Page last updated: 2024-11-07

methylprednisolone acetate and Fungal Meningitis

methylprednisolone acetate has been researched along with Fungal Meningitis in 17 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Research Excerpts

ExcerptRelevanceReference
"Fungal meningitis due to injections of contaminated methylprednisolone acetate can present with vascular sequelae in immunocompetent individuals."7.79Vascular complications of fungal meningitis attributed to injections of contaminated methylprednisolone acetate. ( Abel, T; Beck, A; Claassen, DO; Jones, P; Kleinfeld, K; Paueksakon, P; Riebau, D, 2013)
"The outbreak of fungal meningitis associated with contaminated methylprednisolone acetate has thrust the importance of fungal infections into the public consciousness."4.89Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans. ( Gauthier, GM; Keller, NP, 2013)
"The recent outbreak of fungal meningitis related to contaminated methylprednisolone acetate injections represents an important cause of morbidity and continues to be a significant public health problem in the United States."4.89Lessons learned in the multistate fungal infection outbreak in the United States. ( Pappas, PG, 2013)
"Exserohilum rostratum was the major cause of the multistate outbreak of fungal meningitis linked to contaminated injections of methylprednisolone acetate produced by the New England Compounding Center."3.81Utility of real-time PCR for detection of Exserohilum rostratum in body and tissue fluids during the multistate outbreak of fungal meningitis and other infections. ( Brandt, ME; Gade, L; Grgurich, DE; Kerkering, TM; Litvintseva, AP, 2015)
"Fungal meningitis due to injections of contaminated methylprednisolone acetate can present with vascular sequelae in immunocompetent individuals."3.79Vascular complications of fungal meningitis attributed to injections of contaminated methylprednisolone acetate. ( Abel, T; Beck, A; Claassen, DO; Jones, P; Kleinfeld, K; Paueksakon, P; Riebau, D, 2013)
"On October 1, 2012, the Department of Defense (DoD) learned of a multistate outbreak of fungal meningitis in persons who received injections of methylprednisolone acetate (MPA) from a single compounding pharmacy."3.79Notes from the field: Department of Defense response to a multistate outbreak of fungal meningitis--United States, October 2012. ( , 2013)
"Administration of epidural steroid injections (ESIs) with contaminated methylprednisolone resulted in an outbreak of fungal meningitis in many locations in the United States."3.79Early clinical observations in prospectively followed patients with fungal meningitis related to contaminated epidural steroid injections. ( Aldoghaither, RA; Baffoe-Bonnie, AW; Bansal, E; Demicco, DD; Garner, DC; Grifasi, ML; Kerkering, TM; Savaliya, VA; Schleupner, CJ; Smith, JA, 2013)
" outbreak of fungal meningitis related to contaminated methylprednisolone acetate."3.79Cerebrospinal fluid (1,3)-β-D-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis. ( Harrison, DM; Kimbrough, DJ; Lyons, JL; Marr, KA; Neumann, H; Roos, KL; Steiner, L; Thakur, KT; Trivedi, JB; Zhang, SX, 2013)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's17 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnold, C1
Smith, RM1
Tipple, M1
Chaudry, MN1
Schaefer, MK1
Park, BJ1
Kleinfeld, K1
Jones, P1
Riebau, D1
Beck, A1
Paueksakon, P1
Abel, T1
Claassen, DO1
Andes, D1
Casadevall, A1
Gauthier, GM1
Keller, NP1
Pappas, PG1
Gade, L1
Grgurich, DE1
Kerkering, TM2
Brandt, ME1
Litvintseva, AP1
Perfect, JR1
Outterson, K1
Shoham, S1
Marr, KA2
Grifasi, ML1
Baffoe-Bonnie, AW1
Bansal, E1
Garner, DC1
Smith, JA1
Demicco, DD1
Schleupner, CJ1
Aldoghaither, RA1
Savaliya, VA1
Lyons, JL2
Gireesh, ED1
Trivedi, JB2
Bell, WR1
Cettomai, D1
Smith, BR1
Karram, S1
Chang, T1
Tochen, L1
Zhang, SX2
McCall, CM1
Pearce, DT1
Carroll, KC1
Chen, L1
Ratchford, JN1
Harrison, DM2
Ostrow, LW1
Stevens, RD1
Roos, KL1
Neumann, H1
Kimbrough, DJ1
Steiner, L1
Thakur, KT1
Bell, BP1
Khabbaz, RF1

Reviews

2 reviews available for methylprednisolone acetate and Fungal Meningitis

ArticleYear
Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans.
    Fungal genetics and biology : FG & B, 2013, Volume: 61

    Topics: Ascomycota; Disease Outbreaks; Drug Contamination; Humans; Iatrogenic Disease; Meningitis, Fungal; M

2013
Lessons learned in the multistate fungal infection outbreak in the United States.
    Current opinion in infectious diseases, 2013, Volume: 26, Issue:6

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Ascomycota; Disease Outbreaks; Drug Contamination; Huma

2013

Other Studies

15 other studies available for methylprednisolone acetate and Fungal Meningitis

ArticleYear
Fungal meningitis outbreak affects over 700.
    The Lancet. Neurology, 2013, Volume: 12, Issue:5

    Topics: Aspergillosis; Disease Outbreaks; Drug Contamination; Humans; Meningitis, Fungal; Methylprednisolone

2013
Spinal and paraspinal infections associated with contaminated methylprednisolone acetate injections - Michigan, 2012-2013.
    MMWR. Morbidity and mortality weekly report, 2013, May-17, Volume: 62, Issue:19

    Topics: Aged; Anti-Inflammatory Agents; Disease Outbreaks; Drug Contamination; Female; Humans; Injections, E

2013
Relapse of fungal meningitis associated with contaminated methylprednisolone.
    The New England journal of medicine, 2013, Jun-27, Volume: 368, Issue:26

    Topics: Aged, 80 and over; Antifungal Agents; Drug Administration Schedule; Drug Contamination; Humans; Inje

2013
Vascular complications of fungal meningitis attributed to injections of contaminated methylprednisolone acetate.
    JAMA neurology, 2013, Sep-01, Volume: 70, Issue:9

    Topics: Aged; Anti-Inflammatory Agents; Antifungal Agents; Brain; Drug Contamination; Female; Humans; Inject

2013
Insights into fungal pathogenesis from the iatrogenic epidemic of Exserohilum rostratum fungal meningitis.
    Fungal genetics and biology : FG & B, 2013, Volume: 61

    Topics: Ascomycota; Disease Outbreaks; Drug Contamination; Humans; Iatrogenic Disease; Immunocompromised Hos

2013
Notes from the field: Department of Defense response to a multistate outbreak of fungal meningitis--United States, October 2012.
    MMWR. Morbidity and mortality weekly report, 2013, Sep-27, Volume: 62, Issue:38

    Topics: Disease Outbreaks; Drug Contamination; Female; Humans; Injections, Epidural; Male; Meningitis, Funga

2013
Utility of real-time PCR for detection of Exserohilum rostratum in body and tissue fluids during the multistate outbreak of fungal meningitis and other infections.
    Journal of clinical microbiology, 2015, Volume: 53, Issue:2

    Topics: Ascomycota; Body Fluids; Disease Outbreaks; Drug Contamination; Drug Monitoring; Female; Humans; Iat

2015
Multistate outbreak of fungal infection associated with injection of methylprednisolone acetate solution from a single compounding pharmacy - United States, 2012.
    MMWR. Morbidity and mortality weekly report, 2012, Oct-19, Volume: 61, Issue:41

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspergillus fumigatus; Centers for Disease

2012
Iatrogenic fungal meningitis: tragedy repeated.
    Annals of internal medicine, 2012, Dec-04, Volume: 157, Issue:11

    Topics: Anti-Inflammatory Agents; Disease Outbreaks; Drug Compounding; Drug Contamination; Humans; Iatrogeni

2012
Regulating compounding pharmacies after NECC.
    The New England journal of medicine, 2012, Nov-22, Volume: 367, Issue:21

    Topics: Drug Compounding; Drug Contamination; Government Regulation; History, 20th Century; History, 21st Ce

2012
Treatment of iatrogenic fungal infections: a black mold defines a new gray zone in medicine.
    Annals of internal medicine, 2013, Feb-05, Volume: 158, Issue:3

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Arthritis; Centers for Disease Control and Prevention,

2013
Early clinical observations in prospectively followed patients with fungal meningitis related to contaminated epidural steroid injections.
    Annals of internal medicine, 2013, Feb-05, Volume: 158, Issue:3

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Disease Outbreaks; Drug Contamination; Follow-Up Studie

2013
Fatal exserohilum meningitis and central nervous system vasculitis after cervical epidural methylprednisolone injection.
    Annals of internal medicine, 2012, Dec-04, Volume: 157, Issue:11

    Topics: Anti-Inflammatory Agents; Ascomycota; Brain; Drug Compounding; Drug Contamination; Fatal Outcome; Fe

2012
Cerebrospinal fluid (1,3)-β-D-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis.
    Journal of clinical microbiology, 2013, Volume: 51, Issue:4

    Topics: Adult; Aged; beta-Glucans; Cerebrospinal Fluid; Drug Contamination; Female; Humans; Iatrogenic Disea

2013
Responding to the outbreak of invasive fungal infections: the value of public health to Americans.
    JAMA, 2013, Mar-06, Volume: 309, Issue:9

    Topics: Anti-Inflammatory Agents; Centers for Disease Control and Prevention, U.S.; Communication; Disease O

2013