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methylprednisolone hemisuccinate and Injuries, Spinal Cord

methylprednisolone hemisuccinate has been researched along with Injuries, Spinal Cord in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19907 (13.21)18.7374
1990's14 (26.42)18.2507
2000's14 (26.42)29.6817
2010's15 (28.30)24.3611
2020's3 (5.66)2.80

Authors

AuthorsStudies
Ahmed, EA; Ahmed, MF; Al-Abbadi, HA; Hashem, MA; Helal, IE; Maaty, AI; Mahmoud, YK; Metwally, E1
Bai, Y; Chen, K; Fan, Z; Jiao, K; Li, B; Li, J; Li, M; Liu, C; Wang, H; Wei, X; Wu, J; Yang, H; Zhai, X; Zhang, H; Zhou, T1
Abdullin, TI; Ahmetov, NF; Baltin, ME; Baltina, TV; Kamalov, MI; Kiseleva, EI; Lavrov, IA; Petrova, NV; Sabirova, DE; Sachenkov, OA1
Janzadeh, A; Mojarad, N; Nasirinezhad, F; Yousefifard, M1
Bierbrauer, KS; Caruso, MC; Daugherty, MC; Falcone, RA; Geis, GL; Moody, SM1
Inaba, T; Kitamura, M; Nakayama, M; Nishida, H; Tanaka, H1
Druschel, C; Schaser, KD; Schwab, JM1
Liu, HY; Miao, KN; Qian, YL; Wang, B; Wang, HM; Wang, KF; Zhang, HW; Zhu, ZQ1
Furuya, T; Inada, T; Ito, Y; Kamiya, K; Kato, K; Koda, M; Maki, S; Okawa, A; Ota, M; Sakuma, T; Takahashi, H; Takahashi, K; Yamazaki, M1
Ha, KY; Kim, JW; Kim, SI; Kim, YH; Seo, JY1
Bramanti, P; Galuppo, M; Giacoppo, S; Mazzon, E; Pace, S; Rossi, A; Sautebin, L1
Jo, SH; Kim, WH; Kim, Y; Kweon, OK1
Bilensoy, E; Eroglu, H; Gurcan, O; Gurcay, AG; Karabey-Akyurek, Y; Oner, L; Sargon, MF; Turkoglu, OF; Yabanoglu-Ciftci, S1
Bramanti, P; Giacoppo, S; Libro, R; Mazzon, E1
Ito, Y; Kai, N; Sugimoto, Y; Tanaka, M; Tomioka, M1
Beşalti, O; Calişkan, M; Kaptanoğlu, E; Kilinç, K; Sanli, AM; Sargon, MF; Sekerci, Z; Serbes, G1
Chen, S; Han, H; He, N; Liu, Z; Wang, Z; Xiong, M; Yu, H; Zeng, Y1
Besalti, O; Irak, A; Kilinc, K; Sanli, AM; Sargon, MF; Sekerci, Z; Serbes, G; Turkoglu, E1
Fehlings, MG; Forgione, N; Wilson, JR1
Bracken, MB1
Anders, JJ; Borke, RC; Nash, HH1
Gu, JK; McCutcheon, EP; Pickelsimer, EE; Selassie, AW1
Badhe, P; Sharma, A; Sharma, G; Tiwari, R1
Lammertse, DP1
Ishiguro, N; Kiuchi, K; Matsuyama, Y; Nakashima, S; Yanase, M; Yu, Y1
Balbach, S; Barth, J; Derendorf, H; Madabushi, R; Möllenhoff, G; Möllmann, H; Nagaraja, NV; Schumann, R; Winkler, J1
Ishiguro, N; Kiuchi, K; Matsuyama, Y; Nakashima, S; Yu, Y1
Attar, A; Beskonakli, E; Kaptanoglu, E; Kilinc, K; Okutan, O; Solaroglu, I1
Brines, M; Carelli, S; Cerami, A; Coleman, T; De Biasi, S; Di Giulio, AM; Di Stefano, B; Gorio, A; Madaschi, L1
Shiba, K; Takagishi, K; Tsutsumi, S; Ueta, T; Yamamoto, S1
Bao, F; Hachmeister, JE; Liu, D; Valluru, L1
Braughler, JM; Hall, ED3
Braughler, JM; Hall, ED; Wolf, DL1
Demeny, M; Demopoulos, H; Flamm, E; Naftchi, NE1
Epstein, N; Hood, DC; Ransohoff, J1
Ellis, MF1
Woodhouse, D1
Hou, T; Zhang, J; Zhao, D1
Emery, DG; Gross, GW; Jordan, RS; Lucas, JH; Rosenberg, LJ1
Gerndt, SJ; Micheals, AJ; Papadopoulos, SM; Pawlik, JW; Rodriguez, JL; Taheri, PA; Wahl, WL1
Mewe, P; van Frank, E; Ward, JC1
Kim, YS; Yoon, DH; Young, W1
Blakemore, WF; Jeffery, ND1
Akbiyik, F; Caner, HH; Kaptanoglu, E; Sürücü, HS1
Augustus, L; Li, L; Liu, D1
Baskin, DS; Bracken, MB; Collins, WF; Eisenberg, HM; Flamm, E; Holford, TR; Leo-Summers, L; Maroon, JC; Marshall, LF; Shepard, MJ1
Caiozzo, V; Gardner, VO1
Johnson, LA1
Iizuka, H; Iwasaki, Y; Kadoya, S; Yamamoto, T1

Reviews

6 review(s) available for methylprednisolone hemisuccinate and Injuries, Spinal Cord

ArticleYear
Emerging therapies for acute traumatic spinal cord injury.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Apr-02, Volume: 185, Issue:6

    Topics: ADP Ribose Transferases; Botulinum Toxins; Cell Transplantation; Decompression, Surgical; Hemodynamics; Humans; Hypothermia, Induced; Methylprednisolone Hemisuccinate; Minocycline; Neuroprotective Agents; Riluzole; Spinal Cord Injuries; Treatment Outcome

2013
Steroids for acute spinal cord injury.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Anti-Inflammatory Agents; Humans; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Spinal Cord Injuries

2002
Update on pharmaceutical trials in acute spinal cord injury.
    The journal of spinal cord medicine, 2004, Volume: 27, Issue:4

    Topics: Acute Disease; Clinical Trials as Topic; G(M1) Ganglioside; Humans; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Spinal Cord Injuries

2004
High-dose steroid therapy offers improvement in spinal cord injuries.
    AACN clinical issues in critical care nursing, 1993, Volume: 4, Issue:3

    Topics: Adult; Aged; Humans; Male; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

1993
Spinal cord injury in small animals 2. Current and future options for therapy.
    The Veterinary record, 1999, Aug-14, Volume: 145, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Cats; Dogs; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Spinal Cord Injuries

1999
Steroids after spinal cord injury.
    Lancet (London, England), 1990, Aug-04, Volume: 336, Issue:8710

    Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors

1990

Trials

7 trial(s) available for methylprednisolone hemisuccinate and Injuries, Spinal Cord

ArticleYear
Methylprednisolone sodium succinate reduces spinal cord swelling but does not affect recovery of dogs with surgically treated thoracolumbar intervertebral disk herniation.
    The Japanese journal of veterinary research, 2016, Volume: 64, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Dog Diseases; Dogs; Female; Intervertebral Disc Displacement; Male; Methylprednisolone Hemisuccinate; Postoperative Care; Spinal Cord Injuries

2016
Neuroprotective therapy with granulocyte colony-stimulating factor in acute spinal cord injury: a comparison with high-dose methylprednisolone as a historical control.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015, Volume: 24, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Neuroprotective Agents; Prospective Studies; Recovery of Function; Retrospective Studies; Spinal Cord Injuries; Treatment Outcome; Young Adult

2015
Does high dose methylprednisolone sodium succinate really improve neurological status in patient with acute cervical cord injury?: a prospective study about neurological recovery and early complications.
    Spine, 2009, Sep-15, Volume: 34, Issue:20

    Topics: Acute Disease; Cervical Vertebrae; Cohort Studies; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Neuroprotective Agents; Pneumonia; Postoperative Complications; Prospective Studies; Recovery of Function; Spinal Cord Injuries; Treatment Outcome

2009
[Clinical effect of methylprednisolone sodium succinate and mouse nerve growth factor for injection in treating acute spinal cord injury and cauda equina injury].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2010, Volume: 24, Issue:10

    Topics: Adult; Aged; Cauda Equina; Decompression, Surgical; Female; Fracture Fixation, Internal; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Nerve Growth Factor; Spinal Cord Injuries; Spinal Fractures

2010
Gastrointestinal bleeding in patients with spinal cord trauma. Effects of steroids, cimetidine, and mini-dose heparin.
    Journal of neurosurgery, 1981, Volume: 54, Issue:1

    Topics: Adrenal Cortex Hormones; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Heparin; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

1981
Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study.
    Journal of neurosurgery, 1992, Volume: 76, Issue:1

    Topics: Acute Disease; Double-Blind Method; Follow-Up Studies; Humans; Methylprednisolone Hemisuccinate; Naloxone; Psychomotor Performance; Spinal Cord Injuries; Survival Rate; Time Factors

1992
Steroids after spinal cord injury.
    Lancet (London, England), 1990, Aug-04, Volume: 336, Issue:8710

    Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors

1990

Other Studies

41 other study(ies) available for methylprednisolone hemisuccinate and Injuries, Spinal Cord

ArticleYear
Selective Calpain Inhibition Improves Functional and Histopathological Outcomes in a Canine Spinal Cord Injury Model.
    International journal of molecular sciences, 2022, Oct-04, Volume: 23, Issue:19

    Topics: Acrylates; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Calpain; Dogs; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries

2022
Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 360

    Topics: Animals; beta-Cyclodextrins; Cyclodextrins; Delayed-Action Preparations; Metal-Organic Frameworks; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries

2023
Comparison of systemic and localized carrier-mediated delivery of methylprednisolone succinate for treatment of acute spinal cord injury.
    Experimental brain research, 2021, Volume: 239, Issue:2

    Topics: Animals; Chromatography, Liquid; Methylprednisolone Hemisuccinate; Rats; Spinal Cord; Spinal Cord Injuries; Tandem Mass Spectrometry

2021
The role of low level laser therapy on neuropathic pain relief and interleukin-6 expression following spinal cord injury: An experimental study.
    Journal of chemical neuroanatomy, 2018, Volume: 87

    Topics: Animals; Disease Models, Animal; Interleukin-6; Low-Level Light Therapy; Male; Methylprednisolone Hemisuccinate; Neuralgia; Neuroprotective Agents; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries

2018
Lessons learned from administration of high-dose methylprednisolone sodium succinate for acute pediatric spinal cord injuries.
    Journal of neurosurgery. Pediatrics, 2017, Volume: 20, Issue:6

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Hyperglycemia; Infant; Infant, Newborn; Male; Methylprednisolone Hemisuccinate; Nausea; Neuroprotective Agents; Retrospective Studies; Spinal Cord Injuries

2017
Current practice of methylprednisolone administration for acute spinal cord injury in Germany: a national survey.
    Spine, 2013, May-15, Volume: 38, Issue:11

    Topics: Acute Disease; Germany; Health Care Surveys; Humans; Methylprednisolone Hemisuccinate; Neuroprotective Agents; North America; Spinal Cord Injuries; Surveys and Questionnaires

2013
[Effects of intrathecal injection of methylprednisolone sodium succinate in acute spinal cord injury rabbits].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2013, May-01, Volume: 51, Issue:5

    Topics: Acute Disease; Analysis of Variance; Animals; Disease Models, Animal; Injections, Spinal; Male; Methylprednisolone Hemisuccinate; Rabbits; Recovery of Function; Spinal Cord Injuries

2013
Effects of Therapeutic Hypothermia on Apoptosis and Autophagy After Spinal Cord Injury in Rats.
    Spine, 2015, Jun-15, Volume: 40, Issue:12

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Behavior, Animal; Blotting, Western; Cytoprotection; Disease Models, Animal; Hypothermia, Induced; Immunohistochemistry; Male; Methylprednisolone Hemisuccinate; Microscopy, Electron, Transmission; Motor Activity; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors

2015
Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids.
    Pharmacological research, 2015, Volume: 99

    Topics: Animals; Apoptosis; Cell Line; Dexamethasone; Disease Models, Animal; Glucocorticoids; Inflammation; Male; MAP Kinase Signaling System; Methylprednisolone Hemisuccinate; Mice; Mometasone Furoate; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Spinal Cord; Spinal Cord Injuries

2015
Antioxidant and anti-inflammatory effects of intravenously injected adipose derived mesenchymal stem cells in dogs with acute spinal cord injury.
    Stem cell research & therapy, 2015, Nov-26, Volume: 6

    Topics: Acute Disease; Adipose Tissue; Animals; Anti-Inflammatory Agents; Antioxidants; Dogs; Glucocorticoids; Injections, Intravenous; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

2015
Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model.
    Pharmaceutical development and technology, 2017, Volume: 22, Issue:8

    Topics: Animals; Drug Delivery Systems; Methylprednisolone Hemisuccinate; Nanoparticles; Neuroprotective Agents; Rats; Spinal Cord Injuries

2017
Is the Wnt/β-catenin pathway involved in the anti-inflammatory activity of glucocorticoids in spinal cord injury?
    Neuroreport, 2016, Sep-28, Volume: 27, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Catenins; Disease Models, Animal; Glucocorticoids; Interleukin-1beta; Male; Methylprednisolone Hemisuccinate; Mice; Mometasone Furoate; Myelitis; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Wnt Signaling Pathway

2016
Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:12

    Topics: Animals; Axons; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Lipid Peroxidation; Methylprednisolone Hemisuccinate; Microscopy, Electron, Transmission; Mitochondria; Neuroprotective Agents; Peroxidase; Rats; Rats, Wistar; Spinal Cord Injuries

2010
Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.
    Turkish neurosurgery, 2012, Volume: 22, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Disease Models, Animal; Female; Lipid Peroxidation; Malondialdehyde; Methylprednisolone Hemisuccinate; Mitochondria; Nerve Fibers, Myelinated; Neuroprotective Agents; Rats; Rats, Wistar; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2012
Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-15, Volume: 22, Issue:16

    Topics: Animals; Axons; Behavior, Animal; Brain Tissue Transplantation; Cell Count; Disease Models, Animal; Fluorescent Dyes; Methylprednisolone Hemisuccinate; Motor Skills; Nerve Regeneration; Neurons; Neuroprotective Agents; Olfactory Bulb; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Stilbamidines; Treatment Outcome

2002
Acute traumatic spinal cord injury, 1993-2000A population-based assessment of methylprednisolone administration and hospitalization.
    The Journal of trauma, 2004, Volume: 56, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Dose-Response Relationship, Drug; Drug Utilization; Emergency Service, Hospital; Female; Health Care Surveys; Hospital Charges; Hospitalization; Humans; Length of Stay; Logistic Models; Male; Methylprednisolone Hemisuccinate; Middle Aged; Multivariate Analysis; Neuroprotective Agents; Population Surveillance; Practice Patterns, Physicians'; South Carolina; Spinal Cord Injuries; Surveys and Questionnaires; Trauma Centers

2004
Comparison of methylprednisolone with dexamethasone in treatment of acute spinal injury in rats.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:5

    Topics: Animals; Dexamethasone; Edema; Female; Glucocorticoids; Hypoxia; Male; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Time Factors

2004
Effects of MPSS and a potent iNOS inhibitor on traumatic spinal cord injury.
    Neuroreport, 2004, Sep-15, Volume: 15, Issue:13

    Topics: Amidines; Animals; Cell Count; Cell Death; Drug Interactions; Gene Expression Regulation; Heterocyclic Compounds, 2-Ring; Immunohistochemistry; In Situ Nick-End Labeling; Male; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord Injuries; Time Factors; Urinary Bladder, Neurogenic

2004
Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.
    International journal of clinical pharmacology and therapeutics, 2004, Volume: 42, Issue:9

    Topics: Accidents; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Area Under Curve; Chromatography, High Pressure Liquid; Female; Humans; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Saliva; Spinal Cord Injuries

2004
Suppression of GDNF production by MPSS treatment following spinal cord injury in the rat.
    Neuroreport, 2004, Oct-25, Volume: 15, Issue:15

    Topics: Animals; Blotting, Northern; CD11b Antigen; Cell Count; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Male; Methylprednisolone Hemisuccinate; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord Injuries; Time Factors

2004
Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats.
    Surgical neurology, 2005, Volume: 64 Suppl 2

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Female; Magnesium Sulfate; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord Injuries

2005
Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-08, Volume: 102, Issue:45

    Topics: Animals; Drug Interactions; Erythropoietin; Interleukin-6; Methylprednisolone Hemisuccinate; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2005
Effects of the Second National Acute Spinal Cord Injury Study of high-dose methylprednisolone therapy on acute cervical spinal cord injury-results in spinal injuries center.
    Spine, 2006, Dec-15, Volume: 31, Issue:26

    Topics: Acute Disease; Cervical Vertebrae; Female; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Neuroprotective Agents; Paralysis; Recovery of Function; Retrospective Studies; Spinal Cord Injuries

2006
Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: a comparison with methylprednisolone.
    Journal of neurotrauma, 2006, Volume: 23, Issue:12

    Topics: Animals; Apoptosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Free Radical Scavengers; Injections, Spinal; Male; Metalloporphyrins; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2006
Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function.
    Journal of neurosurgery, 1982, Volume: 56, Issue:6

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Membrane Potentials; Methylprednisolone; Methylprednisolone Hemisuccinate; Motor Neurons; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Spinal Cord Injuries

1982
Effects of intravenous methylprednisolone on spinal cord lipid peroxidation and Na+ + K+)-ATPase activity. Dose-response analysis during 1st hour after contusion injury in the cat.
    Journal of neurosurgery, 1982, Volume: 57, Issue:2

    Topics: Animals; Blood Pressure; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Female; Free Radicals; Injections, Intravenous; Lipid Peroxides; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Time Factors

1982
Uptake and elimination of methylprednisolone from contused cat spinal cord following intravenous injection of the sodium succinate ester.
    Journal of neurosurgery, 1983, Volume: 58, Issue:4

    Topics: Animals; Cats; Contusions; Female; Injections, Intravenous; Kinetics; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries

1983
Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose-response and time-action analysis.
    Journal of neurosurgery, 1984, Volume: 61, Issue:1

    Topics: Animals; Cats; Female; Ischemia; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries

1984
Spinal cord regeneration.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Action Potentials; Adenylyl Cyclases; Aminocaproic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Cats; Dopamine beta-Hydroxylase; Endothelium; Methylprednisolone Hemisuccinate; Microscopy, Electron, Scanning; Monoamine Oxidase; Nerve Regeneration; Spinal Cord Injuries

1980
High-dose intravenous infusions of Solu-Medrol for use in acute spinal cord injuries.
    The Medical journal of Australia, 1993, Jul-05, Volume: 159, Issue:1

    Topics: Acute Disease; Drug Approval; Humans; Infusions, Intravenous; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

1993
Drugs for acute spinal cord injury.
    The Medical letter on drugs and therapeutics, 1993, Aug-06, Volume: 35, Issue:902

    Topics: Drug Administration Schedule; G(M1) Ganglioside; Humans; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

1993
[Changes of NGF in injured spinal cord following treatment with a single large dose of methylprednisolone sodium succinate].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1995, Volume: 33, Issue:12

    Topics: Animals; Female; Methylprednisolone Hemisuccinate; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

1995
Effects of methylprednisolone on lesioned and uninjured mammalian spinal neurons: viability, ultrastructure, and network electrophysiology.
    Journal of neurotrauma, 1996, Volume: 13, Issue:8

    Topics: Animals; Cell Survival; Cells, Cultured; Dendrites; Dose-Response Relationship, Drug; Laser Therapy; Membrane Potentials; Methylprednisolone Hemisuccinate; Mice; Microscopy, Electron; Neurons; Regression Analysis; Spinal Cord; Spinal Cord Injuries; Time Factors

1996
Consequences of high-dose steroid therapy for acute spinal cord injury.
    The Journal of trauma, 1997, Volume: 42, Issue:2

    Topics: Accidents, Traffic; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Multiple Trauma; Retrospective Studies; Spinal Cord Injuries; Treatment Outcome; Wounds, Nonpenetrating

1997
[Fracture of the odontoid process in primary myelopathy. Report of a case].
    Unfallchirurgie, 1998, Volume: 24, Issue:1

    Topics: Accidents; Administration, Topical; Anti-Inflammatory Agents; Cervical Atlas; Fractures, Bone; Glucocorticoids; Humans; Male; Methylprednisolone Hemisuccinate; Middle Aged; Nervous System Diseases; Odontoid Process; Quadriplegia; Spinal Cord Injuries; Tomography, X-Ray Computed

1998
Therapeutic time window for methylprednisolone in spinal cord injured rat.
    Yonsei medical journal, 1999, Volume: 40, Issue:4

    Topics: Animals; Drug Administration Schedule; Male; Methylprednisolone Hemisuccinate; Neuroprotective Agents; Rats; Rats, Long-Evans; Spinal Cord; Spinal Cord Injuries

1999
Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury.
    Journal of neurosurgery, 1999, Volume: 91, Issue:2 Suppl

    Topics: Analysis of Variance; Animals; Antioxidants; Lipid Peroxidation; Male; Methylprednisolone Hemisuccinate; Mexiletine; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

1999
Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.
    Journal of neurochemistry, 2001, Volume: 77, Issue:4

    Topics: Animals; Cell Death; Dinoprost; Hydroxyl Radical; Injections, Spinal; Male; Malondialdehyde; Methylprednisolone Hemisuccinate; Microdialysis; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors

2001
Medical management of spinal cord injury.
    The Western journal of medicine, 1991, Volume: 155, Issue:2

    Topics: Calpain; Humans; Ischemia; Methylprednisolone Hemisuccinate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries

1991
Management of acute spinal trauma.
    The Veterinary record, 1991, Jan-26, Volume: 128, Issue:4

    Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Methylprednisolone Hemisuccinate; Spinal Cord Injuries

1991
Morphometric assessment of drug effects in experimental spinal cord injury.
    Journal of neurosurgery, 1986, Volume: 65, Issue:1

    Topics: Animals; Axons; Leucine; Leupeptins; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Spinal Cord Injuries

1986