methylprednisolone and Allergic Encephalomyelitis

methylprednisolone has been researched along with Allergic Encephalomyelitis in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.13)18.7374
1990's2 (6.45)18.2507
2000's10 (32.26)29.6817
2010's12 (38.71)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Bárcena, B; Besedovsky, HO; Espinosa, A; Fragoso, G; Meneses, G; Peón, AN; Pérez-Osorio, IN; Rassy, D; Sciutto, E; Terrazas, LI1
Li, G; Li, H; Ma, Z; Wang, M; Wang, XY; Wang, Z; Yi, H; Zheng, G1
Dokoohaki, S; Farhadi, N; Ghanbari, A; Ghareghani, M; Sadeghi, H; Zibara, K1
Jeun, SS; Kim, MJ; Kim, WS; Lim, JY; Park, SA; Park, SI; Ryu, CH1
Blaževski, J; Jevtic, B; Miljković, D; Momčilović, M; Mostarica Stojković, M; Petković, F1
Dai, YQ; Hu, XQ; Lu, ZQ; Qiu, W; Ruan, HF; Shu, YQ; Wang, YG; Wu, AM; Xiao, L; Yang, Y1
Bi, J; Liu, Z; Wang, C; Wang, P; Xie, Z; You, W; Zhu, Z1
Appeldoorn, CC; Gaillard, PJ; Gladdines, W; Lee, DH; Linker, RA; Reijerkerk, A; Rötger, C1
Dokoohaki, S; Farhadi, N; Ghanbari, A; Ghareghani, M; Hosseini, SM; Mohammadi, R; Sadeghi, H1
Bähr, M; Graf, I; Hein, K; Herold, S; Jung, K; Kumar, P; Menkhoff, H; Schulz, X1
Alderuccio, F; Ban, EJ; Bernard, C; Chan, J; Chun, KH; McQualter, J; Toh, BH; Wang, S1
Dutt, M; Rostami, A; Shindler, KS; Tabuena, P; Ventura, E1
Miljković, D; Miljković, Z; Momcilović, M; Mostarica-Stojković, M1
Chen, X; Hu, X; Jiang, Y; Liu, M; Liu, Y; Ma, X; Mao, X; Pi, R1
Hong, MF; Huang, YQ; Jie, A; Peng, ZX; Su, QX; Wang, R; Wang, XH; Wei, ZS; Yu, QY; Zhang, MX1
Appeldoorn, CC; de Vries, HE; Dorland, R; Gaillard, PJ; Kooij, G; Reijerkerk, A; Rip, J; van der Pol, SM1
Bähr, M; Diem, R; Hobom, M; Maier, K; Meyer, R; Storch, MK; Weissert, R1
KIBLER, RF2
Butovsky, O; Hauben, E; Ibarra, A; Schwartz, M1
Bähr, M; Demmer, I; Diem, R; Ehrenreich, H; Maier, K; Merkler, D; Sättler, MB; Stadelmann, C1
Becker, G; Briel, A; Gold, R; Hauff, P; Linker, RA; Mäurer, M; Reinhardt, M; Rieckmann, P; Schirner, M; Toyka, KV1
Bendszus, M; Briel, A; Hauff, P; Ladewig, G; Linker, RA; Mäurer, M; Reinhardt, M; Schirner, M1
Gold, R; Knauth, M; Linker, RA; Lühder, F; Metselaar, JM; Mohr, A; Schmidt, J; Weller, C1
Dijkstra, CD; Polman, CH; Sontrop, K; Uitdehaag, BM1
Gold, R; Hartung, HP; Schmidt, J; Schönrock, L; Toyka, KV; Zettl, UK1
Gold, R; Schmidt, J; Stürzebecher, S; Toyka, KV1
Abramsky, O; Brenner, T; Mizrachi-Kol, R; Steiner, I1
Kowalczyk-Bronisz, SH1
Kibler, RF; Paty, DW; Vogel, C1
Abrahamson, HA1

Other Studies

31 other study(ies) available for methylprednisolone and Allergic Encephalomyelitis

ArticleYear
Intranasal Methylprednisolone Effectively Reduces Neuroinflammation in Mice With Experimental Autoimmune Encephalitis.
    Journal of neuropathology and experimental neurology, 2020, 02-01, Volume: 79, Issue:2

    Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation Mediators; Lymphocytes; Macrophages; Methylprednisolone; Mice, Inbred C57BL; Microglia; Spinal Cord

2020
Methylprednisolone alleviates multiple sclerosis by expanding myeloid-derived suppressor cells via glucocorticoid receptor β and S100A8/9 up-regulation.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:23

    Topics: Animals; Arginase; Biomarkers; Calgranulin A; Calgranulin B; Disease Models, Animal; Disease Susceptibility; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Humans; Immunophenotyping; Leukocytes, Mononuclear; Methylprednisolone; Mice; Multiple Sclerosis; Myeloid-Derived Suppressor Cells; Receptors, Glucocorticoid; T-Lymphocytes

2020
Corticosteroid therapy exacerbates the reduction of melatonin in multiple sclerosis.
    Steroids, 2017, Volume: 128

    Topics: Adrenal Cortex Hormones; Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Interferon-gamma; Interleukin-4; Melatonin; Methylprednisolone; Multiple Sclerosis; Rats; Th1 Cells; Th2 Cells

2017
Effective combination of methylprednisolone and interferon β-secreting mesenchymal stem cells in a model of multiple sclerosis.
    Journal of neuroimmunology, 2018, 01-15, Volume: 314

    Topics: Animals; Anti-Inflammatory Agents; Encephalomyelitis, Autoimmune, Experimental; Female; Genetic Therapy; Humans; Interferon-beta; Mesenchymal Stem Cell Transplantation; Methylprednisolone; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Spinal Cord

2018
High interleukin-10 expression within the central nervous system may be important for initiation of recovery of Dark Agouti rats from experimental autoimmune encephalomyelitis.
    Immunobiology, 2013, Volume: 218, Issue:9

    Topics: Animals; Astrocytes; Cells, Cultured; Chemokine CXCL12; Convalescence; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Interleukin-10; Methylprednisolone; Rats; Rats, Inbred Strains; Spinal Cord; Transforming Growth Factor beta

2013
Combined therapy with methylprednisolone and ulinastatin in experimental autoimmune encephalomyelitis.
    Chinese medical journal, 2013, Volume: 126, Issue:18

    Topics: Animals; Drug Combinations; Encephalomyelitis, Autoimmune, Experimental; Female; Glycoproteins; Methylprednisolone; Mice; Mice, Inbred C57BL; Multiple Sclerosis

2013
Mycophenolate mofetil improves neurological function and alters blood T-lymphocyte subsets in rats with experimental autoimmune encephalomyelitis.
    The Journal of international medical research, 2014, Volume: 42, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Guinea Pigs; Immunosuppressive Agents; IMP Dehydrogenase; Interleukin-2 Receptor alpha Subunit; Leukocyte Common Antigens; Lymphocyte Count; Methylprednisolone; Multiple Sclerosis; Mycophenolic Acid; Random Allocation; Rats; Rats, Wistar; T-Lymphocyte Subsets

2014
Glutathione PEGylated liposomal methylprednisolone (2B3-201) attenuates CNS inflammation and degeneration in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 2014, Sep-15, Volume: 274, Issue:1-2

    Topics: Animals; Astrocytes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Liposomes; Macrophages; Methylprednisolone; Mice; Mice, Inbred C57BL; Multiple Sclerosis, Relapsing-Remitting; Myelin-Oligodendrocyte Glycoprotein; Polyethylene Glycols; Spinal Cord; T-Lymphocytes

2014
Methylprednisolone improves lactate metabolism through reduction of elevated serum lactate in rat model of multiple sclerosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Lactic Acid; Methylprednisolone; Multiple Sclerosis; Rats; Rats, Inbred Lew

2016
CatWalk gait analysis in a rat model of multiple sclerosis.
    BMC neuroscience, 2016, 11-30, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Area Under Curve; Automation, Laboratory; Biomechanical Phenomena; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Functional Laterality; Gait; Immunohistochemistry; Logistic Models; Methylprednisolone; Random Allocation; Rats; Spinal Cord

2016
Methylprednisolone induces reversible clinical and pathological remission and loss of lymphocyte reactivity to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis.
    Autoimmunity, 2008, Volume: 41, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Brain; Cell Proliferation; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Lymphocyte Activation; Methylprednisolone; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Remission Induction; Spinal Cord

2008
Timing of corticosteroid therapy is critical to prevent retinal ganglion cell loss in experimental optic neuritis.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:3

    Topics: Animals; Cell Count; Cell Survival; Dexamethasone; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorescent Dyes; Glucocorticoids; Methylprednisolone; Mice; Optic Neuritis; Retinal Ganglion Cells; Stilbamidines; Time Factors

2010
Methylprednisolone inhibits IFN-gamma and IL-17 expression and production by cells infiltrating central nervous system in experimental autoimmune encephalomyelitis.
    Journal of neuroinflammation, 2009, Dec-11, Volume: 6

    Topics: Animals; Antigens, CD; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Glucocorticoids; Hormone Antagonists; Interferon-gamma; Interleukin-17; Methylprednisolone; Mifepristone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid

2009
Combination of methylprednisolone and minocycline synergistically improves experimental autoimmune encephalomyelitis in C57 BL/6 mice.
    Journal of neuroimmunology, 2010, Sep-14, Volume: 226, Issue:1-2

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Freund's Adjuvant; Glycoproteins; Interferon-gamma; Interleukin-4; Methylprednisolone; Mice; Mice, Inbred C57BL; Minocycline; Myelin-Oligodendrocyte Glycoprotein; Nerve Growth Factor; Neuroprotective Agents; Peptide Fragments; RNA, Messenger

2010
Super-high-dose methylprednisolone does not improve efficacy or induce glucocorticoid resistance in experimental allergic encephalomyelitis.
    Neuroimmunomodulation, 2011, Volume: 18, Issue:1

    Topics: Animals; Cytokines; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Resistance; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Male; Methylprednisolone; Nuclear Proteins; Protein Isoforms; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Treatment Outcome

2011
Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Dec-28, Volume: 164, Issue:3

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Brain; Drug Carriers; Encephalomyelitis, Autoimmune, Experimental; Glutathione; Liposomes; Male; Methylprednisolone; Polyethylene Glycols; Rats; Rats, Inbred Lew; Tissue Distribution

2012
Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Aug-06, Volume: 23, Issue:18

    Topics: Animals; Apoptosis; Blotting, Western; Calcium; Calcium Channels; Cell Count; Cell Survival; Central Nervous System; Disease Models, Animal; Electroretinography; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Evoked Potentials, Visual; Female; Methylprednisolone; Mitogen-Activated Protein Kinases; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neurons; Optic Neuritis; Phosphorylation; Rats; Rats, Inbred BN; Retinal Ganglion Cells; Signal Transduction

2003
INTRODUCTORY REMARKS: SUPPRESSION OF DEMYELINATING DISEASE.
    Annals of the New York Academy of Sciences, 1965, Mar-31, Volume: 122

    Topics: Demyelinating Diseases; Encephalomyelitis; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Methylprednisolone; Pharmacology

1965
LARGE DOSE CORTICOSTEROID THERAPY OF EXPERIMENTAL AND HUMAN DEMYELINATING DISEASES.
    Annals of the New York Academy of Sciences, 1965, Mar-31, Volume: 122

    Topics: Adrenal Cortex Hormones; Animals; Demyelinating Diseases; Drug Therapy; Encephalomyelitis; Encephalomyelitis, Autoimmune, Experimental; Humans; Methylprednisolone; Multiple Sclerosis; Prednisone; Rabbits

1965
The therapeutic window after spinal cord injury can accommodate T cell-based vaccination and methylprednisolone in rats.
    The European journal of neuroscience, 2004, Volume: 19, Issue:11

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Division; Cells, Cultured; Dextrans; Ectodysplasins; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Immunotherapy, Active; Laminectomy; Membrane Proteins; Methylprednisolone; Motor Activity; Mycobacterium; Myelin Basic Protein; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rhodamines; Species Specificity; Spinal Cord Injuries; T-Lymphocytes; Time Factors; Tryptophan

2004
Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 2

    Topics: Animals; Drug Therapy, Combination; Electroretinography; Encephalomyelitis, Autoimmune, Experimental; Erythropoietin; Evoked Potentials, Visual; Female; Methylprednisolone; Multiple Sclerosis; Neuroprotective Agents; Optic Nerve; Optic Neuritis; Rats; Rats, Inbred BN; Recombinant Proteins; Retinal Ganglion Cells; Signal Transduction

2005
Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by Sensitive Particle Acoustic Quantification (SPAQ).
    NeuroImage, 2005, Aug-15, Volume: 27, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain; Brain Chemistry; Cell Adhesion Molecules; Encephalomyelitis, Autoimmune, Experimental; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Intercellular Adhesion Molecule-1; Methylprednisolone; Microspheres; Rats; Rats, Inbred Lew; Spinal Cord; Ultrasonography, Doppler, Transcranial; Vascular Cell Adhesion Molecule-1

2005
In vivo molecular imaging of adhesion molecules in experimental autoimmune encephalomyelitis (EAE).
    Journal of autoimmunity, 2005, Volume: 25, Issue:3

    Topics: Animals; Brain; Densitometry; Encephalomyelitis, Autoimmune, Experimental; Female; Intercellular Adhesion Molecule-1; Magnetic Resonance Imaging; Methylprednisolone; Rats; Rats, Inbred Lew; Ultrasonography

2005
Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: long-term protective effects and enhanced efficacy of methylprednisolone formulations.
    Experimental neurology, 2008, Volume: 211, Issue:2

    Topics: Animals; Chemistry, Pharmaceutical; Encephalomyelitis, Autoimmune, Experimental; Female; Glucocorticoids; Liposomes; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Inbred Lew; Time; Treatment Outcome

2008
The effect of the 21-aminosteroid U74006F on the clinical course of acute experimental allergic encephalomyelitis.
    Journal of the neurological sciences, 1996, Volume: 135, Issue:1

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Male; Methylprednisolone; Pregnatrienes; Rats; Rats, Inbred Lew

1996
T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy.
    Brain : a journal of neurology, 2000, Volume: 123 ( Pt 7)

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cells, Cultured; Chromatography, High Pressure Liquid; Encephalomyelitis, Autoimmune, Experimental; Estrogens; Female; Immunohistochemistry; Methylprednisolone; Oligodendroglia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred Lew; Spinal Cord; T-Lymphocytes

2000
Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration.
    Journal of neuroscience research, 2001, Jul-01, Volume: 65, Issue:1

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Immunologic Factors; Interferon-beta; Macrophages; Methylprednisolone; Multiple Sclerosis, Relapsing-Remitting; Neuroprotective Agents; Rats; Rats, Inbred Lew; T-Lymphocytes; Tumor Necrosis Factor-alpha

2001
Development of experimental allergic encephalomyelitis during steroid administration. Outcome of neurological immune-mediated disorders under immunosuppressive therapy.
    Israel journal of medical sciences, 1991, Volume: 27, Issue:7

    Topics: Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Incidence; Methylprednisolone; Rats; Severity of Illness Index

1991
Glucosteroids in immunologically specific and nonspecific inflammatory processes.
    Archivum immunologiae et therapiae experimentalis, 1972, Volume: 20, Issue:4

    Topics: Adrenalectomy; Animals; Arthritis; Benzene; Blood Cell Count; Brain; Carrageenan; Dermatitis, Contact; Encephalomyelitis, Autoimmune, Experimental; Freund's Adjuvant; Glucocorticoids; Graft Rejection; Hydrocortisone; Hypersensitivity, Delayed; Immunization, Secondary; Inflammation; Lymph Nodes; Lymphocyte Activation; Methylprednisolone; Metyrapone; Nerve Tissue; Rats; Skin Transplantation; Tuberculin Test; Xylenes

1972
Treatment of experimental allergic encephalomyelitis in the rabbit.
    Archives of neurology, 1972, Volume: 26, Issue:4

    Topics: Animals; Cyclophosphamide; Drug Synergism; Encephalomyelitis, Autoimmune, Experimental; Evaluation Studies as Topic; Female; Immunosuppression Therapy; Methylprednisolone; Rabbits; Time Factors

1972
Prevention of experimental allergic encephalomyelitis with cobra venom factor.
    The Journal of asthma research, 1971, Volume: 8, Issue:4

    Topics: Animals; Cyclophosphamide; Encephalomyelitis, Autoimmune, Experimental; Humans; Hypersensitivity, Delayed; Methylprednisolone; Multiple Sclerosis; Rabbits; Rats; Snakes; Species Specificity; Venoms

1971