Page last updated: 2024-10-31

metoclopramide and ANS (Autonomic Nervous System) Diseases

metoclopramide has been researched along with ANS (Autonomic Nervous System) Diseases in 11 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Research Excerpts

ExcerptRelevanceReference
" Metoclopramide was administered for the treatment of gastroparesis."4.79Sinus arrest after administration of intravenous metoclopramide. ( Cruz-Flores, S; Gomez, CR; Malkoff, MD; Myles, GL; Ponzillo, JJ, 1995)
" While both cisapride and metoclopramide normalized impaired solid emptying, cisapride at its highest dosage (10 mg) resulted in significantly faster gastric emptying (P = 0."2.67Cisapride vs metoclopramide. An acute study in diabetic gastroparesis. ( Diamant, NE; Lico, S; McHugh, S, 1992)
"Treatment with metoclopramide hydrochloride and bethanechol chloride resulted in improved attitude, appetite, Schirmer tear test response, and decrease in frequency of vomiting within 24 hours."1.28A syndrome resembling feline dysautonomia (Key-Gaskell syndrome) in a dog. ( Lappin, MR; Wise, LA, 1991)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's6 (54.55)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feldman, M1
Schiller, LR1
Malkoff, MD1
Ponzillo, JJ1
Myles, GL1
Gomez, CR1
Cruz-Flores, S1
Ducla-Soares, JL1
Guerreiro, AS1
PĆ³voa, P1
Alvares, E1
Guerreiro, L1
Carrilho, F1
Santos, M1
Figueirinhas, J1
Carvalho, M1
Saito, T1
Miyai, I1
Matsumura, T1
Nozaki, S1
Kang, J1
Magnifico, F1
Pierangeli, G1
Barletta, G1
Candela, C1
Bonavina, G1
Contin, M1
Cortelli, P1
Norbiato, G1
Bevilacqua, M1
Righini, V1
Chebat, E1
Vago, T1
Bertora, P1
Castelli, L1
Mangoni, A1
McHugh, S1
Lico, S1
Diamant, NE1
Wise, LA1
Lappin, MR1
de Caestecker, JS1
Ewing, DJ1
Tothill, P1
Clarke, BF1
Heading, RC1
Williams, TD1
Lightman, SL1
Johnson, MR1
Carmichael, DJ1
Bannister, R1
Wright, RA1
Clemente, R1
Wathen, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622]Phase 23 participants (Actual)Interventional2014-07-31Terminated (stopped due to Lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metoclopramide and ANS (Autonomic Nervous System) Diseases

ArticleYear
Disorders of gastrointestinal motility associated with diabetes mellitus.
    Annals of internal medicine, 1983, Volume: 98, Issue:3

    Topics: Autonomic Nervous System Diseases; Bethanechol Compounds; Constipation; Diabetes Complications; Diab

1983
Sinus arrest after administration of intravenous metoclopramide.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:4

    Topics: Arrhythmia, Sinus; Autonomic Nervous System Diseases; Female; Gastroparesis; Humans; Injections, Int

1995
[Pure autonomic failure].
    Acta medica portuguesa, 1993, Volume: 6, Issue:11

    Topics: Autonomic Nervous System Diseases; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combinati

1993

Trials

3 trials available for metoclopramide and ANS (Autonomic Nervous System) Diseases

ArticleYear
The cardiovascular effects of metoclopramide in multiple system atrophy and pure autonomic failure.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2001, Volume: 11, Issue:3

    Topics: Aged; Autonomic Nervous System Diseases; Dopamine Antagonists; Female; Heart Rate; Hemodynamics; Hum

2001
Cisapride vs metoclopramide. An acute study in diabetic gastroparesis.
    Digestive diseases and sciences, 1992, Volume: 37, Issue:7

    Topics: Adult; Autonomic Nervous System Diseases; Cisapride; Diabetic Neuropathies; Dose-Response Relationsh

1992
Evaluation of oral cisapride and metoclopramide in diabetic autonomic neuropathy: an eight-week double-blind crossover study.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:1

    Topics: Adult; Autonomic Nervous System Diseases; Blood Glucose; Cisapride; Diabetic Neuropathies; Double-Bl

1989

Other Studies

5 other studies available for metoclopramide and ANS (Autonomic Nervous System) Diseases

ArticleYear
[A case of myotonic dystrophy with intestinal pseudo-obstruction syndrome].
    Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:10

    Topics: Acetylcholine; Adult; Antiemetics; Autonomic Nervous System Diseases; Fasting; Humans; Infusions, In

1999
Altered vasopressin response to metoclopramide in multiple system atrophy: evidence of a cholinergic defect in the hypothalamus.
    Acta neurologica Scandinavica, 1992, Volume: 85, Issue:4

    Topics: Autonomic Nervous System Diseases; Brain; Female; Humans; Hypothalamus; Male; Metoclopramide; Middle

1992
A syndrome resembling feline dysautonomia (Key-Gaskell syndrome) in a dog.
    Journal of the American Veterinary Medical Association, 1991, Jun-15, Volume: 198, Issue:12

    Topics: Animals; Autonomic Nervous System Diseases; Bethanechol; Bethanechol Compounds; Dog Diseases; Dogs;

1991
Selective defect in gonadotrophin secretion in patients with autonomic failure.
    Clinical endocrinology, 1989, Volume: 30, Issue:3

    Topics: Aged; Autonomic Nervous System Diseases; Follicle Stimulating Hormone; Gonadotropins; Growth Hormone

1989
Diabetic gastroparesis: an abnormality of gastric emptying of solids.
    The American journal of the medical sciences, 1985, Volume: 289, Issue:6

    Topics: Autonomic Nervous System Diseases; Beverages; Blood Glucose; Diabetic Neuropathies; Food; Gastric Em

1985