methylprednisolone acetate has been researched along with Odontalgia in 2 studies
Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this prospective, randomized, double-blind study was to evaluate the pulpal concentrations of prostaglandin E2 (PGE2) and interleukin-8 (IL-8) in untreated teeth with irreversible pulpitis after the administration of an intraosseous injection of Depo-Medrol." | 5.10 | Effect of an intraosseous injection of depo-medrol on pulpal concentrations of PGE2 and IL-8 in untreated irreversible pulpitis. ( Beck, M; Gallatin, E; Isett, J; Padgett, D; Reader, A, 2003) |
| "The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis." | 5.09 | Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol. ( Beck, M; Gallatin, E; Nist, R; Reader, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isett, J | 1 |
| Reader, A | 2 |
| Gallatin, E | 2 |
| Beck, M | 2 |
| Padgett, D | 1 |
| Nist, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anesthetic Efficacy of 4% Buffered Lidocaine in Emergency Patients With Facial Swelling.[NCT01981772] | 88 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Patients will rate pain on a Heft-Parker visual analog scale during needle insertion, placement, and solution deposition phases of the anesthetic injection(s). Patients will also rate pain during the incision and dissection phases of the incision and drainage procedure. The number of millimeters along the scale are reported. No pain corresponded to 0 mm. Mild pain was defined as greater than 0 mm and less than or equal to 54 mm. Mild pain included the descriptors of faint, weak, and mild pain. Moderate pain was defined as greater than 54 mm and less than 114 mm and included the descriptor moderate. Severe pain was defined as equal to or greater than 114 mm up to and including 170 mm. Severe pain included the descriptors of strong, intense, and maximum possible." (NCT01981772)
Timeframe: during incision/drainage on Day 0
| Intervention | units on a scale (Mean) |
|---|---|
| Buffered Lidocaine | 69.3 |
| Nonbuffered Lidocaine | 59.2 |
"Patients will rate their level of satisfaction with the incision and drainage procedure using a visual analog scale. The scale ranges from not satisfied, to somewhat satisfied, to moderately satisfied, to completely satisfied. Not satisfied corresponded to 0 mm. Somewhat satisfied was defined as greater than 0 mm and less than or equal to 33 mm. Moderately satisfied was defined as greater than 33 mm and less than 66 mm. Completely satisfied was defined as equal to or greater than 66 mm. Measurements along the scale were collected and analyzed by randomization test." (NCT01981772)
Timeframe: immediately post-procedure on Day 0
| Intervention | units on a scale (Mean) |
|---|---|
| Buffered Lidocaine | 92.7 |
| Nonbuffered Lidocaine | 89.5 |
2 trials available for methylprednisolone acetate and Odontalgia
| Article | Year |
|---|---|
Effect of an intraosseous injection of depo-medrol on pulpal concentrations of PGE2 and IL-8 in untreated irreversible pulpitis.
Topics: Adult; Anti-Inflammatory Agents; Bone and Bones; Chi-Square Distribution; Dental Pulp; Dinoprostone; | 2003 |
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-I | 2000 |