methylprednisolone has been researched along with Brain Injuries in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (41.18) | 18.7374 |
| 1990's | 13 (25.49) | 18.2507 |
| 2000's | 6 (11.76) | 29.6817 |
| 2010's | 10 (19.61) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Atz, AM; Bradley, SM; Everett, AD; Graham, EM; Hamlin-Smith, K; Kavarana, MN; Mahle, WT; Martin, RH; Shipes, VB; Zyblewski, SC | 1 |
| Chen, X; Cheng, C; Dai, Y; Hu, X; Jiang, Y; Kang, Z; Lu, Z; Peng, F | 1 |
| Tan, B; Teng, P | 1 |
| Chai, Y; Chen, X; Dong, J; Jiang, R; Luo, L; Zhang, J; Zhao, Z | 1 |
| Asehnoune, K; Cinotti, R; Roquilly, A; Vourc'h, M | 1 |
| Borruat, FX; Kardon, RH; Maeder, P; Meier, PG | 1 |
| Chen, X; Dong, JF; Yang, SY; Zhang, JN; Zhang, KL | 1 |
| Acciai, C; Carpinteri, F; Falsetti, P; Lenzi, L; Palilla, R; Patrizio, C | 1 |
| Chai, Y; Chen, X; Dong, B; Jiang, R; Lei, P; Zhang, B; Zhang, J | 1 |
| Chen, X; Dayao, C; Jiang, R; Lin, Y; Liu, L; Tan, T; Yang, Z; Zhang, B; Zhang, J | 1 |
| Lingsma, HF; Maas, AI; Perel, P; Roberts, I; Roozenbeek, B; Steyerberg, EW | 1 |
| Arikok, AT; Ergil, J; Ergüder, BI; Gürer, B; Hasturk, AE; Kanat, MA; Kertmen, H; Sekerci, Z; Yilmaz, ER | 1 |
| Faillace, WJ | 1 |
| SCIALABBA, DA; SHULMAN, K | 1 |
| COOK, AW; LIN, TH; SPARACIO, RR | 1 |
| Kamano, S | 1 |
| Misirlioglu, M; Ozisik, K; Ozisik, P; Tuncer, S; Yildirim, E | 1 |
| Demopoulos, HB; Flamm, ES; Mitamura, JA; Ransohoff, J; Seligman, ML; Solomon, JJ | 1 |
| Grau, H; Steudel, WI | 1 |
| Molofsky, WJ | 1 |
| Triggs, WJ; Willmore, LJ | 1 |
| Stolke, D | 1 |
| Carro, E; Ducker, TB; Salcman, M; Saul, TG | 1 |
| Eliasson, I; Grände, PO; Nilsson-Ehle, P; Roth, B | 1 |
| De Ley, L; Go, KG; Molenaar, WM; Parente, L; Solito, E; Ter Haar, JG; Zuiderveen, F | 1 |
| Chiang, YH; Chiou, TL; Lin, SZ; Song, WS | 1 |
| Hall, ED; McCall, JM; Means, ED | 1 |
| Hall, ED | 3 |
| Bullock, R | 1 |
| Cetinalp, E; Ildan, F; Isbir, T; Karadayi, A; Kaya, M; Oner, A; Polat, S | 1 |
| Frank, E; Nguyen, T; Trunkey, D | 1 |
| Park, CO | 1 |
| Bachratá, K; Horáková, L; Ondrejicková, O; Vajdová, M | 1 |
| Burmester, GR; Buttgereit, F; Fici, G; Schmid, D; Tripmacher, R; von Voigtlander, P | 1 |
| Dietz, H; Stolke, D; Weidner, A | 1 |
| Becker, DP; Gudeman, SK; Miller, JD | 1 |
| Ducker, TB; Itani, AL | 1 |
| Feuer, H | 1 |
| Braughler, JM; Hall, ED; McCall, JM | 2 |
| Anderson, DK; Andrus, PK; Cox, JW; Hall, ED; Yonkers, PA | 1 |
| Pappius, HM | 1 |
| Braughler, JM; Chase, RL; Hall, ED; McCall, JM; Yonkers, PA | 1 |
| Cerra, FB; Deutschman, CS; Konstantinides, FN; Raup, S | 1 |
| Ekström-Jodal, B; Larsson, LE | 1 |
| Braughler, JM; Hall, ED | 1 |
| Clifton, GL; Goodman, JC; Robertson, CS | 1 |
| Allegre, G; Bouvier, C; Dechaume, JP; Porta, JP; Thierry, A | 1 |
12 review(s) available for methylprednisolone and Brain Injuries
| Article | Year |
|---|---|
Management of childhood neurotrauma.
Topics: Algorithms; Brain Injuries; Child; Glucocorticoids; Humans; Intracranial Pressure; Methylprednisolone; Neuroprotective Agents; Spinal Cord Injuries | 2002 |
Are steroids really ineffective for severely head injured patients?
Topics: Brain Injuries; Craniocerebral Trauma; Dose-Response Relationship, Drug; Free Radicals; Glucocorticoids; Humans; Lipid Peroxidation; Methylprednisolone; Oxidative Stress; Spinal Cord Injuries; Treatment Outcome | 2000 |
Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Brain Ischemia; Humans; Lipid Peroxidation; Lipid Peroxides; Methylprednisolone; Pregnatrienes; Spinal Cord Injuries; Subarachnoid Hemorrhage | 1994 |
Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury.
Topics: Animals; Brain Injuries; Glucocorticoids; Humans; Lipid Peroxides; Methylprednisolone; Motor Neurons; Nerve Degeneration; Neurons; Pregnatrienes; Spinal Cord Injuries; Steroids | 1993 |
Steroids in central nervous system injury.
Topics: Adrenal Cortex Hormones; Animals; Brain Injuries; Humans; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Superoxide Dismutase | 1996 |
Early management of pediatric head injury. Physiologic aspects.
Topics: Brain Edema; Brain Injuries; Carbon Dioxide; Child; Craniocerebral Trauma; Dexamethasone; Glycerol; Humans; Hyponatremia; Infant; Infusions, Parenteral; Intracranial Pressure; Mannitol; Methylprednisolone; Pediatrics; Pulmonary Edema; Respiration; Water Intoxication | 1975 |
Antioxidant effects in brain and spinal cord injury.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain Injuries; Methylprednisolone; Spinal Cord Injuries; Steroids; Vitamin E | 1992 |
Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury.
Topics: Animals; Antioxidants; Brain Injuries; Free Radical Scavengers; Humans; Lipid Peroxidation; Lipid Peroxides; Methylprednisolone; Pregnatrienes; Spinal Cord Injuries; Steroids; Vitamin E | 1992 |
The neuroprotective pharmacology of methylprednisolone.
Topics: Animals; Brain Injuries; Cerebrovascular Disorders; Humans; Methylprednisolone; Spinal Cord Injuries | 1992 |
Steroids after spinal cord injury.
Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors | 1990 |
The therapeutic effects of drugs in injured central nervous system.
Topics: Brain Injuries; Dexamethasone; Disease Models, Animal; Glucose; Humans; Methylprednisolone; Neurotransmitter Agents; Prostaglandins; Spinal Cord Injuries | 1985 |
Cerebral effects of HDC.
Topics: Adrenal Cortex Hormones; Animals; Blood-Brain Barrier; Brain Diseases; Brain Edema; Brain Injuries; Brain Ischemia; Brain Neoplasms; Cerebral Hemorrhage; Cerebral Infarction; Cerebrovascular Circulation; Dexamethasone; Dogs; Humans; Methylprednisolone; Oxygen Consumption; Shock, Septic | 1985 |
5 trial(s) available for methylprednisolone and Brain Injuries
| Article | Year |
|---|---|
Intraoperative Methylprednisolone and Neurodevelopmental Outcomes in Infants After Cardiac Surgery.
Topics: Biomarkers; Brain Injuries; Cardiac Surgical Procedures; Humans; Infant; Infant, Newborn; Methylprednisolone; Neurodevelopmental Disorders; Prognosis | 2022 |
Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injury.
Topics: Adrenal Cortex Hormones; Adult; Brain Injuries; Evidence-Based Medicine; Female; Hospital Mortality; Humans; Logistic Models; Male; Methylprednisolone; Middle Aged; Odds Ratio; Reproducibility of Results; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Young Adult | 2011 |
[Effect of methylprednisolone and dexamethasone on the prognosis and EEG in severe craniocerebral injuries].
Topics: Adolescent; Adult; Brain Edema; Brain Injuries; Dexamethasone; Electroencephalography; Evoked Potentials; Female; Humans; Male; Methylprednisolone; Prognosis; Tomography, X-Ray Computed | 1984 |
Steroids in severe head injury: A prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Brain Injuries; Clinical Trials as Topic; Humans; Intracranial Pressure; Methylprednisolone; Middle Aged; Prospective Studies; Random Allocation; Steroids | 1981 |
Steroids after spinal cord injury.
Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors | 1990 |
35 other study(ies) available for methylprednisolone and Brain Injuries
| Article | Year |
|---|---|
Clinical, radiographic characteristics and immunomodulating changes in neuromyelitis optica with extensive brain lesions.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Aquaporin 4; Brain; Brain Injuries; C-Reactive Protein; Chi-Square Distribution; Complement System Proteins; Diffusion Tensor Imaging; Disability Evaluation; Female; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Neuromyelitis Optica; Oligoclonal Bands; Retrospective Studies | 2013 |
Carbamazepine-induced DRESS syndrome in a child: rapid response to pulsed corticosteroids.
Topics: Adolescent; Anti-Inflammatory Agents; Anticonvulsants; Brain Injuries; Carbamazepine; Drug Hypersensitivity Syndrome; Drug Therapy, Combination; Emollients; Fluocinolone Acetonide; Hepatomegaly; Humans; Male; Methylprednisolone; Mineral Oil; Pulse Therapy, Drug; Seizures; Skin; Ursodeoxycholic Acid | 2013 |
Stress-dose hydrocortisone reduces critical illness-related corticosteroid insufficiency associated with severe traumatic brain injury in rats.
Topics: Adrenal Cortex Hormones; Animals; Apoptosis; Blood-Brain Barrier; Brain Injuries; Critical Illness; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Hydrocortisone; Hypothalamus; Immunohistochemistry; In Situ Nick-End Labeling; Male; Methylprednisolone; Rats; Rats, Wistar; Tight Junctions | 2013 |
A new way of thinking: hydrocortisone in traumatic brain-injured patients.
Topics: Adrenal Cortex Hormones; Animals; Brain Injuries; Critical Illness; Hydrocortisone; Male; Methylprednisolone | 2013 |
Homonymous Ganglion Cell Layer Thinning After Isolated Occipital Lesion: Macular OCT Demonstrates Transsynaptic Retrograde Retinal Degeneration.
Topics: Anti-Inflammatory Agents; Brain Injuries; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Nerve Fibers; Occipital Lobe; Retinal Degeneration; Retinal Ganglion Cells; Tomography, Optical Coherence; Tomography, X-Ray Computed; Visual Pathways | 2015 |
Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats.
Topics: Amnesia, Retrograde; Animals; Apoptosis; Brain Injuries; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hippocampus; In Situ Nick-End Labeling; Male; Maze Learning; Methylprednisolone; Rats; Rats, Wistar; Space Perception | 2009 |
Bedside ultrasound in early diagnosis of neurogenic heterotopic ossification in patients with acquired brain injury.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Brain Injuries; Etidronic Acid; Female; Hip; Humans; Indomethacin; Male; Methylprednisolone; Middle Aged; Ossification, Heterotopic; Point-of-Care Systems; Radionuclide Imaging; Treatment Outcome; Ultrasonography, Doppler; Vascular Resistance | 2011 |
Methylprednisolone exacerbates acute critical illness-related corticosteroid insufficiency associated with traumatic brain injury in rats.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Animals; Apoptosis; Brain Injuries; Critical Illness; Disease Models, Animal; Glucocorticoids; Hypothalamo-Hypophyseal System; Male; Methylprednisolone; Mice; Nerve Degeneration; Rats; Rats, Wistar | 2011 |
Impairment of synaptic plasticity in hippocampus is exacerbated by methylprednisolone in a rat model of traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; CA3 Region, Hippocampal; Dentate Gyrus; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Methylprednisolone; Nerve Degeneration; Neuronal Plasticity; Rats; Rats, Wistar | 2011 |
The protective effect of 2-mercaptoethane sulfonate (MESNA) against traumatic brain injury in rats.
Topics: Animals; Apoptosis; Brain Injuries; Disease Models, Animal; Lipid Peroxidation; Male; Mesna; Methylprednisolone; Oxidative Stress; Protective Agents; Rats; Rats, Wistar | 2013 |
USE OF STEROIDS IN CLINICAL AND EXPERIMENTAL CEREBRAL EDEMA.
Topics: Brain Edema; Brain Injuries; Dogs; Edema; Methylprednisolone; Nitrogen; Pharmacology; Research; Steroids | 1964 |
METHYLPREDNISOLONE SODIUM SUCCINATE IN ACUTE CRANIOCEREBRAL TRAUMA.
Topics: Brain Injuries; Craniocerebral Trauma; Decerebrate State; Drug Therapy; Hematoma; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Mortality; Prognosis; Toxicology | 1965 |
Expression of antiapoptotic survivin and aven genes in rat heart tissue after traumatic brain injury.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Brain Injuries; DNA Primers; DNA, Complementary; Erythropoietin; Gene Expression Regulation; Heart; Methylprednisolone; Microtubule-Associated Proteins; Muscle Cells; Polymerase Chain Reaction; Rats; RNA; Survivin | 2006 |
Loss of essential membrane lipids and ascorbic acid from rat brain following cryogenic injury and protection by methylprednisolone.
Topics: Animals; Ascorbic Acid; Brain; Brain Edema; Brain Injuries; Cholesterol; Fatty Acids, Unsaturated; Free Radicals; Freezing; Membrane Lipids; Methylprednisolone; Phospholipids; Rats; Rats, Inbred Strains | 1981 |
Steroids and head trauma.
Topics: Brain Injuries; Dexamethasone; Dose-Response Relationship, Drug; Humans; Intracranial Pressure; Methylprednisolone; Neuropsychological Tests; Prognosis; Steroids | 1984 |
Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy.
Topics: Animals; Brain Injuries; Chlorides; Electroencephalography; Epilepsy; Ferric Compounds; Lipid Peroxides; Male; Methylprednisolone; Phenytoin; Rats; Rats, Inbred Strains | 1984 |
[Steroids and experimental brain edema. Effect of the lysosomal enzymes of brain tissue on steroid treatment after local cold injury].
Topics: Animals; Arylsulfatases; Brain Edema; Brain Injuries; Cats; Cold Temperature; Glucuronidase; Hexosaminidases; Lysosomes; Methylprednisolone | 1983 |
Possible role of short-term parenteral nutrition with fat emulsions for development of haemophagocytosis with multiple organ failure in a patient with traumatic brain injury.
Topics: Adult; Alanine Transaminase; Amylases; Brain Injuries; C-Reactive Protein; Creatinine; Fat Emulsions, Intravenous; Female; Fever; Histiocytosis, Non-Langerhans-Cell; Humans; Leukocyte Count; Methylprednisolone; Multiple Organ Failure; Partial Thromboplastin Time; Triglycerides | 1993 |
Effect of steroids on brain lipocortin immunoreactivity.
Topics: Animals; Annexin A1; Annexin A2; Annexin A5; Annexins; Antioxidants; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral Infarction; Immunoenzyme Techniques; Methylprednisolone; Microglia; Neuroglia; Neurons; Pregnatrienes; Rats; Rats, Wistar | 1994 |
Combined treatment with nicardipine, phenobarbital, and methylprednisolone ameliorates vasogenic brain edema.
Topics: Animals; Blood Proteins; Blood-Brain Barrier; Brain Edema; Brain Injuries; Drug Therapy, Combination; Evans Blue; Free Radicals; Injections, Intraperitoneal; Inulin; Lipid Peroxidation; Methylprednisolone; Nicardipine; Parietal Lobe; Phenobarbital; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance | 1994 |
Opportunities for neuroprotective drugs in clinical management of head injury.
Topics: Animals; Brain Chemistry; Brain Injuries; Cardiovascular Agents; Diuretics; Drug Therapy, Combination; Growth Substances; Hematoma, Subdural; Humans; Hypnotics and Sedatives; Intracranial Pressure; Methylprednisolone; Rats | 1993 |
The effect of the treatment of high-dose methylprednisolone on Na(+)-K(+)/Mg(+2) ATPase activity and lipid peroxidation and ultrastructural findings following cerebral contusion in rat.
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Injuries; Ca(2+) Mg(2+)-ATPase; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Methylprednisolone; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 1995 |
The effects of methylprednisolone on prevention of brain edema after experimental moderate diffuse brain injury in rats--comparison between dosage, injection time, and treatment methods.
Topics: Animals; Brain Edema; Brain Injuries; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 1998 |
Preventive effect of several antioxidants after oxidative stress on rat brain homogenates.
Topics: Animals; Antioxidants; Benzenesulfonates; Brain; Brain Injuries; Butylated Hydroxytoluene; Carbolines; Chromans; Creatine Kinase; Cyclic N-Oxides; Inhibitory Concentration 50; Lipid Peroxidation; Male; Melatonin; Methylprednisolone; Models, Chemical; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Oxygen; Pregnatrienes; Rats; Rats, Wistar; Serotonin; Thiobarbituric Acid Reactive Substances | 2000 |
Short-term effects of the 21-aminosteroid lazaroid tirilazad mesylate (PNU-74006F) and the pyrrolopyrimidine lazaroid PNU-101033E on energy metabolism of human peripheral blood mononuclear cells.
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Brain Injuries; Calcium-Transporting ATPases; Cell Membrane; Cell Respiration; Concanavalin A; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Protein Biosynthesis; Proteins; Pyrimidines; Pyrroles; Sodium-Potassium-Exchanging ATPase; Time Factors | 2001 |
Steroid treatment after cold lesion of the cat brain and its influence on lysosomal enzymes.
Topics: Animals; Brain; Brain Injuries; Cats; Dominance, Cerebral; Glucuronidase; Lysosomes; Methylprednisolone | 1979 |
Failure of high-dose steroid therapy to influence intracranial pressure in patients with severe head injury.
Topics: Adolescent; Adult; Aged; Brain Injuries; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Intracranial Pressure; Male; Methylprednisolone; Middle Aged | 1979 |
Effect of high and low doses of steroids on head injuries.
Topics: Animals; Brain Edema; Brain Injuries; Female; Haplorhini; Humans; Male; Methylprednisolone; Time Factors | 1976 |
A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Brain; Brain Injuries; Cells, Cultured; gamma-Aminobutyric Acid; Lipid Peroxides; Male; Methylprednisolone; Mice; Organ Size; Pituitary Gland; Prednisone; Synaptic Membranes; Synaptosomes; Thymus Gland | 1987 |
A new class of compounds for stroke and trauma: effects of 21-aminosteroids on lipid peroxidation.
Topics: Animals; Azasteroids; Brain Injuries; Chemical Phenomena; Chemistry; Free Radicals; Lipid Peroxides; Methylprednisolone; Oxygen; Steroids, Heterocyclic | 1987 |
Physiological and metabolic response to isolated closed-head injury. Part 2: Effects of steroids on metabolism. Potentiation of protein wasting and abnormalities of substrate utilization.
Topics: Adult; Aged; Amino Acids; Blood Glucose; Brain Injuries; Female; Humans; Longitudinal Studies; Male; Methylprednisolone; Proteins; Triglycerides | 1987 |
Current application of "high-dose" steroid therapy for CNS injury. A pharmacological perspective.
Topics: Brain Injuries; Dexamethasone; Glucocorticoids; Humans; Methylprednisolone; Spinal Cord Injuries | 1985 |
High-dose glucocorticoid treatment improves neurological recovery in head-injured mice.
Topics: Animals; Brain Injuries; Chemical Phenomena; Chemistry; Glucocorticoids; Hydrocortisone; Male; Methylprednisolone; Mice; Mice, Inbred Strains; Prednisolone | 1985 |
Steroid administration and nitrogen excretion in the head-injured patient.
Topics: Adult; Brain Injuries; Female; Humans; Male; Metabolic Clearance Rate; Methylprednisolone; Middle Aged; Nitrogen | 1985 |
[Use of sodium methyl-6-prednisolone hemisuccinate (Solumedrol) in the treatment of intracranial hypertension and various severe neurologic states].
Topics: Brain Diseases; Brain Edema; Brain Injuries; Brain Neoplasms; Cerebrovascular Disorders; Humans; Intracranial Pressure; Methylprednisolone; Succinates | 1971 |