Compounds > methylprednisolone

methylprednisolone and Chemical and Drug Induced Liver Injury

methylprednisolone has been researched along with Chemical and Drug Induced Liver Injury in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19909 (12.50)18.7374
1990's7 (9.72)18.2507
2000's7 (9.72)29.6817
2010's38 (52.78)24.3611
2020's11 (15.28)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grover, S; Hodi, FS; Li, M; Rahma, OE; Sack, JS; Vogel, AS; Wong, D; Zucker, SD1
Hu, X; Shuai, X; Wei, Y1
Allgeier, J; Gerbes, A; Neumann, J; Todorova, R; Weber, S1
Andrade, RJ; Björnsson, ES; Lucena, MI; Medina-Caliz, I1
Chen, Y; Liu, J; Luo, Y; Rong, P; Shi, C; Yang, B; Yang, J; Zhan, H1
Aguiar, F; Azevedo, AC; Brito, I; Ganhão, S; Martins, FR; Rodrigues, M1
Bleyzac, N; Cottin, J; Dumortier, J; Durrieu, G; Gouraud, A; Pierre, S; Pizzoglio, V; Simon, C1
Boricic, I; Dragasevic, S; Dumic, I; Jankovic, K; Milovanovic, T; Stojkovic Lalosevic, M1
Hasegawa, I; Itoh, Y; Kikukawa, T; Kimura, H; Mino, T; Ohsawa, M; Takeda, A; Uchida-Kobayashi, S1
Simon, EL; Yocum, A1
Shen, M; Tan, S; Tang, L; Wang, F; Xia, S; Xiao, L; Zhang, F; Zhang, Z; Zheng, S1
Chambon-Augoyard, C; Cottin, J; Dumortier, J; Guillaud, O; Hervieu, V; Lavie, C; Scoazec, JY; Vial, T; Vukusic, S1
Abramavicius, S; Kadusevicius, E; Velickiene, D1
Álvarez-Cañas, C; Álvarez-Cuenllas, B; Jiménez, M; Jorquera, F; Linares, P; Monteserín, L; Rodríguez-Martín, L1
Bresteau, C; Perlemuter, G; Prevot, S; Voican, C1
Bianco, A; Biolato, M; De Fino, C; Grieco, A; Losavio, FA; Lucchini, M; Marrone, G; Mirabella, M; Nociti, V1
Adamec, I; Habek, M; Pavičić, T; Pavlović, I; Ruška, B1
Hong, RT; Li, XL; Liu, XC; Shi, H; Song, YL1
Cochran, BP; Kimbrough, EO; Pagán, RJ1
Di Stefano, V; Graziosi, A; Mohn, AA; Rotondo, E1
Haq, MI; Nixon, J; Stanley, AJ1
Drake, SM; Loubser, L; Weider, KI1
Andrade, RJ; Contreras, F; Crespo, J; García-Cortés, M; González-Jiménez, A; Hernández, N; Lucena, MI; Medina-Cáliz, I; Ortega-Alonso, A; Pinazo-Bandera, J; Robles-Díaz, M; Sanabria-Cabrera, J; Sanjuan-Jiménez, R; Zoubek, ME1
D'Agnolo, HM; Drenth, JP1
Caster, O; Conforti, A; Edwards, IR; Viola, E1
Esayag, Y; Goldin, E; Levi, I; Lurie, Y; Melamud, B1
Baiocchini, A; Del Nonno, F; Galati, V; Grilli, E; Petrosillo, N1
Hammerstrom, AE1
Bye, W; Cheng, R; Cooper, A; Kench, J; McNeil, C; Shackel, N; Watson, G1
Albano, E; Brunetto, M; Coco, B; Latrofa, F; Leo, M; Marcocci, C; Marinò, M; Mazzi, B; Menconi, F; Profilo, MA; Rocchi, R; Sisti, E; Vitti, P1
Beck-Peccoz, P; Campi, I; Covelli, D; Currò, N; D'Ambrosio, R; Gianelli, U; Maggioni, M; Salvi, M; Vannucchi, G1
Federzoni, L; Ferraro, D; Losi, L; Mirante, VG; Nichelli, PF; Simone, AM; Sola, P; Villa, E; Vitetta, F1
Brunetto, M; Coco, B; Latrofa, F; Leo, M; Marcocci, C; Marinò, M; Mazzi, B; Menconi, F; Profilo, MA; Rocchi, R; Sisti, E; Vitti, P1
Ahmed, T; Black, J; Pandey, R; Shah, B1
Cipriano, MA; Lopes, S; Oliveira, AT; Sofia, C1
Achiron, A; Ben-Ari, Z; Davidov, Y; Dolev, M; Har-Noy, O; Pappo, O1
Campennì, A; Giuffrida, G; Marinò, M; Moleti, M; Morelli, S; Puxeddu, E; Sisti, E; Squadrito, G; Sturniolo, G; Trimarchi, F; Vermiglio, F1
Arranz, G; López San Román, A; Moreira, VF; Moreno, A; Riesco, JM; Rivero Fernández, M; Ruiz Del Arbol, L1
Alfayate Guerra, R; Arias Mendoza, N; González Sánchez, V; López Macia, A; Mauri Dot, M; Moreno-Pérez, O; Picó Alfonso, A; Sánchez-Ortiga, R1
Giouleme, O; Hytiroglou, P; Karabatsou, S; Katsaros, M; Koliouskas, D; Tsiaousi, E; Xanthis, A1
Chen, Q; Cheng, N; Liu, J; Wang, B; Wang, QY; Xu, DW; Xuan, XQ1
Chang, SC; Hsu, SY; Kuo, LC; Lai, JI; Lai, YC; Lin, PC; Wang, WS1
Gučev, F; Hočevar, A; Marolt, VF; Perdan-Pirkmajer, K; Rotar, Ž; Tomšič, M; Žibert, J1
Carrier, P; Crepin, S; Debette-Gratien, M; Godet, B; Gondran, G; Jacques, J; Labrousse, F; Loustaud-Ratti, V; Magy, L; Pillegand, B; Sautereau, D; Vidal, E1
DINES, DE1
Argaud, L; Boillot, O; Descloux, E; Dumortier, J; Robert, D; Scoazec, JY1
Boccadoro, M; Campa, E; Dellacasa, C; Fava, C; Ferrero, D; Fumagalli, M; Mattioli, G; Perfetti, P; Pogliani, EM; Rege-Cambrin, G1
Akbulut, S; Altiparmak, E; Küçükazman, M; Ozaslan, E; Topal, F; Yüksel, O1
Yasuda, H; Yoshiba, S1
Huber, C; Kathrein, H; Koenig, P; Lang, A; Margreiter, R; Spielberger, M; Steiner, E1
Andersen, O; Lindberg, C; Olsson, R1
Chelstrom, LM; Clementson, D; Covalciuc, K; Gunther, R; Irvin, JD; Johnson, B; Myers, DE; Schneider, EA; Uckun, FM; Wendorf, HR1
Fritsche, H; Ippoliti, C; Khouri, I; Körbling, M; Przepiorka, D; Warkentin, D; Woo, M1
Tokura, Y; Urano, S1
Choudhary, A; Leitze, Z; Manthous, CA; Nadeem, A; Roberts, I; Saul, Z1
Cartner, S; Contreras, JL; Eckhoff, DE; Frenette, L; Neville, DM; Robbin, ML; Thomas, FT; Thomas, JM1
Bhagwati, N; Horton, C; Kulkarni, S; Mainwaring, P; Mehta, J; Pandha, H; Powles, R; Singhal, S; Sirohi, B; Treleaven, J1
Berne, TV; Chatterjee, SN; Craig, JR; Payne, JE1
Galvin, MJ; Lefer, AM; Shupe, K1
Goldbach, M; Phillips, MJ; Roberts, EA; Spielberg, SP1
Lebetkin, E; Luster, MI; Rosenthal, GJ; Thigpen, JE; Tucker, AN; Wilson, R1
Jegasothy, BV; Lazarus, GS; Sherertz, EF1
Böhmig, HJ; Egert, H; Pinggera, WF; Stummvoll, HK1
Kuster, GG; Woods, JE1
Bartoloni Saint Omer, F; Gallo, C; Gori, F1

Reviews

12 review(s) available for methylprednisolone and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Acute hepatitis secondary to high-dose intravenous methylprednisolone.
    Gastroenterologia y hepatologia, 2018, Volume: 41, Issue:8

    Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Therapy, Combination; Female; Hearing Loss, Sudden; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Methylprednisolone; Middle Aged; Pregnenediones

2018
Suspected drug-induced liver injury associated with iguratimod: a case report and review of the literature.
    BMC gastroenterology, 2018, Aug-24, Volume: 18, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Chromones; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methylprednisolone; Middle Aged; Sjogren's Syndrome; Sulfonamides

2018
Liver injury after methylprednisolone pulses: A disputable cause of hepatotoxicity. A case series and literature review.
    United European gastroenterology journal, 2019, Volume: 7, Issue:6

    Topics: Administration, Intravenous; Adult; Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Graves Disease; Humans; Liver Function Tests; Methylprednisolone; Middle Aged; Multiple Sclerosis

2019
High-dose methylprednisolone-induced hepatitis in a patient with multiple sclerosis: a case report and brief review of literature.
    The Netherlands journal of medicine, 2013, Volume: 71, Issue:4

    Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Injections, Intravenous; Methylprednisolone; Middle Aged; Multiple Sclerosis; Recurrence

2013
Ipilimumab-induced toxicities and the gastroenterologist.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:4

    Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury; Colitis; Glucocorticoids; Humans; Immunosuppressive Agents; Infliximab; Ipilimumab; Melanoma; Methylprednisolone; Mycophenolic Acid; Patient Care Team; Prednisolone; Pulse Therapy, Drug

2015
Methylprednisolone-induced liver injury: Case report and literature review.
    Journal of digestive diseases, 2016, Volume: 17, Issue:1

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Humans; Liver; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting; Young Adult

2016
Acute liver damage following intravenous glucocorticoid treatment for Graves' ophthalmopathy.
    Endocrine, 2016, Volume: 54, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Infusions, Intravenous; Male; Methylprednisolone; Middle Aged

2016
[Recurrent acute liver toxicity from intravenous methylprednisolone].
    Revista espanola de enfermedades digestivas, 2008, Volume: 100, Issue:11

    Topics: Acute Disease; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Injections, Intravenous; Liver; Methylprednisolone; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Necrosis; Recurrence

2008
4,4'-Methylenedianiline-induced hepatitis in an industrial worker: case report and review of the literature.
    Human & experimental toxicology, 2011, Volume: 30, Issue:7

    Topics: Acute Disease; Adult; Allergens; Aniline Compounds; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Function Tests; Male; Methylprednisolone; Occupational Diseases; Treatment Outcome

2011
[Fulminant hepatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; Hypoglycemic Agents; Ibuprofen; Immunosuppressive Agents; Liver Failure, Acute; Methylprednisolone; Pulse Therapy, Drug; Time Factors

2007
Toxicities of tacrolimus and cyclosporin A after allogeneic blood stem cell transplantation.
    Bone marrow transplantation, 1997, Volume: 20, Issue:12

    Topics: Acute Kidney Injury; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Hyperglycemia; Hyperkalemia; Hypertension; Immunosuppressive Agents; Incidence; Infections; Male; Methylprednisolone; Middle Aged; Patient Compliance; Retrospective Studies; Seizures; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

1997

Trials

2 trial(s) available for methylprednisolone and Chemical and Drug Induced Liver Injury

ArticleYear
Cyclosporine in the treatment of acute allograft rejection refractory to high-dose methylprednisolone: results of a prospectively randomized trial.
    Transplantation proceedings, 1984, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cyclosporins; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Methylprednisolone; Middle Aged

1984
The role of autologous transplantation in patients with multiple myeloma aged 65 years and over.
    Bone marrow transplantation, 2000, Volume: 25, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Chemical and Drug Induced Liver Injury; Cohort Studies; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Graft Survival; Heart Diseases; Hematopoietic Stem Cell Mobilization; Hospitalization; Humans; Interferons; Kidney Diseases; Male; Matched-Pair Analysis; Melphalan; Methylprednisolone; Middle Aged; Multiple Myeloma; Neutropenia; Neutrophils; Platelet Count; Recurrence; Sepsis; Survival Rate; Thrombocytopenia; Transplantation, Autologous; Vincristine

2000

Other Studies

58 other study(ies) available for methylprednisolone and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of corticosteroid dosing on outcomes in high-grade immune checkpoint inhibitor hepatitis.
    Hepatology (Baltimore, Md.), 2022, Volume: 75, Issue:3

    Topics: Adrenal Cortex Hormones; Alanine Transaminase; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Resistance; Female; Humans; Immune Checkpoint Inhibitors; Immunosuppression Therapy; Liver Function Tests; Male; Methylprednisolone; Middle Aged; Neoplasms; Outcome and Process Assessment, Health Care; Retrospective Studies; Risk Assessment

2022
Case Report: Glucocorticoid Effect Observation in a Ureteral Urothelial Cancer Patient With ICI-Associated Myocarditis and Multiple Organ Injuries.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Glucocorticoids; Humans; Immune Checkpoint Inhibitors; Male; Methylprednisolone; Myocarditis; Myositis; Programmed Cell Death 1 Receptor; Severity of Illness Index; Time Factors; Treatment Outcome; Ureteral Neoplasms

2021
Acute liver injury following methylprednisolone pulse therapy: 13 cases from a prospectively collected cohort.
    European journal of gastroenterology & hepatology, 2022, 04-01, Volume: 34, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Hepatitis, Autoimmune; Humans; Methylprednisolone; Prospective Studies

2022
Setting up criteria for drug-induced autoimmune-like hepatitis through a systematic analysis of published reports.
    Hepatology communications, 2022, Volume: 6, Issue:8

    Topics: Adalimumab; Chemical and Drug Induced Liver Injury; Diclofenac; Female; Hepatitis A; Hepatitis, Autoimmune; Humans; Imatinib Mesylate; Infliximab; Interferons; Methyldopa; Methylprednisolone; Minocycline; Nitrofurantoin

2022
Drug-induced liver injury in COVID-19 patients during hospitalization.
    Medicine, 2023, Mar-17, Volume: 102, Issue:11

    Topics: Chemical and Drug Induced Liver Injury; COVID-19; Hospitalization; Humans; Methylprednisolone; Plant Extracts; Retrospective Studies

2023
Anakinra and hepatotoxicity in pediatric rheumatology: a case series.
    Pediatric rheumatology online journal, 2023, Oct-06, Volume: 21, Issue:1

    Topics: Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Exanthema; Ferritins; Fever; Humans; Immunoglobulins, Intravenous; Interleukin 1 Receptor Antagonist Protein; Macrophage Activation Syndrome; Male; Methylprednisolone; Rheumatology

2023
Methylprednisolone-related liver injury: A descriptive study using the French pharmacovigilance database.
    Clinics and research in hepatology and gastroenterology, 2020, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Databases, Factual; Female; France; Humans; Infant; Male; Methylprednisolone; Middle Aged; Pharmacovigilance; Young Adult

2020
Methylprednisolone induced liver injury in a patient with multiple sclerosis.
    Journal of gastrointestinal and liver diseases : JGLD, 2020, 03-13, Volume: 29, Issue:1

    Topics: Administration, Intravenous; Adult; Biopsy; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Liver; Liver Function Tests; Methylprednisolone; Multiple Sclerosis; Remission Induction; Withholding Treatment

2020
Liver injury after methylprednisolone pulse therapy in multiple sclerosis is usually due to idiosyncratic drug-induced toxicity rather than autoimmune hepatitis.
    Multiple sclerosis and related disorders, 2020, Volume: 42

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Hepatitis, Autoimmune; Humans; Immunologic Factors; Methylprednisolone; Middle Aged; Multiple Sclerosis

2020
Thrombotic Thrombocytopenic Purpura after Ad26.COV2-S Vaccination.
    The American journal of emergency medicine, 2021, Volume: 49

    Topics: Acute Kidney Injury; Ad26COVS1; Chemical and Drug Induced Liver Injury; COVID-19 Vaccines; Female; Humans; Mental Disorders; Methylprednisolone; Middle Aged; Plasma Exchange; Purpura, Thrombotic Thrombocytopenic; Renal Dialysis; Treatment Outcome

2021
Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.
    Journal of ethnopharmacology, 2021, Nov-15, Volume: 280

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; End Stage Liver Disease; Gene Expression Regulation; Hepatocytes; Liver; Male; Methylprednisolone; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley

2021
Methylprednisolone liver toxicity: A new case and a French regional pharmacovigilance survey.
    Clinics and research in hepatology and gastroenterology, 2017, Volume: 41, Issue:4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; France; Glucocorticoids; Humans; Male; Methylprednisolone; Pharmacovigilance

2017
Methimazole-induced liver injury overshadowed by methylprednisolone pulse therapy: Case report.
    Medicine, 2017, Volume: 96, Issue:39

    Topics: Administration, Intravenous; Aged; Antithyroid Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Liver Function Tests; Medication Therapy Management; Methimazole; Methylprednisolone; Optic Nerve Diseases; Pulse Therapy, Drug; Symptom Assessment; Thyrotoxicosis; Treatment Outcome

2017
Methylprednisolone-induced acute liver injury in a patient treated for multiple sclerosis relapse.
    BMJ case reports, 2018, Mar-05, Volume: 2018

    Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Chronic Disease; Glucocorticoids; Humans; Liver; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting

2018
Liver injury after pulsed methylprednisolone therapy in multiple sclerosis patients.
    Brain and behavior, 2018, Volume: 8, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Monitoring; Female; Glucocorticoids; Humans; Italy; Liver Function Tests; Male; Methylprednisolone; Middle Aged; Multiple Sclerosis; Prevalence; Prospective Studies; Pulse Therapy, Drug; Secondary Prevention; Severity of Illness Index

2018
Toxic liver injury after high-dose methylprednisolone in people with multiple sclerosis.
    Multiple sclerosis and related disorders, 2018, Volume: 25

    Topics: Adult; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Methylprednisolone; Middle Aged; Multiple Sclerosis

2018
62-Year-Old Man With Fever and Pruritic Rash.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:11

    Topics: Adrenal Cortex Hormones; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity Syndrome; Fever; Humans; Male; Methylprednisolone; Middle Aged; Pruritus; Transaminases

2018
Methylprednisolone-induced hepatotoxicity in a 16-year-old girl with multiple sclerosis.
    BMJ case reports, 2018, Dec-07, Volume: 11, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Glucocorticoids; Humans; Methylprednisolone; Multiple Sclerosis; Pulse Therapy, Drug

2018
Imatinib and liver toxicity.
    BMJ case reports, 2018, Dec-07, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Duodenal Neoplasms; Female; Gastrointestinal Stromal Tumors; Glucocorticoids; Humans; Imatinib Mesylate; Liver Function Tests; Methylprednisolone; Middle Aged; Protein Kinase Inhibitors; Treatment Outcome

2018
Acute liver injury induced by red yeast rice supplement.
    BMJ case reports, 2019, Mar-25, Volume: 12, Issue:3

    Topics: Biological Products; Chemical and Drug Induced Liver Injury; Dietary Supplements; Female; Glucocorticoids; Humans; Methylprednisolone; Middle Aged

2019
Methylprednisolone-induced hepatotoxicity: experiences from global adverse drug reaction surveillance.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Methylprednisolone; Middle Aged

2014
Methylprednisolone-induced liver injury: a diagnostic challenge.
    The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:3

    Topics: Administration, Intravenous; Chemical and Drug Induced Liver Injury; Glucocorticoids; Graves Ophthalmopathy; Humans; Male; Methylprednisolone; Middle Aged; Pulse Therapy, Drug

2014
Incomplete septal cirrhosis after high-dose methylprednisolone therapy and regression of liver injury.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:2

    Topics: Administration, Intravenous; Adult; Chemical and Drug Induced Liver Injury; Cholecystectomy; Female; Gallstones; Humans; Liver Cirrhosis; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting; Optic Neuritis; Ultrasonography

2015
Possible amlodipine-induced hepatotoxicity after stem cell transplant.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:1

    Topics: Aged; Alanine Transaminase; Amlodipine; Antihypertensive Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Hypertension; Liver Function Tests; Male; Methylprednisolone; Prednisone

2015
Intravenous glucocorticoid therapy for Graves' ophthalmopathy and acute liver damage: an epidemiological study.
    European journal of endocrinology, 2015, Volume: 172, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Alanine Transaminase; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Male; Methylprednisolone; Methylprednisolone Acetate; Middle Aged; Retrospective Studies; Young Adult

2015
Statins may increase the risk of liver dysfunction in patients treated with steroids for active graves' orbitopathy.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylprednisolone; Middle Aged; Simvastatin

2015
Methylprednisolone-induced Toxic Hepatitis After Intravenous Pulsed Therapy for Multiple Sclerosis Relapses.
    The neurologist, 2015, Volume: 19, Issue:6

    Topics: Administration, Intravenous; Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Methylprednisolone; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Pulse Therapy, Drug; Young Adult

2015
Age and Dose Are Major Risk Factors for Liver Damage Associated with Intravenous Glucocorticoid Pulse Therapy for Graves' Orbitopathy.
    Thyroid : official journal of the American Thyroid Association, 2015, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Cohort Studies; Dose-Response Relationship, Drug; Female; gamma-Glutamyltransferase; Glucocorticoids; Graves Ophthalmopathy; Humans; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Acetate; Middle Aged; Multivariate Analysis; Regression Analysis; Retrospective Studies; Risk Factors; Young Adult

2015
Resolution of ipilimumab induced severe hepatotoxicity with triple immunosuppressants therapy.
    BMJ case reports, 2015, Jul-14, Volume: 2015

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Australia; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Horses; Humans; Immunosuppressive Agents; Ipilimumab; Melanoma; Methylprednisolone; Middle Aged; Mycophenolic Acid

2015
Induced liver injury after high-dose methylprednisolone in a patient with multiple sclerosis.
    BMJ case reports, 2015, Jul-21, Volume: 2015

    Topics: Acute Disease; Adult; Biopsy; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Female; Glatiramer Acetate; Hepatitis; Humans; Immunoglobulins; Liver; Liver Function Tests; Methylprednisolone; Multiple Sclerosis

2015
High-dose intravenous methylprednisolone: liver injury.
    Prescrire international, 2015, Volume: 24, Issue:165

    Topics: Administration, Intravenous; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glucocorticoids; Humans; Methylprednisolone

2015
Treatment of Graves' ophthalmopathy with high-dose intravenous methylprednisolone: a comparison of two dosing regimens.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:3

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Graves Ophthalmopathy; Hashimoto Disease; Humans; Hyperglycemia; Infusions, Intravenous; Male; Methylprednisolone; Middle Aged; Pulse Therapy, Drug; Recurrence; Retrospective Studies; Treatment Outcome

2009
[The curative effects of different drugs on liver cell damage of rats induced by acute nickel carbonyl poisoning].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; DNA Damage; Drugs, Chinese Herbal; Hepatocytes; Male; Methylprednisolone; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Sodium Selenite; Zalcitabine

2011
Successful treatment of erlotinib-induced acute hepatitis and acute interstitial pneumonitis with high-dose corticosteroid: a case report and literature review.
    International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:7

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Alanine Transaminase; Anti-Inflammatory Agents; Antineoplastic Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; ErbB Receptors; Erlotinib Hydrochloride; Humans; Liver Function Tests; Lung Diseases, Interstitial; Lung Neoplasms; Male; Methylprednisolone; Muscle Weakness; Quinazolines; Radiography, Thoracic

2011
Tumour necrosis factor-alpha inhibitor-induced hepatic injury in patients with rheumatoid arthritis: two case reports and an analysis of the laboratory data from the Slovenian national biologicals registry.
    Rheumatology international, 2013, Volume: 33, Issue:11

    Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Methylprednisolone; Registries; Slovenia; Sulfasalazine; Tumor Necrosis Factor-alpha

2013
Acute liver toxicity due to methylprednisolone: consider this diagnosis in the context of autoimmunity.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:1

    Topics: Adult; Autoimmunity; Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Humans; Methylprednisolone; Multiple Sclerosis

2013
POLYARTERITIS NODOSA. REPORT OF A PATIENT RECEIVING LONG-TERM ANTICOAGULANT THERAPY.
    JAMA, 1964, Jul-13, Volume: 189

    Topics: Anticoagulants; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Guanethidine; Hepatitis; Humans; Hydrochlorothiazide; Hypertension; Methylprednisolone; Polyarteritis Nodosa; Thrombophlebitis; Warfarin

1964
Favourable issue of a fulminant hepatitis associated with sulfasalazine DRESS syndrome without liver transplantation.
    Intensive care medicine, 2005, Volume: 31, Issue:12

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Liver Failure, Acute; Methylprednisolone; Middle Aged; Sulfasalazine

2005
Corticosteroids can reverse severe imatinib-induced hepatotoxicity.
    Haematologica, 2006, Volume: 91, Issue:6 Suppl

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Benzamides; Chemical and Drug Induced Liver Injury; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver; Liver Diseases; Methylprednisolone; Piperazines; Prednisone; Pyrimidines

2006
Methylprednisolone-induced toxic hepatitis.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Methylprednisolone; Middle Aged

2006
Centrolobular liver cell necrosis, myocardial infarction, and hyperamylasaemia after high dose corticosteroids.
    BMJ (Clinical research ed.), 1994, Feb-12, Volume: 308, Issue:6926

    Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Diseases; Male; Methylprednisolone; Necrosis; Transaminases

1994
Toxicity profile of the investigational new biotherapeutic agent, B43 (anti-CD19)-pokeweed antiviral protein immunotoxin.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigens, CD19; Antineoplastic Agents, Phytogenic; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Dopamine; Female; Immunotoxins; Injections, Intraperitoneal; Injections, Intravenous; Kidney Tubular Necrosis, Acute; Methylprednisolone; Mice; Mice, Inbred BALB C; Muscular Diseases; N-Glycosyl Hydrolases; Pentoxifylline; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Single-Blind Method

1996
An erythema multiforme-like eruption caused by exposure to 1-chloromethylnaphthalene.
    The Journal of dermatology, 1998, Volume: 25, Issue:1

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Chemical Industry; Erythema Multiforme; Glucocorticoids; Humans; Lymphocyte Activation; Male; Methylprednisolone; Naphthalenes; Occupational Diseases; Patch Tests; Tears; Xerophthalmia

1998
Nevirapine-induced hepatitis treated with corticosteroids?
    AIDS (London, England), 1998, Jun-18, Volume: 12, Issue:9

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; HIV Infections; Humans; Methylprednisolone; Nevirapine; Reverse Transcriptase Inhibitors

1998
Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients.
    Transplantation, 1999, Jul-27, Volume: 68, Issue:2

    Topics: Animals; Capillary Leak Syndrome; CD3 Complex; Chemical and Drug Induced Liver Injury; Cyclosporine; Immune Tolerance; Immunotoxins; Islets of Langerhans Transplantation; Kidney Function Tests; Kidney Transplantation; Liver Function Tests; Macaca mulatta; Male; Methylprednisolone; Transplantation Conditioning

1999
Hepatic dysfunction in recipients of renal allografts.
    Surgery, gynecology & obstetrics, 1975, Volume: 141, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Antigens, Viral; Aspartate Aminotransferases; Azathioprine; Bilirubin; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytomegalovirus; Hepatitis B virus; Humans; Kidney Transplantation; Liver; Liver Diseases; Methylprednisolone; Prednisone; Transplantation, Homologous

1975
Anti-endotoxin actions of methylprednisolone in the isolated perfused cat liver.
    Pharmacology, 1978, Volume: 17, Issue:4

    Topics: Animals; Cathepsins; Cats; Chemical and Drug Induced Liver Injury; Endotoxins; Female; L-Lactate Dehydrogenase; Liver; Lysosomes; Male; Methylprednisolone; Oxygen Consumption; Vacuoles

1978
Phenobarbital hepatotoxicity in an 8-month-old infant.
    Journal of hepatology, 1990, Volume: 10, Issue:2

    Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; Male; Methylprednisolone; Phenobarbital; Phenytoin

1990
Characteristics of 2,3,7,8-tetrachlorodibenzo-p-dioxin induced endotoxin hypersensitivity: association with hepatotoxicity.
    Toxicology, 1989, Jun-16, Volume: 56, Issue:3

    Topics: Alanine Transaminase; Animals; Blood Glucose; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Dioxins; Drug Interactions; Endotoxins; Female; Lipids; Liver Diseases; Methylprednisolone; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA

1989
Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".
    Journal of the American Academy of Dermatology, 1985, Volume: 12, Issue:1 Pt 2

    Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Humans; Male; Methylprednisolone; Middle Aged; Phenytoin; Stevens-Johnson Syndrome

1985
[Cyclophosphamide therapy in kidney transplants].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:4

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Drug Therapy, Combination; Female; Graft Rejection; Hepatitis; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Methylprednisolone; Transaminases; Transplantation, Homologous

1973
Metabolism of high doses of methylprednisolone by the isolated perfused liver of different species.
    The Journal of surgical research, 1972, Volume: 13, Issue:1

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Chemotherapy, Cancer, Regional Perfusion; Dogs; Liver; Liver Diseases; Methylprednisolone; Necrosis; Nitrosamines; Rabbits; Species Specificity; Swine

1972
[The problem of symplasms in pathology of the liver in the newborn. Critical note on some experimental cases].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1969, Volume: 54, Issue:3

    Topics: Animals; Animals, Newborn; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Fetal Diseases; Liver; Methylprednisolone; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Rats

1969