methysergide has been researched along with Ache in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (42.11) | 18.7374 |
| 1990's | 20 (26.32) | 18.2507 |
| 2000's | 15 (19.74) | 29.6817 |
| 2010's | 9 (11.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Divac, N; Medić, B; Prostran, M; Savić Vujović, K; Srebro, D; Stojanović, R; Vasović, D; Vučković, S | 1 |
| Fabris, D; Genaro, K; Prado, WA | 1 |
| Abelson, KS; Kanui, TI; Makau, CM; Towett, PK | 1 |
| Del Bel, EA; Dias, QM; Prado, WA; Silveira, JW | 1 |
| Prado, WA; Silva, JR; Silva, ML | 1 |
| de Oliveira, SM; Ferreira, J; Gomez, MV; Hoffmeister, C; Rossato, MF; Trevisan, G | 1 |
| Prado, WA; Reis, GM; Rossaneis, AC | 1 |
| Dias, QM; Fais, RS; Petronilho, A; Prado, WA; Reis, GM | 1 |
| Abrahão, RQ; Andrade, D; Dale, CS; Franciosi, AC; Giorgi, R; Juliano, L; Juliano, MA | 1 |
| Matsumoto, S; Takeda, M; Tanimoto, T | 1 |
| Brandão, ML; Castilho, VM; Macedo, CE | 1 |
| Calixto, JB; Cordeiro, RS; e Silva, PM; Lavich, TR; Martins, MA | 1 |
| Choi, SS; Han, EJ; Han, KJ; Kim, DH; Lee, HK; Lee, JK; Suh, HW | 1 |
| Choi, SS; Chung, KM; Han, EJ; Han, KJ; Lee, HK; Suh, HW | 1 |
| Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A | 1 |
| Chen, Y; Oatway, MA; Weaver, LC | 1 |
| Reid, AR; Sawynok, J; Waldron, JB | 1 |
| Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H | 1 |
| Meienberg, O; Orfei, R | 1 |
| Hirota, N; Kuraishi, Y; Satoh, M; Sugimoto, M; Takagi, H | 1 |
| Carstens, E; Fraunhoffer, M; Zimmermann, M | 1 |
| Clementi, G; Conforto, G; Prato, A; Scapagnini, U | 1 |
| Kondzielski, MH; Larson, AA | 1 |
| Gintautas, J; Hughston, T; Kraynack, B; Racz, G; Thomas, E | 1 |
| Gebhart, GF; Kolhekar, R; Meller, ST | 1 |
| Akunne, HC; Soliman, KF | 1 |
| Acquadro, MA; Chen, VN; Rubin, PA | 1 |
| Choi, YS; Do, JC; Kim, YH; Lee, KH; Son, KH; Song, DK; Suh, HW; Woo, MH | 1 |
| Franco, AC; Prado, WA | 1 |
| Coimbra, NC; Mamede Rosa, ML; Oliveira, MA; Prado, WA; Valente, RB | 1 |
| Hammond, DL; Nelson, V; Thomas, DA | 1 |
| Kawamata, M; Kawamata, T; Namiki, A; Omote, K | 1 |
| Takagi, J; Yonehara, N | 1 |
| Guimarães, AP; Guimarães, FS; Prado, WA | 1 |
| Goto, T; Ochi, T | 1 |
| Kawabata, A; Kawao, N; Kuroda, R; Shigenaga, Y; Takemura, M; Umeda, W; Yoshimura, H | 1 |
| Brandão, ML; Castilho, VM | 1 |
| Ahn, DK; Ju, JS; Kim, KH; Kwon, S; Park, JS | 1 |
| Everhart, AW; Fullwood, SD; Hains, BC; Hulsebosch, CE | 1 |
| Jerusalem, F; Mattle, H | 1 |
| Spierings, EL | 1 |
| Andreas, K; Dude, C; Dude, G | 1 |
| Prusiner, S; Raskin, NH | 1 |
| DuChateau, JC; Rudy, TA; Yaksh, TL | 1 |
| Bauer, MB; Gebhart, GF; Meller, ST | 1 |
| Giordano, J; Schomburg, FM; Sufka, KJ | 1 |
| Hua, M; Mense, S; Yu, XM | 1 |
| Alhaider, AA | 1 |
| Chorev, M; Devor, M; Gilon, C; Papir-Kricheli, D; Selinger, Z | 1 |
| Li, YJ; Qiao, JT; Xie, YF | 1 |
| Gebhart, GF; Zhuo, M | 1 |
| Miller, JF; Proudfit, HK | 1 |
| Isbrucker, R; Reid, A; Sawynok, J | 1 |
| Collins, JG; Iwasaki, H; Saito, Y | 1 |
| Collins, JG; Kitahata, LM; Murata, K; Nakagawa, I; Omote, K | 1 |
| Barber, A; Harting, J; Wolf, HP | 1 |
| Tang, R; Tseng, LL | 1 |
| Boja, JW; Crisp, T; Schechter, MD; Stafinsky, JL | 1 |
| Dafny, N; Qiao, JT; Reyes-Vazquez, C | 1 |
| Gebhart, GF; Randich, A; Ren, K | 1 |
| Aimone, LD; Gebhart, GF | 1 |
| Gebhart, GF; Janss, AJ | 1 |
| de Ceballos, ML; de Felipe, MC; Fuentes, JA | 1 |
| Barbaro, NM; Fields, HL; Hammond, DL | 1 |
| Carstens, E; Guinan, MJ; Pretel, S | 1 |
| Sandkühler, J; Zimmermann, M | 1 |
| Emmers, R; Tamir, H; Wilchek, M | 1 |
| Proudfit, HK; Sagen, J | 1 |
| Abbott, FV; Connell, B; Franklin, KB | 1 |
| Collier, HO; James, GW; Schneider, C | 1 |
| Courtois, H; Dubuisson, M; Schrub, JC; Wolf, LM | 1 |
| Goodell, H | 1 |
| Tyler, HR | 1 |
| Pepper, H | 1 |
| Gdynia, R; Wilhelmi, G | 1 |
1 review(s) available for methysergide and Ache
| Article | Year |
|---|---|
Advances in neurology.
Topics: Analgesics; Anticoagulants; Brain; Brain Neoplasms; Carbamazepine; Cerebrovascular Disorders; Contraceptives, Oral; Diazepam; Encephalitis; Headache; Humans; Intracranial Aneurysm; Methysergide; Multiple Sclerosis; Muscular Diseases; Neuralgia; Pain; Parkinson Disease; Seizures; Tic Disorders | 1968 |
75 other study(ies) available for methysergide and Ache
| Article | Year |
|---|---|
Involvement of serotonergic and opioidergic systems in the antinociceptive effect of ketamine-magnesium sulphate combination in formalin test in rats.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Formaldehyde; Ketamine; Magnesium Sulfate; Male; Methysergide; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Serotonergic Neurons | 2019 |
The antinociceptive effect of anterior pretectal nucleus stimulation is mediated by distinct neurotransmitter mechanisms in descending pain pathways.
Topics: Analgesia; Analgesics, Opioid; Animals; Electric Stimulation; Male; Methysergide; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Nociceptors; Pain; Pain Management; Pain Measurement; Pedunculopontine Tegmental Nucleus; Pretectal Region; Rats; Rats, Wistar | 2019 |
Intrathecal administration of clonidine or yohimbine decreases the nociceptive behavior caused by formalin injection in the marsh terrapin (Pelomedusa subrufa).
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Injections, Spinal; Methysergide; Pain; Pain Measurement; Random Allocation; Serotonin Antagonists; Turtles; Yohimbine | 2014 |
Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats.
Topics: Animals; Atropine; Cholinergic Antagonists; Immunohistochemistry; Ketanserin; Male; Methiothepin; Methysergide; Neurons; Norepinephrine; Pain; Pain Measurement; Pain, Postoperative; Phenoxybenzamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord | 2010 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; Atropine; Baclofen; Bicuculline; Biophysics; Dioxanes; Disease Models, Animal; Electroacupuncture; GABA Agents; Male; Methysergide; Models, Biological; Multivariate Analysis; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Serotonin Antagonists; Tail; Thiopental; Time Factors | 2011 |
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cinnamates; Cromolyn Sodium; Disease Models, Animal; Diterpenes; Edema; Gabexate; Histamine; Male; Mast Cells; Methysergide; Pain; Promethazine; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Serotonin; Serotonin Antagonists; Tritium; TRPV Cation Channels; Uric Acid | 2011 |
Stimulation of the occipital or retrosplenial cortex reduces incision pain in rats.
Topics: Analgesics; Animals; Atropine; Cerebral Cortex; Electric Stimulation; Lidocaine; Male; Methysergide; Naloxone; Pain; Rats; Rats, Wistar | 2011 |
Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Pain; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Subthalamic Nucleus; Subthalamus | 2012 |
Oligopeptidases B from Trypanossoma cruzi and Trypanossoma brucei inhibit inflammatory pain in mice by targeting serotoninergic receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Male; Methysergide; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Serotonin; Serine Endopeptidases; Serotonin Antagonists; Trypanosoma brucei brucei; Trypanosoma cruzi; Yohimbine | 2013 |
Suppressive effect of vagal afferents on cervical dorsal horn neurons responding to tooth pulp electrical stimulation in the rat.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Dental Pulp; Dose-Response Relationship, Drug; Efferent Pathways; Electric Stimulation; Electromyography; Male; Methysergide; Muscle Contraction; Neural Inhibition; Nociceptors; Norepinephrine; Pain; Phenoxybenzamine; Posterior Horn Cells; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Trigeminal Nerve; Trigeminal Nuclei; Vagus Nerve; Visceral Afferents | 2002 |
Role of benzodiazepine and serotonergic mechanisms in conditioned freezing and antinociception using electrical stimulation of the dorsal periaqueductal gray as unconditioned stimulus in rats.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Conditioning, Classical; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Male; Methysergide; Microinjections; Midazolam; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Serotonin; Serotonin Antagonists | 2002 |
Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats.
Topics: Allergens; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyproheptadine; Dinitrophenols; Dose-Response Relationship, Drug; Drug Synergism; Edema; Histamine; Histamine H1 Antagonists; Hyperalgesia; Immunoglobulin E; Male; Meclizine; Methysergide; Pain; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serum Albumin, Bovine; Time Factors | 2003 |
Antinociceptive mechanisms of orally administered decursinol in the mouse.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzopyrans; Butyrates; Cyproheptadine; Dose-Response Relationship, Drug; Glutamic Acid; Histamine H2 Antagonists; Interferon-gamma; Interleukin-1; Male; Methysergide; Mice; Mice, Inbred ICR; Models, Chemical; Naloxone; Narcotic Antagonists; Pain; Piperidines; Protein Kinase C; Ranitidine; Receptors, Adrenergic; Receptors, Histamine; Receptors, Purinergic P1; Receptors, Serotonin; Serotonin Antagonists; Substance P; Theobromine; Tumor Necrosis Factor-alpha; Xanthines; Yohimbine | 2003 |
Antinociceptive effects of methysergide in various pain models.
Topics: Analgesia; Animals; Behavior, Animal; Formaldehyde; Injections, Intraperitoneal; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Pain; Serotonin Antagonists | 2003 |
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord.
Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine | 2003 |
The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury.
Topics: 5,6-Dihydroxytryptamine; Animals; Behavior, Animal; Biguanides; Dose-Response Relationship, Drug; Drug Interactions; Escape Reaction; Hyperesthesia; Immunohistochemistry; Male; Methysergide; Neurotoxins; Ondansetron; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Time Factors | 2004 |
Amitriptyline produces multiple influences on the peripheral enhancement of nociception by P2X receptors.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Hyperalgesia; Male; Methysergide; Pain; Phentolamine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Serotonin Antagonists | 2004 |
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine | 2005 |
Carotidynia: report of eight cases and prospective evaluation of therapy.
Topics: Adult; Aged; Carotid Artery Diseases; Dihydroergotamine; Female; Flurbiprofen; Humans; Indomethacin; Male; Methysergide; Middle Aged; Pain; Syndrome | 1983 |
Effects of morphine on noxious stimuli-induced release of substance P from rabbit dorsal horn in vivo.
Topics: Animals; Male; Methysergide; Morphine; Naloxone; Pain; Prazosin; Rabbits; Spinal Cord; Substance P | 1983 |
Serotonergic mediation of descending inhibition from midbrain periaqueductal gray, but not reticular formation, or spinal nociceptive transmission in the cat.
Topics: Animals; Brain Mapping; Cats; Fenclonine; Hot Temperature; Mesencephalon; Methysergide; Neural Inhibition; Pain; Reticular Formation; Serotonin; Spinal Cord; Synaptic Transmission | 1981 |
Role of serotonin in the analgesic activity of calcitonin.
Topics: Analgesics; Animals; Calcitonin; Drug Antagonism; Male; Methysergide; Norepinephrine; Pain; Phentolamine; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin | 1984 |
Serotonin-induced gnawing in rats: comparison with tail pinch-induced gnawing.
Topics: Animals; Dopamine; Haloperidol; Humans; Injections, Intraperitoneal; Injections, Spinal; Methysergide; Pain; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior; Synapses | 1982 |
Activation of coerulospinal systems by nociceptive stimulus.
Topics: Animals; Cats; Electric Stimulation; Female; Hindlimb; Locus Coeruleus; Male; Methysergide; Pain; Phenoxybenzamine; Spinal Cord | 1981 |
Characterization of the role of spinal N-methyl-D-aspartate receptors in thermal nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cold Temperature; Hot Temperature; Male; Methysergide; N-Methylaspartate; Nitroarginine; Nociceptors; Pain; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1993 |
Serotonin modulation of pain responsiveness in the aged rat.
Topics: Aging; Animals; Drug Synergism; Fluoxetine; Male; Methysergide; Morphine; Pain; Pain Measurement; Rats; Rats, Inbred F344; Reaction Time; Serotonin | 1994 |
Cluster headache presenting with orbital inflammation.
Topics: Adult; Cluster Headache; Endophthalmitis; Humans; Inflammation; Male; Methysergide; Orbital Diseases; Pain; Vasoconstrictor Agents | 1996 |
Antinociceptive effect of smilaxin B administered intracerebroventricularly in the mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cerebral Ventricles; Dizocilpine Maleate; Glycosides; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Muscimol; Naloxone; Pain; Sincalide; Spinal Cord; Spirostans; Yohimbine | 1996 |
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists; Electric Stimulation; Haloperidol; Hypothalamic Area, Lateral; Male; Mecamylamine; Methysergide; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists | 1996 |
Pharmacological and neuroanatomical evidence for the involvement of the anterior pretectal nucleus in the antinociception induced by stimulation of the dorsal raphe nucleus in rats.
Topics: Afferent Pathways; Amidines; Anesthetics, Local; Animals; Electric Stimulation; Fluorescent Dyes; Lidocaine; Male; Mesencephalon; Methysergide; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nociceptors; Pain; Pain Measurement; Raphe Nuclei; Rats; Rats, Wistar; Serotonin Antagonists; Tail | 1998 |
Intrathecal methysergide antagonizes the antinociception, but not the hyperalgesia produced by microinjection of baclofen in the ventromedial medulla of the rat.
Topics: Analgesics; Animals; Baclofen; GABA-B Receptor Antagonists; Hyperalgesia; Injections, Spinal; Male; Medulla Oblongata; Methysergide; Microinjections; Pain; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 1998 |
Formalin-induced nociception activates a monoaminergic descending inhibitory system.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Biogenic Monoamines; Formaldehyde; Male; Methysergide; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Yohimbine | 1998 |
Serotonin receptor subtypes involved in modulation of electrical acupuncture.
Topics: Animals; Dental Pulp; Electric Stimulation; Electroacupuncture; Evoked Potentials; Indoles; Injections, Intravenous; Ketanserin; Male; Methysergide; Nociceptors; Pain; Pindolol; Piperazines; Rabbits; Receptors, Serotonin; Serotonin Antagonists; Trigeminal Caudal Nucleus; Tropisetron | 1998 |
Modulation of carbachol-induced antinociception from the rat periaqueductal gray.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Anxiety; Bethanechol; Carbachol; Cholinergic Agonists; Dimethylphenylpiperazinium Iodide; Male; Maze Learning; Methysergide; Muscarinic Agonists; Naloxone; Narcotic Antagonists; Nicotinic Agonists; Nociceptors; Pain; Pain Measurement; Periaqueductal Gray; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists; Vocalization, Animal | 2000 |
The antinociceptive effect induced by FR140423 is mediated through spinal 5-HT2A and 5-HT3 receptors.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Ketanserin; Male; Methysergide; Mice; Pain; Pain Measurement; Piperazines; Pyrazoles; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Sulfoxides; Tropanes | 2000 |
Secondary somatosensory cortex stimulation facilitates the antinociceptive effect of the NO synthase inhibitor through suppression of spinal nociceptive neurons in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Injections, Spinal; Male; Methysergide; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nociceptors; Pain; Pain Measurement; Phentolamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin Antagonists; Somatosensory Cortex; Spinal Cord | 2001 |
Conditioned antinociception and freezing using electrical stimulation of the dorsal periaqueductal gray or inferior colliculus as unconditioned stimulus are differentially regulated by 5-HT2A receptors in rats.
Topics: Animals; Autonomic Nervous System; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Electric Stimulation; Inferior Colliculi; Ketanserin; Male; Methysergide; Microinjections; Pain; Pain Measurement; Pain Threshold; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Tectum Mesencephali | 2001 |
Microinjection of arginine vasopressin into the central nucleus of amygdala suppressed nociceptive jaw opening reflex in freely moving rats.
Topics: Adrenergic alpha-Antagonists; Amygdala; Animals; Arginine Vasopressin; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Male; Masticatory Muscles; Methysergide; Microinjections; Movement; Muscle Contraction; Naloxone; Narcotic Antagonists; Neurons; Nociceptors; Pain; Pain Measurement; Phentolamine; Rats; Rats, Sprague-Dawley; Reflex; Serotonin Antagonists | 2001 |
Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat.
Topics: Animals; Blotting, Western; Carrier Proteins; Denervation; Enzyme-Linked Immunosorbent Assay; Fluvoxamine; Hot Temperature; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methysergide; Motor Activity; Nerve Tissue Proteins; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Spinal Cord; Spinal Cord Injuries | 2002 |
[Exercise-induced muscular weakness, myalgia and contractures. I. A clinical review].
Topics: Acidosis; Adolescent; Adult; Arteriosclerosis; Child; Diagnosis, Differential; Energy Metabolism; Ergotism; Female; Glucose-6-Phosphate Isomerase; Glycogen Storage Disease Type V; Humans; Lactates; Lipid Metabolism, Inborn Errors; Male; Methysergide; Muscles; Muscular Diseases; Myoglobinuria; Myotonia Congenita; Pain; Phosphofructokinase-1; Physical Exertion; Water-Electrolyte Imbalance | 1977 |
Endogenous pain control mechanisms.
Topics: Feedback; Humans; Methysergide; Migraine Disorders; Pain | 1979 |
[Role of the serotoninergic raphe-hippocampus system for the antinocifensive effect of morphine].
Topics: Animals; Brain Stem; Corpus Striatum; Dose-Response Relationship, Drug; Drug Antagonism; Female; Hippocampus; Lysergic Acid Diethylamide; Methysergide; Morphine; Pain; Raphe Nuclei; Rats; Serotonin | 1979 |
Carotidynia.
Topics: Adult; Aged; Carotid Artery Diseases; Dose-Response Relationship, Drug; Ergonovine; Female; Headache; Humans; Jaw Diseases; Methysergide; Middle Aged; Migraine Disorders; Nortriptyline; Pain; Propranolol | 1977 |
Antagonism by methysergide and cinanserin of the antinociceptive action of morphine administered into the periaqueductal gray.
Topics: Animals; Brain Mapping; Cerebral Aqueduct; Cinanserin; Cinnamates; Male; Methysergide; Morphine; Pain; Rats; Serotonin | 1976 |
Bradykinin modulation of a spinal nociceptive reflex in the rat.
Topics: Analysis of Variance; Animals; Blood Pressure; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Heart Rate; Methysergide; Nociceptors; Pain; Phentolamine; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Vagus Nerve | 1992 |
Receptor mediation of 5-HT-induced inflammation and nociception in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Imidazoles; Inflammation; Ketanserin; Male; Methysergide; Ondansetron; Pain; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1992 |
The effects of intracerebroventricular injection of naloxone, phentolamine and methysergide on the transmission of nociceptive signals in rat dorsal horn neurons with convergent cutaneous-deep input.
Topics: Animals; Endorphins; Female; Injections, Intraventricular; Male; Methysergide; Muscles; Naloxone; Neurons, Afferent; Nociceptors; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Skin; Spinal Cord; Synaptic Transmission | 1991 |
Antinociceptive effect of ketanserin in mice: involvement of supraspinal 5-HT2 receptors in nociceptive transmission.
Topics: Acetates; Acetic Acid; Adrenergic alpha-Antagonists; Analgesics; Animals; Brain Chemistry; Dioxanes; Dopamine; Idazoxan; Ketanserin; Male; Methysergide; Mice; Norepinephrine; Pain; Reaction Time; Receptors, Serotonin; Serotonin; Synaptic Transmission | 1991 |
Neurochemical mediators of the behavioural effects of receptor-selective substance P agonists administered intrathecally in the rat.
Topics: Animals; Injections, Spinal; Male; Methysergide; Morphine; Muscles; Naloxone; Pain; Peptide Fragments; Phentolamine; Phenylephrine; Posture; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereotyped Behavior; Substance P | 1990 |
Effects of intrathecal monoamine antagonists and naloxone on the descending inhibition of the spinal transmission of noxious input in rats: study with a new experimental model.
Topics: Animals; Female; Injections, Spinal; Male; Methysergide; Naloxone; Neurons; Pain; Peroneal Nerve; Phentolamine; Rats; Rats, Inbred Strains; Spinal Cord | 1991 |
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat.
Topics: Amidines; Analysis of Variance; Animals; Atropine; Blood Pressure; Brain; Electric Stimulation; Heart Rate; Hot Temperature; Injections, Spinal; Male; Mecamylamine; Medulla Oblongata; Methysergide; Naloxone; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin Antagonists; Sodium Glutamate; Spinal Cord; Tropanes | 1991 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Female; Injections, Spinal; Methysergide; Microinjections; Naloxone; Neurons; Pain; Phentolamine; Pons; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1990 |
Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord.
Topics: 5,7-Dihydroxytryptamine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Synergism; Hot Temperature; Hydroxydopamines; Male; Methysergide; Norepinephrine; Oxidopamine; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline | 1990 |
Tonic 5-HT modulation of spinal dorsal horn neuron activity evoked by both noxious and non-noxious stimuli: a source of neuronal plasticity.
Topics: Action Potentials; Animals; Cats; Methysergide; Neuronal Plasticity; Pain; Serotonin; Spinal Cord | 1990 |
Serotonergic mediation of spinal analgesia and its interaction with noradrenergic systems.
Topics: Anesthesia, Spinal; Animals; Cats; Female; Injections, Intravenous; Injections, Spinal; Male; Methysergide; Naloxone; Neurons; Pain; Serotonin; Serotonin Antagonists; Yohimbine | 1990 |
Antinociceptive effects of the 5-HT2 antagonist ritanserin in rats: evidence for an activation of descending monoaminergic pathways in the spinal cord.
Topics: Animals; Methysergide; Nociceptors; Pain; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Spinal Cord; Yohimbine | 1989 |
Differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats.
Topics: Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mesencephalon; Methysergide; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Spinal Cord; Yohimbine | 1989 |
The antinociceptive effects of 3,4-methylenedioxymethamphetamine (MDMA) in the rat.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analgesics; Animals; Dose-Response Relationship, Drug; Male; Methysergide; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Pain; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1989 |
Nociceptive responses in nucleus parafascicularis thalami are modulated by dorsal raphe stimulation and microiontophoretic application of morphine and serotonin.
Topics: Action Potentials; Animals; Male; Methysergide; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Thalamic Nuclei | 1989 |
Vagal afferent modulation of a nociceptive reflex in rats: involvement of spinal opioid and monoamine receptors.
Topics: Afferent Pathways; Animals; Blood Pressure; Electric Stimulation; Hot Temperature; Injections, Spinal; Male; Methysergide; Naloxone; Nociceptors; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Opioid; Reflex; Spinal Cord; Vagus Nerve | 1988 |
Serotonin and/or an excitatory amino acid in the medial medulla mediates stimulation-produced antinociception from the lateral hypothalamus in the rat.
Topics: Amino Acids; Animals; Electric Stimulation; Hypothalamic Area, Lateral; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1988 |
Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus.
Topics: Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hot Temperature; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Yohimbine | 1987 |
Hypoalgesia induced by antidepressants in mice: a case for opioids and serotonin.
Topics: Amitriptyline; Animals; Antidepressive Agents; Dibenzazepines; Drug Tolerance; Endorphins; Fenclonine; Imipramine; Iprindole; Male; Methysergide; Mice; Mice, Inbred ICR; Naloxone; Pain; Protease Inhibitors; Serotonin | 1986 |
Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat.
Topics: Animals; Electric Stimulation; Foot; Male; Methysergide; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Tail; Yohimbine | 1985 |
Inhibition of the responses of cat dorsal horn neurons to noxious skin heating by stimulation in medial or lateral medullary reticular formation.
Topics: Action Potentials; Afferent Pathways; Animals; Cats; Electric Stimulation; Female; Hot Temperature; Male; Medulla Oblongata; Methysergide; Neural Inhibition; Pain; Phentolamine; Raphe Nuclei; Reticular Formation; Skin; Spinal Cord | 1988 |
Neuronal effects of controlled superfusion of the spinal cord with monoaminergic receptor antagonists in the cat.
Topics: Animals; Cats; Methysergide; Naloxone; Nociceptors; Pain; Perfusion; Phentolamine; Spinal Cord | 1988 |
Influence of a serotonin receptor antagonist, 5-HTP-DP-hex, on spinal and thalamic nociceptive neurons in rats.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Ketanserin; Male; Methysergide; Naloxone; Nerve Fibers; Pain; Periaqueductal Gray; Rats; Reaction Time; Sciatic Nerve; Spinothalamic Tracts; Thalamic Nuclei | 1987 |
Alterations in nociception following lesions of the A5 catecholamine nucleus.
Topics: Adrenergic Fibers; Animals; Brain Mapping; Female; Injections, Spinal; Methysergide; Norepinephrine; Pain; Phentolamine; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1986 |
The stress of a novel environment reduces formalin pain: possible role of serotonin.
Topics: Animals; Environment; Formaldehyde; Habituation, Psychophysiologic; Methysergide; Naloxone; Pain; Rats; Serotonin; Stress, Psychological; Valine | 1986 |
Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Atropine; Bradykinin; Bronchi; Dinitrophenols; Drug Antagonism; Ethanolamines; Flufenamic Acid; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Mefenamic Acid; Methysergide; Mice; ortho-Aminobenzoates; Pain; SRS-A; Tryptamines | 1966 |
[The course of retroperitoneal fibrosis due to methysergide].
Topics: Age Factors; Female; Humans; Hypertension; Kidney Failure, Chronic; Methysergide; Middle Aged; Pain; Prognosis; Retroperitoneal Fibrosis; Sex Factors; Urinary Tract Infections; Urography; Vascular Diseases; Vena Cava, Inferior | 1973 |
Headache mechanisms. II.
Topics: Animals; Blood Vessels; Headache; Intracranial Pressure; Methysergide; Migraine Disorders; Nerve Tissue Proteins; Pain; Rats; Vascular Headaches; Vasodilator Agents | 1973 |
Seminar on headache.
Topics: Benzocycloheptenes; Diagnosis, Differential; Ergotamine; Headache; Humans; Methysergide; Migraine Disorders; Pain; Piperidines; Thiophenes | 1971 |
Primary erythermalgia. Report of a patient treated with methysergide maleate.
Topics: Aspirin; Caffeine; Codeine; Edema; Erythromelalgia; Female; Humans; Maleates; Methysergide; Middle Aged; Pain; Phenacetin | 1968 |
[On the phlogogenic properties of lactic acid in animal experiments].
Topics: Animals; Capillary Permeability; Conjunctivitis; Edema; Exudates and Transudates; Guinea Pigs; Inflammation; Lactates; Leukocyte Count; Male; Methysergide; Mice; Pain; Phenylbutazone; Pleurisy; Prednisone; Promethazine; Proteins; Rats; Stimulation, Chemical | 1968 |