Page last updated: 2024-11-07

methylprednisolone acetate and Disease Models, Animal

methylprednisolone acetate has been researched along with Disease Models, Animal in 28 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Osteoporosis was induced by injecting methylprednisolone acetate (21 mg/kg) for the period of 6 weeks, and the rats were treated with cimiracemate A 5 and 10 mg/kg, p."7.91Osteoprotective Effect of Cimiracemate in Glucocorticoid-Induced Osteoporosis by Osteoprotegerin/Receptor Activator of Nuclear Factor κ B/Receptor Activator of Nuclear Factor Kappa-Β Ligand Signaling. ( Ding, Z; Shi, H; Yang, W, 2019)
"This study compared the effect of monotherapy of colistin, tigecycline, and their combination in sepsis model of mice."7.80Carbapenem-resistant Klebsiella pneumoniae sepsis in corticosteroid receipt mice: tigecycline or colistin monotherapy versus tigecycline/colistin combination. ( Ahmed, SS; Alp, E; Demiraslan, H; Dinc, G; Doganay, M; Elmali, F; Metan, G, 2014)
"The study included 20 Sprague-Dawley rats injected once with 20 mg/kg of methylprednisolone acetate into the right gluteus medius muscle to induce osteonecrosis."7.80Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats. ( Göksel, F; Hatay Gölge, U; Kaymaz, B; Kömürcü, E; Nusran, G; Oktay, M, 2014)
"Lacidipine is a potent dihydropyridine calcium channel blocker used for management of hypertension and atherosclerosis."3.96Investigating the potential of utilizing glycerosomes as a novel vesicular platform for enhancing intranasal delivery of lacidipine. ( Abdel Halim, SA; Badr-Eldin, SM; Naguib, MJ; Salah, S, 2020)
"Osteoporosis was induced by injecting methylprednisolone acetate (21 mg/kg) for the period of 6 weeks, and the rats were treated with cimiracemate A 5 and 10 mg/kg, p."3.91Osteoprotective Effect of Cimiracemate in Glucocorticoid-Induced Osteoporosis by Osteoprotegerin/Receptor Activator of Nuclear Factor κ B/Receptor Activator of Nuclear Factor Kappa-Β Ligand Signaling. ( Ding, Z; Shi, H; Yang, W, 2019)
"This study compared the effect of monotherapy of colistin, tigecycline, and their combination in sepsis model of mice."3.80Carbapenem-resistant Klebsiella pneumoniae sepsis in corticosteroid receipt mice: tigecycline or colistin monotherapy versus tigecycline/colistin combination. ( Ahmed, SS; Alp, E; Demiraslan, H; Dinc, G; Doganay, M; Elmali, F; Metan, G, 2014)
"The study included 20 Sprague-Dawley rats injected once with 20 mg/kg of methylprednisolone acetate into the right gluteus medius muscle to induce osteonecrosis."3.80Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats. ( Göksel, F; Hatay Gölge, U; Kaymaz, B; Kömürcü, E; Nusran, G; Oktay, M, 2014)
"Pravastatin, as a statin, was administered in the drinking water for 4 weeks."1.38Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats. ( Kumagai, K; Miyata, N; Niwa, M; Nozaki, Y, 2012)
"Tadalafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5)."1.36Protective effects of tadalafil on experimental spinal cord injury in rats. ( Güven, EO; Oktar, S; Ozgiray, E; Serarslan, Y; Söğüt, S; Yilmaz, N; Yönden, Z; Yurtseven, T, 2010)
"Probucol and warfarin were administered beginning 1 to 2 weeks prior to steroid injection."1.35Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits. ( Hirota, Y; Iwamoto, Y; Kondo, K; Miyanishi, K; Motomura, G; Yamamoto, T, 2008)
"The prevalence and severity of polycystic kidney disease (PKD) induced by glucocorticoids in mice can be predicted by a mathematical "threshold" model."1.29Na-K ATPase activity in murine glucocorticoid induced polycystic kidney disease in vivo. ( Crocker, JF; Ogborn, MR, 1993)
"Strongyloidiasis is the most common endemic helminthiasis in several of the world's industrialized nations, yet relatively little is known about its basic biology and immunobiology because a practical rodent model for the investigation of this clinically important parasitism is lacking."1.29Strongyloides stercoralis: the first rodent model for uncomplicated and hyperinfective strongyloidiasis, the Mongolian gerbil (Meriones unguiculatus). ( Bhopale, VM; Megyeri, Z; Nolan, TJ; Schad, GA, 1993)
"Cyst formation in polycystic kidney disease (PKD) involves proliferation of cyst lining epithelial and changes in trans-epithelial fluid and electrolyte transport."1.29Renal tubule Na,K-ATPase polarity in glucocorticoid-induced polycystic kidney disease. ( Grimm, PC; Ogborn, MR; Sareen, S, 1993)
"Cystic change in polycystic kidney disease (PKD) is associated with epithelial hyperplasia, altered fluid and electrolyte transport, and de-differentiation of renal tubular epithelium."1.29Transforming growth factor alpha and epidermal growth factor expression in experimental murine polycystic kidney disease. ( Ogborn, MR; Sareen, S, 1996)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's6 (21.43)18.2507
2000's6 (21.43)29.6817
2010's12 (42.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Naguib, MJ1
Salah, S1
Abdel Halim, SA1
Badr-Eldin, SM1
Rijsdijk, M1
Agalave, NM1
van Wijck, AJM1
Kalkman, CJ1
Ramachandran, R1
Baharpoor, A1
Svensson, CI1
Yaksh, TL1
Ding, Z1
Shi, H1
Yang, W1
Demiraslan, H1
Dinc, G1
Ahmed, SS1
Elmali, F1
Metan, G1
Alp, E1
Doganay, M1
Zhao, G1
Yamamoto, T4
Motomura, G3
Yamaguchi, R1
Ikemura, S1
Iwasaki, K1
Iwamoto, Y4
Kömürcü, E1
Oktay, M1
Kaymaz, B1
Hatay Gölge, U1
Göksel, F1
Nusran, G1
Pengde, K1
Fuxing, P1
Bin, S1
Jing, Y1
Jingqiu, C1
Miyanishi, K2
Kondo, K1
Hirota, Y1
Kabata, T1
Matsumoto, T1
Yagishita, S1
Wakayama, T1
Iseki, S1
Tomita, K1
Serarslan, Y1
Yönden, Z1
Ozgiray, E1
Oktar, S1
Güven, EO1
Söğüt, S1
Yilmaz, N1
Yurtseven, T1
Wang, L1
Wang, N1
Li, M1
Wang, K1
Miyata, N2
Kumagai, K2
Osaki, M1
Murata, M1
Tomita, M1
Hozumi, A1
Nozaki, Y2
Niwa, M2
Lu, BB1
Li, KH1
Maravilla, P1
Garza-Rodriguez, A1
Gomez-Diaz, B1
Jimenez-Gonzalez, DE1
Toral-Bastida, E1
Martinez-Ocaña, J1
West, B1
Molina, N1
Garcia-Cortes, R1
Kawa-Karasik, S1
Romero-Valdovinos, M1
Avila-Ramirez, G1
Flisser, A1
Ding, S1
Peng, H1
Fang, HS1
Zhou, JL1
Wang, Z1
Kang, PD1
Shen, B1
Yang, J1
Dang, HS1
Pei, FX1
Nishida, K1
Jingushi, S2
Bagwell, CE1
Ferguson, WW1
Kerlin, RL1
Nolan, TJ2
Schad, GA2
Ogborn, MR3
Crocker, JF1
Megyeri, Z1
Bhopale, VM1
Sareen, S2
Grimm, PC1
Irisa, T1
Yamashita, A1
Noguchi, Y1
Saari, H1
Tulamo, RM1
Konttinen, YT1
Sorsa, T1
Sanfilippo, JS1
Cox, JG1
Nealon, NA1
Barrows, GH1
Fujita, H1

Other Studies

28 other studies available for methylprednisolone acetate and Disease Models, Animal

ArticleYear
Investigating the potential of utilizing glycerosomes as a novel vesicular platform for enhancing intranasal delivery of lacidipine.
    International journal of pharmaceutics, 2020, May-30, Volume: 582

    Topics: Administration, Intranasal; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure;

2020
Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model.
    Scandinavian journal of pain, 2017, Volume: 16

    Topics: Animals; Disease Models, Animal; Glucocorticoids; Hyperalgesia; Injections, Spinal; Ligation; Male;

2017
Osteoprotective Effect of Cimiracemate in Glucocorticoid-Induced Osteoporosis by Osteoprotegerin/Receptor Activator of Nuclear Factor κ B/Receptor Activator of Nuclear Factor Kappa-Β Ligand Signaling.
    Pharmacology, 2019, Volume: 103, Issue:3-4

    Topics: Animals; Bone Density Conservation Agents; Bone Remodeling; Cells, Cultured; Cinnamates; Disease Mod

2019
Carbapenem-resistant Klebsiella pneumoniae sepsis in corticosteroid receipt mice: tigecycline or colistin monotherapy versus tigecycline/colistin combination.
    Journal of chemotherapy (Florence, Italy), 2014, Volume: 26, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Carbapenems; Colistin; Disease Models, Animal; Dose-Response Relatio

2014
Cholesterol- and lanolin-rich diets may protect against steroid-induced osteonecrosis in rabbits.
    Acta orthopaedica, 2013, Volume: 84, Issue:6

    Topics: Animals; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Diet; Disease Models, Animal; Fem

2013
Preventive effects of coenzyme Q10 (CoQ10) on steroid-induced osteonecrosis in rats.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:2

    Topics: Animals; Disease Models, Animal; Femur Head; Glucocorticoids; Glutathione; Malondialdehyde; Methylpr

2014
Lovastatin inhibits adipogenesis and prevents osteonecrosis in steroid-treated rabbits.
    Joint bone spine, 2008, Volume: 75, Issue:6

    Topics: Adipocytes; Adipogenesis; Animals; Anticholesteremic Agents; Bone Marrow Cells; Cell Size; Disease M

2008
Risk factors for developing osteonecrosis after prophylaxis in steroid-treated rabbits.
    The Journal of rheumatology, 2008, Volume: 35, Issue:12

    Topics: Adrenal Cortex Hormones; Animals; Anticholesteremic Agents; Anticoagulants; Biomarkers; Chemoprevent

2008
Vascular endothelial growth factor in rabbits during development of corticosteroid-induced osteonecrosis: a controlled experiment.
    The Journal of rheumatology, 2008, Volume: 35, Issue:12

    Topics: Adrenal Cortex Hormones; Animals; Disease Models, Animal; Female; Femur; Femur Head Necrosis; Methyl

2008
Protective effects of tadalafil on experimental spinal cord injury in rats.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carbolines; Disease Models, Animal; Glutathione; Male; Malondiald

2010
To investigate the role of the nervous system of bone in steroid-induced osteonecrosis in rabbits.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:12

    Topics: Animals; Disease Models, Animal; Female; Femur Head; Femur Head Necrosis; Glucocorticoids; Methylpre

2010
Pentosan reduces osteonecrosis of femoral head in SHRSP.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:8

    Topics: Animals; Blood Coagulation; Disease Models, Animal; Femur Head Necrosis; Lipid Metabolism; Male; Met

2010
Lipoic acid prevents steroid-induced osteonecrosis in rabbits.
    Rheumatology international, 2012, Volume: 32, Issue:6

    Topics: Animals; Biomarkers; Cholesterol; Cytoprotection; Disease Models, Animal; Endothelins; Femur; Glutat

2012
Chinchilla laniger can be used as an experimental model for Taenia solium taeniasis.
    Parasitology international, 2011, Volume: 60, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Chinchilla; Disease Models, Animal; Enzyme-Linked Immunosorbent A

2011
Pulsed electromagnetic fields stimulation prevents steroid-induced osteonecrosis in rats.
    BMC musculoskeletal disorders, 2011, Sep-29, Volume: 12

    Topics: Animals; Disease Models, Animal; Electromagnetic Fields; Gene Expression; Glucocorticoids; Injection

2011
Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats.
    Acta orthopaedica, 2012, Volume: 83, Issue:1

    Topics: Adipocytes; Animals; Anti-Inflammatory Agents; Bone Marrow; Disease Models, Animal; Drinking Water;

2012
[Platelet and endothelial cell-derived microparticles in steroid-induced osteonecrosis of the femoral head of rabbit model].
    Zhonghua yi xue za zhi, 2007, Aug-07, Volume: 87, Issue:29

    Topics: Animals; Antithrombin III; Blood Platelets; Disease Models, Animal; E-Selectin; Endothelial Cells; F

2007
Pitavastatin may reduce risk of steroid-induced osteonecrosis in rabbits: a preliminary histological study.
    Clinical orthopaedics and related research, 2008, Volume: 466, Issue:5

    Topics: Adipocytes; Animals; Bone Marrow Cells; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Disease Mod

2008
Lysosomal enzyme levels and tumor growth in steroid-treated rat model.
    The Journal of surgical research, 1980, Volume: 28, Issue:5

    Topics: Animals; Body Weight; Cathepsins; Disease Models, Animal; Female; Liver; Lysosomes; Mammary Neoplasm

1980
Strongyloides stercoralis: histopathology of uncomplicated and hyperinfective strongyloidiasis in the Mongolian gerbil, a rodent model for human strongyloidiasis [corrected].
    International journal for parasitology, 1995, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Gerbillinae; Hemorrhage; Intestinal Disea

1995
Na-K ATPase activity in murine glucocorticoid induced polycystic kidney disease in vivo.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Kidney; Lectins; Male; Methylprednisolone; Methylprednisolo

1993
Strongyloides stercoralis: the first rodent model for uncomplicated and hyperinfective strongyloidiasis, the Mongolian gerbil (Meriones unguiculatus).
    The Journal of infectious diseases, 1993, Volume: 168, Issue:6

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Dogs; Female; Gerbillinae; Male; Methylprednisolo

1993
Renal tubule Na,K-ATPase polarity in glucocorticoid-induced polycystic kidney disease.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, Volume: 41, Issue:4

    Topics: Animals; Cell Polarity; Disease Models, Animal; Fluorescent Antibody Technique; Immunoenzyme Techniq

1993
Transforming growth factor alpha and epidermal growth factor expression in experimental murine polycystic kidney disease.
    Pediatric nephrology (Berlin, Germany), 1996, Volume: 10, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Disease Models, Animal; Epidermal Growth Factor

1996
Bone marrow fat cell enlargement and a rise in intraosseous pressure in steroid-treated rabbits with osteonecrosis.
    Bone, 2002, Volume: 30, Issue:1

    Topics: Adipocytes; Animals; Blood Flow Velocity; Bone Marrow Cells; Cell Size; Disease Models, Animal; Femu

2002
Methylprednisolone acetate induced release of cartilage proteoglycans: determination by high performance liquid chromatography.
    Annals of the rheumatic diseases, 1992, Volume: 51, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Chromatography, High Pressure Liquid; Disea

1992
Comparison of corticosteroid therapy in the prevention of pelvic tissue reaction and adhesion formation.
    International journal of fertility, 1986, Volume: 30, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Betamethasone; Dexamethasone; Disease Mo

1986
[Facial palsy of a short duration induced by compressing the extratemporal facial nerve].
    Nihon Jibiinkoka Gakkai kaiho, 1985, Volume: 88, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Facial Nerve; Facial Paralysis; Guinea Pi

1985