2000
What is the optimal strategy for managing acute migraine headaches? The Journal of family practice, 2001, Volume: 50, Issue:2 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Disabled Persons; Drug	2001
Supraglottic dystonic reaction to metoclopramide in a child. The Medical journal of Australia, 2001, Jun-04, Volume: 174, Issue:11 Topics: Acute Disease; Age Factors; Antiemetics; Child; Dyspnea; Dystonia; Emergency Treatment; Glottis; Hum	2001
[Acute dystonia caused by metoclopramide (Afipran) therapy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2001, Aug-10, Volume: 121, Issue:18 Topics: Acute Disease; Adult; Antiemetics; Dyskinesia, Drug-Induced; Female; Humans; Male; Metoclopramide; P	2001
Acute dystonia due to metoclopramide: increased risk in AIDS. Archives of internal medicine, 2002, Feb-11, Volume: 162, Issue:3 Topics: Abdominal Pain; Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Antiemetics; Dystonia; Fol	2002
The Copenhagen Acute Headache Clinic: organization, patient material and treatment results. Headache, 1979, Volume: 19, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Anti-Anxiety Agents; Biperiden; Denmark; Female;	1979
Observations on the treatment of an acute attack of migraine. Research and clinical studies in headache, 1978, Volume: 6 Topics: Acute Disease; Analgesics; Diazepam; Ergotamine; Female; Headache; Humans; Hypnotics and Sedatives;	1978
[Uncharacteristic hypertonia resulting from treatment with metoclopramide (Primperan) in children with acute gastroenteritis]. Ugeskrift for laeger, 1977, Volume: 139, Issue:2 Topics: Acute Disease; Biperiden; Gastroenteritis; Humans; Infant; Male; Metoclopramide; Muscle Tonus; Muscu	1977
[Acute dystonia in children and young people caused by metoclopramide (Primperan). 2 cases from a casualty department]. Ugeskrift for laeger, 1977, Mar-28, Volume: 139, Issue:13 Topics: Acute Disease; Child; Female; Humans; Male; Metoclopramide; Muscle Tonus; Muscular Diseases	1977
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline. British medical journal, 1977, Sep-03, Volume: 2, Issue:6087 Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Human	1977
[Acute pancreatitis--pancreas necrosis]. Zeitschrift fur arztliche Fortbildung, 1975, Apr-15, Volume: 69, Issue:8 Topics: Acute Disease; Aprotinin; Atropine; Drainage; Fasting; Humans; Intestinal Obstruction; Metoclopramid	1975
[Acute dystonia during treatment with metoclopramide (Primperan). Report of 2 cases from general practice]. Ugeskrift for laeger, 1975, Mar-24, Volume: 137, Issue:13 Topics: Acute Disease; Adult; Dyspepsia; Female; Humans; Metoclopramide; Muscle Tonus; Muscular Diseases	1975
Acute and delayed emesis after cisplatin-based regimen: description and prevention. Oncology, 1991, Volume: 48, Issue:5 Topics: Acute Disease; Antiemetics; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Humans; Lora	1991
[Hemosorption and endolymphatic therapy in the treatment of paralytic ileus in peritonitis and acute intestinal obstruction]. Vestnik khirurgii imeni I. I. Grekova, 1990, Volume: 144, Issue:3 Topics: Acute Disease; Aged; Female; Gastrointestinal Motility; Hemoperfusion; Humans; Injections, Intralymp	1990
A nursing narrative. The Australian nurses' journal. Royal Australian Nursing Federation, 1990, Volume: 20, Issue:1 Topics: Acute Disease; Adult; Humans; Male; Metoclopramide; Nausea; Pancreatitis; Seizures; Vomiting	1990
Non-surgical treatment of acute upper gastrointestinal haemorrhage. The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:8 Topics: Acute Disease; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoclopramide;	1990
Clinical, haematological and biochemical findings and the results of treatment in cattle with acute functional pyloric stenosis. The Veterinary record, 1990, Feb-03, Volume: 126, Issue:5 Topics: Acute Disease; Alkalosis; Animals; Bile Acids and Salts; Cattle; Cattle Diseases; Chlorides; Female;	1990
Acute intermittent porphyria in pregnancy. Obstetrics and gynecology, 1989, Volume: 73, Issue:3 Pt 2 Topics: Acute Disease; Adult; Diagnosis, Differential; Female; Fluid Therapy; Genes, Dominant; Humans; Hyper	1989
Domperidone: an alternative to metoclopramide. Drug and therapeutics bulletin, 1988, Jul-25, Volume: 26, Issue:15 Topics: Acute Disease; Adolescent; Adult; Child; Domperidone; Humans; Metoclopramide; Nausea; Vomiting	1988
[Repeated acute dystonia following administration of metoclopramide and fluphenazine]. Ugeskrift for laeger, 1988, Mar-14, Volume: 150, Issue:11 Topics: Acute Disease; Adult; Dystonia; Female; Fluphenazine; Humans; Metoclopramide; Recurrence	1988
Acute abdominal distension in lactase deficiency relieved by metoclopramide. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, May-01, Volume: 134, Issue:9 Topics: Acute Disease; Adult; Colic; Humans; Lactose Intolerance; Male; Metoclopramide; Time Factors	1986
[Acute dystonia with fatal outcome. A possible adverse drug reaction in the simultaneous administration of chlorpromazine (Prozil) and metoclopramide (Primperan)]. Ugeskrift for laeger, 1986, Sep-08, Volume: 148, Issue:37 Topics: Acute Disease; Aged; Cerebral Hemorrhage; Chlorpromazine; Drug Therapy, Combination; Dystonia; Femal	1986
[Acute dystonia with fatal outcome]. Ugeskrift for laeger, 1986, Oct-27, Volume: 148, Issue:44 Topics: Acute Disease; Cerebral Hemorrhage; Dystonia; Hematoma, Subdural; Humans; Intracranial Aneurysm; Met	1986
[Modified VAPA therapy in children with acute nonlymphocytic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:11 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool;	1986
Migraine--treatment of acute attack. Scottish medical journal, 1985, Volume: 30, Issue:4 Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Mi	1985
[Acute dystonic reactions after administration of neuroleptics and other drugs]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Mar-01, Volume: 38, Issue:5 Topics: Acute Disease; Adult; Child; Droperidol; Dystonia; Female; Humans; Male; Metoclopramide; Middle Aged	1985

metoclopramide and Acute Disease