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methylprednisolone acetate and Inflammation

methylprednisolone acetate has been researched along with Inflammation in 12 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"To determine the effects of sodium hyaluronate (HA) in combination with methylprednisolone acetate (MPA) on interleukin-1 (IL-1)-induced inflammation in equine articular cartilage pellets."3.73Effects of sodium hyaluronate and methylprednisolone acetate on proteoglycan metabolism in equine articular chondrocytes treated with interleukin-1. ( Byron, CR; Constable, PD; Kaufmann, KM; Pondenis, HC; Stewart, AA; Yates, AC, 2006)
"The effect of THS-201, a new intra-articular steroid, on inflammations was examined using acute, subacute and chronic experimental models, and the antiinflammatory action of THS-201 was compared with those of reference steroids such as triamcinolone acetonide (TA), methylprednisolone acetate (MPA), hydrocortisone acetate (HA) and halopredone (HP)."3.67[Anti-inflammatory effect of THS-201, a new intra-articular steroid]. ( Hashimoto, Y; Kiniwa, M; Masuda, H; Miyake, H; Yamamoto, N, 1986)
"Methylprednisolone acetate (MPA) has a long history of use in the treatment of sciatic pain and other neuropathic pain syndromes."2.50The effects of glucocorticoids on neuropathic pain: a review with emphasis on intrathecal methylprednisolone acetate delivery. ( Kalkman, CJ; Rijsdijk, M; van Wijck, AJ; Yaksh, TL, 2014)
"The initiation time of myoclonic seizures (ITMS), the initiation time of tonic-clonic seizures (ITTS), seizure duration (SD), and mortality rate (MR) were measured for 30 min."1.91Effects of Intracerebroventricular Injection of the Steroidal and Non-Steroidal Anti-Inflammatory Drugs on the Seizures during the Estrous Cycle in Rat. ( Fazlelahi, Z; Kaboutari, J; Panahi, N; Zendehdel, M, 2023)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Belacic, ZA1
Sullivan, SN1
Rice, HC1
Durgam, SS1
Fazlelahi, Z1
Kaboutari, J1
Zendehdel, M1
Panahi, N1
Trahan, RA1
Byron, CR2
Dahlgren, LA1
Pleasant, RS1
Werre, SR1
Rijsdijk, M1
van Wijck, AJ1
Kalkman, CJ1
Yaksh, TL1
Barton, KI1
Heard, BJ1
Chung, M1
Sevick, JL1
Martin, CR1
Achari, Y1
Frank, CB1
Shrive, NG1
Hart, DA1
Lundin, A1
Magnuson, A1
Axelsson, K1
Kogler, H1
Samuelsson, L1
Yates, AC1
Stewart, AA1
Pondenis, HC1
Kaufmann, KM1
Constable, PD1
Khalil, N1
Whitman, C1
Zuo, L1
Danielpour, D1
Greenberg, A1
Phillips, GD1
Whitehead, RA1
Knighton, DR1
Cicala, RS1
Turner, R1
Moran, E1
Henley, R1
Wong, R1
Evans, J1
Kiniwa, M1
Yamamoto, N1
Hashimoto, Y1
Miyake, H1
Masuda, H1

Reviews

1 review available for methylprednisolone acetate and Inflammation

ArticleYear
The effects of glucocorticoids on neuropathic pain: a review with emphasis on intrathecal methylprednisolone acetate delivery.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:5

    Topics: Anti-Inflammatory Agents; Drug Resistance; Female; Gene Expression; Glucocorticoids; Humans; Inflamm

2014

Trials

1 trial available for methylprednisolone acetate and Inflammation

ArticleYear
The effect of perioperative corticosteroids on the outcome of microscopic lumbar disc surgery.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2003, Volume: 12, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Cicatrix; Disability Evaluation; Double-Blind Method; Female; Humans

2003

Other Studies

10 other studies available for methylprednisolone acetate and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Interleukin-1β and methylprednisolone acetate demonstrate differential effects on equine deep digital flexor tendon and navicular bone fibrocartilage cells in vitro.
    American journal of veterinary research, 2023, Apr-01, Volume: 84, Issue:4

    Topics: Animals; Fibrocartilage; Horse Diseases; Horses; Inflammation; Interleukin-1beta; Methylprednisolone

2023
Effects of Intracerebroventricular Injection of the Steroidal and Non-Steroidal Anti-Inflammatory Drugs on the Seizures during the Estrous Cycle in Rat.
    Archives of Razi Institute, 2023, Volume: 78, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Estrous Cycle; Female; Inflammation; Ketorolac; Methylprednisolon

2023
In vitro effects of three equimolar concentrations of methylprednisolone acetate, triamcinolone acetonide, and isoflupredone acetate on equine articular tissue cocultures in an inflammatory environment.
    American journal of veterinary research, 2018, Volume: 79, Issue:9

    Topics: Animals; Cartilage, Articular; Coculture Techniques; Dinoprostone; Female; Fluprednisolone; Glycosam

2018
Location and gene-specific effects of methylprednisolone acetate on mitigating IL1β-induced inflammation in mature ovine explant knee tissue.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017, Volume: 66, Issue:3

    Topics: Adiponectin; Adipose Tissue; Animals; Cartilage, Articular; Cytokines; Female; Inflammation; Knee Jo

2017
Effects of sodium hyaluronate and methylprednisolone acetate on proteoglycan metabolism in equine articular chondrocytes treated with interleukin-1.
    American journal of veterinary research, 2006, Volume: 67, Issue:12

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Horses; Hy

2006
Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Animals; Bleomycin; Cells, Cultured; Culture Media, Conditioned; Dexamethasone; Escherichia coli; Fe

1993
Inhibition by methylprednisolone acetate suggests an indirect mechanism for TGF-B induced angiogenesis.
    Growth factors (Chur, Switzerland), 1992, Volume: 6, Issue:1

    Topics: Animals; Cornea; Drug Implants; Humans; Hydrogels; Inflammation; Methylprednisolone; Methylprednisol

1992
Methylprednisolone acetate does not cause inflammatory changes in the epidural space.
    Anesthesiology, 1990, Volume: 72, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Epidural Space; Inflammation; Injections, Epidural; Lidocaine; Me

1990
[Anti-inflammatory effect of THS-201, a new intra-articular steroid].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Flup

1986