Page last updated: 2024-11-07

methylprednisolone acetate and Pain, Postoperative

methylprednisolone acetate has been researched along with Pain, Postoperative in 11 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"All cases showed an osteophyte within the popliteus sulcus of the lateral femoral condyle impinging on the adjacent tendon."1.48Ultrasound Diagnosis of Osteophytic Impingement of the Popliteus Tendon After Total Knee Replacement. ( Geannette, C; Mayman, D; Miller, TT; Sahr, M, 2018)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geannette, C1
Sahr, M1
Mayman, D1
Miller, TT1
Christensen, CP1
Jacobs, CA1
Jennings, HR1
Joo, JH1
Park, JW1
Kim, JS1
Kim, YH1
Debi, R1
Halperin, N1
Mirovsky, Y1
Lundin, A1
Magnuson, A1
Axelsson, K1
Kogler, H1
Samuelsson, L1
Mason, JO1
Katz, B1
Greene, HH1
Modi, H1
Chung, KJ1
Yoon, HS1
Yoo, HS1
Yoo, JH1
Erdemir, H1
Mann, K1
Gelman, S1
Glasser, RS1
Knego, RS1
Delashaw, JB1
Fessler, RG1
Lavyne, MH1
Bilsky, MH1
Mitchell, DA1
Ward-Booth, P1
Seymour, RA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Peri-articular Injections Containing a Corticosteroid During Total Knee Arthroplasty[NCT00492973]101 participants (Actual)Interventional2006-03-31Completed
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy for Herniated Lumbar Discs Is There a Role? - A Randomized Control Trial[NCT04182997]Phase 4200 participants (Anticipated)Interventional2019-11-21Recruiting
Effects of Intraoperative Local Steroid Utilization in a Single-Level Minimally Invasive Transforaminal Lumbar Interbody Fusion[NCT03308084]Phase 3105 participants (Actual)Interventional2015-11-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Amount of Pain Medication Taken Per Day

(NCT00492973)
Timeframe: Average of 3 days after surgery

Interventionmg/day morphine equivalant (Mean)
Control Group47.8
Corticosteroid46.0

Complications, Such as Infections, Hospital Readmissions, Manipulations Under Anesthesia, Etc.

(NCT00492973)
Timeframe: any point during the first postoperative year

InterventionNumber of participants with complication (Number)
Control Group0
Corticosteroid3

Knee Range of Motion

(NCT00492973)
Timeframe: 3 months

Interventiondegrees (Mean)
Control Group112.5
Corticosteroid112.4

Knee Society Scores

The Knee Society Score is on a scale of 0 to 100, with 0 being the worst possible score, and 100 being the best possible score. The Knee Society Score takes into account subjective patient reports of pain and functional ability as well as clinical measures of passive knee range of motion. (NCT00492973)
Timeframe: 3 months postoperative

Interventionunits on a scale (Mean)
Control Group87.1
Corticosteroid83.3

Length of Hospital Stay

(NCT00492973)
Timeframe: days after surgery

Interventiondays (Mean)
Control Group3.5
Corticosteroid2.6

Trials

7 trials available for methylprednisolone acetate and Pain, Postoperative

ArticleYear
Effect of periarticular corticosteroid injections during total knee arthroplasty. A double-blind randomized trial.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthroplasty, Replacemen

2009
Is intra-articular multimodal drug injection effective in pain management after total knee arthroplasty? A randomized, double-blinded, prospective study.
    The Journal of arthroplasty, 2011, Volume: 26, Issue:7

    Topics: Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Anti

2011
Local application of steroids following lumbar discectomy.
    Journal of spinal disorders & techniques, 2002, Volume: 15, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Back Pain; Diskectomy; Female; Humans; Injections, Intralesional; I

2002
Local application of steroids following lumbar discectomy.
    Journal of spinal disorders & techniques, 2002, Volume: 15, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Back Pain; Diskectomy; Female; Humans; Injections, Intralesional; I

2002
Local application of steroids following lumbar discectomy.
    Journal of spinal disorders & techniques, 2002, Volume: 15, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Back Pain; Diskectomy; Female; Humans; Injections, Intralesional; I

2002
Local application of steroids following lumbar discectomy.
    Journal of spinal disorders & techniques, 2002, Volume: 15, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Back Pain; Diskectomy; Female; Humans; Injections, Intralesional; I

2002
The effect of perioperative corticosteroids on the outcome of microscopic lumbar disc surgery.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2003, Volume: 12, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Cicatrix; Disability Evaluation; Double-Blind Method; Female; Humans

2003
Local application of low-dose Depo-Medrol is effective in reducing immediate postoperative back pain.
    International orthopaedics, 2009, Volume: 33, Issue:3

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Case-Control Studies; Diskectomy; Dose-Res

2009
Epidural steroids, postoperative morbidity, and recovery in patients undergoing microsurgical lumbar discectomy.
    Journal of neurosurgery, 1992, Volume: 77, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Female; Humans; Injections, Epidural; Interverteb

1992
A comparative study of the efficacy of aspirin and an ibuprofen/codeine combination in patients treated pre-operatively with methylprednisolone acetate.
    British dental journal, 1985, Aug-10, Volume: 159, Issue:3

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Codeine; Double-Blin

1985

Other Studies

4 other studies available for methylprednisolone acetate and Pain, Postoperative

ArticleYear
Ultrasound Diagnosis of Osteophytic Impingement of the Popliteus Tendon After Total Knee Replacement.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2018, Volume: 37, Issue:9

    Topics: Aged; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; Female; Humans; Knee Joint; Male; M

2018
Severe ocular pain secondary to occipital neuralgia following vitrectomy surgery.
    Retina (Philadelphia, Pa.), 2004, Volume: 24, Issue:3

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cranial Nerves; Female; Humans; Mal

2004
Intradural and extradural corticosteroids for postlaminectomy syndrome.
    The Alabama journal of medical sciences, 1982, Volume: 19, Issue:2

    Topics: Humans; Injections, Spinal; Laminectomy; Methylprednisolone; Methylprednisolone Acetate; Pain, Posto

1982
The perioperative use of corticosteroids and bupivacaine in the management of lumbar disc disease.
    Journal of neurosurgery, 1993, Volume: 78, Issue:3

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bupivacaine; Drug Therapy, Combination; Humans; I

1993