methylthiouracil has been researched along with Goiter* in 43 studies
1 review(s) available for methylthiouracil and Goiter
| Article | Year |
|---|---|
THE USE OF THIOURACIL DERIVATIVES DURING PREGNANCY: A REVIEW.
Topics: Basal Metabolism; Female; Fetal Death; Goiter; Humans; Hyperthyroidism; Infant; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Methylthiouracil; Pregnancy; Pregnancy Complications; Propylthiouracil; Research; Thiouracil; Thyroid Function Tests; Thyrotropin; Thyroxine; Toxicology | 1964 |
42 other study(ies) available for methylthiouracil and Goiter
| Article | Year |
|---|---|
Protein kinase C activity in experimentally developed and regressed rat thyroid goitres.
The presence of protein kinase C activity in rat thyroid glands was demonstrated by kinetic studies, using lysine-rich histone as substrate. DE 52 cellulose chromatography resolved thyroidal protein kinase C activity into two peaks, the first eluting at 50 mM and the second at 150 mM salt solution. They contained respectively 40% and 60% of the total activity. In cytosols from experimentally induced goitres, which are hyperplastic tissues, protein kinase C activity rose 3-4-fold compared to control glands. In this tissue, protein kinase C seems to be present in reversibly activated form, since its activity was completely inhibited in the absence of calcium and phospholipids. After removal of growth stimulus, rapid involution of goitres occurred, producing a spectacular decrease in protein kinase C activity. In goitres regressed for 5 days, the level of protein kinase C was lower than in untreated control tissue. The protein kinase C activities in control glands and developed and regressed goitres were 1.88, 5.85 and 0.74 pmoles 32P/mg tissue, respectively. These results clearly demonstrate, for the first time, a direct correlation between the protein kinase C level and the thyroid gland growth activity induced by endogenous stimuli. Topics: Animals; Calcium; Chromatography, DEAE-Cellulose; Diglycerides; Enzyme Activation; Goiter; Male; Methylthiouracil; Phosphatidylserines; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains | 1985 |
[Effect of carbon monoxide on white rats with the goitrogenic reaction].
Topics: Animals; Carbon Monoxide Poisoning; Chronic Disease; Goiter; Iron; Male; Methylthiouracil; Muscles; Oxygen Consumption; Porphyrins; Rats; Reticulocytes | 1975 |
[The thyrotoxic crisis in childhood].
Topics: Child; Chloramphenicol; Female; Goiter; Humans; Hyperthyroidism; Methylthiouracil; Triiodothyronine | 1974 |
[Cytological-histological findings on the thyroid epithelium following antithyroid drugs in the embryological animal experiment].
Topics: Animals; Antithyroid Agents; Epithelium; Female; Goiter; Hydroxypropiophenone; Karyometry; Maternal-Fetal Exchange; Methylthiouracil; Pregnancy; Rats; Thyroid Gland; Thyrotropin; Time Factors | 1973 |
[Non-neoplastic diseases of the thyroid. Analysis of the immediate and long-term results of 938 thyroidectomies].
Topics: Adolescent; Female; Goiter; Hemorrhage; Humans; Hyperthyroidism; Hypoparathyroidism; Hypothyroidism; Iodine; Methylthiouracil; Postoperative Care; Postoperative Complications; Potassium Iodide; Preoperative Care; Propylthiouracil; Thyroid Diseases; Thyroidectomy; Thyroiditis; Time Factors; Vocal Cord Paralysis | 1973 |
Structure of the tubules of glandula submaxillaris after the administration of goitrogens.
Topics: Animals; Aza Compounds; Carbohydrates; Epithelial Cells; Epithelium; Goiter; Histocytochemistry; Male; Methylthiouracil; Proteins; Rats; Staining and Labeling; Submandibular Gland; Sulfur; Thymine; Thyroid Gland | 1972 |
Studies of the goitrogenic and oncogenic effect of methylthiouracil in C3H mice.
Topics: Adenoma; Animals; Antithyroid Agents; Carcinogens; Carcinoma, Hepatocellular; Cysts; Female; Glucose; Goiter; Imidazoles; Kidney Diseases; Lactates; Liver Neoplasms; Male; Methimazole; Methylthiouracil; Mice; Mice, Inbred Strains; Ovarian Cysts; Oxygen Consumption; Thyroid Diseases; Thyroid Gland; Thyroid Neoplasms; Triiodothyronine | 1971 |
[Goitrogenic action of minocycline].
Topics: Adrenal Glands; Amides; Animals; Diet; Female; Goiter; Iodine; Iodine Isotopes; Male; Methylamines; Methylthiouracil; Muscles; Organ Size; Pituitary Gland; Rats; Stimulation, Chemical; Tetracycline; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones; Thyroidectomy; Thyroxine | 1971 |
[Mechanism of the antigoitrogenic effect of iodine and some metal salts during the use of 6-methylthiouracil].
Topics: Cobalt; Copper; Goiter; Iodine; Lead; Manganese; Methylthiouracil; Nickel; Trace Elements; Zinc | 1971 |
The long-term effects of x-radiation on the goitrogenic response of and iodide trapping by the rat thyroid.
Topics: Animals; Goiter; Iodides; Methylthiouracil; Radiation Effects; Rats; Thyroid Gland | 1970 |
Development of goitre after methylthiouracil treatment of mice with hypothalamic lesions.
Topics: Animals; Castration; Electrocoagulation; Female; Goiter; Hypothalamus; Male; Methylthiouracil; Mice; Sex Factors; Stereotaxic Techniques; Thyrotropin | 1969 |
[Parakeratosis in the pig. 4. Parakeratosis induced by methylthiouracil].
Topics: Animals; Body Weight; Bone and Bones; Goiter; Keratosis; Liver; Methylthiouracil; Swine; Swine Diseases; Thyroid Gland; Zinc | 1969 |
[Effect of methylthiouracil on the early course of the postoperative period in patients with nodular toxic goiter].
Topics: Adult; Aged; Cholelithiasis; Goiter; Graves Disease; Humans; Methylthiouracil; Middle Aged; Postoperative Care; Postoperative Complications | 1968 |
[Goiters induced or aggravated by ill chosen prescription of synthetic antithyroids].
Topics: Adolescent; Adult; Antithyroid Agents; Blood Cell Count; Diagnosis, Differential; Diagnostic Errors; Female; Goiter; Heart Auscultation; Humans; Hyperthyroidism; Iodine Radioisotopes; Male; Methylthiouracil; Myxedema; Nervous System Diseases; Neurotic Disorders; Propylthiouracil; Radioisotope Dilution Technique; Thiazoles; Thiouracil; Thiourea; Thyrotropin | 1967 |
Quantitative radiological and histological studies of the thymus in thyroid disease.
Topics: Adult; Aged; Anthropometry; Antithyroid Agents; Autoimmune Diseases; Chronic Disease; Female; Goiter; Humans; Hyperthyroidism; Male; Methylthiouracil; Middle Aged; Thymus Gland; Thyroiditis | 1967 |
Correlation of dose of x-radiation to the rat thyroid gland with degree of subsequent impairment of response to goitrogenic stimulus.
Topics: Animals; Antithyroid Agents; Goiter; Male; Methylthiouracil; Microscopy; Neoplasms, Radiation-Induced; Organ Size; Propylthiouracil; Radiation Effects; Rats; Thyroid Gland; Triazoles | 1967 |
[Various vitamin requirements in patients with endemic goiter].
Topics: Adolescent; Adult; Female; Goiter; Humans; Hyperthyroidism; Male; Methylthiouracil; Middle Aged; Vitamins | 1967 |
EFFECT OF TREATMENT OF THYROTOXICOSIS ON EXOPHTHALMOS.
Topics: Diagnosis; Drug Therapy; Exophthalmos; Goiter; Graves Disease; Humans; Hyperthyroidism; Iodine Isotopes; Methylthiouracil; Thyroid Function Tests; Thyrotoxicosis | 1965 |
Lack of inhibitory or excitatory effects of sex hormones on the development of normal methylthiouracil-induced goiter in the rat.
Topics: Animals; Blood Proteins; Body Weight; Erythrocytes; Estradiol; Goiter; Male; Methyltestosterone; Methylthiouracil; Organ Size; Rats; Seminal Vesicles; Testosterone; Thyroid Gland; Thyroxine | 1965 |
[TREATMENT OF TOXIC GOITERS WITH THE COMBINED USE OF SMALL DOSES OF MERCAZOLYL OR METHYLTHIOURACIL WITH RESERPINE].
Topics: Antithyroid Agents; Goiter; Humans; Methimazole; Methylthiouracil; Reserpine | 1964 |
[ANTITHYROID TREATMENT COMBINED WITH THE ADMINISTRATION OF THYROID HORMONES].
Topics: Drug Therapy; Goiter; Graves Disease; Humans; Hyperthyroidism; Methylthiouracil; Thyroid Hormones; Thyronines | 1964 |
[CHANGES IN THE THYROTROPIC CELLS IN DIFFERENT PATHOLOGICAL AND EXPERIMENTAL STATES].
Topics: Adenoma; Goiter; Graves Disease; Iodine; Methylthiouracil; Pathology; Pharmacology; Pituitary Gland; Rats; Research; Thyroid Neoplasms; Thyrotrophs; Triiodothyronine | 1964 |
[A CASE OF DRUG-INDUCED AGRANULOCYTOSIS].
Topics: Adolescent; Agranulocytosis; Exophthalmos; Goiter; Graves Disease; Hydroxyzine; Methylthiouracil; Toxicology | 1964 |
AUTORADIOGRAPHY OF THE THYROID GLAND.
Topics: Autoradiography; Electrons; Goiter; Hypophysectomy; Iodine Isotopes; Methylthiouracil; Microscopy; Microscopy, Electron; Pharmacology; Pituitary Hormones, Anterior; Rats; Research; Thyroglobulin; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone | 1964 |
[STUDY OF THE SOLUBLE PROTEINS OF THE THYROID GLAND OF PATIENTS TREATED WITH IODO-IODATED SOLUTION AND WITH THIOURACIL DRUGS].
Topics: Autoradiography; Electrophoresis; Goiter; Humans; Hyperthyroidism; Iodates; Iodides; Iodine; Iodine Isotopes; Methylthiouracil; Proteins; Thiouracil; Thyroglobulin; Thyroid Gland | 1964 |
[SOLUBLE THYROID PROTEINS: ELECTROPHORETIC STUDY OF NORMAL AND PATHOLOGICAL THYROID EXTRACTS].
Topics: Electrophoresis; Goiter; Humans; Hyperthyroidism; Iodides; Iodine; Methylthiouracil; Pharmacology; Proteins; Thyroglobulin; Thyroid Gland; Thyroid Hormones | 1964 |
[SELECTION OF A METHOD FOR THE TREATMENT OF TOXIC GOITER IN CHILDREN].
Topics: Adolescent; Antithyroid Agents; Child; Drug Therapy; Goiter; Humans; Hyperthyroidism; Methylthiouracil; Perchlorates; Reserpine; Thyrotoxicosis | 1964 |
[ROLE OF THE I-131 ABSORPTION CURVE OF THE THYROID GLAND IN TOXIC GOITER PATIENTS IN THE EVALUATION OF THE STABILITY OF THERAPEUTIC EFFECTS].
Topics: Goiter; Hyperthyroidism; Iodine Isotopes; Methylthiouracil; Radiotherapy; Thyroid Function Tests; Thyroidectomy | 1964 |
[MODERN THERAPY OF HYPERTHYROIDISM].
Topics: Antithyroid Agents; Exophthalmos; Goiter; Graves Disease; Humans; Hyperthyroidism; Iodine Isotopes; Methylthiouracil; Perchlorates; Radiotherapy; Thiouracil; Thiourea; Thyroidectomy | 1963 |
PATHOLOGY OF FOLLICULAR THYROID ADENOMA REGARDING MALIGNANT AND REGRESSIVE CHANGES.
Topics: Adenoma; Goiter; Histology; Humans; Iodine; Methylthiouracil; Neoplasm Metastasis; Neoplasms; Pathology; Thyroid Neoplasms | 1963 |
[Combined treatment with methylthiouracil and radioactive iodine (I-131) of patients with toxic goiter].
Topics: Combined Modality Therapy; Goiter; Hyperthyroidism; Iodine; Iodine Radioisotopes; Methylthiouracil; Thiouracil; Thyrotoxicosis | 1960 |
[Thiouracil goiter; thyroid size in patients with Graves and Basedow's syndrome treated with methylthiouracil].
Topics: Goiter; Humans; Hyperthyroidism; Methylthiouracil; Syndrome; Thiouracil | 1957 |
Hyperactivity of hypothalamic neurosecretion and coincidental occurrence of thyroid enlargement following administration of methylthiouracil.
Topics: Goiter; Hyperkinesis; Hyperthyroidism; Hypothalamus; Methylthiouracil; Neurosecretion; Pharmaceutical Preparations; Thiouracil | 1957 |
On the inhibitory effect of 3:5-dinitro-1-thyronine on the development of goitre in guinea-pigs treated with methylthiouracil.
Topics: Goiter; Guinea Pigs; Methylthiouracil; Thiouracil; Thyronines; Thyroxine | 1956 |
[The antagonistic effect of iodine compounds and methylthiouracil with special reference to the inhibition of thiouracil-induced goiter].
Topics: Goiter; Iodides; Iodine; Iodine Compounds; Methylthiouracil; Musculoskeletal Physiological Phenomena; Thiouracil; Thyroxine | 1954 |
[The effect of BAL, methionine and cystine on thyroid hyperplasia after short administration of methylthiouracil].
Topics: Cystine; Dimercaprol; Goiter; Hyperplasia; Hypertrophy; Methionine; Methylthiouracil; Pharmaceutical Preparations; Thiouracil; Thyroid Gland; Viscera | 1954 |
[Effect of BAL, methionine and cystine on thyroid hyperplasia after short methylthiouracil administration].
Topics: Cystine; Dimercaprol; Goiter; Hyperplasia; Hypertrophy; Methionine; Methylthiouracil; Thiouracil | 1954 |
[Vitamin E and methylthiouracil goiter].
Topics: Goiter; Methylthiouracil; Thiouracil; Vitamin E | 1953 |
[Surgical results in goiters unsuccessfully treated with methylthiouracil].
Topics: Goiter; Humans; Methylthiouracil | 1951 |
[Effects of methylthiouracil and aminothiazole in preoperative therapy in Basedow's disease and thyreotoxicosis].
Topics: Goiter; Graves Disease; Humans; Methylthiouracil; Sulfanilamide; Sulfanilamides; Sulfonamides; Thiouracil; Thyroid Gland | 1950 |
[Experimental study of the thyroid: effect of tilia leaf extract on the methylthiouracil-induced goiter in the guinea-pig].
Topics: Goiter; Guinea Pigs; Methylthiouracil; Thyroid Gland; Tilia | 1949 |
Antithyroid substances; on the thyroid hyperplasia following the administration of methylthiouracil and some related compounds.
Topics: Goiter; Hyperplasia; Methylthiouracil; Pharmaceutical Preparations; Thiouracil; Thiourea; Thyroid Gland | 1945 |