methylprednisolone and Osteonecrosis

methylprednisolone has been researched along with Osteonecrosis in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199013 (13.00)18.7374
1990's11 (11.00)18.2507
2000's31 (31.00)29.6817
2010's37 (37.00)24.3611
2020's8 (8.00)2.80

Authors

AuthorsStudies
Jiang, Y; Lin, L; Liu, K; Yu, Y; Zhou, Z2
Hu, Y; Lin, H; Lu, C1
Hao, Y; Li, H; Lu, C; Wang, X; Xu, K; Xu, P; Zhang, Y; Zhu, B1
Dong, R; Fang, L; Ge, Q; Jin, H; Shi, Z; Tong, P; Wang, P; Xia, C; Xu, H; Xu, R; Zhang, P; Zou, Z1
Chen, YY; Sun, SW; Tian, YY; Wu, XS; Yang, CB; Zhao, P1
Bao, PF; Chen, Q; Dai, JJ; Han, YY; Hu, M; Kuang, DX; Li, YJ; Liu, BL; Ma, DP; Ma, TK; Ma, ZX; Shi, H; Wang, WG; Wang, WL; Wu, XF; Xia, LB; Ye, ZN; Yu, CT; Zhang, RP1
Jin, W; Lu, M; Yang, X1
Akutsu, Y; Mori, M; Segawa, Y; Shimbo, A; Shimizu, M; Yamazaki, S1
Aurer, I; Basic-Kinda, S; Dotlic, S; Durakovic, N; Hude, I; Karlak, I; Livaja Radman, I; Lubina, ZI; Peric, Z1
Ichiseki, T; Kaneuji, A; Kawahara, N; Shimazaki, M; Tsuchiya, M; Ueda, S; Ueda, Y1
Fan, L; Ge, Z; Ji, W; Li, J; Li, M; Wang, K; Yuan, N1
Gao, Y; Pan, C; Shan, H; Wang, N; Yu, X; Zhou, L; Zhou, Z1
Cheng, XY; Lee, KM; Leung, KS; Qin, L; Qu, S; Sheng, CJ; Sheng, H; Zhang, G1
Gao, C; Ji, C; Li, H; Qiu, G; Weng, X; Wu, Z1
Chen, Y; Feng, JQ; Fong, DT; He, YX; Huang, L; Lei, M; Liu, Y; Liu, Z; Man, CW; Peng, J; Qin, L; Wang, DP; Wang, XL; Xiao, DM; Xie, XH; Zhang, G; Zheng, LZ1
Chen, W; Jiang, Y; Li, P; Lin, N; Lu, C; Xu, Y; Zhang, H; Zhang, Y; Zhu, B1
Ikemura, S; Iwamoto, Y; Iwasaki, K; Motomura, G; Yamaguchi, R; Yamamoto, T; Zhao, G3
Fujioka, M; Hayashi, S; Ikegami, A; Ikoma, K; Ishida, M; Kubo, T; Kuribayashi, M; Mazda, O; Saito, M; Ueshima, K1
Göksel, F; Hatay Gölge, U; Kaymaz, B; Kömürcü, E; Nusran, G; Oktay, M1
Dilisio, MF1
Bi, W; Dang, X; Liu, R; Shi, Z; Song, Q; Wang, K; Zhang, C1
Dang, X; Fan, L; Li, J; Wang, K; Yu, Z1
Fan, LH; Shi, ZB; Sun, S; Tian, L; Wang, KZ; Zhang, W; Zhou, DS1
Fujioka, M; Fujiwara, H; Hayashi, S; Ikegami, A; Ikoma, K; Ishida, M; Kubo, T; Mazda, O; Saito, M; Ueshima, K1
Lu, WW; Pan, H; Peng, S; Wang, L; Zhang, L; Zhao, X1
Feng, X; Gao, Y; He, Y; Shao, Z; Wang, H; Wu, X; Yang, C; Yang, S; Ye, Z1
Huang, YX; Tao, JG; Zhao, HX1
Fan, L; Ge, Z; Li, J; Wang, K1
Ed AlTayeb Mussa, M; Eh Samir Ansara, S; El Gamal, TA; El-Bakoury, A; Er Ahmed Sweed, T; Hawkins, A1
Nakamura, N; Nishii, T; Sakai, T; Sugano, N; Takao, M; Yoshikawa, H1
Hernigou, P; Li, ZR; Liu, ZH; Wei, HY; Zhang, NF1
Duan, D; Jiang, S; Liu, X; Wang, J; Wu, X; Yang, C; Yang, S; Zhang, Y1
Asada, A; Iwaki, H; Iwakiri, K; Kaneshiro, Y; Kobayashi, A; Masada, T; Oda, Y; Takaoka, K1
Irisa, T; Iwamoto, Y; Miyanishi, K; Motomura, G; Nishida, K; Yamamoto, T1
Hirota, Y; Iwamoto, Y; Kondo, K; Miyanishi, K; Motomura, G; Yamamoto, T1
Büyükavci, M; Eren, S; Karakelleoğlu, C; Orbak, Z; Sahin, A; Yildirim, ZK1
Griffith, JF; Leung, KS; Qin, L; Sheng, H; Wang, YX; Yeung, DK; Zhang, G1
Altavilla, D; Armbruster, MA; Bitto, A; Burnett, B; Di Stefano, V; Levy, R; Marini, H; Minutoli, L; Polito, F; Squadrito, F1
Azuma, T; Kadoya, Y; Kaneshiro, Y; Kim, M; Masada, T; Oda, Y; Takaoka, K; Tokuhara, Y; Wakitani, S1
Shepard, G; Sinclair, V1
Arai, Y; Fujioka, M; Goto, T; Ishida, M; Kubo, T; Kuribayashi, M; Takahashi, KA1
Gao, H; Kang, P; Pei, F; Shen, B; Yang, J; Zhou, Z1
Balal, M; Binokay, F; Demir, E; Erken, U; Kurt, C; Paydas, S; Sertdemir, Y; Sikgenc, MM1
Li, KH; Lu, BB1
Ikegami, H; Nakamura, T; Obara, Y; Sato, K; Toyama, Y; Watanabe, R1
Chan, WP1
Ding, S; Fang, HS; Peng, H; Wang, Z; Zhou, JL1
He, YX; Liu, Z; Qin, L; Sheng, H; Wang, XL; Xie, XH; Zhang, G1
Duan, D; Liu, X; Meng, C; Wang, H; Wu, X; Xu, W; Yang, S1
Chen, GH; Fu, BS; He, JW; Jiang, N; Li, H; Wang, GS; Wang, GY; Wang, K; Yang, Y; Zhang, J2
Cheng, TS; Feng, Y; Li, GY; Yin, JM; Zhang, CQ1
Bünger, CE; Bünger, MH; Drescher, WR; Hansen, ES; Weigert, KP1
Rüther, W; Steinhagen, J1
Ichiseki, T; Kaneuji, A; Katsuda, S; Matsumoto, T; Nishino, M1
Iwamoto, Y; Jingushi, S; Miyanishi, K; Motomura, G; Yamamoto, T1
Ichiseki, T; Kaneuji, A; Katsuda, S; Matsumoto, T; Sugimori, T; Ueda, Y1
Chen, JY; Chen, RC; Liang, BL; Liu, QY; Shen, J; Zeng, QS; Zhong, NS1
Ahuja, AT; Antonio, GE; Chan, KM; Cheung, AY; Chiu, KH; Griffith, JF; Hui, DS; Joynt, GM; Kumta, SM; Leung, PC; Wong, JK; Wu, AK1
Horiuchi, T; Koarada, S; Murai, K; Nagasawa, K; Ohta, A; Tada, Y; Tsukamoto, H; Ueda, A; Yoshizawa, S1
Fujioka, M; Hirata, T; Kabata, T; Kobayashi, M; Kubo, T; Matsumoto, T; Takahashi, KA; Tomita, K; Yagishita, S1
Chan, CW; Cheung, WH; Chiu, KH; Griffith, J; Leung, KS; Qin, L; Sheng, H; Yeung, HY; Yeung, KW; Zhang, G1
Ce, P; Coban, P; Gedizlioglu, M; Gelal, F; Ozbek, G1
Iwamoto, Y; Miyanishi, K; Motomura, G; Nishida, K; Sueishi, K; Yamamoto, T1
Dorey, FJ; Elsissy, P; Kobashigawa, JA; Lieberman, JR; Roth, KM1
Asada, T; Iida, H; Kushida, T; Matsuya, H; Umeda, M; Wada, T1
Iwamoto, Y; Jingushi, S; Motomura, G; Nishida, K; Yamamoto, T1
Chan, C; Cheung, W; Griffith, J; Leung, K; Qin, L; Sheng, H; Yeung, H; Yeung, K; Zhang, G1
Duan, D; Wang, J; Wu, X; Yang, S; Zhang, Y1
Surat, A1
Bonomini, V; Di Felice, A; Feletti, C; Scolari, MP1
Burt, RW; Matthews, TJ1
Dumler, F; Levin, NW; Preuss, LE; Szego, G; Vulpetti, AT1
Auquier, L; Barres, D; Durigon, M; Le Parc, JM; Mignot, J; Paolaggi, F; Paolaggi, JB1
Auquier, L; Barres, D; Durigon, M; Le Parc, JM; Mignot, J; Paolaggi, JB1
Hirano, K; Sueishi, K; Sugioka, Y; Tsutsui, H; Yamamoto, T1
Ambrosone, L; Di Palma, G; Mallozzi, M; Migliaresi, S; Picillo, U; Tesone, ER; Tirri, G1
Chapple, M; Gordon-Smith, EC; Hows, JM; Marsh, JC; Zomas, A1
Dawood, S; Govender, S; Haffejee, AA; Naicker, S; Naiker, IP; Seedat, YK1
Harada, Y; Iida, S; Ikenoue, S; Kashiwabara, H; Moriya, H; Saisu, T; Sakamoto, K; Sakamoto, M; Yamada, K; Yokoyama, T1
Irisa, T; Sueishi, K; Sugioka, Y; Yamamoto, T1
Le Parc, JM; Paolaggi, JB1
Connell, DG; Gagnon, F; Nance, P; Wing, PC1
Balian, G; Cui, Q; Wang, GJ1
Gilkeson, GS; Korompilias, AV; Seaber, AV; Urbaniak, JR1
Irisa, T; Iwamoto, Y; Jingushi, S; Miyanishi, K; Noguchi, Y; Yamamoto, T; Yamashita, A1
Cleary, JD; Clinkscales, A1
Banowsky, LH; Bergfeld, JA; Braun, WE; Straffon, RA; Susan, LP1
Curtiss, PH; Fox, OD; Gold, EW; Weissfeld, S1
González, M; Jacobelli, S; Leissner, M; Massardo, L; Rivero, S; Villarroel, L1
Matsui, M; Ohzono, K; Ono, K; Saito, M; Saito, S; Sugano, N; Takaoka, K1
Mack, GR; O'Brien, TJ1
Ditzian-Kadanoff, R; Ellman, MH1
Jones, JG1
Bacon, PA; Berry, H; Hazleman, BL; Shipley, ME; Sturrock, RD; Swinson, DR; Williams, IA1
Jamieson, T1
Gosling, DC; Hanby, AM; MacLeod, M; Sampson, WF; Slapak, M1

Reviews

2 review(s) available for methylprednisolone and Osteonecrosis

ArticleYear
[Animal models for steroid-induced osteonecrosis].
    Clinical calcium, 2007, Volume: 17, Issue:6

    Topics: Animals; Anticholesteremic Agents; Anticoagulants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans; Hyperlipidemias; Methylprednisolone; Osteonecrosis; Probucol; Rabbits; Thrombocytopenia; Warfarin

2007
How safe is it? High dose intravenous methylprednisolone.
    IMJ. Illinois medical journal, 1987, Volume: 172, Issue:6

    Topics: Anaphylaxis; Blood Pressure; Death, Sudden; Humans; Infusions, Intravenous; Methylprednisolone; Osteonecrosis; Vascular Resistance

1987

Trials

4 trial(s) available for methylprednisolone and Osteonecrosis

ArticleYear
Late side effects of high-dose steroid therapy on skeletal system in children with idiopathic thrombocytopenic purpura.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:10

    Topics: Adolescent; Adrenal Cortex Hormones; Biomarkers; Bone and Bones; Bone Density; Case-Control Studies; Child; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Purpura, Thrombocytopenic, Idiopathic

2008
Avascular necrosis of the bones: an overlooked complication of pulse steroid treatment of multiple sclerosis.
    European journal of neurology, 2006, Volume: 13, Issue:8

    Topics: Adult; Body Mass Index; Cholesterol; Cohort Studies; Female; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Multiple Sclerosis; Osteonecrosis; Treatment Outcome

2006
Risk of avascular necrosis following short term megadose methylprednisolone treatment.
    Spinal cord, 1998, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Female; Femur Head Necrosis; Humans; Humerus; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Prospective Studies; Risk Assessment; Spinal Cord Injuries

1998
Pulsed methylprednisolone in active early rheumatoid disease: a dose-ranging study.
    British journal of rheumatology, 1988, Volume: 27, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infusions, Intravenous; Methylprednisolone; Middle Aged; Osteonecrosis; Random Allocation; Time Factors

1988

Other Studies

94 other study(ies) available for methylprednisolone and Osteonecrosis

ArticleYear
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
    International journal of molecular sciences, 2022, Sep-24, Volume: 23, Issue:19

    Topics: Apoptosis; Chondrocytes; Collagen Type X; Core Binding Factor Alpha 1 Subunit; Down-Regulation; Femur Head; Glucocorticoids; Humans; Hypertrophy; Luciferases; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Methylprednisolone; MicroRNAs; Osteonecrosis; Steroids

2022
Concurrence of osteonecrosis and steroid myopathy secondary to oral steroid therapy in a patient with ABCB1 gene polymorphisms: A case report.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: ATP Binding Cassette Transporter, Subfamily B; Female; Glucocorticoids; Humans; Hydroxybutyrate Dehydrogenase; Lactate Dehydrogenases; Methylprednisolone; Muscular Diseases; Osteonecrosis; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Steroids

2022
Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor.
    Cells, 2022, 12-07, Volume: 11, Issue:24

    Topics: Animals; Cartilage; Chickens; Femur Head; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methylprednisolone; Osteonecrosis; Receptors, Glucocorticoid; Simvastatin

2022
Proanthocyanidins Inhibit Osteoblast Apoptosis via the PI3K/AKT/Bcl-xL Pathway in the Treatment of Steroid-Induced Osteonecrosis of the Femoral Head in Rats.
    Nutrients, 2023, Apr-18, Volume: 15, Issue:8

    Topics: Animals; Apoptosis; Femur Head; Humans; Methylprednisolone; Osteoblasts; Osteonecrosis; Phosphatidylinositol 3-Kinases; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Rats

2023
Yougui pills exert osteoprotective effects on rabbit steroid-related osteonecrosis of the femoral head by activating β-catenin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 120

    Topics: Animals; beta Catenin; Cell Line; Drugs, Chinese Herbal; Femur Head Necrosis; Gene Expression Regulation; Glucocorticoids; Lipopolysaccharides; Male; Methylprednisolone; Mice; Osteogenesis; Osteonecrosis; Rabbits; Random Allocation

2019
Evaluation of Femoral Head Perfusion by Contrast-Enhanced Ultrasound in a Rabbit Model of Steroid-Induced Osteonecrosis.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2020, Volume: 39, Issue:5

    Topics: Animals; Contrast Media; Disease Models, Animal; Feasibility Studies; Female; Femur Head; Image Enhancement; Male; Methylprednisolone; Microvessels; Osteonecrosis; Rabbits; Reproducibility of Results; Ultrasonography

2020
A tree shrew model for steroid-associated osteonecrosis.
    Zoological research, 2020, Sep-18, Volume: 41, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Disease Models, Animal; Glucocorticoids; Lipopolysaccharides; Methylprednisolone; Osteonecrosis; Tupaiidae

2020
Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus: A case report.
    Medicine, 2021, Jan-15, Volume: 100, Issue:2

    Topics: Adolescent; Bone Density Conservation Agents; Calcitriol; Cyclophosphamide; Dipyridamole; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methylprednisolone; Osteonecrosis; Platelet Aggregation Inhibitors

2021
Childhood-onset systemic lupus erythematosus with trisomy X and the increased risk for bone complications: a case report.
    Pediatric rheumatology online journal, 2021, Feb-23, Volume: 19, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Bone Marrow Examination; Chromosomes, Human, X; Cyclophosphamide; Factor VIII; Female; Humans; Lupus Erythematosus, Systemic; Medication Therapy Management; Methylprednisolone; Mycophenolic Acid; Osteonecrosis; Osteoporosis; Pancytopenia; Severity of Illness Index; Sex Chromosome Aberrations; Sex Chromosome Disorders of Sex Development; Thrombosis; Trisomy

2021
High incidence of aseptic hip necrosis in Hodgkin lymphoma patients treated with escalated BEACOPP receiving methylprednisolone.
    Internal medicine journal, 2018, Volume: 48, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cross-Sectional Studies; Cyclophosphamide; Doxorubicin; Etoposide; Female; Glucocorticoids; Hodgkin Disease; Humans; Incidence; Male; Methylprednisolone; Osteonecrosis; Pelvic Bones; Prednisone; Procarbazine; Treatment Outcome; Vincristine; Young Adult

2018
Mitochondrial stress and redox failure in steroid-associated osteonecrosis.
    International journal of medical sciences, 2018, Volume: 15, Issue:3

    Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Humans; Methylprednisolone; Mitochondria; Osteonecrosis; Oxidation-Reduction; Rabbits; Steroids; Superoxide Dismutase

2018
BADGE, a synthetic antagonist for PPARγ, prevents steroid-related osteonecrosis in a rabbit model.
    BMC musculoskeletal disorders, 2018, Apr-27, Volume: 19, Issue:1

    Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Epoxy Compounds; Male; Methylprednisolone; Osteogenesis; Osteonecrosis; PPAR gamma; Rabbits; Random Allocation; Steroids

2018
A high-fat diet aggravates osteonecrosis through a macrophage-derived IL-6 pathway.
    International immunology, 2019, 03-28, Volume: 31, Issue:4

    Topics: Animals; Cell Differentiation; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Macrophages; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Osteogenesis; Osteonecrosis; Signal Transduction

2019
Pathomorphological changes of bone marrow adipocytes in process of steroid-associated osteonecrosis.
    International journal of clinical and experimental pathology, 2013, Volume: 6, Issue:6

    Topics: Adipocytes; Animals; Bone Marrow; Cell Size; Disease Models, Animal; Femur; Hypertrophy; Lipopolysaccharides; Methylprednisolone; Osteonecrosis; Rabbits; Time Factors

2013
Elevated level of membrane microparticles in the disease of steroid-induced vascular osteonecrosis.
    The Journal of craniofacial surgery, 2013, Volume: 24, Issue:4

    Topics: Animals; Cell-Derived Microparticles; Disease Models, Animal; Female; Femur Head Necrosis; Flow Cytometry; Injections, Intramuscular; Male; Methylprednisolone; Osteonecrosis; Rabbits

2013
Steroid-associated hip joint collapse in bipedal emus.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Disease Models, Animal; Dromaiidae; Femur; Hip Joint; Humans; Lipid Metabolism; Lipopolysaccharides; Magnetic Resonance Imaging; Methylprednisolone; Microscopy, Electron, Scanning; Neutrophils; Osteonecrosis; X-Ray Microtomography

2013
Pravastatin prevents steroid-induced osteonecrosis in rats by suppressing PPARγ expression and activating Wnt signaling pathway.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:3

    Topics: Adipogenesis; Adipose Tissue; Adrenal Cortex Hormones; Animals; beta Catenin; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Femur Head; Femur Head Necrosis; Fibrinolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids; Low Density Lipoprotein Receptor-Related Protein-5; Male; Methylprednisolone; Neovascularization, Physiologic; Osteogenesis; Osteonecrosis; PPAR gamma; Pravastatin; Rats; Rats, Wistar; Wnt Signaling Pathway; Wnt3A Protein

2014
Cytochrome P4503A activity affects the gender difference in the development of steroid-induced osteonecrosis in rabbits.
    International journal of experimental pathology, 2014, Volume: 95, Issue:2

    Topics: Animals; Cytochrome P-450 CYP3A; Female; Femur; Humerus; Male; Methylprednisolone; Osteonecrosis; Rabbits; Sex Characteristics

2014
Evaluation of femoral perfusion in a rabbit model of steroid-induced osteonecrosis by dynamic contrast-enhanced MRI with a high magnetic field MRI system.
    Journal of magnetic resonance imaging : JMRI, 2015, Volume: 41, Issue:4

    Topics: Algorithms; Animals; Blood Flow Velocity; Contrast Media; Femoral Artery; Image Enhancement; Image Interpretation, Computer-Assisted; Magnetic Resonance Angiography; Male; Methylprednisolone; Osteonecrosis; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Steroids

2015
Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:2

    Topics: Animals; Disease Models, Animal; Femur Head; Glucocorticoids; Glutathione; Malondialdehyde; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome; Ubiquinone; Vitamins

2014
Osteonecrosis following short-term, low-dose oral corticosteroids: a population-based study of 24 million patients.
    Orthopedics, 2014, Volume: 37, Issue:7

    Topics: Administration, Oral; Databases, Factual; Electronic Health Records; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Osteonecrosis; Software; United States

2014
Beneficial effect of grape seed proanthocyanidin extract in rabbits with steroid-induced osteonecrosis via protecting against oxidative stress and apoptosis.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2015, Volume: 20, Issue:1

    Topics: Animals; Apoptosis; Disease Models, Animal; Glucocorticoids; Grape Seed Extract; Male; Methylprednisolone; Osteonecrosis; Oxidative Stress; Proanthocyanidins; Rabbits

2015
The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:2

    Topics: Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Deferoxamine; Disease Models, Animal; Femur Head; Glucocorticoids; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Methylprednisolone; Neovascularization, Physiologic; Osteocalcin; Osteonecrosis; Rabbits; Siderophores; Vascular Endothelial Growth Factor A; von Willebrand Factor; X-Ray Microtomography

2015
Association of toll-like receptor 4 signaling pathway with steroid-induced femoral head osteonecrosis in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014, Volume: 34, Issue:5

    Topics: Acid Phosphatase; Animals; Blotting, Western; Chemokine CCL2; Femur Head; Gene Expression; Immunohistochemistry; Isoenzymes; Male; Methylprednisolone; Myeloid Differentiation Factor 88; Osteonecrosis; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Time Factors; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Transcription Factor RelA

2014
Femoral perfusion after pulsed electromagnetic field stimulation in a steroid-induced osteonecrosis model.
    Bioelectromagnetics, 2015, Volume: 36, Issue:5

    Topics: Animals; Area Under Curve; Disease Models, Animal; Electric Stimulation Therapy; Femur; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Rabbits; Regional Blood Flow; Time Factors; Treatment Outcome

2015
Abnormal subchondral bone microstructure following steroid administration is involved in the early pathogenesis of steroid-induced osteonecrosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Femur Head; Glucocorticoids; Imaging, Three-Dimensional; Methylprednisolone; Osteonecrosis; Rabbits; X-Ray Microtomography

2016
IL-4 administration exerts preventive effects via suppression of underlying inflammation and TNF-α-induced apoptosis in steroid-induced osteonecrosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Glucocorticoids; Inflammation; Interleukin-4; Macrophages; Methylprednisolone; Mice, Inbred BALB C; Osteoclasts; Osteonecrosis; Recombinant Proteins; Signal Transduction; STAT1 Transcription Factor; Tartrate-Resistant Acid Phosphatase; Tumor Necrosis Factor-alpha

2016
ST1926 Attenuates Steroid-Induced Osteoporosis in Rats by Inhibiting Inflammation Response.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:8

    Topics: Adamantane; Alkaline Phosphatase; Animals; beta Catenin; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Proteins; Bone Resorption; Cinnamates; Gene Expression Regulation; Male; Methylprednisolone; Methylprednisolone Acetate; NF-kappa B; Osteoblasts; Osteoclasts; Osteonecrosis; Osteoprotegerin; Rats; Rats, Wistar; Signal Transduction; Wnt3A Protein

2017
Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.
    BMC musculoskeletal disorders, 2017, 02-02, Volume: 18, Issue:1

    Topics: Angiography; Animals; Antioxidants; Apoptosis; Cholesterol; Disease Models, Animal; Glucocorticoids; Glutathione; Humans; Hydrogen; Immunohistochemistry; In Situ Nick-End Labeling; Incidence; Injections, Intraperitoneal; Male; Malondialdehyde; Methylprednisolone; Osteonecrosis; Oxidative Stress; Rabbits; Random Allocation; Thrombomodulin; Triglycerides

2017
Bilateral Osteonecrosis of the Femoral and Humeral Heads after Short Term Corticosteroid Therapy. A Case Study.
    Ortopedia, traumatologia, rehabilitacja, 2016, Mar-23, Volume: 18, Issue:2

    Topics: Femur Head Necrosis; Humans; Humerus; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Multiple Myeloma; Osteonecrosis; Prednisone

2016
Different magnetic resonance imaging features in two types of nontraumatic rabbit osteonecrosis models.
    Magnetic resonance imaging, 2009, Volume: 27, Issue:2

    Topics: Animals; Bone Marrow; Contrast Media; Disease Models, Animal; Femur; Gadolinium DTPA; Horses; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Rabbits; Statistics, Nonparametric

2009
Steroid-induced osteonecrosis: the number of lesions is related to the dosage.
    The Journal of bone and joint surgery. British volume, 2008, Volume: 90, Issue:9

    Topics: Adult; China; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Osteonecrosis; Severe Acute Respiratory Syndrome

2008
A combination of granulocyte colony-stimulating factor and stem cell factor ameliorates steroid-associated osteonecrosis in rabbits.
    The Journal of rheumatology, 2008, Volume: 35, Issue:11

    Topics: Animals; Drug Therapy, Combination; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Lipopolysaccharides; Magnetic Resonance Imaging; Male; Methylprednisolone; Necrosis; Osteonecrosis; Rabbits; Stem Cell Factor

2008
Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2008, Volume: 13, Issue:5

    Topics: Animals; Cytochrome P-450 CYP3A; Female; Glucocorticoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Liver; Methylprednisolone; Osteonecrosis; Pravastatin; Probucol; Rabbits; Simvastatin

2008
Dose effects of corticosteroids on the development of osteonecrosis in rabbits.
    The Journal of rheumatology, 2008, Volume: 35, Issue:12

    Topics: Adrenal Cortex Hormones; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methylprednisolone; Osteonecrosis; Rabbits

2008
Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits.
    The Journal of rheumatology, 2008, Volume: 35, Issue:12

    Topics: Adrenal Cortex Hormones; Animals; Anticholesteremic Agents; Anticoagulants; Biomarkers; Chemoprevention; Disease Models, Animal; Fatty Acids, Nonesterified; Lipoproteins, LDL; Male; Methylprednisolone; Methylprednisolone Acetate; Odds Ratio; Osteonecrosis; Probucol; Rabbits; Risk Factors; Triglycerides; Warfarin

2008
Functional perfusion MRI predicts later occurrence of steroid-associated osteonecrosis: an experimental study in rabbits.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2009, Volume: 27, Issue:6

    Topics: Adipose Tissue; Animals; Bone Marrow; Disease Models, Animal; Endothelium, Vascular; Glucocorticoids; Ischemia; Lipopolysaccharides; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Predictive Value of Tests; Rabbits; Sensitivity and Specificity; Thromboplastin

2009
Protective effect of genistein aglycone on the development of osteonecrosis of the femoral head and secondary osteoporosis induced by methylprednisolone in rats.
    The Journal of endocrinology, 2009, Volume: 201, Issue:3

    Topics: Algorithms; Animals; Biomarkers; Bone Density; Compressive Strength; Cytoprotection; Drug Evaluation, Preclinical; Female; Femur Head; Genistein; Methylprednisolone; Osteonecrosis; Osteoporosis; Random Allocation; Rats; Rats, Sprague-Dawley; Stress, Mechanical

2009
Low levels of steroid-metabolizing hepatic enzyme (cytochrome P450 3A) activity may elevate responsiveness to steroids and may increase risk of steroid-induced osteonecrosis even with low glucocorticoid dose.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2009, Volume: 14, Issue:6

    Topics: Animals; Cytochrome P-450 CYP3A; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucocorticoids; Liver; Methylprednisolone; Osteonecrosis; Rabbits; Risk Factors

2009
Symptomatic, steroid-induced, multifocal diaphyseal osteonecrosis in a patient with multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2010, Volume: 16, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Diaphyses; Female; Femur; Humans; Magnetic Resonance Imaging; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting; Orthopedic Procedures; Osteonecrosis; Pain; Pain Measurement; Pulse Therapy, Drug; Talus; Tibia; Treatment Outcome

2010
Vitamin E prevents steroid-induced osteonecrosis in rabbits.
    Acta orthopaedica, 2010, Volume: 81, Issue:1

    Topics: alpha-Tocopherol; Animals; Disease Models, Animal; Femur Head Necrosis; Glucocorticoids; Male; Methylprednisolone; Osteonecrosis; Rabbits; Vitamins

2010
Effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits.
    International journal of experimental pathology, 2010, Volume: 91, Issue:3

    Topics: Animals; Anticholesteremic Agents; Anticoagulants; Bone Marrow Cells; Cholesterol; Enoxaparin; Fatty Acids, Nonesterified; Glucocorticoids; Lovastatin; Male; Methylprednisolone; Osteonecrosis; Rabbits; Triglycerides

2010
Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
    Transplantation proceedings, 2010, Volume: 42, Issue:7

    Topics: Azathioprine; Bone Density; Bone Diseases; Bone Diseases, Metabolic; Creatinine; Female; Humans; Kidney Transplantation; Lipids; Male; Methylprednisolone; Mycophenolic Acid; Osteonecrosis; Osteoporosis; Sirolimus; Vitamin D

2010
Lipoic acid prevents steroid-induced osteonecrosis in rabbits.
    Rheumatology international, 2012, Volume: 32, Issue:6

    Topics: Animals; Biomarkers; Cholesterol; Cytoprotection; Disease Models, Animal; Endothelins; Femur; Glutathione; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Oxidative Stress; Protective Agents; Rabbits; Thioctic Acid; Time Factors

2012
Steroid-induced osteonecrosis of bilateral distal humerus treated by arthroplasty using costal osteochondral graft: case report.
    The Journal of hand surgery, 2011, Volume: 36, Issue:5

    Topics: Adult; Arthroplasty; Bone Transplantation; Cartilage; Dose-Response Relationship, Drug; Drug Administration Schedule; Elbow Joint; Follow-Up Studies; Humans; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Pain Measurement; Range of Motion, Articular; Risk Assessment; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome

2011
Effects of an anti-platelet drug on the prevention of steroid-induced osteonecrosis in rabbits.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:5

    Topics: Animals; Clopidogrel; Femur; Glucocorticoids; Humerus; Male; Methylprednisolone; Osteonecrosis; Platelet Aggregation Inhibitors; Rabbits; Ticlopidine

2012
Clopidogrel: a drug with potential to prevent steroid-induced osteonecrosis?
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:5

    Topics: Clopidogrel; Glucocorticoids; Humans; Methylprednisolone; Osteonecrosis; Platelet Aggregation Inhibitors; Ticlopidine

2012
Pulsed electromagnetic fields stimulation prevents steroid-induced osteonecrosis in rats.
    BMC musculoskeletal disorders, 2011, Sep-29, Volume: 12

    Topics: Animals; Disease Models, Animal; Electromagnetic Fields; Gene Expression; Glucocorticoids; Injections, Intravenous; Lipids; Lipopolysaccharides; Magnetic Field Therapy; Male; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Pulsed Radiofrequency Treatment; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta1

2011
Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:5

    Topics: Animals; Bone Marrow Transplantation; Bone Regeneration; Cryopreservation; Disease Models, Animal; Femur Head; Femur Head Necrosis; Glucocorticoids; Male; Methylprednisolone; Monocytes; Osteonecrosis; Rabbits

2012
G-CSF/SCF exert beneficial effects via anti-apoptosis in rabbits with steroid-associated osteonecrosis.
    Experimental and molecular pathology, 2013, Volume: 94, Issue:1

    Topics: Acid Phosphatase; Animals; Apoptosis; Caspase 3; Granulocyte Colony-Stimulating Factor; Isoenzymes; Methylprednisolone; Osteocalcin; Osteogenesis; Osteonecrosis; Rabbits; Stem Cell Factor; Tartrate-Resistant Acid Phosphatase

2013
Immunosuppressant-related hip pain after orthotopic liver transplant.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2013, Volume: 11, Issue:1

    Topics: Adult; Aged; Arthralgia; Calcineurin Inhibitors; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hip Joint; Humans; Immunosuppressive Agents; Incidence; Liver Cirrhosis; Liver Failure; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Osteoporosis; Retrospective Studies; Risk Factors; Tacrolimus

2013
Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation.
    Chinese medical journal, 2012, Volume: 125, Issue:14

    Topics: Adult; Aged; Cyclosporine; Female; Femur Head Necrosis; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Retrospective Studies; Risk Factors; Sirolimus; Tacrolimus; Young Adult

2012
Edaravone, a novel free radical scavenger, prevents steroid-induced osteonecrosis in rabbits.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:3

    Topics: Animals; Antipyrine; DNA Damage; Edaravone; Free Radical Scavengers; Glucocorticoids; Glutathione; Lipid Peroxidation; Male; Methylprednisolone; Osteonecrosis; Oxidative Stress; Rabbits; Treatment Outcome

2013
Preventive effects of the anti-vasospasm agent via the regulation of the Rho-kinase pathway on the development of steroid-induced osteonecrosis in rabbits.
    Bone, 2013, Volume: 53, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Cortex Hormones; Animals; Male; Methylprednisolone; Osteonecrosis; Rabbits; rho-Associated Kinases; Steroids

2013
Spinal blood flow in 24-hour megadose glucocorticoid treatment in awake pigs.
    Journal of neurosurgery, 2003, Volume: 99, Issue:3 Suppl

    Topics: Animals; Anti-Inflammatory Agents; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Ischemia; Methylprednisolone; Osteonecrosis; Regional Blood Flow; Risk Factors; Spinal Cord; Spinal Cord Injuries; Spine; Swine

2003
[Aseptic osteonecrosis after steroid treatment].
    Zeitschrift fur Rheumatologie, 2004, Volume: 63, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Cervical Vertebrae; Contusions; Drug Administration Schedule; Female; Femur; Humans; Infusions, Intravenous; Knee Joint; Magnetic Resonance Imaging; Methylprednisolone; Osteonecrosis; Risk Factors; Spinal Cord Injuries; Tibia

2004
Oxidative stress and vascular permeability in steroid-induced osteonecrosis model.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2004, Volume: 9, Issue:5

    Topics: Animals; Capillary Permeability; Disease Models, Animal; Female; Glucocorticoids; Glutathione; Lipid Peroxides; Methylprednisolone; Osteonecrosis; Oxidative Stress; Rabbits

2004
Combined effects of an anticoagulant and a lipid-lowering agent on the prevention of steroid-induced osteonecrosis in rabbits.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:10

    Topics: Adipocytes; Animals; Anticholesteremic Agents; Anticoagulants; Bone Marrow; Drug Therapy, Combination; Glucocorticoids; Injections, Intramuscular; Lipids; Male; Methylprednisolone; Osteonecrosis; Probucol; Rabbits; Warfarin

2004
DNA oxidation injury in bone early after steroid administration is involved in the pathogenesis of steroid-induced osteonecrosis.
    Rheumatology (Oxford, England), 2005, Volume: 44, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Diaphyses; Disease Models, Animal; DNA Damage; Female; Glucocorticoids; Methylprednisolone; Osteonecrosis; Oxidation-Reduction; Oxidative Stress; Rabbits

2005
[Report on the investigation of lower extremity osteonecrosis with magnetic resonance imaging in recovered severe acute respiratory syndrome in Guangzhou].
    Zhonghua yi xue za zhi, 2004, Nov-02, Volume: 84, Issue:21

    Topics: Adolescent; Adult; China; Convalescence; Female; Femur Head Necrosis; Humans; Lower Extremity; Magnetic Resonance Imaging; Male; Mass Screening; Methylprednisolone; Middle Aged; Osteonecrosis; Severe Acute Respiratory Syndrome

2004
Osteonecrosis of hip and knee in patients with severe acute respiratory syndrome treated with steroids.
    Radiology, 2005, Volume: 235, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Femur Head Necrosis; Glucocorticoids; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Severe Acute Respiratory Syndrome

2005
Very early development of steroid-associated osteonecrosis of femoral head in systemic lupus erythematosus: prospective study by MRI.
    Lupus, 2005, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Case-Control Studies; Cholesterol; Female; Femur Head; Glucocorticoids; Humans; Leukocyte Count; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Prednisolone; Prospective Studies; Pulse Therapy, Drug; Serum Albumin

2005
Onset of steroid-induced osteonecrosis in rabbits and its relationship to hyperlipaemia and increased free fatty acids.
    Rheumatology (Oxford, England), 2005, Volume: 44, Issue:10

    Topics: Animals; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Glucocorticoids; Hyperlipidemias; Methylprednisolone; Osteonecrosis; Rabbits; Time Factors

2005
Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone.
    Bone, 2006, Volume: 39, Issue:4

    Topics: Animals; Bone Marrow Cells; Dose-Response Relationship, Drug; Femur; Injections, Intramuscular; Injections, Intravenous; Lipopolysaccharides; Lipoproteins, HDL; Lipoproteins, LDL; Magnetic Resonance Imaging; Male; Methylprednisolone; Multivariate Analysis; Osteonecrosis; Partial Thromboplastin Time; Plasminogen Activator Inhibitor 1; Rabbits; Time Factors; Tissue Plasminogen Activator; Tomography, X-Ray Computed

2006
Symptomatic osteonecrosis of the hip and knee after cardiac transplantation.
    The Journal of arthroplasty, 2008, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Femur Head Necrosis; Glucocorticoids; Heart Transplantation; Humans; Immunosuppressive Agents; Knee Joint; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Prednisone; Retrospective Studies

2008
Regenerative effects of transplanting autologous mesenchymal stem cells on corticosteroid-induced osteonecrosis in rabbits.
    Modern rheumatology, 2008, Volume: 18, Issue:2

    Topics: Animals; Apoptosis; Bone Marrow; Bone Marrow Transplantation; Disease Models, Animal; Femur; Glucocorticoids; In Situ Nick-End Labeling; Injections; Male; Mesenchymal Stem Cell Transplantation; Methylprednisolone; Osteonecrosis; Rabbits; Regeneration; Transplantation, Autologous; Vascular Endothelial Growth Factor A

2008
Pitavastatin may reduce risk of steroid-induced osteonecrosis in rabbits: a preliminary histological study.
    Clinical orthopaedics and related research, 2008, Volume: 466, Issue:5

    Topics: Adipocytes; Animals; Bone Marrow Cells; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Disease Models, Animal; Femur; Femur Head Necrosis; Humerus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Pilot Projects; Quinolines; Rabbits; Time Factors

2008
[Multiple bioimaging modalities in evaluation of an experimental osteonecrosis model induced by a combination of lipopolysaccharide and methylprednisolone].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:3

    Topics: Adipocytes; Animals; Blood Vessels; Bone Marrow Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Femur; Hormones; Lipopolysaccharides; Lipoproteins, HDL; Lipoproteins, LDL; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Plasminogen Activator Inhibitor 1; Rabbits; Tissue Plasminogen Activator; Tomography, X-Ray Computed

2008
Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits.
    Joint bone spine, 2008, Volume: 75, Issue:5

    Topics: Adipocytes; Animals; Bone Marrow Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Femur; Glucocorticoids; Humerus; Lipids; Lipopolysaccharides; Longevity; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Plasminogen Activator Inhibitor 1; Pressure; Rabbits; Tissue Plasminogen Activator

2008
Isolation of prostaglandin E2-like material from osteonecrosis induced by steroids and its prevention by kallikrein-inhibitor, aprotinin. An experimental study in rabbits.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 13, Issue:2

    Topics: Animals; Aprotinin; Methylprednisolone; Osteonecrosis; Prostaglandins E; Rabbits

1984
Glucocorticoids and avascular bone necrosis in renal transplantation.
    Advances in experimental medicine and biology, 1984, Volume: 171

    Topics: Adult; Drug Therapy, Combination; Female; Femur Head Necrosis; Glucocorticoids; Graft Rejection; Humans; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Prednisone

1984
Aseptic necrosis of the knee: bone scintigraphy.
    AJR. American journal of roentgenology, 1982, Volume: 138, Issue:3

    Topics: Adolescent; Adult; Diphosphonates; Etidronic Acid; Female; Femur; Humans; Kidney Transplantation; Knee; Methylprednisolone; Organotechnetium Compounds; Osteonecrosis; Radionuclide Imaging; Technetium; Technetium Tc 99m Medronate

1982
Advantage of long-term alternate day steroid therapy in renal transplantation: a controlled study.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1980, Volume: 10

    Topics: Adult; Azathioprine; Bacterial Infections; Cadaver; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Long-Term Care; Methylprednisolone; Middle Aged; Osteonecrosis; Time Factors; Transplantation, Homologous

1980
[Experimental cortisone osteonecrosis. Early stages of bone marrow and trabecular lesions. Preliminary study in pigs].
    Revue du rhumatisme et des maladies osteo-articulaires, 1983, Volume: 50, Issue:3

    Topics: Animals; Bone Marrow; Lipids; Methylprednisolone; Osteonecrosis; Swine; Swine, Miniature; Time Factors

1983
[Experimental study of cortisone-induced osteonecroses in rabbit (author's transl)].
    Archives d'anatomie et de cytologie pathologiques, 1980, Volume: 28, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Methylprednisolone; Osteonecrosis; Rabbits

1980
Corticosteroid enhances the experimental induction of osteonecrosis in rabbits with Shwartzman reaction.
    Clinical orthopaedics and related research, 1995, Issue:316

    Topics: Animals; Bone Marrow Cells; Disease Models, Animal; Femur; Humerus; Male; Methylprednisolone; Osteonecrosis; Rabbits; Shwartzman Phenomenon

1995
Avascular osteonecrosis in patients with SLE: relation to corticosteroid therapy and anticardiolipin antibodies.
    Lupus, 1994, Volume: 3, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antibodies, Anticardiolipin; Child; Female; Humans; Lupus Erythematosus, Systemic; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Risk Factors; Time Factors

1994
Avascular necrosis after treatment of aplastic anaemia with antilymphocyte globulin and high-dose methylprednisolone.
    British journal of haematology, 1993, Volume: 84, Issue:4

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Combined Modality Therapy; Drug Administration Schedule; Female; Femur Head Necrosis; Follow-Up Studies; Humans; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Prednisolone; Retrospective Studies

1993
Avascular necrosis of bone following renal transplantation.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1993, Volume: 83, Issue:9

    Topics: Adult; Alcoholism; Cadaver; Female; Graft Rejection; Humans; Kidney Transplantation; Male; Methylprednisolone; Obesity; Osteonecrosis; Osteoporosis; Postoperative Complications; Risk Factors

1993
High incidence of osteonecrosis of femoral head in patients receiving more than 2 g of intravenous methylprednisolone after renal transplantation.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Female; Femur; Humans; Immunosuppressive Agents; Incidence; Injections, Intravenous; Kidney Transplantation; Male; Methylprednisolone; Osteonecrosis

1996
Effects of pulse methylprednisolone on bone and marrow tissues: corticosteroid-induced osteonecrosis in rabbits.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:11

    Topics: Animals; Blood Platelets; Bone Marrow; Disease Models, Animal; Fatty Liver; Femur; Humerus; Injections; Liver Diseases; Male; Methylprednisolone; Necrosis; Osteonecrosis; Prevalence; Rabbits

1997
Steroid treatment and osteonecrosis: comment on the article by Yamamoto et al.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Bone Marrow; Femur; Humerus; Hyperlipidemias; Methylprednisolone; Osteonecrosis; Rabbits; Swine

1998
The Nicolas Andry award. The pathogenesis and prevention of steroid-induced osteonecrosis.
    Clinical orthopaedics and related research, 2000, Issue:370

    Topics: Adipocytes; Animals; Anticholesteremic Agents; Bone Marrow Cells; Bone Marrow Transplantation; Chickens; Clone Cells; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Gene Expression Regulation; Glucocorticoids; Lovastatin; Methylprednisolone; Mice; Mice, Inbred BALB C; Osteonecrosis; Time Factors; Transfection

2000
Hemorrhage and thrombus formation in early experimental osteonecrosis.
    Clinical orthopaedics and related research, 2001, Issue:386

    Topics: Animals; Autoantibodies; Disease Models, Animal; Female; Femur; Hemorrhage; Methylprednisolone; Mice; Osteonecrosis; Photomicrography; Rabbits; Reference Values; Sensitivity and Specificity; Thrombosis

2001
Bone marrow fat cell enlargement and a rise in intraosseous pressure in steroid-treated rabbits with osteonecrosis.
    Bone, 2002, Volume: 30, Issue:1

    Topics: Adipocytes; Animals; Blood Flow Velocity; Bone Marrow Cells; Cell Size; Disease Models, Animal; Femur; Male; Methylprednisolone; Methylprednisolone Acetate; Osteonecrosis; Pressure; Rabbits

2002
Steroid-induced avascular necrosis.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Female; Humans; Methylprednisolone; Osteonecrosis; Radiography

2002
Avascular necrosis following renal transplantation. Experience with 449 allografts with and without high-dose steroid therapy.
    Urology, 1978, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Graft Rejection; Hip; Humans; Injections, Intravenous; Kidney Transplantation; Knee; Male; Methylprednisolone; Osteonecrosis; Transplantation, Homologous

1978
Corticosteroid-induced avascular necrosis: an experimental study in rabbits.
    Clinical orthopaedics and related research, 1978, Issue:135

    Topics: Adrenal Cortex Hormones; Animals; Bone and Bones; Lipids; Male; Methylprednisolone; Osteonecrosis; Prostaglandins B; Prostaglandins F; Rabbits

1978
High-dose intravenous methylprednisolone therapy associated with osteonecrosis in patients with systemic lupus erythematosus.
    Lupus, 1992, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Lupus Erythematosus, Systemic; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Retrospective Studies

1992
Experimental steroid-induced osteonecrosis in adult rabbits with hypersensitivity vasculitis.
    Clinical orthopaedics and related research, 1992, Issue:277

    Topics: Animals; Blood Proteins; Bone Marrow; Femur; Horses; Kidney; Liver; Methylprednisolone; Methylprednisolone Acetate; Myocardium; Osteonecrosis; Rabbits; Time Factors; Vasculitis

1992
Multifocal osteonecrosis after short-term high-dose corticosteroid therapy. A case report.
    Clinical orthopaedics and related research, 1992, Issue:279

    Topics: Adult; Femur Head Necrosis; Humans; Humerus; Magnetic Resonance Imaging; Male; Methylprednisolone; Osteonecrosis; Osteotomy; Prednisone; Radiography

1992
Avascular necrosis and pulsed methylprednisolone in RA.
    British journal of rheumatology, 1988, Volume: 27, Issue:6

    Topics: Arthritis, Rheumatoid; Female; Hip Joint; Humans; Joint Diseases; Male; Methylprednisolone; Middle Aged; Osteonecrosis

1988
Corticosteroids for rheumatic disease. 1. Physiology, pharmacology, and therapeutic strategies.
    Postgraduate medicine, 1986, Volume: 79, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Drug Administration Schedule; Humans; Hypothalamo-Hypophyseal System; Methylprednisolone; Osteonecrosis; Pituitary-Adrenal System; Prednisone; Rheumatic Diseases

1986
Susceptibility of the rabbit and the rat to steroid osteonecrosis--an experimental study.
    Transplantation, 1987, Volume: 43, Issue:5

    Topics: Animals; Bone and Bones; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Methylprednisolone; Osteonecrosis; Rabbits; Radiography; Radionuclide Imaging; Rats

1987